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neurosurgery, neurooncology
Germany

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Employment (1)

Universitätsklinikum Freiburg: Freiburg, Baden-Württemberg, DE

2021-08-01 to present | Personal Assistant to the CEO/CMO, Staff Position for Medical Strategey and Strategic Cooperations (Leitende Ärztliche Direktion)
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Astrid Weyerbrock

Works (50 of 114)

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Objective outcome measures may demonstrate continued change in functional recovery in patients with ceiling effects of subjective patient-reported outcome measures after surgery for lumbar degenerative disorders

The Spine Journal
2023-09 | Journal article
Contributors: Michal Ziga; Marketa Sosnova; Anna M. Zeitlberger; Luca Regli; Oliver Bozinov; Astrid Weyerbrock; John K. Ratliff; Martin N. Stienen; Nicolai Maldaner
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Surgery for IDH1/2 wild-type glioma invading the corpus callosum

Acta Neurochirurgica
2021 | Journal article
Contributors: Franco, Pamela; Delev, Daniel; Cipriani, Debora; Neidert, Nicolas; Kellner, Elias; Masalha, Waseem; Mercas, Bianca; Mader, Irina; Reinacher, Peter; Weyerbrock, Astrid et al.
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Patients undergoing surgery for lumbar degenerative spinal disorders favor smartphone-based objective self-assessment over paper-based patient-reported outcome measures

The Spine Journal
2021-04 | Journal article
Contributors: Marketa Sosnova; Anna Maria Zeitlberger; Michal Ziga; Oliver P. Gautschi; Luca Regli; Astrid Weyerbrock; Oliver Bozinov; Martin N. Stienen; Nicolai Maldaner
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Multifocal lumbar disc herniation at a single level: a potential pitfall for wrong side surgery

British Journal of Neurosurgery
2021-01-02 | Journal article
Contributors: Michael Fiechter; Astrid Weyerbrock; Jean-Yves Fournier
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Cooled radiofrequency for the treatment of sacroiliac joint pain - impact on pain and psychometrics: a retrospective cohort study

Scandinavian Journal of Pain
2020 | Journal article
Contributors: Kleinmann, Barbara; Wolter, Tilman; Weyerbrock, Astrid
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Digital transformation in spine research and outcome assessment

The Spine Journal
2020 | Journal article
Contributors: Maldaner, Nicolai; Tomkins-Lane, Christy; Desai, Atman; Zygourakis, Corinna C.; Weyerbrock, Astrid; Gautschi, Oliver P.; Stienen, Martin N.
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Molecular Evolution of <i>IDH</i> Wild-Type Glioblastomas Treated With Standard of Care Affects Survival and Design of Precision Medicine Trials: A Report From the EORTC 1542 Study

Journal of Clinical Oncology
2020 | Journal article
Contributors: Draaisma, Kaspar; Chatzipli, Aikaterini; Taphoorn, Martin; Kerkhof, Melissa; Weyerbrock, Astrid; Sanson, Marc; Hoeben, Ann; Lukacova, Slavka; Lombardi, Giuseppe; Leenstra, Sieger et al.
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Neurocognitive functioning and health-related quality of life in adult medulloblastoma patients: long-term outcomes of the NOA-07 study

Journal of Neuro-Oncology
2020 | Journal article
Contributors: Dirven, Linda; Luerding, Ralf; Beier, Dagmar; Bumes, Elisabeth; Reinert, Christiane; Seidel, Clemens; Bonsanto, Matteo Mario; Bremer, Michael; Rieken, Stefan; Combs, Stephanie E. et al.
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Patterns of care for ruptured aneurysms of the middle cerebral artery: analysis of a Swiss national database (Swiss SOS)

Journal of Neurosurgery
2020 | Journal article
Contributors: Maldaner, Nicolai; Steinsiepe, Valentin K.; Goldberg, Johannes; Fung, Christian; Bervini, David; May, Adrien; Bijlenga, Philippe; Schaller, Karl; Roethlisberger, Michel; Zumofen, Daniel W. et al.
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Superiority of temozolomide over radiotherapy for elderly patients with RTK II methylation class, <i>MGMT</i> promoter methylated malignant astrocytoma

