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Scopus Author ID: 55991178400

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Works (34)

Divergent roles of m6A in orchestrating brown and white adipocyte transcriptomes and systemic metabolism

Nature Communications
2025-01-09 | Journal article
DOI: 10.1038/s41467-024-55694-w
Contributors: Ling Xiao; Dario F. De Jesus; Cheng-Wei Ju; Jiang-Bo Wei; Jiang Hu; Ava DiStefano-Forti; Valeria Salerno Gonzales; Tadataka Tsuji; Siying Wei; Matthias Blüher et al.
Source: check_circle
Crossref

m6A mRNA methylation by METTL14 regulates early pancreatic cell differentiation

The EMBO Journal
2024-09-25 | Journal article
DOI: 10.1038/s44318-024-00213-2
Contributors: Sevim Kahraman; Dario F De Jesus; Jiangbo Wei; Natalie K Brown; Zhongyu Zou; Jiang Hu; Mehdi Pirouz; Richard I Gregory; Chuan He; Rohit N Kulkarni
Source: check_circle
Crossref

Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes

Nature Cell Biology
2024-03 | Journal article
DOI: 10.1038/s41556-024-01368-0
Contributors: Dario F. De Jesus; Zijie Zhang; Natalie K. Brown; Xiaolu Li; Ling Xiao; Jiang Hu; Matthew J. Gaffrey; Garrett Fogarty; Sevim Kahraman; Jiangbo Wei et al.
Source: check_circle
Crossref

Deficiency of the metabolic enzyme SCHAD in pancreatic β-cells promotes amino acid–sensitive hypoglycemia

Journal of Biological Chemistry
2023 | Journal article
DOI: 10.1016/j.jbc.2023.104986
EID:

2-s2.0-85166060531

Part of ISSN: 1083351X 00219258
Contributors: St-Louis, J.L.; El Jellas, K.; Velasco, K.; Slipp, B.A.; Hu, J.; Helgeland, G.; Steine, S.J.; De Jesus, D.F.; Kulkarni, R.N.; Molven, A.
Source: Self-asserted source
Dario F De Jesus via Scopus - Elsevier

Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways

Cell Metabolism
2023 | Journal article
DOI: 10.1016/j.cmet.2023.05.007
EID:

2-s2.0-85164351946

Part of ISSN: 19327420 15504131
Contributors: Basile, G.; Vetere, A.; Hu, J.; Ijaduola, O.; Zhang, Y.; Liu, K.-C.; Eltony, A.M.; De Jesus, D.F.; Fukuda, K.; Doherty, G. et al.
Source: Self-asserted source
Dario F De Jesus via Scopus - Elsevier

Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses

eLife
2023 | Journal article
DOI: 10.7554/eLife.85056
EID:

2-s2.0-85173681929

Part of ISSN: 2050084X
Contributors: Kahraman, S.; Shibue, K.; De Jesus, D.F.; Kim, H.; Hu, J.; Manna, D.; Wagner, B.; Choudhary, A.; Kulkarni, R.N.
Source: Self-asserted source
Dario F De Jesus via Scopus - Elsevier

m<sup>6</sup>A mRNA Methylation in Brown Adipose Tissue Regulates Systemic Insulin Sensitivity via an Inter-Organ Prostaglandin Signaling Axis

bioRxiv
2023 | Other
DOI: 10.1101/2023.05.26.542169
EID:

2-s2.0-85162033337

Part of ISSN: 26928205
Contributors: Xiao, L.; De Jesus, D.F.; Ju, C.-W.; Wei, J.-B.; Hu, J.; DiStefanoForti, A.; Tsuji, T.; Cero, C.; Männistö, V.; Manninen, S.M. et al.
Source: Self-asserted source
Dario F De Jesus via Scopus - Elsevier

m<sup>6</sup>A mRNA Methylation Regulates Early Pancreatic β-Cell Differentiation

bioRxiv
2023 | Other
DOI: 10.1101/2023.08.03.551675
EID:

2-s2.0-85171674105

Part of ISSN: 26928205
Contributors: Kahraman, S.; De Jesus, D.F.; Wei, J.; Brown, N.K.; Zou, Z.; Hu, J.; He, C.; Kulkarni, R.N.
Source: Self-asserted source
Dario F De Jesus via Scopus - Elsevier

NREP contributes to development of NAFLD by regulating one-carbon metabolism in primary human hepatocytes

Cell Chemical Biology
2023 | Journal article
DOI: 10.1016/j.chembiol.2023.06.001
EID:

2-s2.0-85167794225

Part of ISSN: 24519448 24519456
Contributors: De Jesus, D.F.; Kimura, T.; Gupta, M.K.; Kulkarni, R.N.
Source: Self-asserted source
Dario F De Jesus via Scopus - Elsevier

