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Microbiome-based biomarkers to guide personalized microbiome-based therapies for Parkinson’s disease

2024-04-04 | Preprint
Contributors: Haydeh Payami; Timothy R Sampson; Charles F Murchison; Zachary D Wallen
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Crossref

Alpha-synuclein overexpression can drive microbiome dysbiosis in mice

2024-02-01 | Preprint
Contributors: Timothy R. Sampson; Zachary D Wallen; Woong-Jai Won; David G. Standaert; Haydeh Payami; Ashley S. Harms
Source: check_circle
Crossref

Population fraction of Parkinson’s disease attributable to preventable risk factors

npj Parkinson's Disease
2023-12-05 | Journal article
Contributors: Haydeh Payami; Gwendolyn Cohen; Charles F. Murchison; Timothy R. Sampson; David G. Standaert; Zachary D. Wallen
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Crossref

Population fraction of Parkinson’s disease attributable to preventable risk factors

2023-05-19 | Preprint
Contributors: Haydeh Payami; Gwendolyn Cohen; Charles F Murchison; Timothy R Sampson; David G Standaert; Zachary D Wallen
Source: check_circle
Crossref

Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms

Nature Communications
2022-11-15 | Journal article
Contributors: Zachary D. Wallen; Ayse Demirkan; Guy Twa; Gwendolyn Cohen; Marissa N. Dean; David G. Standaert; Timothy R. Sampson; Haydeh Payami
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Crossref

Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms

2022-06-12 | Preprint
Contributors: Zachary D Wallen; Ayse Demirkan; Guy Twa; Gwendolyn Cohen; Marissa N Dean; David G Standaert; Timothy Sampson; Haydeh Payami
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Crossref

Exploring human-genome gut-microbiome interaction in Parkinson’s disease

npj Parkinson's Disease
2021-08-18 | Journal article
Contributors: Zachary D. Wallen; William J. Stone; Stewart A. Factor; Eric Molho; Cyrus P. Zabetian; David G. Standaert; Haydeh Payami
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Crossref

Genetics of human gut microbiome composition

2020-06 | Other
OTHER-ID:

PPR181241

Contributors: Kurilshikov A; Medina-Gomez C; Bacigalupe R; Radjabzadeh D; Wang J; Demirkan A; Le Roy CI; Raygoza Garay JA; Finnicum CT; Liu X et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Characterizing dysbiosis of gut microbiome in PD: evidence for overabundance of opportunistic pathogens

npj Parkinson's Disease
2020-06-12 | Journal article
Contributors: Zachary D. Wallen; Mary Appah; Marissa N. Dean; Cheryl L. Sesler; Stewart A. Factor; Eric Molho; Cyrus P. Zabetian; David G. Standaert; Haydeh Payami
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Crossref

Characterizing dysbiosis of gut microbiome in PD: Evidence for overabundance of opportunistic pathogens

2020-01 | Other
OTHER-ID:

PPR108727

Contributors: Wallen ZD; Appah M; Dean MN; Sesler CL; Factor SA; Molho E; Zabetian CP; Standaert DG; Payami H
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Using global team science to identify genetic parkinson's disease worldwide.

Annals of neurology
2019-06 | Journal article
Contributors: Vollstedt EJ; Kasten M; Klein C; MJFF Global Genetic Parkinson's Disease Study Group
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Plasticity-related gene 3 (LPPR1) and age at diagnosis of Parkinson disease.

Neurology. Genetics
2018-10 | Journal article
Contributors: Wallen ZD; Chen H; Hill-Burns EM; Factor SA; Zabetian CP; Payami H
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative.

Microbiome
2018-06 | Journal article
Contributors: Wang J; Kurilshikov A; Radjabzadeh D; Turpin W; Croitoru K; Bonder MJ; Jackson MA; Medina-Gomez C; Frost F; Homuth G et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Stool Immune Profiles Evince Gastrointestinal Inflammation in Parkinson's Disease.

Movement disorders : official journal of the Movement Disorder Society
2018-03 | Journal article
Contributors: Houser MC; Chang J; Factor SA; Molho ES; Zabetian CP; Hill-Burns EM; Payami H; Hertzberg VS; Tansey MG
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease.

Science translational medicine
2018-01 | Journal article
Contributors: Hui KY; Fernandez-Hernandez H; Hu J; Schaffner A; Pankratz N; Hsu NY; Chuang LS; Carmi S; Villaverde N; Li X et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

The emerging science of precision medicine and pharmacogenomics for Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society
2017-07 | Journal article
Contributors: Payami H
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Caffeine, creatine, GRIN2A and Parkinson's disease progression.

Journal of the neurological sciences
2017-02 | Journal article
Contributors: Simon DK; Wu C; Tilley BC; Lohmann K; Klein C; Payami H; Wills AM; Aminoff MJ; Bainbridge J; Dewey R et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome.