Neuro-Oncology
2020 | Journal article
Contributors: Wick, Antje; Kessler, Tobias; Platten, Michael; Meisner, Christoph; Bamberg, Michael; Herrlinger, Ulrich; Felsberg, Joerg; Weyerbrock, Astrid; Papsdorf, Kirsten; Steinbach, Joachim P. et al.
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Baseline T1 hyperintense and diffusion-restricted lesions are not linked to prolonged survival in bevacizumab-treated glioblastoma patients of the GLARIUS trial

Journal of Neuro-Oncology
2019 | Journal article
EID:

2-s2.0-85069486654

Contributors: Kebir, S.; Schaub, C.; Junold, N.; Hattingen, E.; Schäfer, N.; Steinbach, J.P.; Weyerbrock, A.; Hau, P.; Goldbrunner, R.; Galldiks, N. et al.
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Astrid Weyerbrock via Scopus - Elsevier

Conscious Experience and Psychological Consequences of Awake Craniotomy

World Neurosurgery
2019 | Journal article
EID:

2-s2.0-85067474121

Contributors: Hejrati, N.; Spieler, D.; Samuel, R.; Regli, L.; Weyerbrock, A.; Surbeck, W.
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Astrid Weyerbrock via Scopus - Elsevier

Correction to: Ruptured PICA aneurysms: presentation and treatment outcomes compared to other posterior circulation aneurysms. A Swiss SOS study (Acta Neurochirurgica, (2019), 161, 7, (1325-1334), 10.1007/s00701-019-03894-5)

Acta Neurochirurgica
2019 | Journal article
EID:

2-s2.0-85066025065

Contributors: Starnoni, D.; Maduri, R.; Al Taha, K.; Bervini, D.; Zumofen, D.W.; Stienen, M.N.; Schatlo, B.; Fung, C.; Robert, T.; Seule, M.A. et al.
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Astrid Weyerbrock via Scopus - Elsevier

Cyclooxygenase (COX) Inhibition by Acetyl Salicylic Acid (ASA) Enhances Antitumor Effects of Nitric Oxide in Glioblastoma In Vitro

Molecular Neurobiology
2019 | Journal article
EID:

2-s2.0-85061193502

Contributors: Guenzle, J.; Garrelfs, N.W.C.; Goeldner, J.M.; Weyerbrock, A.
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Astrid Weyerbrock via Scopus - Elsevier

Intracranial meningiomas: A neurosurgical disease? Possibilities and limitations of surgery,Intrakranielle Meningeome: Ein neurochirurgisches Krankheitsbild?: Möglichkeiten und Grenzen der Operation

Praxis
2019 | Journal article
EID:

2-s2.0-85072288288

Contributors: Kogias, E.; Weyerbrock, A.
Source: Self-asserted source
Astrid Weyerbrock via Scopus - Elsevier

Intradural non-calcified thoracic disc herniation causing spontaneous intracranial hypotension: a case report

BMC Surgery
2019 | Journal article
Contributors: Fiechter, Michael; Ott, Alexander; Beck, Juergen; Weyerbrock, Astrid; Fournier, Jean-Yves
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Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA–09): a randomised, open-label, phase 3 trial

The Lancet
2019 | Journal article
EID:

2-s2.0-85061381459

Contributors: Herrlinger, U.; Tzaridis, T.; Mack, F.; Steinbach, J.P.; Schlegel, U.; Sabel, M.; Hau, P.; Kortmann, R.-D.; Krex, D.; Grauer, O. et al.
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Astrid Weyerbrock via Scopus - Elsevier

Objective functional assessment using the "Timed Up and Go" test in patients with lumbar spinal stenosis

