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City University of Hong Kong: HK, HK

Employment
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City University of Hong Kong

Works (45)

Targeting TUBB2B inhibits triple-negative breast cancer growth and brain-metastatic colonization

Journal of Experimental and Clinical Cancer Research
2025-02-17 | Journal article | Author
SOURCE-WORK-ID:

497c0157-4296-4f1f-9c7d-36b813c61b63

EID:

2-s2.0-85218416827

Contributors: Qingling HE; Jianyang Hu; Fung-Yin Ngo; Huiqi ZHANG; Lin He; Hao Huang; Tan Wu; Yilin PAN; Zihan YANG; Yuanyuan Jiang et al.
Source: check_circle
City University of Hong Kong

TNA-Mediated Antisense Strategy to Knockdown Akt Genes for Triple-Negative Breast Cancer Therapy

Small Methods
2024-11-20 | Journal article | Author
SOURCE-WORK-ID:

af9b8b8b-bbbd-4ec1-a25b-d4e1901596f1

EID:

2-s2.0-85193802518

EID:

2-s2.0-85193802518

WOSUID:

001230461800001

Contributors: Pan Li; Shixue Zheng; Hoi Man LEUNG; Ling Sum Liu; Tristan Juin Han Chang; Alishba MARYAM; Fei Wang; Yuet Ming Rebecca CHIN; Pik Kwan Lo
Source: check_circle
City University of Hong Kong

FOSL1 is a key regulator of a super-enhancer driving TCOF1 expression in triple-negative breast cancer

Epigenetics and Chromatin
2024-11-10 | Journal article | Author
SOURCE-WORK-ID:

97373fc3-baca-4e12-969f-de293b12d7eb

EID:

2-s2.0-85209475099

WOSUID:

001352395100001

Contributors: Qingling HE; Jianyang Hu; Hao Huang; Tan Wu; Wenxiu LI; Saravanan Ramakrishnan; Yilin PAN; Kui Ming CHAN; Liang ZHANG; Mengsu Yang et al.
Source: check_circle
City University of Hong Kong

Distinguishing high-metastasis-potential circulating tumor cells through fluidic shear stress in a bloodstream-like microfluidic circulatory system

Oncogene
2024-07-19 | Journal article | Author
SOURCE-WORK-ID:

2d2fbf74-a8f8-4114-9088-cb51cbf1a4f4

EID:

2-s2.0-85195469880

WOSUID:

001242790100002

Contributors: Wenxiu LI; Zhengjun Guo; Zhihang Zhou; Zhengdong ZHOU; Huimin He; Jiayu Sun; Xiaoyu Zhou; Yuet Ming Rebecca CHIN; Liang ZHANG; Mengsu Yang
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City University of Hong Kong

Light-Activated Nanodiamond-Based Drug Delivery Systems for Spatiotemporal Release of Antisense Oligonucleotides

Bioconjugate Chemistry
2024-05-15 | Journal article | Author
SOURCE-WORK-ID:

36dff603-c639-4130-8eb8-6610f6e3c191

EID:

2-s2.0-85191845796

WOSUID:

001226239800001

Contributors: Hoi Man LEUNG; Ling Sum Liu; Yuzhen CAI; Xinru Li; Yizhi HUANG; Hoi Ching Chu; Yuet Ming Rebecca CHIN; Pik Kwan Lo
Source: check_circle
City University of Hong Kong

An integrated and multi-functional droplet-based microfluidic platform for digital DNA amplification

Biosensors and Bioelectronics
2024-02-15 | Journal article | Author
SOURCE-WORK-ID:

52a7861d-6e8c-4e45-82ba-eb9746e50d00

EID:

2-s2.0-85181395339

WOSUID:

001127955900001

Contributors: Yuan Wang; Xiaoyu Zhou; Zihan YANG; Tao Xu; Huayang Fu; Chi-Chun Fong; Jiayu Sun; Yuet Ming Rebecca CHIN; Liang ZHANG; Xinyuan Guan et al.
Source: check_circle
City University of Hong Kong

Super-enhancer-driven cancer stemness and metastasis genes in triple-negative breast cancer

Keystone Symposia : Metastasis, Vancouver, Canada, 7/05/23
2023-05 | Conference abstract | Author
SOURCE-WORK-ID:

2cfba474-84b2-4752-a2ac-5dd7efaedfae

Contributors: Jianyang Hu; Qingling HE; Hao Huang; Xin Wang; Yuet Ming Rebecca CHIN
Source: check_circle
City University of Hong Kong

