Personal information

Websites & social links

https://www.linkedin.com/in/emilio-medina-rivero-8609948a/

Other IDs

Scopus Author ID: 24462530400

Keywords

Biotherapeutics

Countries

Mexico

Biography

My management competencies, skills and knowledge are related to:

Manage and support an interdisciplinary team for molecular and functional characterization of protein therapeutics, early and late stage process development, formulation development and accelerated stability testing. CTD Preparation for biotherapeutics according to ICH.

Activities

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Employment (4)

Landsteiner Scientific: Mexico City, DF, MX

2021-02-01 to present | Deputy Director (R&D)
Employment
Source: Self-asserted source
Emilio Medina-Rivero

Instituto Politécnico Nacional: Ciudad de Mexico, Distrito Federal, MX

2016-11 to 2020-05 | Technical-Scientific Director (Unidad de Desarrollo e Investigación en Bioprocesos (UDIBI)
Employment
Source: Self-asserted source
Emilio Medina-Rivero

Probiomed SA de CV: México DF, Mexico, MX

2008-05 to 2016-10 | Principal Scientist (Research and Development)
Employment
Source: Self-asserted source
Emilio Medina-Rivero

Probiomed SA de CV: México DF, MX

2007-01 to 2008-05 | Associate Scientist
Employment
Source: Self-asserted source
Emilio Medina-Rivero

Education and qualifications (4)

ICAMI: México, MX

2012 to 2013 | Management Competencies Improvement
Education
Source: Self-asserted source
Emilio Medina-Rivero

Institute for Scientific and Technological Research of San Luis Potosi, IPICYT: San Luis Potosí, MX

2003 to 2006 | PhD (Molecular Biology)
Education
Source: Self-asserted source
Emilio Medina-Rivero

Universidad Autónoma Metropolitana, UAM-I: Mexico city, MX

2000 to 2002 | MSc (Biotechnology)
Education
Source: Self-asserted source
Emilio Medina-Rivero

Instituto Tecnológico de Mérida, ITM: Mérida, Yucatán, MX

1996 to 2000 | Engineer (Biochemical Engineering)
Education
Source: Self-asserted source
Emilio Medina-Rivero

Works (45)

Efficient enzymatic hydrolysis for enriching the antioxidant content of agro‐food industrial residues

JSFA reports
2023-09 | Journal article
DOI: 10.1002/jsf2.145
Contributors: Eriko Padron‐Regalado; Eida Elena Mejía‐Olvera; Allan Mauricio Marruffo‐Carmona; José Carlos Solís‐Suárez; Darío Peralta‐Agapito; Emilio Medina‐Rivero
Source: check_circle
Crossref

Characterization of a Complex Mixture of Immunomodulator Peptides Obtained from Autologous Urine

Journal of Immunology Research
2020-04-02 | Journal article
DOI: 10.1155/2020/3683782
Contributors: Alberto Fragoso; Mérida Pedraza-Jiménez; Laura Espinoza-González; María Luisa Ceja-Mendoza; Hugo Sánchez-Mercado; Gloria Robles-Pérez; Julio Granados; Emilio Medina-Rivero
Source: check_circle
Crossref

Identity Profiling of Complex Mixtures of Peptide Products by Structural and Mass Mobility Orthogonal Analysis

Analytical Chemistry
2019-11-19 | Journal article
DOI: 10.1021/acs.analchem.9b02873
Contributors: Said Vázquez-Leyva; Luis Vallejo-Castillo; Carlos A. López-Morales; José Enrique Herbert-Pucheta; L. Gerardo Zepeda-Vallejo; Marco Velasco-Velázquez; Lenin Pavón; Sonia M. Pérez-Tapia; Emilio Medina-Rivero
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Crossref

Validation of a Cell Proliferation Assay to Assess the Potency of a Dialyzable Leukocyte Extract Intended for Batch Release

Molecules
2019-09-20 | Journal article
DOI: 10.3390/molecules24193426
Contributors: Gregorio Carballo-Uicab; José E. Linares-Trejo; Gabriela Mellado-Sánchez; Carlos A. López-Morales; Marco Velasco-Velázquez; Lenin Pavón; Sergio Estrada-Parra; Sonia Mayra Pérez-Tapia; Emilio Medina-Rivero
Source: check_circle
Crossref

Development of Functional Antibodies Directed to Human Dialyzable Leukocyte Extract (Transferon®)