Redox Regulation of m<sup>6</sup>A Methyltransferase METTL3 in Human β-cells Controls the Innate Immune Response in Type 1 Diabetes

bioRxiv
2023 | Other
DOI: 10.1101/2023.02.16.528701
EID:

2-s2.0-85152145644

Part of ISSN: 26928205
Contributors: De Jesus, D.F.; Zhang, Z.; Brown, N.K.; Li, X.; Gaffrey, M.J.; Kahraman, S.; Wei, J.; Hu, J.; Basile, G.; Xiao, L. et al.
Source: Self-asserted source
Dario F De Jesus via Scopus - Elsevier
grade
Preferred source (of 2)‎

E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance

Cell Reports
2022 | Journal article
DOI: 10.1016/j.celrep.2022.111436
EID:

2-s2.0-85139279877

Part of ISSN: 22111247
Contributors: Shirakawa, J.; Togashi, Y.; Basile, G.; Okuyama, T.; Inoue, R.; Fernandez, M.; Kyohara, M.; De Jesus, D.F.; Goto, N.; Zhang, W. et al.
Source: Self-asserted source
Dario F De Jesus via Scopus - Elsevier

Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses

bioRxiv
2022 | Other
DOI: 10.1101/2022.11.27.518097
EID:

2-s2.0-85146921837

Part of ISSN: 26928205
Contributors: Kahraman, S.; Shibue, K.; De Jesus, D.F.; Hu, J.; Manna, D.; Wagner, B.K.; Choudhary, A.; Kulkarni, R.N.
Source: Self-asserted source
Dario F De Jesus via Scopus - Elsevier

Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b

Science Translational Medicine
2022 | Journal article
DOI: 10.1126/scitranslmed.abh3831
EID:

2-s2.0-85126857111

Part of ISSN: 19466242 19466234
Contributors: Patel, S.J.; Liu, N.; Piaker, S.; Gulko, A.; Andrade, M.L.; Heyward, F.D.; Sermersheim, T.; Edinger, N.; Srinivasan, H.; Emont, M.P. et al.
Source: Self-asserted source
Dario F De Jesus via Scopus - Elsevier

Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice

Nature Communications
2022 | Journal article
DOI: 10.1038/s41467-022-34259-9
EID:

2-s2.0-85142865573

Part of ISSN: 20411723
Contributors: Wang, X.; Li, Y.; Qiang, G.; Wang, K.; Dai, J.; McCann, M.; Munoz, M.D.; Gil, V.; Yu, Y.; Li, S. et al.
Source: Self-asserted source
Dario F De Jesus via Scopus - Elsevier

scEMC10, a novel circulating inhibitor of adipocyte thermogenesis, is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity

Research Square
2021 | Other
DOI: 10.21203/rs.3.rs-869957/v1
EID:

2-s2.0-85166887610
Contributors: Wang, X.; Qiang, G.; Li, Y.; Wang, K.; Dai, J.; McCann, M.; Gil, V.; Yu, Y.; Li, S.; Yang, Z. et al.
Source: Self-asserted source
Dario F De Jesus via Scopus - Elsevier

A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism

Nature communications
2020 | Journal article
DOI: 10.1038/s41467-020-14323-y
Part of ISSN: 2041-1723
Source: Self-asserted source
Dario F De Jesus

Luseogliflozin increases beta cell proliferation through humoral factors that activate an insulin receptor- and IGF-1 receptor-independent pathway

Diabetologia
2020 | Journal article
DOI: 10.1007/s00125-019-05071-w
Part of ISSN: 0012-186X
Source: Self-asserted source
Dario F De Jesus
grade
Preferred source (of 2)‎

More is better: combinatorial therapy to restore β-cell function in diabetes

Nature metabolism
2020 | Journal article
DOI: 10.1038/s42255-020-0176-y
Part of ISSN: 2522-5812
Source: Self-asserted source
Dario F De Jesus
grade
Preferred source (of 3)‎

Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice

Journal of Clinical Investigation
2020 | Journal article
DOI: 10.1172/JCI127502
EID:

2-s2.0-85084231270

Part of ISSN: 15588238 00219738
Contributors: de Jesus, D.F.; Orime, K.; Kaminska, D.; Kimura, T.; Basile, G.; Wang, C.-H.; Haertle, L.; Riemens, R.; Brown, N.K.; Hu, J. et al.
Source: Self-asserted source
Dario F De Jesus via Scopus - Elsevier
grade
Preferred source (of 2)‎

"Omics" and "epi-omics" underlying the β-cell adaptation to insulin resistance

Molecular metabolism
2019 | Journal article
DOI: 10.1016/j.molmet.2019.06.003
Part of ISSN: 2212-8778
Source: Self-asserted source
Dario F De Jesus
grade
Preferred source (of 2)‎