High Throughput Confined Migration Microfluidic Device for Drug Screening

Small
2023-04-19 | Journal article | Author
SOURCE-WORK-ID:

2cd7daa1-2462-4d72-bce3-426fb42a4c12

EID:

2-s2.0-85146275988

WOSUID:

000912637200001

Contributors: Zihan YANG; Zhihang Zhou; Tongxu SI; Zhengdong ZHOU; Li Zhou; Yuet Ming Rebecca CHIN; Liang Zhang; Xinyuan Guan; Mengsu Yang
Source: check_circle
City University of Hong Kong

Akt3 promotes cancer stemness in triple-negative breast cancer through YB1-Snail/Slug signaling axis

Genes & Diseases
2023-03 | Other | Author
SOURCE-WORK-ID:

6bcc3dcf-82fe-442b-b39c-2abd7d3bc0a1

EID:

2-s2.0-85138107206

WOSUID:

000996075000001

Contributors: Ye TIAN; Jiang Li; Tsz Chung Cheung; Vincent Tam; C. Geoffrey Lau; Xin Wang; Yuet Ming Rebecca CHIN
Source: check_circle
City University of Hong Kong

3D Biomimetic Models to Reconstitute Tumor Microenvironment In Vitro

Advanced Healthcare Materials
2023-03-14 | Journal article | Author
SOURCE-WORK-ID:

832fa003-f5f6-4070-8d9f-41d69e1cd47c

EID:

2-s2.0-85151290374

WOSUID:

000983963200001

Contributors: Wenxiu LI; Zhihang Zhou; Xiaoyu Zhou; Bee Luan Khoo; Renardi GUNAWAN; Yuet Ming Rebecca CHIN; Liang ZHANG; Changqing Yi; Xinyuan Guan; Mengsu Yang
Source: check_circle
City University of Hong Kong

Upregulation of Receptor Tyrosine Kinase Activity and Stemness as Resistance Mechanisms to Akt Inhibitors in Breast Cancer

Cancers
2022-10-13 | Journal article | Author
SOURCE-WORK-ID:

7f7db514-5044-4f67-9823-749089c49808

EID:

2-s2.0-85140639329

WOSUID:

000874205400001

Contributors: Tiffany Tsang; Qingling HE; Emily B. Cohen; Casey Stottrup; Evan C. Lien; Huiqi ZHANG; C. Geoffrey Lau; Yuet Ming Rebecca CHIN
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

Cellular uptake, tissue penetration, biodistribution, and biosafety of threose nucleic acids

Materials Today Bio
2022-06 | Journal article | Author
SOURCE-WORK-ID:

935df773-2483-445d-b466-45fa5aa9b70b

EID:

2-s2.0-85130525048

WOSUID:

000829470700005

Contributors: Fei Wang; Ling Sum Liu; Pan Li; Cia Hin Lau; Hoi Man LEUNG; Yuet Ming Rebecca CHIN; Chung TIN; Pik Kwan Lo
Source: check_circle
City University of Hong Kong

TCOF1 upregulation in triple-negative breast cancer promotes stemness and tumour growth and correlates with poor prognosis

British Journal of Cancer
2022-01-01 | Journal article | Author
SOURCE-WORK-ID:

6c1803e2-64b8-4063-b83f-956212820337

EID:

2-s2.0-85118301344

WOSUID:

000712942700003

Contributors: Jianyang Hu; Yuni Lai; Hao Huang; Saravanan Ramakrishnan; Yilin PAN; Victor W. S. Ma; Wah Cheuk; Grace Y. K. So; Qingling HE; C. Geoffrey Lau et al.
Source: check_circle
City University of Hong Kong

Cancer stem cells

Annals of the New York Academy of Sciences
2021-12 | Journal article | Author
SOURCE-WORK-ID:

293ad7ce-1792-4b96-94a0-1ea2a25e02e6

EID:

2-s2.0-85121785272

WOSUID:

000723830500001

Contributors: Jennifer Cable; Duanqing Pei; Lola M. Reid; Xin Wei Wang; Sonam Bhatia; Panagiotis Karras; Jan Joseph Melenhorst; Markus Grompe; Justin D. Lathia; Erwei Song et al.
Source: check_circle
City University of Hong Kong

Guide RNA Molecule And Method for Treating Cancer

2021-12-28 | Patent
SOURCE-WORK-ID:

9449b60d-0ef6-4dd9-85d0-84f196d323b2

PAT:

US11,207,425

Contributors: Yuet Ming Rebecca CHIN; Xin Wang; Jianyang HU
Source: check_circle
City University of Hong Kong

