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Scopus Author ID: 6507901873

Keywords

eQTL, expression Quantitative Trait Loci, transcriptome, sex differences, women's health, genome-wide association studies, statistical genetics, genomics, gene-environment interactions, population genetics, genetic variation

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Funding (1)

The genetic basis of cross-tissue protein expression variability in humans

2014-06-01 to 2017-03-31 | Grant
National Human Genome Research Institute (Bethesda, US)
URL: https://grants.uberresearch.com/100000051/U01HG007598/The-genetic-basis-of-cross-tissue-protein-expression-variability-in-humans
GRANT_NUMBER: U01HG007598
Source: Self-asserted source
Barbara Stranger via DimensionsWizard

Works (50 of 70)

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Sex differences in the molecular profile of adult diffuse glioma are shaped by IDH status and tumor microenvironment

Neuro-Oncology
2025-02-10 | Journal article
DOI: 10.1093/neuonc/noae207
Contributors: Yingbo Huang; Yuting Shan; Weijie Zhang; Christina Printzis; Lorenzo Pesce; Danielle Stover; Catherine Stanhope; Barbara E Stranger; Rong Stephanie Huang
Source: check_circle
Crossref

Uncovering hidden gene-trait patterns through biclustering analysis of the UK Biobank

2024-11-11 | Preprint
DOI: 10.1101/2024.11.08.622657
Contributors: Milton Pividori; Suraju Sadeeq; Arjun Krishnan; Barbara E. Stranger; Christopher R. Gignoux
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Crossref

Quality control and analytic best practices for testing genetic models of sex differences in large populations

Cell
2023-05 | Journal article
DOI: 10.1016/j.cell.2023.04.014
Contributors: Ekaterina A. Khramtsova; Melissa A. Wilson; Joanna Martin; Stacey J. Winham; Karen Y. He; Lea K. Davis; Barbara E. Stranger
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Crossref

Toward a deeper understanding of gene-by-sex interaction models

Cell Genomics
2023-05 | Journal article
DOI: 10.1016/j.xgen.2023.100324
Contributors: Ekaterina A. Khramtsova; Stacey J. Winham; Lea K. Davis; Barbara E. Stranger; Melissa A. Wilson
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Crossref

Deciphering genetic causes for sex differences in human health through drug metabolism and transporter genes

Nature Communications
2023-01-12 | Journal article
DOI: 10.1038/s41467-023-35808-6
Contributors: Yingbo Huang; Yuting Shan; Weijie Zhang; Adam M. Lee; Feng Li; Barbara E. Stranger; R. Stephanie Huang
Source: check_circle
Crossref

Systematic evaluation of transcriptomics-based deconvolution methods and references using thousands of clinical samples

2021-03-10 | Other
DOI: 10.1101/2021.03.09.434660
Contributors: Brian B. Nadel; Meritxell Oliva; Benjamin L. Shou; Keith Mitchell; Feiyang Ma; Dennis J. Montoya; Alice Mouton; Sarah Kim-Hellmuth; Barbara E. Stranger; Matteo Pellegrini et al.
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Crossref

ImmGen report: sexual dimorphism in the immune system transcriptome

Nature Communications
2019-09-20 | Journal article
DOI: 10.1038/s41467-019-12348-6
Contributors: Shani Talia Gal-Oz; Barbara Maier; Hideyuki Yoshida; Kumba Seddu; Nitzan Elbaz; Charles Czysz; Or Zuk; Barbara E. Stranger; Hadas Ner-Gaon; Tal Shay
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Crossref

The role of sex in the genomics of human complex traits

Nature Reviews Genetics
2019-03-23 | Journal article
DOI: 10.1038/s41576-018-0083-1
Contributors: Ekaterina A. Khramtsova; Lea K. Davis; Barbara E. Stranger
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Crossref

Neuroblastoma survivors are at increased risk for second malignancies: A report from the International Neuroblastoma Risk Group Project

European Journal of Cancer
2017 | Journal article
DOI: 10.1016/j.ejca.2016.11.022
EID:

2-s2.0-85007143689
Contributors: Applebaum, M.A.; Vaksman, Z.; Lee, S.M.; Hungate, E.A.; Henderson, T.O.; London, W.B.; Pinto, N.; Volchenboum, S.L.; Park, J.R.; Naranjo, A. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Sex differences in the genetic architecture of obsessive-compulsive disorder

2017-11-21 | Other
DOI: 10.1101/219170
Contributors: Ekaterina A. Khramtsova; Raphael Heldman; Eske M. Derks; Dongmei Yu; Lea K. Davis; Barbara E. Stranger
Source: check_circle
Crossref

Enhancing GTEx by bridging the gaps between genotype, gene expression, and disease

Nature Genetics
2017-10-11 | Journal article
DOI: 10.1038/ng.3969
Contributors: Barbara E Stranger; Lori E Brigham; Richard Hasz; Marcus Hunter; Christopher Johns; Mark Johnson; Gene Kopen; William F Leinweber; John T Lonsdale; Alisa McDonald et al.
Source: check_circle
Crossref

Imputing Gene Expression in Uncollected Tissues Within and beyond GTEx

American Journal of Human Genetics
2016 | Journal article
DOI: 10.1016/j.ajhg.2016.02.020
EID:

2-s2.0-84962081673
Contributors: Wang, J.; Gamazon, E.R.; Pierce, B.L.; Stranger, B.E.; Im, H.K.; Gibbons, R.D.; Cox, N.J.; Nicolae, D.L.; Chen, L.S.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients

Oncotarget
2016 | Journal article
DOI: 10.18632/oncotarget.12713
EID:

2-s2.0-84998723923
Contributors: Applebaum, M.A.; Jha, A.R.; Kao, C.; Hernandez, K.M.; DeWane, G.; Salwen, H.R.; Chlenski, A.; Dobratic, M.; Mariani, C.J.; Godley, L.A. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Accurate and Fast Multiple-Testing Correction in eQTL Studies

American Journal of Human Genetics
2015 | Journal article
DOI: 10.1016/j.ajhg.2015.04.012
EID:

2-s2.0-84930024854
Contributors: Sul, J.H.; Raj, T.; de Jong, S.; de Bakker, P.I.W.; Raychaudhuri, S.; Ophoff, R.A.; Stranger, B.E.; Eskin, E.; Han, B.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Design and implementation of the international genetics and translational research in transplantation network

Transplantation
2015 | Journal article
DOI: 10.1097/TP.0000000000000913
EID:

2-s2.0-84945968895
Contributors: Keating, B.J.; Van Setten, J.; Jacobson, P.A.; Holmes, M.V.; Verma, S.S.; Chandrupatla, H.R.; Nair, N.; Gao, H.; Li, Y.R.; Chang, B.-L. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci

American Journal of Human Genetics
2015 | Journal article
DOI: 10.1016/j.ajhg.2015.05.016
EID:

2-s2.0-84937424402
Contributors: Trynka, G.; Westra, H.-J.; Slowikowski, K.; Hu, X.; Xu, H.; Stranger, B.E.; Klein, R.J.; Han, B.; Raychaudhuri, S.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Expression quantitative trait loci information improves predictive modeling of disease relevance of non-coding genetic variation

PLoS ONE
2015 | Journal article
DOI: 10.1371/journal.pone.0140758
EID:

2-s2.0-84948974979
Contributors: Croteau-Chonka, D.C.; Rogers, A.J.; Raj, T.; McGeachie, M.J.; Qiu, W.; Ziniti, J.P.; Stubbs, B.J.; Liang, L.; Martinez, F.D.; Strunk, R.C. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Human HLA-G+ extravillous trophoblasts: Immune-activating cells that interact with decidual leukocytes

Proceedings of the National Academy of Sciences of the United States of America
2015 | Journal article
DOI: 10.1073/pnas.1507977112
EID:

2-s2.0-84931281669
Contributors: Tilburgs, T.; Crespo, A.C.; Van Der Zwan, A.; Rybalov, B.; Raj, T.; Stranger, B.; Gardner, L.; Moffett, A.; Strominger, J.L.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

ImmVar project: Insights and design considerations for future studies of "healthy" immune variation