Human duct cells contribute to β cell compensation in insulin resistance

JCI insight
2019 | Journal article
DOI: 10.1172/jci.insight.99576
Part of ISSN: 2379-3708
Source: Self-asserted source
Dario F De Jesus
grade
Preferred source (of 3)‎

Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes

Nature metabolism
2019 | Journal article
DOI: 10.1038/s42255-019-0061-8
Part of ISSN: 2522-5812
Source: Self-asserted source
Dario F De Jesus
grade
Preferred source (of 3)‎

Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes

Diabetes
2019 | Journal article
DOI: 10.2337/db17-0821
Part of ISSN: 0012-1797
Source: Self-asserted source
Dario F De Jesus
grade
Preferred source (of 2)‎

m&lt;sup&gt;6&lt;/sup&gt;A mRNA Methylation Regulates Human β-Cell Biology in Physiological States and in Type 2 Diabetes

Nature metabolism
2019 | Journal article
DOI: 10.1038/s42255-019-0089-9
Part of ISSN: 2522-5812
Source: Self-asserted source
Dario F De Jesus
grade
Preferred source (of 3)‎

RADAR: differential analysis of MeRIP-seq data with a random effect model

Genome biology
2019 | Journal article
DOI: 10.1186/s13059-019-1915-9
Part of ISSN: 1474-7596
Source: Self-asserted source
Dario F De Jesus
grade
Preferred source (of 2)‎

RADAR: Differential analysis of MeRIP-seq data with a random effect model

bioRxiv
2019 | Other
DOI: 10.1101/867903
EID:

2-s2.0-85095632952

Part of ISSN: 26928205
Contributors: Zhang, Z.; Zhan, Q.; Eckert, M.; Zhu, A.; Chryplewicz, A.; de Jesus, D.F.; Ren, D.; Kulkarni, R.N.; Lengyel, E.; He, C. et al.
Source: Self-asserted source
Dario F De Jesus via Scopus - Elsevier

Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation

Molecular metabolism
2018 | Journal article
DOI: 10.1016/j.molmet.2018.09.003
Part of ISSN: 2212-8778
Source: Self-asserted source
Dario F De Jesus
grade
Preferred source (of 3)‎

Exploring inter-organ crosstalk to uncover mechanisms that regulate β-cell function and mass

European Journal of Clinical Nutrition
2017 | Journal article
DOI: 10.1038/ejcn.2017.13
EID:

2-s2.0-85015191316

Part of ISSN: 14765640 09543007
Contributors: Shirakawa, J.; De Jesus, D.F.; Kulkarni, R.N.
Source: Self-asserted source
Dario F De Jesus via Scopus - Elsevier

SerpinB1 Promotes Pancreatic β Cell Proliferation

Cell metabolism
2016 | Journal article
DOI: 10.1016/j.cmet.2015.12.001
Part of ISSN: 1550-4131
Source: Self-asserted source
Dario F De Jesus
grade
Preferred source (of 2)‎

Compensatory Islet Response to Insulin Resistance Revealed by Quantitative Proteomics

Journal of proteome research
2015 | Journal article
DOI: 10.1021/acs.jproteome.5b00587
Part of ISSN: 1535-3893
Source: Self-asserted source
Dario F De Jesus
grade
Preferred source (of 2)‎

Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts

Stem cells translational medicine
2015 | Journal article
DOI: 10.5966/sctm.2014-0217
Part of ISSN: 2157-6564
Source: Self-asserted source
Dario F De Jesus
grade
Preferred source (of 2)‎

Epigenetic modifiers of islet function and mass

Trends in endocrinology and metabolism: TEM
2014 | Journal article
DOI: 10.1016/j.tem.2014.08.006
Part of ISSN: 1043-2760
Source: Self-asserted source
Dario F De Jesus
grade
Preferred source (of 2)‎

Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring

American journal of physiology. Endocrinology and metabolism
2014 | Journal article
DOI: 10.1152/ajpendo.00210.2014
Part of ISSN: 0193-1849
Source: Self-asserted source
Dario F De Jesus
grade
Preferred source (of 2)‎

Soluble factors secreted by T cells promote β-cell proliferation

Diabetes
2014 | Journal article
DOI: 10.2337/db13-0204
Part of ISSN: 0012-1797
Source: Self-asserted source
Dario F De Jesus
grade
Preferred source (of 2)‎

Peer review (4 reviews for 3 publications/grants)

Review activity for European journal of nutrition. (1)
Review activity for Metabolism, clinical and experimental. (2)
Review activity for Molecular biology reports. (1)
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