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ResearcherID: Y-5513-2018
Ciência ID: 9C12-DCFB-519B
Loop profile: 2192021

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Employment (3)

Leiden University Medical Center: Leiden, NL

2017-07-16 to present | Assistant Professor - Head, Leiden Genome Technology Center (Human Genetics)
Employment
Source: Self-asserted source
Susan Kloet

Radboud University Nijmegen: Nijmegen, Gelderland, NL

2014-02-01 to 2017-05-31 | Postdoctoral Fellow (Molecular Biology)
Employment
Source: Self-asserted source
Susan Kloet

Universitair Medisch Centrum Utrecht: Utrecht, Utrecht, NL

2013-01-16 to 2014-01-31 | Postdoctoral Fellow (Molecular Cancer Research)
Employment
Source: Self-asserted source
Susan Kloet

Education and qualifications (2)

University of Washington: Seattle, WA, US

2006-09-01 to 2012-06-30 | PhD (Molecular and Cellular Biology)
Education
Source: Self-asserted source
Susan Kloet

Cornell University: Ithaca, NY, US

2002-08-26 to 2006-05-28 | BA (Biology)
Education
Source: Self-asserted source
Susan Kloet

Works (24)

Genome-wide Cas9-mediated screening of essential non-coding regulatory elements via libraries of paired single-guide RNAs

Nature Biomedical Engineering
2024-05-22 | Journal article
DOI: 10.1038/s41551-024-01204-8
Contributors: Yufeng Li; Minkang Tan; Almira Akkari-Henić; Limin Zhang; Maarten Kip; Shengnan Sun; Jorian J. Sepers; Ningning Xu; Yavuz Ariyurek; Susan L. Kloet et al.
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Acquisition of a glycosylated B-cell receptor drives follicular lymphoma toward a dark zone phenotype

Blood Advances
2023-10-10 | Journal article
DOI: 10.1182/bloodadvances.2023010725
Contributors: Cornelis A. M. van Bergen; Susan L. Kloet; Edwin Quinten; Julieta H. Sepúlveda Yáñez; Roberta Menafra; Marieke Griffioen; Patty M. Jansen; Marvyn T. Koning; Jeroen Knijnenburg; Marcelo A. Navarrete et al.
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Crossref

Detailed molecular and epigenetic characterization of the pig IPEC-J2 and chicken SL-29 cell lines

iScience
2023-03 | Journal article
DOI: 10.1016/j.isci.2023.106252
Part of ISSN: 2589-0042
Contributors: Jani de Vos; Richard P.M.A. Crooijmans; Martijn F.L. Derks; Susan L. Kloet; Bert Dibbits; Martien A.M. Groenen; Ole Madsen
Source: Self-asserted source
Susan Kloet

From gene to dose: Long-read sequencing and *-allele tools to refine phenotype predictions of CYP2C19

Frontiers in Pharmacology
2023-03-01 | Journal article
DOI: 10.3389/fphar.2023.1076574
Part of ISSN: 1663-9812
Contributors: Lonneke J. Graansma; Qinglian Zhai; Loes Busscher; Roberta Menafra; Redmar R. van den Berg; Susan L. Kloet; Maaike van der Lee
Source: Self-asserted source
Susan Kloet

STRAIGHT-IN enables high-throughput targeting of large DNA payloads in human pluripotent stem cells

Cell Reports Methods
2022-10 | Journal article
DOI: 10.1016/j.crmeth.2022.100300
Part of ISSN: 2667-2375
Contributors: Albert Blanch-Asensio; Catarina Grandela; Karina O. Brandão; Tessa de Korte; Hailiang Mei; Yavuz Ariyurek; Loukia Yiangou; Mervyn P.H. Mol; Berend J. van Meer; Susan L. Kloet et al.
Source: Self-asserted source
Susan Kloet

Clostridioides difficilePCR ribotype 151 is polyphyletic and includes pathogenic isolates from cryptic clade C-II with mono-toxin pathogenicity loci that can escape routine diagnostics