Journal of Immunology Research
2019-05-16 | Journal article
DOI: 10.1155/2019/2754920
Contributors: Gabriela Mellado-Sánchez; Juan José Lázaro-Rodríguez; Sandra Avila; Luis Vallejo-Castillo; Said Vázquez-Leyva; Gregorio Carballo-Uicab; Marco Velasco-Velázquez; Emilio Medina-Rivero; Lenin Pavón; Rommel Chacón-Salinas et al.
Source: check_circle
Crossref

CD80 Expression Correlates with IL-6 Production in THP-1-Like Macrophages Costimulated with LPS and Dialyzable Leukocyte Extract (Transferon®)

Journal of Immunology Research
2019-04-10 | Journal article
DOI: 10.1155/2019/2198508
Contributors: Alexis P. Jiménez-Uribe; Hugo Valencia-Martínez; Gregorio Carballo-Uicab; Luis Vallejo-Castillo; Emilio Medina-Rivero; Rommel Chacón-Salinas; Lenin Pavón; Marco A. Velasco-Velázquez; Gabriela Mellado-Sánchez; Sergio Estrada-Parra et al.
Source: check_circle
Crossref

Response to: Comment on “New Alternatives for Autoimmune Disease Treatments: Physicochemical and Clinical Comparability of Biosimilar Etanercept”

Journal of Immunology Research
2018 | Journal article
DOI: 10.1155/2018/6156024
Contributors: Mariana P. Miranda-Hernández; Carlos A. López-Morales; Francisco C. Perdomo-Abúndez; Rodolfo D. Salazar-Flores; Nancy D. Ramírez-Ibanez; Nestor O. Pérez; Aaron Molina-Pérez; Jorge Revilla-Beltri; Emilio Medina-Rivero; Luis F. Flores-Ortiz
Source: check_circle
Crossref

Development and validation of a bioassay to evaluate binding of adalimumab to cell membrane-anchored TNFα using flow cytometry detection

Journal of Pharmaceutical and Biomedical Analysis
2018-06 | Journal article
DOI: 10.1016/j.jpba.2018.03.057
Contributors: Rosa Camacho-Sandoval; Eréndira N. Sosa-Grande; Edith González-González; Alejandra Tenorio-Calvo; Carlos A. López-Morales; Marco Velasco-Velázquez; Lenin Pavón-Romero; Sonia Mayra Pérez-Tapia; Emilio Medina-Rivero
Source: check_circle
Crossref

Capillary Electrophoresis Separation of Monoclonal Antibody Isoforms Using a Neutral Capillary

Journal of Visualized Experiments
2017 | Journal article
DOI: doi:10.3791/55082
Source: Self-asserted source
Emilio Medina-Rivero

Extensive preclinical evaluation of an infliximab biosimilar candidate

European Journal of Pharmaceutical Sciences
2017 | Journal article
DOI: doi.org/10.1016/j.ejps.2017.01.038
Source: Self-asserted source
Emilio Medina-Rivero

Process signatures in glatiramer acetate synthesis: structural and functional relationships

SCIENTIFIC REPORTS
2017 | Journal article
DOI: DOI:10.1038/s41598-017-12416-1
Source: Self-asserted source
Emilio Medina-Rivero

Performance of an immobilized recombinant leucine aminopeptidase after storage in ethanol–water solution

Biocatalysis and Biotransformation
2017-11-02 | Journal article
DOI: 10.1080/10242422.2017.1355364
Contributors: Ana V. Hernández-Moreno; Victor Pérez Medina Martínez; Lidia E. Ramírez-Ramos; Carlos A. López-Morales; Mario E. Abad-Javier; Gabriel Luna-Barcenas; Néstor O. Pérez; Luis F. Flores-Ortiz; Francisco Villaseñor-Ortega; Emilio Medina-Rivero
Source: check_circle
Crossref

Design of a strong cation exchange methodology for the evaluation of charge heterogeneity in glatiramer acetate

Journal of Pharmaceutical and Biomedical Analysis
2017-01 | Journal article
DOI: 10.1016/j.jpba.2016.10.002
Contributors: Víctor R. Campos-García; Carlos A. López-Morales; Eleuterio Benites-Zaragoza; Armando Jiménez-Miranda; Carlos E. Espinosa-de la Garza; Daniel Herrera-Fernández; Jesús Padilla-Calderón; Néstor O. Pérez; Luis F. Flores-Ortiz; E. Medina-Rivero
Source: check_circle
Crossref

Transferon™, a peptide mixture with immunomodulatory properties is not immunogenic when administered with various adjuvants

