Personal information

Emails & domains

Verified email domains

Activities

Collapse all

Employment (2)

AbbVie (United States): North Chicago, US

2024-08 to present | Senior Scientist, Chemistry II (Process Chemistry)
Employment
Source: Self-asserted source
Jeremy Henle

AbbVie Inc: North Chicago, IL, US

2018-02-05 to 2024-08-01 | Senior Scientist I (Process Chemistry)
Employment
Source: Self-asserted source
Jeremy Henle

Education and qualifications (2)

University of Illinois, Urbana-Champaign: Urbana, Illinois, US

2011-08 to 2018-05 | Ph.D. (Chemistry)
Education
Source: Self-asserted source
Jeremy Henle

Illinois Wesleyan University: Bloomington, Illinois, US

2007-08 to 2011-05-02 | Bachelor of Science (Chemistry)
Education
Source: Self-asserted source
Jeremy Henle

Works (15)

Development of a Thioetherification of Heteroarene Electrophiles with Broad Scope via a Proton Transfer Dual Ionization Mechanism

Journal of the American Chemical Society
2025-02-26 | Journal article
DOI: 10.1021/jacs.4c18304
Contributors: Christian R. Zwick, III; Maike Eckhoff; Jeremy J. Henle; Anna V. Bay; Rafal Swiatowiec; Shashank Shekhar; Cassie Yang; Yong Zhou; Amanda L. Wall; Rodger F. Henry et al.
Source: check_circle
Crossref

Correction to “Application of Machine Learning and Reaction Optimization for the Iterative Improvement of Enantioselectivity of Cinchona-Derived Phase Transfer Catalysts”

Organic Process Research & Development
2024-01-19 | Journal article
DOI: 10.1021/acs.oprd.3c00475
Contributors: Katrina W. Lexa; Kevin M. Belyk; Jeremy Henle; Bangping Xiang; Robert P. Sheridan; Scott E. Denmark; Rebecca T. Ruck; Edward C. Sherer
Source: check_circle
Crossref

Continuous Process to Safely Manufacture an Aryldiazoacetate and Its Direct Use in a Dirhodium-Catalyzed Enantioselective Cyclopropanation

Organic Process Research & Development
2023-01-20 | Journal article | Author
DOI: 10.1021/acs.oprd.2c00288
Part of ISSN: 1083-6160
Part of ISSN: 1520-586X
Contributors: Stephen Lathrop; Laurie B. Mlinar; Onkar N. Manjrekar; Yong Zhou; Kaid Harper; Eric R. Sacia; Molly Higgins; Andrew Bogdan; Zhe Wang; Steven Richter et al.
Source: Self-asserted source
Jeremy Henle

Application of Machine Learning and Reaction Optimization for the Iterative Improvement of Enantioselectivity of Cinchona-Derived Phase Transfer Catalysts

Organic Process Research & Development
2022-03-18 | Journal article
DOI: 10.1021/acs.oprd.1c00155
Contributors: Katrina W. Lexa; Kevin M. Belyk; Jeremy Henle; Bangping Xiang; Robert P. Sheridan; Scott E. Denmark; Rebecca T. Ruck; Edward C. Sherer
Source: check_circle
Crossref

Mechanistic Evaluation and Solvent-Based Linear Free Energy Relationship in the Alkylation of ABT-199 Using Di-tert-butyl Chloromethyl Phosphate

Organic Process Research & Development
2022-03-18 | Journal article
DOI: 10.1021/acs.oprd.1c00363
Contributors: Kaid C. Harper; Russel Klix; Yu-Ming Pu; Jeremy Henle; Jianguo Ji; Yi-Yin Ku
Source: check_circle
Crossref

Computational methods for training set selection and error assessment applied to catalyst design: guidelines for deciding which reactions to run first and which to run next

Reaction Chemistry & Engineering
2021 | Journal article
DOI: 10.1039/D1RE00013F
Contributors: Andrew F. Zahrt; Brennan T. Rose; William T. Darrow; Jeremy J. Henle; Scott E. Denmark
Source: check_circle
Crossref

Dreams, False Starts, Dead Ends, and Redemption: A Chronicle of the Evolution of a Chemoinformatic Workflow for the Optimization of Enantioselective Catalysts.

Accounts of chemical research
2021-04-15 | Journal article
DOI: 10.1021/acs.accounts.0c00826
PMID: 33856771
Source: Self-asserted source
Jeremy Henle

Pd-Catalyzed Cross-Coupling of Hindered, Electron-Deficient Anilines with Bulky (Hetero)aryl Halides Using Biaryl Phosphorinane Ligands

ACS Catalysis
2020-12-18 | Journal article
DOI: 10.1021/acscatal.0c04280
Contributors: Alison M. Wilders; Jeremy Henle; Michael C. Haibach; Rafal Swiatowiec; Jeffrey Bien; Rodger F. Henry; Shardrack O. Asare; Amanda L. Wall; Shashank Shekhar
Source: check_circle
Crossref

Cautionary Guidelines for Machine Learning Studies with Combinatorial Datasets

ACS Combinatorial Science
2020-11-09 | Journal article
DOI: 10.1021/acscombsci.0c00118
Contributors: Andrew F. Zahrt; Jeremy J. Henle; Scott E. Denmark
Source: check_circle
Crossref

Development of a Large-Scale Route to Glecaprevir: Synthesis of the Macrocycle via Intramolecular Etherification

Organic Process Research & Development
2020-07-28 | Journal article
DOI: 10.1021/acs.oprd.0c00244
Part of ISSN: 1083-6160
Part of ISSN: 1520-586X
Source: Self-asserted source
Jeremy Henle

Development of a Computer-Guided Workflow for Catalyst Optimization. Descriptor Validation, Subset Selection, and Training Set Analysis

Journal of the American Chemical Society
2020-07-01 | Journal article
DOI: 10.1021/jacs.0c04715
Contributors: Jeremy J. Henle; Andrew F. Zahrt; Brennan T. Rose; William T. Darrow; Yang Wang; Scott E. Denmark
Source: check_circle
Crossref

Development of the Enabling Route for Glecaprevir via Ring-Closing Metathesis

Organic Process Research & Development
2020-02-21 | Journal article
DOI: 10.1021/acs.oprd.9b00469
Part of ISSN: 1083-6160
Part of ISSN: 1520-586X
Source: Self-asserted source
Jeremy Henle

Pd-Catalyzed Cross-Coupling Reactions Promoted by Biaryl Phosphorinane Ligands

ACS Catalysis
2019-12-06 | Journal article
DOI: 10.1021/acscatal.9b03012
Part of ISSN: 2155-5435
Part of ISSN: 2155-5435
Source: Self-asserted source
Jeremy Henle

Prediction of higher-selectivity catalysts by computer-driven workflow and machine learning

Science
2019-01-18 | Journal article
DOI: 10.1126/science.aau5631
Contributors: Andrew F. Zahrt; Jeremy J. Henle; Brennan T. Rose; Yang Wang; William T. Darrow; Scott E. Denmark
Source: check_circle
Crossref

Redefining q: quaternary ammonium cross sectional area (XSA) as a general descriptor for transport-limiting PTC rate approximations

Chemical Science
2015 | Journal article
DOI: 10.1039/c5sc00071h
Part of ISSN: 2041-6520
Part of ISSN: 2041-6539
Source: Self-asserted source
Jeremy Henle
How many people are using ORCID?