Seminars in Immunology
2015 | Journal article
DOI: 10.1016/j.smim.2015.03.003
EID:

2-s2.0-84928695024
Contributors: De Jager, P.L.; Hacohen, N.; Mathis, D.; Regev, A.; Stranger, B.E.; Benoist, C.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

The impact of human copy number variation on gene expression

Briefings in Functional Genomics
2015 | Journal article
DOI: 10.1093/bfgp/elv017
EID:

2-s2.0-84942318569
Contributors: Gamazon, E.R.; Stranger, B.E.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

The transcriptional landscape of age in human peripheral blood

Nature Communications
2015 | Journal article
DOI: 10.1038/ncomms9570
EID:

2-s2.0-84945143930
Contributors: Peters, M.J.; Joehanes, R.; Pilling, L.C.; Schurmann, C.; Conneely, K.N.; Powell, J.; Reinmaa, E.; Sutphin, G.L.; Zhernakova, A.; Schramm, K. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

CD33: Increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility

Human Molecular Genetics
2014 | Journal article
DOI: 10.1093/hmg/ddt666
EID:

2-s2.0-84898770218
Contributors: Raj, T.; Ryan, K.J.; Replogle, J.M.; Chibnik, L.B.; Rosenkrantz, L.; Tang, A.; Rothamel, K.; Stranger, B.E.; Bennett, D.A.; Evans, D.A. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Common genetic variants modulate pathogen-sensing responses in human dendritic cells

Science
2014 | Journal article
DOI: 10.1126/science.1246980
EID:

2-s2.0-84896759364
Contributors: Lee, M.N.; Ye, C.; Villani, A.-C.; Raj, T.; Li, W.; Eisenhaure, T.M.; Imboywa, S.H.; Chipendo, P.I.; Ran, F.A.; Slowikowski, K. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Expression QTL-based analyses reveal candidate causal genes and loci across five tumor types

Human molecular genetics
2014 | Journal article
DOI: 10.1093/hmg/ddu228
EID:

2-s2.0-84964315018
Contributors: Li, Q.; Stram, A.; Chen, C.; Kar, S.; Gayther, S.; Pharoah, P.; Haiman, C.; Stranger, B.; Kraft, P.; Freedman, M.L.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Nature
2014 | Journal article
DOI: 10.1038/nature12873
EID:

2-s2.0-84894288992
Contributors: Okada, Y.; Wu, D.; Trynka, G.; Raj, T.; Terao, C.; Ikari, K.; Kochi, Y.; Ohmura, K.; Suzuki, A.; Yoshida, S. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Genomics of alternative splicing: Evolution, development and pathophysiology

Human Genetics
2014 | Journal article
DOI: 10.1007/s00439-013-1411-3
EID:

2-s2.0-84901244730
Contributors: Gamazon, E.R.; Stranger, B.E.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Interindividual variation in human T regulatory cells

Proceedings of the National Academy of Sciences of the United States of America
2014 | Journal article
DOI: 10.1073/pnas.1401343111
EID:

2-s2.0-84896970908
Contributors: Ferraro, A.; D'Alise, A.M.; Raj, T.; Asinovski, N.; Phillips, R.; Ergun, A.; Replogle, J.M.; Bernier, A.; Laffel, L.; Stranger, B.E. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Intersection of population variation and autoimmunity genetics in human T cell activation

Science
2014 | Journal article
DOI: 10.1126/science.1254665
EID:

2-s2.0-84907202723
Contributors: Ye, C.J.; Feng, T.; Kwon, H.-K.; Raj, T.; Wilson, M.T.; Asinovski, N.; McCabe, C.; Lee, M.H.; Frohlich, I.; Paik, H.-I. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes

Science
2014 | Journal article
DOI: 10.1126/science.1249547
EID:

2-s2.0-84900338300
Contributors: Raj, T.; Rothamel, K.; Mostafavi, S.; Ye, C.; Lee, M.N.; Replogle, J.M.; Feng, T.; Lee, M.; Asinovski, N.; Frohlich, I. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4<sup>+</sup> Effector Memory T Cells

