Personal information

Switzerland

Activities

Employment (3)

Eidgenössische Technische Hochschule Zürich: Zurich, ZH, CH

2019-08-01 to present | Head of GEML (FGCZ)
Employment
Source: Self-asserted source
Zacharias Kontarakis

Max Planck Institute for Heart and Lung Research: Bad Nauheim, DE

2012-01 to 2019-07-31 | Post-Doc (Developmental Genetics)
Employment
Source: Self-asserted source
Zacharias Kontarakis

Institute of Molecular Biology and Biotechnology: Heraklion, GR

2011-06 to 2012-01 | Post-Doc (Evolution of Development)
Employment
Source: Self-asserted source
Zacharias Kontarakis

Education and qualifications (3)

University of Crete - Voutes Campus: Heraklion, GR

2006 to 2011 | PhD - Molecular Biology and Biomedicine (IMBB - FoRTH)
Education
Source: Self-asserted source
Zacharias Kontarakis

University of Crete - Voutes Campus: Heraklion, GR

2003 to 2006 | MSc - Molecular Biology and Biomedicine (Biology and Medicine)
Education
Source: Self-asserted source
Zacharias Kontarakis

University of Crete - Voutes Campus: Heraklion, GR

1999 to 2003 | BSc - Biology (Biology)
Education
Source: Self-asserted source
Zacharias Kontarakis

Funding (3)

Small molecules that enhance Prime Editing in therapeutic applications

2024-01 to 2025-12 | Grant
AFM-Téléthon (Paris, FR)
Source: Self-asserted source
Zacharias Kontarakis

The role of miRNAs during adult heart regeneration in zebrafish

2013-01 to 2014-12 | Award
European Molecular Biology Organization (Heidelberg, DE)
GRANT_NUMBER:

ALTF 1229-2012

Source: Self-asserted source
Zacharias Kontarakis

Does regeneration reset the age clock? Assessing cellular senescence in regenerated organs.

2011-01 to 2011-12 | Grant
John S. Latsis Public Benefit Foundation (Athens, GR)
Source: Self-asserted source
Zacharias Kontarakis

Works (27)

Induction of a transcriptional adaptation response by RNA destabilization events

EMBO Reports
2025-03-24 | Journal article
Contributors: Lihan Xie; Gabrielius Jakutis; Christopher M Dooley; Stefan Guenther; Zacharias Kontarakis; Sarah P Howard; Thomas Juan; Didier Y R Stainier
Source: check_circle
Crossref

DISCOVER-Seq: MRE11 ChIP Seq

protocols.io
2023-03-30 | Journal article | Author
Contributors: Jacob Corn; Lilly van de Venn; Zacharias Kontarakis
Source: check_circle
protocols.io

In vivo prime editing of a metabolic liver disease in mice

Science Translational Medicine
2022 | Journal article
EID:

2-s2.0-85126667410

Part of ISSN: 19466242 19466234
Contributors: Böck, D.; Rothgangl, T.; Villiger, L.; Schmidheini, L.; Matsushita, M.; Mathis, N.; Ioannidi, E.; Rimann, N.; Grisch-Chan, H.M.; Kreutzer, S. et al.
Source: Self-asserted source
Zacharias Kontarakis via Scopus - Elsevier

Beyond Mendelian Inheritance: Genetic Buffering and Phenotype Variability

Phenomics
2022-04 | Journal article
Contributors: Andrea Rossi; Zacharias Kontarakis
Source: check_circle
Crossref

Ccn2a is an injury-induced matricellular factor that promotes cardiac regeneration in zebrafish

Development (Cambridge)
2021 | Journal article
EID:

2-s2.0-85100125273

Part of ISSN: 14779129 09501991
Contributors: Mukherjee, D.; Wagh, G.; Mokalled, M.H.; Kontarakis, Z.; Dickson, A.L.; Rayrikar, A.; Günther, S.; Poss, K.D.; Stainier, D.Y.R.; Patra, C.
Source: Self-asserted source
Zacharias Kontarakis via Scopus - Elsevier

Fast but not furious: A streamlined selection method for genome edited cells

bioRxiv
2021 | Other
EID:

2-s2.0-85101294399

Part of ISSN: 26928205
Contributors: Ramachandran, H.; Martins, S.; Kontarakis, Z.; Krutmann, J.; Rossi, A.
Source: Self-asserted source
Zacharias Kontarakis via Scopus - Elsevier

In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels

Nature Biotechnology
2021 | Journal article
EID:

