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Employment (1)

Karolinska Institutet: Stockholm, Stockholm County, SE

2015-01-06 to present | Postdoctoral research Scientist (Department of Medicine Huddinge)
Employment
Source: Self-asserted source
Dara K. Mohammad

Education and qualifications (2)

Karolinska Institutet: Stockholm, Stockholm County, SE

2010-10-01 to present | Ph.D (Department of Medicine Huddinge)
Education
Source: Self-asserted source
Dara K. Mohammad

Salahaddin University-Erbil: Erbil, IQ

2004-11-01 to 2006-08-09 | M.Sc (Department of Biology)
Education
Source: Self-asserted source
Dara K. Mohammad

Works (33)

Antibody-displaying extracellular vesicles for targeted cancer therapy

Nature Biomedical Engineering
2024-05-20 | Journal article
DOI: 10.1038/s41551-024-01214-6
Contributors: Oscar P. B. Wiklander; Doste R. Mamand; Dara K. Mohammad; Wenyi Zheng; Rim Jawad Wiklander; Taras Sych; Antje M. Zickler; Xiuming Liang; Heena Sharma; Andrea Lavado et al.
Source: check_circle
Crossref

Tumor cell derived osteopontin and prostaglandin E2 synergistically promote the expansion of myeloid derived suppressor cells during the tumor immune escape phase

International Immunopharmacology
2024-03 | Journal article
DOI: 10.1016/j.intimp.2024.111584
Part of ISSN: 1567-5769
Contributors: Doste R Mamand; Safa Bazaz; Dara K. Mohammad; Osama Saher; Oscar P.B. Wiklander; Behnam Sadeghi; Moustapha Hassan; Samir EL-Andaloussi; Manuchehr Abedi-Valugerdi
Source: Self-asserted source
Dara K. Mohammad

Tumor cell derived osteopontin and prostaglandin E2 synergistically promote the expansion of myeloid derived suppressor cells during the tumor immune escape phase

OpenAlex
2024-03-01 | Other
DOI: 10.60692/17fhc-k0f45
Contributors: Doste R. Mamand; Safa Bazaz; Dara K. Mohammad; Osama Saher; Oscar Wiklander; Behnam Sadeghi; Mohamed Hasan; Samir El‐Andaloussi; Manuchehr Abedi‐Valugerdi
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DataCite

Tumor cell derived osteopontin and prostaglandin E2 synergistically promote the expansion of myeloid derived suppressor cells during the tumor immune escape phase

OpenAlex
2024-03-01 | Other
DOI: 10.60692/6x9t8-9eb40
Contributors: Doste R. Mamand; Safa Bazaz; Dara K. Mohammad; Osama Saher; Oscar Wiklander; Behnam Sadeghi; Mohamed Hasan; Samir El‐Andaloussi; Manuchehr Abedi‐Valugerdi
Source: check_circle
DataCite

SHP-1 localization to the activating immune synapse promotes NK cell tolerance in MHC class I deficiency

Science Signaling
2023-04-11 | Journal article
DOI: 10.1126/scisignal.abq0752
Contributors: Laurent Schmied; Thuy T. Luu; Jonas N. Søndergaard; Sophia H. Hald; Stephan Meinke; Dara K. Mohammad; Sunitha B. Singh; Corinna Mayer; Giovanna Perinetti Casoni; Michael Chrobok et al.
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Crossref

Assessment of T Cell Receptor Complex Expression Kinetics in Natural Killer Cells

Current Issues in Molecular Biology
2022-08-25 | Journal article
DOI: 10.3390/cimb44090265
Contributors: Khder H. Rasul; Alamdar Hussain; Hazel Reilly; Maria Karvouni; Carin I. M. Dahlberg; Mustafa S. Al-Attar; Arnika K. Wagner; Evren Alici; Dara K. Mohammad
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

BTK gatekeeper residue variation combined with cysteine 481 substitution causes super-resistance to irreversible inhibitors acalabrutinib, ibrutinib and zanubrutinib