2022-08-17 | Preprint
DOI: 10.1101/2022.08.17.504118
Contributors: Quinten R. Ducarmon; Tjomme van der Bruggen; Céline Harmanus; Ingrid M.J.G. Sanders; Laura G.M. Daenen; Ad C. Fluit; Rolf H.A.M. Vossen; Susan L. Kloet; Ed J. Kuijper; Wiep Klaas Smits
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Crossref

Carriage of three plasmids in a single human clinical isolate of Clostridioides difficile

2022-07-10 | Preprint
DOI: 10.1101/2022.07.10.499461
Contributors: Anna M. Roseboom; Quinten R. Ducarmon; B.V.H. Hornung; C. Harmanus; M.J.T. Crobach; Ed J. Kuijper; Rolf H.A.M. Vossen; Susan L. Kloet; Wiep Klaas Smits
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Crossref

Alternative Polyadenylation Utilization Results in Ribosome Assembly and mRNA Translation Deficiencies in a Model for Muscle Aging

The Journals of Gerontology: Series A
2022-06-01 | Journal article
DOI: 10.1093/gerona/glac058
Part of ISSN: 1079-5006
Part of ISSN: 1758-535X
Contributors: Hailiang Mei; Jasper Boom; Salma el Abdellaoui; Kotb Abdelmohsen; Rachel Munk; Jennifer L Martindale; Susan Kloet; Szymone M Kielbasa; Thomas H Sharp; Myriam Gorospe et al.
Source: Self-asserted source
Susan Kloet

Distinct mechanisms for genomic attachment of the 5′ and 3′ ends of Agrobacterium T-DNA in plants

Nature Plants
2022-05-09 | Journal article
DOI: 10.1038/s41477-022-01147-5
Contributors: Lejon E. M. Kralemann; Sylvia de Pater; Hexi Shen; Susan L. Kloet; Robin van Schendel; Paul J. J. Hooykaas; Marcel Tijsterman
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Crossref

p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models

Nature Genetics
2021-07-15 | Journal article
DOI: 10.1038/s41588-021-00893-0
Part of ISSN: 1061-4036
Part of ISSN: 1546-1718
Source: Self-asserted source
Susan Kloet

Differential regulation of lineage commitment in human and mouse primed pluripotent stem cells by the nucleosome remodelling and deacetylation complex

Stem cell research
2020 | Journal article
DOI: 10.1016/j.scr.2020.101867
Part of ISSN: 1873-5061
Source: Self-asserted source
Susan Kloet
grade
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The Genomes of the Livebearing Fish Species Poeciliopsis retropinna and Poeciliopsis turrubarensis Reflect Their Different Reproductive Strategies

Molecular biology and evolution
2020 | Journal article
DOI: 10.1093/molbev/msaa011
Part of ISSN: 0737-4038
Source: Self-asserted source
Susan Kloet
grade
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CACTUS: integrating clonal architecture with genomic clustering and transcriptome profiling of single tumor cells

2020-06-06 | Other
DOI: 10.1101/2020.06.05.134452
Contributors: Shadi Darvish Shafighi; Szymon M Kiełbasa; Julieta Sepúlveda-Yáñez; Ramin Monajemi; Davy Cats; Hailiang Mei; Roberta Menafra; Susan Kloet; Hendrik Veelken; Cornelis A.M. van Bergen et al.
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Crossref
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Estrogen Receptor Pathway Activity Score to Predict Clinical Response or Resistance to Neoadjuvant Endocrine Therapy in Primary Breast Cancer

Molecular Cancer Therapeutics
2020-02-01 | Journal article
DOI: 10.1158/1535-7163.MCT-19-0318
Contributors: Márcia A. Inda; Erik J. Blok; Peter J.K. Kuppen; Ayoub Charehbili; Eveline C. den Biezen-Timmermans; Anne van Brussel; Sevgi E. Fruytier; Elma Meershoek-Klein Kranenbarg; Susan Kloet; Bart van der Burg et al.
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Crossref
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Single-cell RNA sequencing in facioscapulohumeral muscular dystrophy disease etiology and development