2-s2.0-85106314789

Part of ISSN: 15461696 10870156
Contributors: Rothgangl, T.; Dennis, M.K.; Lin, P.J.C.; Oka, R.; Witzigmann, D.; Villiger, L.; Qi, W.; Hruzova, M.; Kissling, L.; Lenggenhager, D. et al.
Source: Self-asserted source
Zacharias Kontarakis via Scopus - Elsevier

PnB Designer: a web application to design prime and base editor guide RNAs for animals and plants

BMC Bioinformatics
2021 | Journal article
EID:

2-s2.0-85101922254

Part of ISSN: 14712105
Contributors: Siegner, S.M.; Karasu, M.E.; Schröder, M.S.; Kontarakis, Z.; Corn, J.E.
Source: Self-asserted source
Zacharias Kontarakis via Scopus - Elsevier

Treatment of a metabolic liver disease by in vivo prime editing in mice

bioRxiv
2021 | Other
EID:

2-s2.0-85115419551

Part of ISSN: 26928205
Contributors: Böck, D.; Rothgangl, T.; Villiger, L.; Schmidheini, L.; Mathis, N.; Ioannidi, E.; Kreutzer, S.; Kontarakis, Z.; Rimann, N.; Grisch-Chan, H.M. et al.
Source: Self-asserted source
Zacharias Kontarakis via Scopus - Elsevier

Fast but not furious: a streamlined selection method for genome-edited cells

Life Science Alliance
2021-06 | Journal article
Contributors: Haribaskar Ramachandran; Soraia Martins; Zacharias Kontarakis; Jean Krutmann; Andrea Rossi
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Tie1 regulates zebrafish cardiac morphogenesis through Tolloid-like 1 expression

Developmental Biology
2021-01 | Journal article
Contributors: Claudia Carlantoni; Srinivas Allanki; Zacharias Kontarakis; Andrea Rossi; Janett Piesker; Stefan Günther; Didier Y.R. Stainier
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Genetics in Light of Transcriptional Adaptation

Trends in Genetics
2020 | Journal article
EID:

2-s2.0-85090717197

Part of ISSN: 13624555 01689525
Contributors: Kontarakis, Z.; Stainier, D.Y.R.
Source: Self-asserted source
Zacharias Kontarakis via Scopus - Elsevier

Transcriptional adaptation in caenorhabditis elegans

eLife
2020 | Journal article
EID:

2-s2.0-85077941721

Part of ISSN: 2050084X
Contributors: Serobyan, V.; Kontarakis, Z.; El-Brolosy, M.A.; Welker, J.M.; Tolstenkov, O.; Saadeldein, A.M.; Retzer, N.; Gottschalk, A.; Wehman, A.M.; Stainier, D.Y.R.
Source: Self-asserted source
Zacharias Kontarakis via Scopus - Elsevier

Genetic compensation triggered by mutant mRNA degradation

Nature
2019 | Journal article
EID:

2-s2.0-85063960455

Part of ISSN: 14764687 00280836
Contributors: El-Brolosy, M.A.; Kontarakis, Z.; Rossi, A.; Kuenne, C.; Günther, S.; Fukuda, N.; Kikhi, K.; Boezio, G.L.M.; Takacs, C.M.; Lai, S.-L. et al.
Source: Self-asserted source
Zacharias Kontarakis via Scopus - Elsevier

Mir-126 is a conserved modulator of lymphatic development

Developmental Biology
2018 | Journal article
EID:

2-s2.0-85044299599

Part of ISSN: 1095564X 00121606
Contributors: Kontarakis, Z.; Rossi, A.; Ramas, S.; Dellinger, M.T.; Stainier, D.Y.R.
Source: Self-asserted source
Zacharias Kontarakis via Scopus - Elsevier

Genetic compensation is triggered by mutant mRNA degradation

2018-05-22 | Other
Contributors: Mohamed A. El-Brolosy; Andrea Rossi; Zacharias Kontarakis; Carsten Kuenne; Stefan Günther; Nana Fukuda; Carter Takacs; Shih-Lei Lai; Ryuichi Fukuda; Claudia Gerri et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Transient cardiomyocyte fusion regulates cardiac development in zebrafish

Nature Communications
2017-11-15 | Journal article
Contributors: Suphansa Sawamiphak; Zacharias Kontarakis; Alessandro Filosa; Sven Reischauer; Didier Y. R. Stainier
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