Journal of Immunotoxicology
2017-01-01 | Journal article
DOI: 10.1080/1547691X.2017.1346009
Contributors: Sandra Avila; Leslie Muñoz-García; Said Vázquez-Leyva; Nohemí Salinas-Jazmín; Emilio Medina-Rivero; Lenin Pavón; Gabriela Mellado-Sánchez; Rommel Chacón-Salinas; Sergio Estrada-Parra; Luis Vallejo-Castillo et al.
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Crossref

Characterization and comparability of biosimilars: A filgrastim case of study and regulatory perspectives for Latin America

Electronic Journal of Biotechnology
2016 | Journal article
DOI: 10.1016/j.ejbt.2016.10.003
Source: Self-asserted source
Emilio Medina-Rivero

Immunomodulatory Effects Mediated by Dopamine

Journal of Immunology Research
2016 | Journal article
DOI: 10.1155/2016/3160486
Contributors: Rodrigo Arreola; Samantha Alvarez-Herrera; Gilberto Pérez-Sánchez; Enrique Becerril-Villanueva; Carlos Cruz-Fuentes; Enrique Octavio Flores-Gutierrez; María Eugenia Garcés-Alvarez; Dora Luz de la Cruz-Aguilera; Emilio Medina-Rivero; Gabriela Hurtado-Alvarado et al.
Source: check_circle
Crossref

New Alternatives for Autoimmune Disease Treatments: Physicochemical and Clinical Comparability of Biosimilar Etanercept

Journal of Immunology Research
2016 | Journal article
DOI: 10.1155/2016/9697080
Source: Self-asserted source
Emilio Medina-Rivero

Optimization of a Recombinant Human Growth Hormone Purification Process Using Quality by Design

Preparative Biochemistry and Biotechnology
2016 | Journal article
DOI: 10.1080/10826068.2015.1135467
Source: Self-asserted source
Emilio Medina-Rivero

Physicochemical Characteristics of Transferon™Batches

BioMed Research International
2016 | Journal article
DOI: 10.1155/2016/7935181
Contributors: Emilio Medina-Rivero; Luis Vallejo-Castillo; Said Vázquez-Leyva; Gilberto Pérez-Sánchez; Liliana Favari; Marco Velasco-Velázquez; Sergio Estrada-Parra; Lenin Pavón; Sonia Mayra Pérez-Tapia
Source: check_circle
Crossref

Theoretical approximations and experimental extinction coefficients of biopharmaceuticals

Analytical Bioanalytical Chemistry
2016 | Journal article
DOI: DOI 10.1007/s00216-015-9261-6
Source: Self-asserted source
Emilio Medina-Rivero

VALIDACIO´ N DE UN ME´ TODO ESPECTROFOTOME´ TRICO PARA CUANTIFICACIO´ N DE TIOLES LIBRES EN FILGRASTIM VALIDATION OF A SPECTROPHOTOMETRIC METHOD FOR FREE THIOLS QUANTIFICATION IN FILGRASTIM

Revista Mexicana de Ingeniería Química
2016 | Journal article
ISSN: 2395-8472
Source: Self-asserted source
Emilio Medina-Rivero

Analysis of therapeutic proteins and peptides using multiangle light scattering coupled to ultra high performance liquid chromatography

2015 | Journal article
DOI:

10.1002/jssc.201400863

EID:

2-s2.0-84926669540
Contributors: Espinosa-de la Garza, C.E.; Miranda-Hernández, M.P.; Acosta-Flores, L.; Pérez, N.O.; Flores-Ortiz, L.F.; Medina-Rivero, E.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier

Assessment of Physicochemical Properties of Rituximab Related to Its Immunomodulatory Activity

Journal of Immunology Research
2015 | Journal article
DOI: 10.1155/2015/910763
Contributors: Mariana P. Miranda-Hernández; Carlos A. López-Morales; Nancy D. Ramírez-Ibáñez; Nelly Piña-Lara; Nestor O. Pérez; Aarón Molina-Pérez; Jorge Revilla-Beltri; Luis F. Flores-Ortiz; Emilio Medina-Rivero
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Crossref

Herpes Murine Model as a Biological Assay to Test Dialyzable Leukocyte Extracts Activity

Journal of Immunology Research
2015 | Journal article
DOI: 10.1155/2015/146305
Contributors: Nohemí Salinas-Jazmín; Sergio Estrada-Parra; Miguel Angel Becerril-García; Alberto Yairh Limón-Flores; Said Vázquez-Leyva; Emilio Medina-Rivero; Lenin Pavón; Marco Antonio Velasco-Velázquez; Sonia Mayra Pérez-Tapia
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Crossref