PLoS Genetics
2014 | Journal article
DOI: 10.1371/journal.pgen.1004404
EID:

2-s2.0-84903457544
Contributors: Hu, X.; Kim, H.; Raj, T.; Brennan, P.J.; Trynka, G.; Teslovich, N.; Slowikowski, K.; Chen, W.-M.; Onengut, S.; Baecher-Allan, C. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Balancing Selection on a Regulatory Region Exhibiting Ancient Variation That Predates Human-Neandertal Divergence

PLoS Genetics
2013 | Journal article
DOI: 10.1371/journal.pgen.1003404
EID:

2-s2.0-84876836372
Contributors: Gokcumen, O.; Zhu, Q.; Mulder, L.C.F.; Iskow, R.C.; Austermann, C.; Scharer, C.D.; Raj, T.; Boss, J.M.; Sunyaev, S.; Price, A. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Chromatin marks identify critical cell types for fine mapping complex trait variants

Nature Genetics
2013 | Journal article
DOI: 10.1038/ng.2504
EID:

2-s2.0-84873086126
Contributors: Trynka, G.; Sandor, C.; Han, B.; Xu, H.; Stranger, B.E.; Liu, X.S.; Raychaudhuri, S.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Common risk alleles for inflammatory diseases are targets of recent positive selection

American Journal of Human Genetics
2013 | Journal article
DOI: 10.1016/j.ajhg.2013.03.001
EID:

2-s2.0-84875952705
Contributors: Raj, T.; Kuchroo, M.; Replogle, J.M.; Raychaudhuri, S.; Stranger, B.E.; De Jager, P.L.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects

PLoS Genetics
2013 | Journal article
DOI: 10.1371/journal.pgen.1003926
EID:

2-s2.0-84888231843
Contributors: Patsopoulos, N.A.; Barcellos, L.F.; Hintzen, R.Q.; Schaefer, C.; van Duijn, C.M.; Noble, J.A.; Raj, T.; Gourraud, P.-A.; Stranger, B.E.; Oksenberg, J. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Genetics of human gene expression

Current Opinion in Genetics and Development
2013 | Journal article
DOI: 10.1016/j.gde.2013.10.004
EID:

2-s2.0-84889581286
Contributors: Stranger, B.E.; Raj, T.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis

PLoS Genetics
2013 | Journal article
DOI: 10.1371/journal.pgen.1003394
EID:

2-s2.0-84875993860
Contributors: Cui, J.; Stahl, E.A.; Saevarsdottir, S.; Miceli, C.; Diogo, D.; Trynka, G.; Raj, T.; Mirkov, M.U.; Canhao, H.; Ikari, K. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Integrative eQTL-based analyses reveal the biology of breast cancer risk loci

Cell
2013 | Journal article
DOI: 10.1016/j.cell.2012.12.034
EID:

2-s2.0-84873288058
Contributors: Li, Q.; Seo, J.-H.; Stranger, B.; McKenna, A.; Pe'Er, I.; Laframboise, T.; Brown, M.; Tyekucheva, S.; Freedman, M.L.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Alzheimer disease susceptibility loci: Evidence for a protein network under natural selection

American Journal of Human Genetics
2012 | Journal article
DOI: 10.1016/j.ajhg.2012.02.022
EID:

2-s2.0-84859499759
Contributors: Raj, T.; Shulman, J.M.; Keenan, B.T.; Chibnik, L.B.; Evans, D.A.; Bennett, D.A.; Stranger, B.E.; De Jager, P.L.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Analysis of case-control association studies with known risk variants

Bioinformatics
2012 | Journal article
DOI: 10.1093/bioinformatics/bts259
EID:

2-s2.0-84864026028
Contributors: Zaitlen, N.; Paşaniuc, B.; Patterson, N.; Pollack, S.; Voight, B.; Groop, L.; Altshuler, D.; Henderson, B.E.; Kolonel, L.N.; Marchand, L.L. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Coordinating GWAS results with gene expression in a systems immunologic paradigm in autoimmunity

Current Opinion in Immunology
2012 | Journal article
DOI: 10.1016/j.coi.2012.09.002
EID:

2-s2.0-84867748091
Contributors: Stranger, B.E.; De Jager, P.L.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Extensive genetic diversity and substructuring among zebrafish strains revealed through copy number variant analysis

Proceedings of the National Academy of Sciences of the United States of America
2012 | Journal article
DOI: 10.1073/pnas.1112163109
EID:

2-s2.0-84862907760
Contributors: Brown, K.H.; Dobrinski, K.P.; Lee, A.S.; Gokcumen, O.; Mills, R.E.; Shi, X.; Chong, W.W.S.; Chen, J.Y.H.; Yoo, P.; David, S. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Patterns of Cis regulatory variation in diverse human populations

PLoS Genetics
2012 | Journal article
DOI: 10.1371/journal.pgen.1002639
EID:

2-s2.0-84860596557
Contributors: Stranger, B.E.; Montgomery, S.B.; Dimas, A.S.; Parts, L.; Stegle, O.; Ingle, C.E.; Sekowska, M.; Smith, G.D.; Evans, D.; Gutierrez-Arcelus, M. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Sex-biased genetic effects on gene regulation in humans

Genome Research
2012 | Journal article
DOI: 10.1101/gr.134981.111
EID:

2-s2.0-84870516488
Contributors: Dimas, A.S.; Nica, A.C.; Montgomery, S.B.; Stranger, B.E.; Raj, T.; Buil, A.; Giger, T.; Lappalainen, T.; Gutierrez-Arcelus, M.; McCarthy, M.I. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Systems and genome-wide approaches unite to provide a route to personalized medicine

Genome Medicine
2012 | Journal article
DOI: 10.1186/gm328
EID:

2-s2.0-84859037123
Contributors: Stranger, B.E.; Björkegren, J.; Dolan, M.E.; Ritchie, M.D.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Progress and promise of genome-wide association studies for human complex trait genetics

Genetics
2011 | Journal article
DOI: 10.1534/genetics.110.120907
EID:

2-s2.0-79951521421
Contributors: Stranger, B.E.; Stahl, E.A.; Raj, T.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations

PLoS Genetics
2010 | Journal article
DOI: 10.1371/journal.pgen.1000895
EID:

2-s2.0-77952367694
Contributors: Nica, A.C.; Montgomery, S.B.; Dimas, A.S.; Stranger, B.E.; Beazley, C.; Barroso, I.; Dermitzakis, E.T.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Genevar: A database and Java application for the analysis and visualization of SNP-gene associations in eQTL studies

Bioinformatics
2010 | Journal article
DOI: 10.1093/bioinformatics/btq452
EID:

2-s2.0-77957232748
Contributors: Yang, T.-P.; Beazley, C.; Montgomery, S.B.; Dimas, A.S.; Gutierrez-Arcelus, M.; Stranger, B.E.; Deloukas, P.; Dermitzakis, E.T.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci

Genes and Immunity
2010 | Journal article
DOI: 10.1038/gene.2010.28
EID:

2-s2.0-77954886757
Contributors: Esposito, F.; Patsopoulos, N.A.; Cepok, S.; Kockum, I.; Leppä, V.; Booth, D.R.; Heard, R.N.; Stewart, G.J.; Cox, M.; Scott, R.J. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease

Human Molecular Genetics
2010 | Journal article
DOI: 10.1093/hmg/ddq041
EID:

2-s2.0-77952515610
Contributors: Prescott, N.J.; Dominy, K.M.; Kubo, M.; Lewis, C.M.; Fisher, S.A.; Redon, R.; Huang, N.; Stranger, B.E.; Blaszczyk, K.; Hudspith, B. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier

Common regulatory variation impacts gene expression in a cell type-dependent manner

Science
2009 | Journal article
DOI: 10.1126/science.1174148
EID:

2-s2.0-69949176863
Contributors: Dimas, A.S.; Deutsch, S.; Stranger, B.E.; Montgomery, S.B.; Borel, C.; Attar-Cohen, H.; Ingle, C.; Beazley, C.; Arcelus, M.G.; Sekowska, M. et al.
Source: Self-asserted source
Barbara Stranger via Scopus - Elsevier
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