Neurosurgical Focus
2019 | Journal article
Contributors: Stienen, Martin N.; Maldaner, Nicolai; Joswig, Holger; Corniola, Marco, V; Bellut, David; Proemmel, Peter; Regli, Luca; Weyerbrock, Astrid; Schaller, Karl; Gautschi, Oliver P.
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Ruptured PICA aneurysms: presentation and treatment outcomes compared to other posterior circulation aneurysms. A Swiss SOS study

Acta Neurochirurgica
2019 | Journal article
EID:

2-s2.0-85065194723

Contributors: Starnoni, D.; Maduri, R.; Al Taha, K.; Bervini, D.; Zumofen, D.W.; Stienen, M.N.; Schatlo, B.; Fung, C.; Robert, T.; Seule, M.A. et al.
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Astrid Weyerbrock via Scopus - Elsevier

Ruptured posterior circulation aneurysms: epidemiology, patterns of care, and outcomes from the Swiss SOS national registry

Acta Neurochirurgica
2019 | Journal article
EID:

2-s2.0-85060738403

Contributors: Maduri, R.; Starnoni, D.; Rocca, A.; Bervini, D.; Zumofen, D.W.; Stienen, M.N.; Schatlo, B.; Fung, C.; Robert, T.; Seule, M.A. et al.
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Astrid Weyerbrock via Scopus - Elsevier

Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF

Cancer Immunology Research
2019 | Journal article
Contributors: Di Tacchio, Mariangela; Macas, Jadranka; Weissenberger, Jakob; Sommer, Kathleen; Baehr, Oliver; Steinbach, Joachim P.; Senft, Christian; Seifert, Volker; Glas, Martin; Herrlinger, Ulrich et al.
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Different but similar: Personality traits of surgeons and internists - Results of a cross-sectional observational study

BMJ Open
2018 | Journal article
EID:

2-s2.0-85049968415

Contributors: Stienen, M.N.; Scholtes, F.; Samuel, R.; Weil, A.; Weyerbrock, A.; Surbeck, W.
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Astrid Weyerbrock via Scopus - Elsevier

Home-Time as a Surrogate Marker for Functional Outcome After Aneurysmal Subarachnoid Hemorrhage

Stroke
2018 | Journal article
Contributors: Stienen, Martin Nikolaus; Smoll, Nicolas Roydon; Fung, Christian; Goldberg, Johannes; Bervini, David; Chiappini, Alessio; Robert, Thomas; May, Adrien; Bijlenga, Philippe; Zumofen, Daniel et al.
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LONG-TERM ANALYSES OF THE NOA-08 RANDOMIZED PHASE III TRIAL

Neuro-Oncology
2018 | Journal article
Contributors: Kessler, Tobias; Wick, Antje; Platten, Michael; Meisner, Christoph; Bamberg, Michael; Herrlinger, Ulrich; Felsberg, Joerg; Weyerbrock, Astrid; Seidel, Clemens; Steinbach, Joachim et al.
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Multicenter pilot study of radiochemotherapy as first-line treatment for adults with medulloblastoma (NOA-07)

Neuro-Oncology
2018 | Journal article
EID:

2-s2.0-85042271382

Contributors: Beier, D.; Proescholdt, M.; Reinert, C.; Pietsch, T.; Jones, D.T.W.; Pfister, S.M.; Hattingen, E.; Seidel, C.; Dirven, L.; Luerding, R. et al.
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Astrid Weyerbrock via Scopus - Elsevier

Predictors of In-Hospital Death After Aneurysmal Subarachnoid Hemorrhage: Analysis of a Nationwide Database (Swiss SOS [Swiss Study on Aneurysmal Subarachnoid Hemorrhage])

Stroke
2018 | Journal article
Contributors: Stienen, Martin Nikolaus; Germans, Menno; Burkhardt, Jan-Karl; Neidert, Marian C.; Fung, Christian; Bervini, David; Zumofen, Daniel; Rothlisberger, Michel; Marbacher, Serge; Maduri, Rodolfo et al.
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Predictors of Occurrence and Anatomic Distribution of Multiple Aneurysms in Patients with Aneurysmal Subarachnoid Hemorrhage

World Neurosurgery
2018 | Journal article
EID:

2-s2.0-85040516556

Contributors: Roethlisberger, M.; Achermann, R.; Bawarjan, S.; Stienen, M.N.; Fung, C.; D'Alonzo, D.; Maldaner, N.; Ferrari, A.; Corniola, M.V.; Schöni, D. et al.
Source: Self-asserted source
Astrid Weyerbrock via Scopus - Elsevier

Quality of life in the GLARIUS trial randomizing bevacizumab/irinotecan versus temozolomide in newly diagnosed, MGMT-nonmethylated glioblastoma

Neuro-Oncology
2018 | Journal article
EID:

2-s2.0-85045535791

Contributors: Schäfer, N.; Proescholdt, M.; Steinbach, J.P.; Weyerbrock, A.; Hau, P.; Grauer, O.; Goldbrunner, R.; Friedrich, F.; Rohde, V.; Ringel, F. et al.
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Astrid Weyerbrock via Scopus - Elsevier

The barrow neurological institute grading scale as a predictor for delayed cerebral ischemia and outcome after aneurysmal subarachnoid hemorrhage: Data from a nationwide patient registry (Swiss SOS)

Clinical Neurosurgery
2018 | Journal article
EID:

2-s2.0-85056609289

Contributors: Neidert, M.C.; Maldaner, N.; Stienen, M.N.; Roethlisberger, M.; Zumofen, D.W.; D'Alonzo, D.; Marbacher, S.; Maduri, R.; Hostettler, I.C.; Schatlo, B. et al.
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Astrid Weyerbrock via Scopus - Elsevier

Tumor growth patterns of MGMT-non-methylated glioblastoma in the randomized GLARIUS trial

Journal of Cancer Research and Clinical Oncology
2018 | Journal article
EID:

2-s2.0-85047661416

Contributors: Schaub, C.; Kebir, S.; Junold, N.; Hattingen, E.; Schäfer, N.; Steinbach, J.P.; Weyerbrock, A.; Hau, P.; Goldbrunner, R.; Niessen, M. et al.
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Astrid Weyerbrock via Scopus - Elsevier

<i>KLF</i>6 depletion promotes NF-κB signaling in glioblastoma

Oncogene
2017 | Journal article
Contributors: Masilamani, A. P.; Ferrarese, R.; Kling, E.; Thudi, N. K.; Kim, H.; Scholtens, D. M.; Dai, F.; Hadler, M.; Unterkircher, T.; Platania, L. et al.
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C-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas

Oncotarget
2017 | Journal article
EID:

2-s2.0-85010790066

Contributors: Heiland, D.H.; Ferrarese, R.; Claus, R.; Dai, F.; Masilamani, A.P.; Kling, E.; Weyerbrock, A.; Kling, T.; Nelander, S.; Carro, M.S.
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Astrid Weyerbrock via Scopus - Elsevier

Clinical relevance of anterior cerebral artery asymmetry in aneurysmal subarachnoid hemorrhage

Journal of Neurosurgery
2017 | Journal article
EID:

2-s2.0-85029308946

Contributors: Jabbarli, R.; Reinhard, M.; Roelz, R.; Kaier, K.; Weyerbrock, A.; Taschner, C.; Scheiwe, C.; Shah, M.
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Astrid Weyerbrock via Scopus - Elsevier

Comprehensive analysis of PD-L1 expression in glioblastoma multiforme

Oncotarget
2017 | Journal article
EID:

2-s2.0-85021266905

Contributors: Heiland, D.H.; Haaker, G.; Delev, D.; Mercas, B.; Masalha, W.; Heynckes, S.; Gäbelein, A.; Pfeifer, D.; Carro, M.S.; Weyerbrock, A. et al.
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Astrid Weyerbrock via Scopus - Elsevier

Computed tomography angiography spot sign predicts intraprocedural aneurysm rupture in subarachnoid hemorrhage

Acta Neurochirurgica
2017 | Journal article
EID:

2-s2.0-85010735670

Contributors: Burkhardt, J.-K.; Neidert, M.C.; Stienen, M.N.; Schöni, D.; Fung, C.; Roethlisberger, M.; Corniola, M.V.; Bervini, D.; Maduri, R.; Valsecchi, D. et al.
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Astrid Weyerbrock via Scopus - Elsevier

Epigenetic regulation of ZBTB18 promotes glioblastoma progression

Molecular Cancer Research
2017 | Journal article
EID:

2-s2.0-85026667027

Contributors: Fedele, V.; Dai, F.; Masilamani, A.P.; Heiland, D.H.; Kling, E.; Gätjens-Sanchez, A.M.; Ferrarese, R.; Platania, L.; Soroush, D.; Kim, H. et al.
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Astrid Weyerbrock via Scopus - Elsevier

Integrative diffusion-weighted imaging and radiogenomic network analysis of glioblastoma multiforme

Scientific Reports
2017 | Journal article
EID:

2-s2.0-85014947663

Contributors: Heiland, D.H.; Simon-Gabriel, C.P.; Demerath, T.; Haaker, G.; Pfeifer, D.; Kellner, E.; Kiselev, V.G.; Staszewski, O.; Urbach, H.; Weyerbrock, A. et al.
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Astrid Weyerbrock via Scopus - Elsevier

Mesoscopic imaging of glioblastomas: Are diffusion, perfusion and spectroscopic measures influenced by the radiogenetic phenotype?

Neuroradiology Journal
2017 | Journal article
EID:

2-s2.0-85011587031

Contributors: Demerath, T.; Simon-Gabriel, C.P.; Kellner, E.; Schwarzwald, R.; Lange, T.; Heiland, D.H.; Reinacher, P.; Staszewski, O.; Mast, H.; Kiselev, V.G. et al.
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Astrid Weyerbrock via Scopus - Elsevier

Molecular differences between cerebral blood volume and vessel size in glioblastoma multiforme

Oncotarget
2017 | Journal article
EID:

2-s2.0-85012929403

Contributors: Heiland, D.H.; Demerath, T.; Kellner, E.; Kiselev, V.G.; Pfeifer, D.; Schnell, O.; Staszewski, O.; Urbach, H.; Weyerbrock, A.; Mader, I.
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Astrid Weyerbrock via Scopus - Elsevier

MOLECULAR GENETIC, HOST-DERIVED AND CLINICAL DETERMINANTS OF LONG-TERM SURVIVAL IN GLIOBLASTOMA: FIRST RESULTS FROM THE BRAIN TUMOR FUNDERS' COLLABORATIVE CONSORTIUM

Neuro-Oncology
2017 | Journal article
Contributors: Happold, Caroline; Felsberg, Joerg; Clarke, Jennifer; Soffietti, Riccardo; Marosi, Christine; Krex, Dietmar; Ducray, Francois; Hau, Peter; Reijneveld, Jaap; Weyerbrock, Astrid et al.
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PHASE III TRIAL OF CCNU/TEMOZOLOMIDE (TMZ) COMBINATION THERAPY VS. STANDARD TMZ THERAPY FOR NEWLY DIAGNOSED MGMT-METHYLATED GLIOBLASTOMA PATIENTS: THE CeTeg/NOA-09 trial

Neuro-Oncology
2017 | Journal article
Contributors: Herrlinger, Ulrich; Tzaridis, Theophilos; Mack, Frederic; Steinbach, Joachim; Schlegel, Uwe; Sabel, Michael; Hau, Peter; Kortman, Rolf-Dieter; Krex, Dietmar; Grauer, Oliver et al.
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Surgical Treatment of Mesiotemporal Lobe Epilepsy: Which Approach is Favorable?