Pharmacokinetic Comparability of a Biosimilar Trastuzumab Anticipated from Its Physicochemical and Biological Characterization

BioMed Research International
2015 | Journal article
DOI: /10.1155/2015/874916
Source: Self-asserted source
Emilio Medina-Rivero

Physicochemical and Biological Characterization of a Biosimilar Trastuzumab

BioMed Research International
2015 | Journal article
DOI: 10.1155/2015/427235
Contributors: Carlos A. López-Morales; Mariana P. Miranda-Hernández; L. Carmina Juárez-Bayardo; Nancy D. Ramírez-Ibáñez; Alexis J. Romero-Díaz; Nelly Piña-Lara; Víctor R. Campos-García; Néstor O. Pérez; Luis F. Flores-Ortiz; Emilio Medina-Rivero
Source: check_circle
Crossref

Structural and functional characterization of a recombinant leucine aminopeptidase

2015 | Journal article
DOI:

10.1016/j.molcatb.2014.12.013

EID:

2-s2.0-84922322260
Contributors: Hernández-Moreno, A.V.; Perdomo-Abúndez, F.C.; Pérez-Medina Martínez, V.; Luna-Bárcenas, G.; Villaseñor-Ortega, F.; Pérez, N.O.; López-Morales, C.A.; Flores-Ortiz, L.F.; Medina-Rivero, E.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier
grade
Preferred source (of 2)‎

Swine Dialyzable Spleen Extract as Antiviral Prophylaxis

JOURNAL OF MEDICINAL FOOD
2015 | Journal article
DOI: DOI: 10.1089/jmf.2014.0176
Source: Self-asserted source
Emilio Medina-Rivero

Validation of three viable-cell counting methods: Manual, semi-automated, and automated

Biotechnology Reports
2015-09 | Journal article
DOI: 10.1016/j.btre.2015.04.004
Contributors: Daniela Cadena-Herrera; Joshua E. Esparza-De Lara; Nancy D. Ramírez-Ibañez; Carlos A. López-Morales; Néstor O. Pérez; Luis F. Flores-Ortiz; Emilio Medina-Rivero
Source: check_circle
Crossref

Batch-to-batch reproducibility of Transferon™

2014 | Journal article
DOI:

10.1016/j.jpba.2013.09.004

EID:

2-s2.0-84885070260
Contributors: Medina-Rivero, E.; Merchand-Reyes, G.; Pavón, L.; Vázquez-Leyva, S.; Pérez-Sánchez, G.; Salinas-Jazmín, N.; Estrada-Parra, S.; Velasco-Velázquez, M.; Pérez-Tapia, S.M.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier

Physicochemical properties of Rituximab

2014 | Journal article
DOI:

10.1080/10826076.2013.794738

EID:

2-s2.0-84896134428
Contributors: Flores-Ortiz, L.F.; Campos-García, V.R.; Perdomo-Abúndez, F.C.; Pérez, N.O.; Medina-Rivero, E.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier

Comparability of a Three-Dimensional Structure in Biopharmaceuticals Using Spectroscopic Methods

Journal of Analytical Methods in Chemistry
2014-05-22 | Journal article
DOI:

http://dx.doi.org/10.1155/2014/950598
Contributors: Emilio Medina-Rivero
Source: Self-asserted source
Emilio Medina-Rivero
grade
Preferred source (of 3)‎

Analysis of recombinant monoclonal antibodies by capillary zone electrophoresis

2013 | Journal article
DOI:

10.1002/elps.201200575

EID:

2-s2.0-84876335259
Contributors: Espinosa- de la Garza, C.E.; Perdomo-Abúndez, F.C.; Padilla-Calderón, J.; Uribe-Wiechers, J.M.; Pérez, N.O.; Flores-Ortiz, L.F.; Medina-Rivero, E.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier

Capillary gel electrophoresis for the quantification and purity determination of recombinant proteins in inclusion bodies

2013 | Journal article
DOI:

10.1002/elps.201300232

EID:

2-s2.0-84884207467
Contributors: Espinosa-de la Garza, C.E.; Perdomo-Abúndez, F.C.; Campos-García, V.R.; Pérez, N.O.; Flores-Ortiz, L.F.; Medina-Rivero, E.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier

Kinetics and Conformational stability studies of recombinant leucine aminopeptidase

International Journal od Biological Macromolecules
2013-12-22 | Journal article
DOI:

10.1016/j.ijbiomac.2013.12.023
Contributors: Emilio Medina-Rivero
Source: Self-asserted source
Emilio Medina-Rivero
grade
Preferred source (of 2)‎

