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Human induced pluripotent stem cells, Proteomics, Bioinformatics
United States

Biography

I am an Assistant Professor at the University of Colorado School of Medicine. We have a wide range of research interests that encompass several areas of biochemistry and cell biology, including:

Protein turnover: development and application of stable isotope labeling mass spectrometry methods to measure protein half-life

Spatial proteomics: subcellular distributions of proteins, interaction between spatial and temporal protein dynamics

Cellular physiology: cellular crosstalk by secretome proteins, signatures of cellular senescence, cardiotoxicity and proteostatic disruptions in induced pluripotent stem cell models

Bioinformatics: correlation and discrepancies of transcript and protein levels, protein prediction with machine learning

Our work is supported by various funding sources, including an NHLBI K99/R00 award, an NHLBI R01 grant, an NIGMS R35 MIRA award, and the University of Colorado Translational Research Scholars Program. Please inquire if you are interested in working with us to examine how proteins orchestrate biological processes in development and disease.

Activities

Employment (5)

University of Colorado School of Medicine: Aurora, CO, US

2020-02-01 to present | Assistant Professor (Medicine)
Employment
Source: Self-asserted source
Edward Lau

Stanford University: Stanford, CA, US

2019-07-01 to 2020-01-31 | Instructor (Stanford Cardiovascular Institute)
Employment
Source: Self-asserted source
Edward Lau

Stanford University: Palo Alto, CA, US

2017-09-01 to 2019-06-30 | Postdoctoral Fellow (Medicine)
Employment
Source: Self-asserted source
Edward Lau

University of California Los Angeles: Los Angeles, CA, US

2016-01-01 to 2017-09-31 | Assistant Project Scientist (Physiology)
Employment
Source: Self-asserted source
Edward Lau

Scripps Research Institute: La Jolla, CA, US

2006-06-01 to 2007-03-01 | Lab Assistant (Chemical Physiology)
Employment
Source: Self-asserted source
Edward Lau

Education and qualifications (2)

University of California at Los Angeles: Los Angeles, CA, US

2010-09-26 to 2015-06-12 | PhD (Proteomics)
Education
Source: Self-asserted source
Edward Lau

University of California at Berkeley: Berkeley, CA, US

2002-09-20 to 2006-05-22 | BA (Molecular and Cell Biology)
Education
Source: Self-asserted source
Edward Lau

Funding (2)

Investigations of proteome turnover kinetics under cellular differentiation

2022-09-17 to 2027-07-31 | Grant
National Institute of General Medical Sciences (Bethesda, US)
GRANT_NUMBER: R35GM146815
Source: Self-asserted source
Edward Lau via DimensionsWizard

Investigating systems physiology with multi-omics data

2021-09-22 to 2023-09-21 | Grant
Office of the Director (Bethesda, US)
GRANT_NUMBER: R03OD032666
Source: Self-asserted source
Edward Lau via DimensionsWizard

Peer review (9 reviews for 7 publications/grants)

Review activity for Cell genomics. (1)
Review activity for Cell reports. (2)
Review activity for Communications chemistry. (2)
Review activity for Journal of proteome research. (1)
Review activity for Nature communications (1)
Review activity for Nature metabolism. (1)
Review activity for Nature structural & molecular biology. (1)