Movement disorders : official journal of the Movement Disorder Society
2017-02 | Journal article
Contributors: Hill-Burns EM; Debelius JW; Morton JT; Wissemann WT; Lewis MR; Wallen ZD; Peddada SD; Factor SA; Molho E; Zabetian CP et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Identification of genetic modifiers of age-at-onset for familial Parkinson's disease.

Human molecular genetics
2016-07 | Journal article
Contributors: Hill-Burns EM; Ross OA; Wissemann WT; Soto-Ortolaza AI; Zareparsi S; Siuda J; Lynch T; Wszolek ZK; Silburn PA; Mellick GD et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

DNA variants in CACNA1C modify Parkinson disease risk only when vitamin D level is deficient.

Neurology. Genetics
2016-04 | Journal article
Contributors: Wang L; Maldonado L; Beecham GW; Martin ER; Evatt ML; Ritchie JC; Haines JL; Zabetian CP; Payami H; Pericak-Vance MA et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Glutamate receptor gene GRIN2A, coffee, and Parkinson disease.

PLoS genetics
2014-11 | Journal article
Contributors: Hamza TH; Hill-Burns EM; Scott WK; Vance JM; Factor SA; Zabetian CP; Payami H
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

The relationship between obsessive-compulsive symptoms and PARKIN genotype: The CORE-PD study.

Movement disorders : official journal of the Movement Disorder Society
2014-11 | Journal article
Contributors: Sharp ME; Caccappolo E; Mejia-Santana H; Tang MX; Rosado L; Orbe Reilly M; Ruiz D; Louis ED; Comella C; Nance M et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Global investigation and meta-analysis of the C9orf72 (G4C2)n repeat in Parkinson disease.

Neurology
2014-10 | Journal article
Contributors: Theuns J; Verstraeten A; Sleegers K; Wauters E; Gijselinck I; Smolders S; Crosiers D; Corsmit E; Elinck E; Sharma M et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.

Nature genetics
2014-07 | Journal article
Contributors: Nalls MA; Pankratz N; Lill CM; Do CB; Hernandez DG; Saad M; DeStefano AL; Kara E; Bras J; Sharma M et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Identification of a novel Parkinson's disease locus via stratified genome-wide association study.

BMC genomics
2014-02 | Journal article
Contributors: Hill-Burns EM; Wissemann WT; Hamza TH; Factor SA; Zabetian CP; Payami H
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Cognitive and motor function in long-duration PARKIN-associated Parkinson disease.

JAMA neurology
2014-01 | Journal article
Contributors: Alcalay RN; Caccappolo E; Mejia-Santana H; Tang MX; Rosado L; Orbe Reilly M; Ruiz D; Louis ED; Comella CL; Nance MA et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Promise of pharmacogenomics for drug discovery, treatment and prevention of Parkinson's disease. A perspective.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
2014-01 | Journal article
Contributors: Payami H; Factor SA
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Association of Parkinson disease with structural and regulatory variants in the HLA region.

American journal of human genetics
2013-10 | Journal article
Contributors: Wissemann WT; Hill-Burns EM; Zabetian CP; Factor SA; Patsopoulos N; Hoglund B; Holcomb C; Donahue RJ; Thomson G; Erlich H et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Protective effect of LRRK2 p.R1398H on risk of Parkinson's disease is independent of MAPT and SNCA variants.

Neurobiology of aging
2013-08 | Journal article
Contributors: Heckman MG; Elbaz A; Soto-Ortolaza AI; Serie DJ; Aasly JO; Annesi G; Auburger G; Bacon JA; Boczarska-Jedynak M; Bozi M et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

A genetic basis for the variable effect of smoking/nicotine on Parkinson's disease.

The pharmacogenomics journal
2012-10 | Journal article
Contributors: Hill-Burns EM; Singh N; Ganguly P; Hamza TH; Montimurro J; Kay DM; Yearout D; Sheehan P; Frodey K; McLear JA et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Exploratory analysis of seven Alzheimer's disease genes: disease progression.

Neurobiology of aging
2012-10 | Journal article
Contributors: Ruiz A; Hernández I; Ronsende-Roca M; González-Pérez A; Rodriguez-Noriega E; Ramírez-Lorca R; Mauleón A; Moreno-Rey C; Boswell L; Tune L et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Cognitive performance of GBA mutation carriers with early-onset PD: the CORE-PD study.

Neurology
2012-03 | Journal article
Contributors: Alcalay RN; Caccappolo E; Mejia-Santana H; Tang M-; Rosado L; Orbe Reilly M; Ruiz D; Ross B; Verbitsky M; Kisselev S et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

PLoS genetics
2012-03 | Journal article
Contributors: Lill CM; Roehr JT; McQueen MB; Kavvoura FK; Bagade S; Schjeide BM; Schjeide LM; Meissner E; Zauft U; Allen NC et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.

Annals of neurology
2012-03 | Journal article
Contributors: Pankratz N; Beecham GW; DeStefano AL; Dawson TM; Doheny KF; Factor SA; Hamza TH; Hung AY; Hyman BT; Ivinson AJ et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Evidence for more than one Parkinson's disease-associated variant within the HLA region.