ANLN Enhances Triple-Negative Breast Cancer Stemness Through TWIST1 and BMP2 and Promotes its Spheroid Growth

Frontiers in Molecular Biosciences
2021-07-01 | Journal article | Author
SOURCE-WORK-ID:

af71de4b-a56f-43e3-b1f1-fb82ca4eb034

EID:

2-s2.0-85110185465

WOSUID:

000673642300001

Contributors: Alishba MARYAM; Yuet Ming Rebecca CHIN
Source: check_circle
City University of Hong Kong

Subtype-dependent heterogeneity of super-enhancers in breast cancer

Precision Oncology: Translating Discovery to the Clinic, 21/06/21
2021-06-21 | Conference poster | Author
SOURCE-WORK-ID:

f42a3729-cdf8-472b-9d4d-b137294111fd

Contributors: Hao Huang; Jianyang Hu; Xin Wang; Yuet Ming Rebecca CHIN
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City University of Hong Kong

Clustering of super-enhancers for characterizing subtype identity in breast cancer

Cancer Stem Cells: Advances in Biology and Clinical Translation, 19/05/21
2021-05-19 | Conference abstract | Author
SOURCE-WORK-ID:

09b1a3d3-48b2-46b8-a58a-28df9702521c

Contributors: Hao Huang; Jianyang Hu; Alishba MARYAM; Xin Wang; Yuet Ming Rebecca CHIN
Source: check_circle
City University of Hong Kong

Defining super-enhancer landscape in triple-negative breast cancer by multiomic profiling

Nature Communications
2021-04-14 | Journal article | Author
SOURCE-WORK-ID:

61baeae4-6d1a-4d18-bcb1-40efa6238119

EID:

2-s2.0-85104328129

WOSUID:

000640561300006

Contributors: Hao Huang; Jianyang Hu; Alishba MARYAM; Qinghua Huang; Yuchen Zhang; Saravanan Ramakrishnan; Jingyu LI; Haiying MA; Victor W. S. Ma; Wah Cheuk et al.
Source: check_circle
City University of Hong Kong

FOXC1 expression is associated with a triple-negative basal-like phenotype in breast cancer

AACR Annual Meeting 2020 II, 22/06/20
2020-06 | Conference abstract | Author
SOURCE-WORK-ID:

673c1adf-4536-4242-87ee-145d9577a016

Contributors: William C. S. Cho; Victor W. S. Ma; Wah CHEUK; Grace Y. K. So; Yuet Ming Rebecca CHIN
Source: check_circle
City University of Hong Kong

Targeting Akt isoform-specific signaling in breast cancer progression

Keystone Symposia: Cancer Metastasis, Florence, Italy, 15/03/19
2019-03-15 | Conference poster | Author
SOURCE-WORK-ID:

198e1048-2e3d-41df-abb2-fb2bd56ff558

Contributors: Tiffany Tsang; Yuet Ming Rebecca CHIN
Source: check_circle
City University of Hong Kong

Resistance mechanisms to Akt inhibitors in breast cancer

Keystone Symposia - Precision Medicine in Cancer, Stockholm, Sweden, 6/05/18
2018-05 | Conference abstract | Author
SOURCE-WORK-ID:

cbf21423-fa69-4343-8158-79d1c6a0b930

Contributors: Yuet Ming Rebecca CHIN
Source: check_circle
City University of Hong Kong

Upregulation of AKT3 confers resistance to the AKT Inhibitor MK2206 in breast cancer

Molecular Cancer Therapeutics
2016-08-01 | Journal article | Author
SOURCE-WORK-ID:

314a08e8-2789-4369-b681-ba5714018708

EID:

2-s2.0-84985995870

Contributors: Casey Stottrup; Tiffany Tsang; Yuet Ming Rebecca CHIN
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt

Molecular Cell
2016-06-16 | Journal article | Author
SOURCE-WORK-ID:

01f240ec-a601-44d3-9bea-6cc06d738319

EID:

2-s2.0-84970023716

Contributors: Jinfang Zhang; Kai Xu; Pengda Liu; Yan Geng; Bin Wang; Wenjian Gan; Jianping Guo; Fei Wu; Yuet Ming Rebecca CHIN; Christian Berrios et al.
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City University of Hong Kong
grade
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Ptdins(3,4,5) P3 -dependent activation of the mTORC2 kinase complex

Cancer Discovery
2015-11 | Journal article | Author
SOURCE-WORK-ID:

d4231060-ff5b-42e1-8390-332c7830fe33

EID:

2-s2.0-84946216201

WOSUID:

000365597400026

Contributors: Pengda Liu; Wenjian Gan; Yuet Ming Rebecca CHIN; Kohei Ogura; Jianping Guo; Jinfang Zhang; Bin Wang; John Blenis; Lewis C. Cantley; Alex Toker et al.
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

PTEN-deficient tumors depend on AKT2 for maintenance and survival

Cancer Discovery
2014-08 | Journal article | Author
SOURCE-WORK-ID:

548cf113-efe4-4855-8dc7-67986292b7f0

EID:

2-s2.0-84905460232

WOSUID:

000343120400028

Contributors: Yuet Ming Rebecca CHIN; Xin Yuan; Steven P. Balk; Alex Toker
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

Akt-ing Up on SRPK1

Molecular Cell
2014-05-08 | Other | Author
SOURCE-WORK-ID:

d7afbab1-8c59-49fe-a96a-2372264328dc

EID:

2-s2.0-84899790149

Contributors: Alex Toker; Yuet Ming Rebecca CHIN
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

Targeting Akt3 signaling in triple-negative breast cancer

Cancer Research
2014-02-01 | Journal article | Author
SOURCE-WORK-ID:

67ef5c2c-010e-4480-9896-f38928b9fdd2

EID:

2-s2.0-84893853376

Contributors: Yuet Ming Rebecca CHIN; Taku Yoshida; Andriy Marusyk; Andrew H. Beck; Kornelia Polyak; Alex Toker
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

RhoB differentially controls akt function in tumor cells and stromal endothelial cells during breast tumorigenesis

Cancer Research
2013-01-01 | Journal article | Author
SOURCE-WORK-ID:

17723483-8150-4d10-b798-47e69bd439e0

EID:

2-s2.0-84871967188

Contributors: Shiva Kazerounian; Damien Gerald; Minzhou Huang; Yuet Ming Rebecca CHIN; Durga Udayakumar; Ningning Zheng; Rebekah K. O'Donnell; Carole Perruzzi; Lee Mangiante; Jacob Pourat et al.
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

Acetylation-dependent regulation of Skp2 function

Cell
2012-07-06 | Journal article | Author
SOURCE-WORK-ID:

ff569c69-9405-4748-8bb2-058c2341375a

EID:

2-s2.0-84863618431

Contributors: Hiroyuki Inuzuka; Daming Gao; Lydia W.S. Finley; Wen Yang; Lixin Wan; Hidefumi Fukushima; Yuet Ming Rebecca CHIN; Bo Zhai; Shavali Shaik; Alan W. Lau et al.
Source: check_circle
City University of Hong Kong
grade
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Akt isoform-specific signaling in breast cancer: Uncovering an anti-migratory role of palladin

Cell Adhesion and Migration
2011 | Journal article
EID:

2-s2.0-79957830916

Contributors: Chin, Y.R.; Toker, A.
Source: Self-asserted source
Yuet Ming Rebecca CHIN via Scopus - Elsevier

NFAT promotes carcinoma invasive migration through glypican-6

Biochemical Journal
2011-11-15 | Journal article | Author
SOURCE-WORK-ID:

32948a2c-1e5a-4b79-8531-c2248f83e65a

EID:

2-s2.0-80054942842

Contributors: Gary K. Yiu; Aura Kaunisto; Yuet Ming Rebecca CHIN; Alex Toker
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

MTOR drives its own activation via SCF βTrCP-dependent degradation of the mTOR inhibitor DEPTOR

Molecular Cell
2011-10-21 | Journal article | Author
SOURCE-WORK-ID:

488759c5-27f3-4183-ac83-f02c04dd513e

EID:

2-s2.0-81855181738

Contributors: Daming Gao; Hiroyuki Inuzuka; Meng-Kwang Marcus Tan; Hidefumi Fukushima; Jason W. Locasale; Pengda Liu; Lixin Wan; Bo Zhai; Yuet Ming Rebecca CHIN; Shavali Shaik et al.
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City University of Hong Kong
grade
Preferred source (of 2)‎

Akt isoform-specific signaling in breast cancer

Cell adhesion & migration
2011-05 | Other | Author
SOURCE-WORK-ID:

18182314-60c3-4e44-afeb-a919a9035385

EID:

2-s2.0-84555191987

Contributors: Yuet Ming Rebecca CHIN; Alex Toker
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

Akt2 regulates expression of the actin-bundling protein palladin

FEBS Letters
2010-12-01 | Journal article | Author
SOURCE-WORK-ID:

f0f8bc2d-3281-48b7-a9e5-eb75e5a600de

EID:

2-s2.0-78649658961

Contributors: Yuet Ming Rebecca CHIN; Alex Toker
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

The Actin-Bundling Protein Palladin Is an Akt1-Specific Substrate that Regulates Breast Cancer Cell Migration

Molecular Cell
2010-05-14 | Journal article | Author
SOURCE-WORK-ID:

0af871e4-16bd-4a5b-85bd-c527d680673d

EID:

2-s2.0-77951962854

Contributors: Yuet Ming Rebecca CHIN; Alex Toker
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

Nature Cell Biology
2009 | Journal article | Author
SOURCE-WORK-ID:

69703ee4-ce80-4a7f-954c-380073ee96fb

EID:

2-s2.0-64049086572

Contributors: Daming Gao; Hiroyuki Inuzuka; Alan Tseng; Yuet Ming Rebecca CHIN; Alex Toker; Wenyi Wei
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma

Cancer Research
2009-08-01 | Journal article | Author
SOURCE-WORK-ID:

adf25b44-2dc1-4e13-aabc-b286995efa3e

EID:

2-s2.0-68049117229

Contributors: Matthew Maurer; Tao Su; Lao H. Saal; Susan Koujak; Benjamin D. Hopkins; Christina R. Barkley; Jiaping Wu; Subhadra Nandula; Bhaskar Dutta; Yuli Xie et al.
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer

Cellular Signalling
2009-04 | Other | Author
SOURCE-WORK-ID:

ce510e3c-c6e2-42db-834a-ef05d61468ee

EID:

2-s2.0-59749095009

Contributors: Yuet Ming Rebecca CHIN; Alex Toker
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

Akt/protein kinase B and glycogen synthase kinase-3β signaling pathway regulates cell migration through the NFAT1 transcription factor

Molecular Cancer Research
2009-03-01 | Journal article | Author
SOURCE-WORK-ID:

ab7d87b0-fa61-47cf-9c2c-572ca117a7a5

EID:

2-s2.0-62549124971

Contributors: Merav Yoeli-Lerner; Yuet Ming Rebecca CHIN; Christopher K. Hansen; Alex Toker
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

Adenovirus RID complex enhances degradation of internalized tumour necrosis factor receptor 1 without affecting its rate of endocytosis

Journal of General Virology
2006-11 | Journal article | Author
SOURCE-WORK-ID:

2762c697-c845-465b-8b7c-762e92836084

EID:

2-s2.0-33750277448

Contributors: Yuet Ming Rebecca CHIN; Marshall S. Horwitz
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

Mechanism for removal of tumor necrosis factor receptor 1 from the cell surface by the adenovirus RIDα/β complex

Journal of Virology
2005-11 | Journal article | Author
SOURCE-WORK-ID:

f684cefc-ad72-4de0-9228-f1657f5bc7ea

EID:

2-s2.0-27144544036

Contributors: Yuet Ming Rebecca CHIN; Marshall S. Horwitz
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

Inhibition of tumor necrosis factor (TNF) signal transduction by the adenovirus group C RID complex involves downregulation of surface levels of TNF receptor 1

Journal of Virology
2004-12 | Journal article | Author
SOURCE-WORK-ID:

729ba0dc-5906-48cb-9768-9de86c28e6d3

EID:

2-s2.0-8744245265

Contributors: Shawn P. Fessler; Yuet Ming Rebecca CHIN; Marshall S. Horwitz
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

High-throughput screening of potential inhibitors for the metabolism of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
2002 | Journal article | Author
SOURCE-WORK-ID:

0f4e7ce9-730b-492a-99b4-3796ce32288a

EID:

2-s2.0-0036162227

Contributors: Shufeng Zhou; Daniel Chiang; Yuet Ming Rebecca CHIN; Philip Kestell; James W. Paxton
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

Effects of anticancer drugs on the metabolism of the anticancer drug 5,6-dimethylxanthenone-4-acetic (DMXAA) by human liver microsomes

British Journal of Clinical Pharmacology
2001 | Journal article | Author
SOURCE-WORK-ID:

b8e4a830-0749-47f6-80ba-6f1b4927b9a8

EID:

2-s2.0-0034836915

Contributors: Shufeng Zhou; Yuet Ming Rebecca CHIN; Philip Kestell; Malcolm D. Tingle; James W. Paxton
Source: check_circle
City University of Hong Kong
grade
Preferred source (of 2)‎

Peer review (2 reviews for 1 publication/grant)

Review activity for Developmental cell. (2)