The zebrafish ventricle: A hub of cardiac endothelial cells for in vitro cell behavior studies

Scientific Reports
2017-06-02 | Journal article
Part of ISSN: 2045-2322
Contributors: Chinmoy Patra; Zacharias Kontarakis; Harmandeep Kaur; Amey Rayrikar; Debanjan Mukherjee; Didier Y. R. Stainier
Source: Self-asserted source
Zacharias Kontarakis via Crossref Metadata Search
grade
Preferred source (of 2)‎

Genetic compensation induced by deleterious mutations but not gene knockdowns

Nature
2015-07 | Journal article
Part of ISSN: 0028-0836
Contributors: Andrea Rossi; Zacharias Kontarakis; Claudia Gerri; Hendrik Nolte; Soraya Hölper; Marcus Krüger; Didier Y. R. Stainier
Source: Self-asserted source
Zacharias Kontarakis via Crossref Metadata Search
grade
Preferred source (of 2)‎

Making Sense of Anti-Sense Data

Developmental Cell
2015-01 | Journal article
Part of ISSN: 1534-5807
Contributors: Didier Y.R. Stainier; Zacharias Kontarakis; Andrea Rossi
Source: Self-asserted source
Zacharias Kontarakis via Crossref Metadata Search
grade
Preferred source (of 2)‎

Interferon Gamma Signaling Positively Regulates Hematopoietic Stem Cell Emergence

Developmental Cell
2014 | Journal article
Part of ISSN: 1534-5807
Contributors: Suphansa Sawamiphak; Zacharias Kontarakis; Didier Y.R. Stainier
Source: Self-asserted source
Zacharias Kontarakis via Crossref Metadata Search
grade
Preferred source (of 2)‎

Transgenesis in Non-model Organisms: The Case of Parhyale

Hox Genes
2014 | Other
Part of ISBN: 9781493912414
Part of ISSN: 1064-3745
Contributors: Zacharias Kontarakis; Anastasios Pavlopoulos
Source: Self-asserted source
Zacharias Kontarakis via Crossref Metadata Search
grade
Preferred source (of 2)‎

Reconfiguring gene traps for new tasks using iTRAC

Fly
2011-10-01 | Journal article
Part of ISSN: 1933-6934
Contributors: Zacharias Kontarakis; Nikolaos Konstantinides; Anastasios Pavlopoulos; Michalis Averof
Source: Self-asserted source
Zacharias Kontarakis via Crossref Metadata Search
grade
Preferred source (of 2)‎

A versatile strategy for gene trapping and trap conversion in emerging model organisms

Development
2011-05 | Journal article
Part of ISSN: 0950-1991
Contributors: Z. Kontarakis; A. Pavlopoulos; A. Kiupakis; N. Konstantinides; V. Douris; M. Averof
Source: Self-asserted source
Zacharias Kontarakis via Crossref Metadata Search
grade
Preferred source (of 2)‎

Knockdown of Parhyale Ultrabithorax recapitulates evolutionary changes in crustacean appendage morphology

Proceedings of the National Academy of Sciences
2009-08-04 | Journal article
Part of ISSN: 0027-8424
Contributors: D. M. Liubicich; J. M. Serano; A. Pavlopoulos; Z. Kontarakis; M. E. Protas; E. Kwan; S. Chatterjee; K. D. Tran; M. Averof; N. H. Patel
Source: Self-asserted source
Zacharias Kontarakis via Crossref Metadata Search
grade
Preferred source (of 2)‎

Probing the evolution of appendage specialization by Hox gene misexpression in an emerging model crustacean

Proceedings of the National Academy of Sciences
2009-08-04 | Journal article
Part of ISSN: 0027-8424
Contributors: A. Pavlopoulos; Z. Kontarakis; D. M. Liubicich; J. M. Serano; M. Akam; N. H. Patel; M. Averof
Source: Self-asserted source
Zacharias Kontarakis via Crossref Metadata Search
grade
Preferred source (of 2)‎

Expression of hunchback during trunk segmentation in the branchiopod crustacean Artemia franciscana

Development Genes and Evolution
2005-10 | Journal article
Part of ISSN: 0949-944X
Contributors: Zacharias Kontarakis; Tijana Copf; Michalis Averof
Source: Self-asserted source
Zacharias Kontarakis via Crossref Metadata Search
grade
Preferred source (of 2)‎

Peer review (2 reviews for 2 publications/grants)

Review activity for Cell systems. (1)
Review activity for Faculty Opinions (1)