Leukemia
2021-05 | Journal article
DOI: 10.1038/s41375-021-01123-6
Contributors: H. Yesid Estupiñán; Qing Wang; Anna Berglöf; Gerard C. P. Schaafsma; Yuye Shi; Litao Zhou; Dara K. Mohammad; Liang Yu; Mauno Vihinen; Rula Zain et al.
Source: check_circle
Crossref

Short-term IL-15 priming leaves a long-lasting signalling imprint in mouse NK cells independently of a metabolic switch

Life Science Alliance
2021-04 | Journal article
DOI: 10.26508/lsa.202000723
Contributors: Thuy T Luu; Laurent Schmied; Ngoc-Anh Nguyen; Clotilde Wiel; Stephan Meinke; Dara K Mohammad; Martin Bergö; Evren Alici; Nadir Kadri; Sridharan Ganesan et al.
Source: check_circle
Crossref

BTK gatekeeper residue variation combined with cysteine 481 substitution causes super-resistance to irreversible inhibitors acalabrutinib, ibrutinib and zanubrutinib

OpenAlex
2021-02-01 | Other
DOI: 10.60692/r707c-ga950
Contributors: H. Yesid Estupiñán; Qing Wang; Anna Berglöf; Gerard C. P. Schaafsma; YUYE SHI; Litao Zhou; Dara K. Mohammad; Liang Yu; Mauno Vihinen; Rula Zain et al.
Source: check_circle
DataCite

BTK gatekeeper residue variation combined with cysteine 481 substitution causes super-resistance to irreversible inhibitors acalabrutinib, ibrutinib and zanubrutinib

OpenAlex
2021-02-01 | Other
DOI: 10.60692/bx812-m1j61
Contributors: H. Yesid Estupiñán; Qing Wang; Anna Berglöf; Gerard C. P. Schaafsma; YUYE SHI; Litao Zhou; Dara K. Mohammad; Liang Yu; Mauno Vihinen; Rula Zain et al.
Source: check_circle
DataCite

Five insights from the Global Burden of Disease Study 2019.

Lancet (London, England)
2020-10-01 | Journal article
DOI: 10.1016/s0140-6736(20)31404-5
PMID: 33069324
PMC: PMC7116361
Source: Self-asserted source
Dara K. Mohammad

Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.

Lancet (London, England)
2020-08-27 | Journal article
DOI: 10.1016/s0140-6736(20)30750-9
PMID: 32861314
PMC: PMC7562819
Source: Self-asserted source
Dara K. Mohammad

The status of cancer publications in the Kurdistan region of Iraq

Journal of Cancer Policy
2020-06 | Journal article
DOI: 10.1016/j.jcpo.2020.100221
Part of ISSN: 2213-5383
Source: Self-asserted source
Dara K. Mohammad

The kidney injury caused by the onset of acute graft-versus-host disease is associated with down-regulation of αKlotho.

International immunopharmacology
2019-12-04 | Journal article
DOI: 10.1016/j.intimp.2019.106042
PMID: 31812067
Source: Self-asserted source
Dara K. Mohammad

Mapping 123 million neonatal, infant and child deaths between 2000 and 2017.

Nature
2019-10-16 | Journal article
DOI: 10.1038/s41586-019-1545-0
PMID: 31619795
PMC: PMC6800389
Source: Self-asserted source
Dara K. Mohammad

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study.

JAMA oncology
2019-09-27 | Journal article
DOI: 10.1001/jamaoncol.2019.2996
PMID: 31560378
PMC: PMC6777271
Source: Self-asserted source
Dara K. Mohammad

The global burden of childhood and adolescent cancer in 2017: an analysis of the Global Burden of Disease Study 2017.