PloS one
2011-11 | Journal article
Contributors: Hill-Burns EM; Factor SA; Zabetian CP; Thomson G; Payami H
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

An attempt to replicate interaction between coffee and CYP1A2 gene in connection to Parkinson's disease.

European journal of neurology
2011-09 | Journal article
Contributors: Hill-Burns EM; Hamza TH; Zabetian CP; Factor SA; Payami H
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Genome-wide gene-environment study identifies glutamate receptor gene GRIN2A as a Parkinson's disease modifier gene via interaction with coffee.

PLoS genetics
2011-08 | Journal article
Contributors: Hamza TH; Chen H; Hill-Burns EM; Rhodes SL; Montimurro J; Kay DM; Tenesa A; Kusel VI; Sheehan P; Eaaswarkhanth M et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Disease-related and genetic correlates of psychotic symptoms in Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society
2011-06 | Journal article
Contributors: Factor SA; Steenland NK; Higgins DS; Molho ES; Kay DM; Montimurro J; Rosen AR; Zabetian CP; Payami H
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

SNCA variant associated with Parkinson disease and plasma alpha-synuclein level.

Archives of neurology
2010-11 | Journal article
Contributors: Mata IF; Shi M; Agarwal P; Chung KA; Edwards KL; Factor SA; Galasko DR; Ginghina C; Griffith A; Higgins DS et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Novel pathogenic LRRK2 p.Asn1437His substitution in familial Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society
2010-10 | Journal article
Contributors: Aasly JO; Vilariño-Güell C; Dachsel JC; Webber PJ; West AB; Haugarvoll K; Johansen KK; Toft M; Nutt JG; Payami H et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

A comprehensive analysis of deletions, multiplications, and copy number variations in PARK2.

Neurology
2010-09 | Journal article
Contributors: Kay DM; Stevens CF; Hamza TH; Montimurro JS; Zabetian CP; Factor SA; Samii A; Griffith A; Roberts JW; Molho ES et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Postural instability/gait disturbance in Parkinson's disease has distinct subtypes: an exploratory analysis.

Journal of neurology, neurosurgery, and psychiatry
2010-09 | Journal article
Contributors: Factor SA; Steenland NK; Higgins DS; Molho ES; Kay DM; Montimurro J; Rosen AR; Zabetian CP; Payami H
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease.

Nature genetics
2010-08 | Journal article
Contributors: Hamza TH; Zabetian CP; Tenesa A; Laederach A; Montimurro J; Yearout D; Kay DM; Doheny KF; Paschall J; Pugh E et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

The heritability of risk and age at onset of Parkinson's disease after accounting for known genetic risk factors.

Journal of human genetics
2010-03 | Journal article
Contributors: Hamza TH; Payami H
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Visualizing disease associations: graphic analysis of frequency distributions as a function of age using moving average plots (MAP) with application to Alzheimer's and Parkinson's disease.

Genetic epidemiology
2010-01 | Journal article
Contributors: Payami H; Kay DM; Zabetian CP; Schellenberg GD; Factor SA; McCulloch CC
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Genetic association between alpha-synuclein and idiopathic Parkinson's disease.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
2008-10 | Journal article
Contributors: Kay DM; Factor SA; Samii A; Higgins DS; Griffith A; Roberts JW; Leis BC; Nutt JG; Montimurro JS; Keefe RG et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study.

The Lancet. Neurology
2008-06 | Journal article
Contributors: Healy DG; Falchi M; O'Sullivan SS; Bonifati V; Durr A; Bressman S; Brice A; Aasly J; Zabetian CP; Goldwurm S et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Combined effects of smoking, coffee, and NSAIDs on Parkinson's disease risk.

Movement disorders : official journal of the Movement Disorder Society
2008-01 | Journal article
Contributors: Powers KM; Kay DM; Factor SA; Zabetian CP; Higgins DS; Samii A; Nutt JG; Griffith A; Leis B; Roberts JW et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Exploring gene-environment interactions in Parkinson's disease.

Human genetics
2008-01 | Journal article
Contributors: McCulloch CC; Kay DM; Factor SA; Samii A; Nutt JG; Higgins DS; Griffith A; Roberts JW; Leis BC; Montimurro JS et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central

Lack of evidence for an association between UCHL1 S18Y and Parkinson's disease.

European journal of neurology
2007-12 | Journal article
Contributors: Hutter CM; Samii A; Factor SA; Nutt JG; Higgins DS; Bird TD; Griffith A; Roberts JW; Leis BC; Montimurro JS et al.
Source: Self-asserted source
Haydeh Payami via Europe PubMed Central
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Peer review (15 reviews for 4 publications/grants)

Review activity for Communications medicine. (1)
Review activity for Nature communications (3)
Review activity for Nature medicine. (1)
Review activity for NPJ Parkinson's disease. (10)