Human molecular genetics
2019 | Journal article
DOI: 10.1093/hmg/ddy400
Part of ISSN: 0964-6906
Source: Self-asserted source
Susan Kloet
grade
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NuRD-interacting protein ZFP296 regulates genome-wide NuRD localization and differentiation of mouse embryonic stem cells

Nature communications
2018 | Journal article
DOI: 10.1038/s41467-018-07063-7
Part of ISSN: 2041-1723
Source: Self-asserted source
Susan Kloet
grade
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Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency

Cell Stem Cell
2018-11 | Journal article
DOI: 10.1016/j.stem.2018.10.017
Part of ISSN: 1934-5909
Contributors: Guido van Mierlo; René A.M. Dirks; Laura De Clerck; Arie B. Brinkman; Michelle Huth; Susan L. Kloet; Nehmé Saksouk; Leonie I. Kroeze; Sander Willems; Matthias Farlik et al.
Source: Self-asserted source
Susan Kloet via Crossref Metadata Search
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Sall4 controls differentiation of pluripotent cells independently of the Nucleosome Remodelling and Deacetylation (NuRD) complex

Development (Cambridge, England)
2016 | Journal article
DOI: 10.1242/dev.139113
Part of ISSN: 0950-1991
Source: Self-asserted source
Susan Kloet
grade
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The dynamic interactome and genomic targets of Polycomb complexes during stem-cell differentiation

Nature structural & molecular biology
2016 | Journal article
DOI: 10.1038/nsmb.3248
Part of ISSN: 1545-9993
Source: Self-asserted source
Susan Kloet
grade
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The Nucleosome Remodeling and Deacetylase Complex NuRD Is Built from Preformed Catalytically Active Sub-modules

Journal of molecular biology
2016 | Journal article
DOI: 10.1016/j.jmb.2016.04.025
Part of ISSN: 0022-2836
Source: Self-asserted source
Susan Kloet
grade
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Towards elucidating the stability, dynamics and architecture of the nucleosome remodeling and deacetylase complex by using quantitative interaction proteomics

FEBS Journal
2014-09-11 | Journal article
DOI: 10.1111/febs.12972
Part of ISSN: 1742-464X
Contributors: Susan L. Kloet; H. Irem Baymaz; Matthew Makowski; Vincent Groenewold; Pascal W. T. C. Jansen; Madeleine Berendsen; Hassin Niazi; Geert J. Kops; Michiel Vermeulen
Source: Self-asserted source
Susan Kloet via Crossref Metadata Search
grade
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Insight into the Architecture of the NuRD Complex

Journal of Biological Chemistry
2014-06-11 | Journal article
DOI: 10.1074/jbc.m114.558940
Part of ISSN: 0021-9258
Contributors: Saad S. M. Alqarni; Andal Murthy; Wei Zhang; Marcin R. Przewloka; Ana P. G. Silva; Aleksandra A. Watson; Sara Lejon; Xue Y. Pei; Arne H. Smits; Susan L. Kloet et al.
Source: Self-asserted source
Susan Kloet via Crossref Metadata Search
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Phosphorylation-Dependent Regulation of Cyclin D1 and Cyclin A Gene Transcription by TFIID Subunits TAF1 and TAF7

Molecular and Cellular Biology
2012-06 | Journal article
DOI: 10.1128/mcb.00416-12
Part of ISSN: 0270-7306
Contributors: S. L. Kloet; J. L. Whiting; P. Gafken; J. Ranish; E. H. Wang
Source: Self-asserted source
Susan Kloet via Crossref Metadata Search
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High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5

BMC Genetics
2010 | Journal article
DOI: 10.1186/1471-2156-11-106
Part of ISSN: 1471-2156
Contributors: Yung-Hao Ching; Robert J Munroe; Jennifer L Moran; Anna K Barker; Evan Mauceli; Tim Fennell; Frederica diPalma; Kerstin Lindblad-Toh; Lindsay M Abcunas; Joyanna F Gilmour et al.
Source: Self-asserted source
Susan Kloet via Crossref Metadata Search
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