Neurosurgery
2017 | Journal article
Contributors: Schmeiser, Barbara; Wagner, Kathrin; Schulze-Bonhage, Andreas; Mader, Irina; Wendling, Anne-Sophie; Steinhoff, Bernhard Jochen; Prinz, Marco; Scheiwe, Christian; Weyerbrock, Astrid; Zentner, Josef
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The nitric oxide donor JS-K sensitizes U87 glioma cells to repetitive irradiation

Tumor Biology
2017 | Journal article
Contributors: Heckler, Max; Osterberg, Nadja; Guenzle, Jessica; Thiede-Stan, Nina Kristin; Reichardt, Wilfried; Weidensteiner, Claudia; Saavedra, Joseph E.; Weyerbrock, Astrid
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Whole Transcriptome Screening Reveals Myelination Deficits in Dysplastic Human Temporal Neocortex

Cerebral Cortex
2017 | Journal article
Contributors: Donkels, Catharina; Pfeifer, Dietmar; Janz, Philipp; Huber, Susanne; Nakagawa, Julia; Prinz, Marco; Schulze-Bonhage, Andreas; Weyerbrock, Astrid; Zentner, Josef; Haas, Carola A.
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ATF3 reduces migration capacity by regulation of matrix metalloproteinases via NFκB and STAT3 inhibition in glioblastoma

Cell Death Discovery
2017-02-27 | Journal article
Contributors: Jessica Guenzle; Louisa J Wolf; Nicklas W C Garrelfs; Jonathan M Goeldner; Nadja Osterberg; Cora R Schindler; Joseph E Saavedra; Astrid Weyerbrock
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Amino-acid PET versus MRI guided re-irradiation in patients with recurrent glioblastoma multiforme (GLIAA) - Protocol of a randomized phase II trial (NOA 10/ARO 2013-1)

BMC Cancer
2016 | Journal article
EID:

2-s2.0-84991624743

Contributors: Oehlke, O.; Mix, M.; Graf, E.; Schimek-Jasch, T.; Nestle, U.; Götz, I.; Schneider-Fuchs, S.; Weyerbrock, A.; Mader, I.; Baumert, B.G. et al.
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Astrid Weyerbrock via Scopus - Elsevier

Bevacizumab Plus irinotecan versus temozolomide in newly diagnosed O<sup>6</sup>-methylguanine-DNA methyltransferase nonmethylated glioblastoma: The randomized GLARIUS trial

Journal of Clinical Oncology
2016 | Journal article
EID:

2-s2.0-84969921399

Contributors: Herrlinger, U.; Schäfer, N.; Steinbach, J.P.; Weyerbrock, A.; Hau, P.; Goldbrunner, R.; Friedrich, F.; Rohde, V.; Ringel, F.; Schlegel, U. et al.
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Astrid Weyerbrock via Scopus - Elsevier

CHARACTERIZATION OF GLIOBLASTOMA SUBTYPES BY INTEGRATIVE ANALYSIS OF MATCHED GENE EXPRESSION AND ADVANCED MAGNETIC RESONANCE IMAGING DATA

Neuro-Oncology
2016 | Journal article
Contributors: Simon-Gabriel, Carl Philipp; Weyerbrock, Astrid; Guggenberger, Konstanze; Pfeifer, Dietmar; Kellner, Elias; Schnell, Oliver; Urbach, Horst; Mader, Irina; Heiland, Dieter Henrik
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Clinical benefit from resection of recurrent glioblastomas: Results of a multicenter study including 503 patients with recurrent glioblastomas undergoing surgical resection

Neuro-Oncology
2016 | Journal article
EID:

2-s2.0-84960426654

Contributors: Ringel, F.; Pape, H.; Sabel, M.; Krex, D.; Bock, H.C.; Misch, M.; Weyerbrock, A.; Westermaier, T.; Senft, C.; Schucht, P. et al.
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Astrid Weyerbrock via Scopus - Elsevier

Decrease of VEGF-A in myeloid cells attenuates glioma progression and prolongs survival in an experimental glioma model

Neuro-Oncology
2016 | Journal article
Contributors: Osterberg, Nadja; Ferrara, Napoleone; Vacher, Jean; Gaedicke, Simone; Niedermann, Gabriele; Weyerbrock, Astrid; Doostkam, Soroush; Schaefer, Hans-Eckart; Plate, Karl H.; Machein, Marcia Regina
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