High-level production of a recombinant Vibrio proteolyticus leucine aminopeptidase and its use for N-terminal methionine excision from interferon alpha-2b

2011 | Journal article
DOI:

10.1016/j.procbio.2011.06.015

EID:

2-s2.0-80051551805
Contributors: Pérez-Sánchez, G.; Leal-Guadarrama, L.I.; Trelles, I.; Pérez, N.O.; Medina-Rivero, E.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier

Phthalates and bisphenols migration in Mexican food cans and plastic food containers

2011 | Journal article
DOI:

10.1007/s00128-011-0266-3

EID:

2-s2.0-79956004537
Contributors: González-Castro, M.I.; Olea-Serrano, M.F.; Rivas-Velasco, A.M.; Medina-Rivero, E.; Ordoñez-Acevedo, L.G.; De León-Rodríguez, A.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier

Quantification of recombinant human EPO by Reverse Phase Liquid Chromatography Ultra-Resolution | Cuantificación de EPO humana recombinante por Fase Reversa-Cromatografía Líquida de Ultra Resolución

2011 | Journal article
EID:

2-s2.0-84867671773
Contributors: Emilio Medina, R.; Carolina Ortiz, E.; Eduardo González, R.; Néstor, O.; Pérez, R.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier

Interferon-α 2b quantification in inclusion bodies using Reversed Phase-Ultra Performance Liquid Chromatography (RP-UPLC)

2010 | Journal article
DOI:

10.1016/j.jchromb.2010.02.016

EID:

2-s2.0-77950242026
Contributors: Cueto-Rojas, H.F.; Pérez, N.O.; Pérez-Sánchez, G.; Ocampo-Juárez, I.; Medina-Rivero, E.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier

Determination of tween-20 in AgsHB through a spectrophotometric method | Determinación de tween-20 en AgsHB por un método espectrofotométrico

2008 | Journal article
EID:

2-s2.0-46749104563
Contributors: Medina Rivero, E.; López M., C.A.; Pérez R., N.O.; Ferlan, I.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier

Optimization of human interferon gamma production in Escherichia coli by response surface methodology

2008 | Journal article
DOI:

10.1007/s12257-007-0126-5

EID:

2-s2.0-40549087966
Contributors: Balderas Hernández, V.E.; Paz Maldonado, L.M.T.; Rivero, E.M.; Barba de la Rosa, A.P.; Ordoñez Acevedo, L.G.; Rodríguez, A. De L.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier

Periplasmic expression and recovery of human interferon gamma in Escherichia coli

2008 | Journal article
DOI:

10.1016/j.pep.2008.01.019

EID:

2-s2.0-40949143539
Contributors: Balderas Hernández, V.E.; Paz Maldonado, L.M.T.; Medina Rivero, E.; Barba de la Rosa, A.P.; Jiménez-Bremont, J.F.; Ordoñez Acevedo, L.G.; De León Rodríguez, A.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier

Modified penicillin acylase signal peptide allows the periplasmic production of soluble human interferon-γ but not of soluble human interleukin-2 by the Tat pathway in Escherichia coli

2007 | Journal article
DOI:

10.1007/s10529-007-9395-5

EID:

2-s2.0-34547627639
Contributors: Medina-Rivero, E.; Balderas-Hernández, V.E.; Ordoñez-Acevedo, L.G.; Paz-Maldonado, L.M.T.; Barba-De La Rosa, A.P.; De León-Rodríguez, A.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier

Optimization of culture conditions for a synthetic gene expression in Escherichia coli using response surface methodology: The case of human interferon beta

2007 | Journal article
DOI:

10.1016/j.bioeng.2006.10.001

EID:

2-s2.0-34249332439
Contributors: Maldonado, L.M.T.P.; Hernández, V.E.B.; Rivero, E.M.; Barba de la Rosa, A.P.; Flores, J.L.F.; Acevedo, L.G.O.; De León Rodríguez, A.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier

Production of penicillin acylase by a recombinant Escherichia coli using cheese whey as substrate and inducer

2006 | Journal article
DOI:

10.1016/j.bioeng.2006.09.003

EID:

2-s2.0-33751204743
Contributors: De León-Rodríguez, A.; Rivera-Pastrana, D.; Medina-Rivero, E.; Flores-Flores, J.L.; Estrada-Baltazar, A.; Ordóñez-Acevedo, L.G.; de la Rosa, A.P.B.
Source: Self-asserted source
Emilio Medina-Rivero via Scopus - Elsevier
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