The Lancet. Oncology
2019-07-29 | Journal article
DOI: 10.1016/S1470-2045(19)30339-0
PMID: 31371206
PMC: PMC6722045
Source: Self-asserted source
Dara K. Mohammad

Translocation-generated ITK-FER and ITK-SYK fusions induce STAT3 phosphorylation and CD69 expression

Biochemical and Biophysical Research Communications
2018-10 | Journal article
DOI: 10.1016/j.bbrc.2018.09.019
Contributors: Narmeen N. Fathi; Dara K. Mohammad; André Görgens; Samir EL. Andaloussi; Rula Zain; Beston F. Nore; C.I. Edvard Smith
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Crossref

Systematic Methodological Evaluation of a Multiplex Bead-Based Flow Cytometry Assay for Detection of Extracellular Vesicle Surface Signatures

Frontiers in Immunology
2018-06-20 | Journal article
Source: Self-asserted source
Dara K. Mohammad

ANKRD54 preferentially selects Bruton's Tyrosine Kinase (BTK) from a Human Src-Homology 3 (SH3) domain library.

PloS one
2017 | Journal article
DOI: 10.1371/journal.pone.0174909
PMID: 28369144
PMC: PMC5378395
Contributors: Gustafsson MO; Mohammad DK; Ylösmäki E; Choi H; Shrestha S; Wang Q; Nore BF; Saksela K; Smith CI
Source: Self-asserted source
Dara K. Mohammad via Europe PubMed Central

Terminating B cell receptor signaling.

Oncotarget
2017-12 | Journal article
DOI: 10.18632/oncotarget.22986
PMID: 29299112
PMC: PMC5746347
Contributors: Mohammad DK; Nore BF; Smith CIE
Source: Self-asserted source
Dara K. Mohammad via Europe PubMed Central

Substitution scanning identifies a novel, catalytically active ibrutinib-resistant BTK cysteine 481 to threonine (C481T) variant.

Leukemia
2017-01 | Journal article
DOI: 10.1038/leu.2016.153
PMID: 27282255
PMC: PMC5220130
Contributors: Hamasy A; Wang Q; Blomberg KE; Mohammad DK; Yu L; Vihinen M; Berglöf A; Smith CI
Source: Self-asserted source
Dara K. Mohammad via Europe PubMed Central

PRIMA-1 induces apoptosis of leukemic cells via inhibiting brutons tyrosine kinase

Cukurova Medical Journal, Volume 42, Number 1
2017-01-01 | Journal article
Source: Self-asserted source
Dara K. Mohammad

B Cell Receptor Activation Predominantly Regulates AKT-mTORC1/2 Substrates Functionally Related to RNA Processing.

PloS one
2016 | Journal article
DOI: 10.1371/journal.pone.0160255
PMID: 27487157
PMC: PMC4972398
Contributors: Mohammad DK; Ali RH; Turunen JJ; Nore BF; Smith CI
Source: Self-asserted source
Dara K. Mohammad via Europe PubMed Central

Protein kinase B (AKT) regulates SYK activity and shuttling through 14-3-3 and importin 7

The International Journal of Biochemistry & Cell Biology
2016-09 | Journal article
DOI: 10.1016/j.biocel.2016.06.024
Contributors: Dara K. Mohammad; Beston F. Nore; Manuela O. Gustafsson; Abdalla J. Mohamed; C.I. Edvard Smith
Source: check_circle
Crossref

Anti-leukaemic effects induced by APR-246 are dependent on induction of oxidative stress and the NFE2L2/HMOX1 axis that can be targeted by PI3K and mTOR inhibitors in acute myeloid leukaemia cells.

British journal of haematology
2016-07 | Journal article
DOI: 10.1111/bjh.14036
PMID: 26991755
Contributors: Ali D; Mohammad DK; Mujahed H; Jonson-Videsäter K; Nore B; Paul C; Lehmann S
Source: Self-asserted source
Dara K. Mohammad via Europe PubMed Central

Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model.

The Journal of clinical investigation
2014-09 | Journal article
DOI: 10.1172/jci76175
PMID: 25105368
PMC: PMC4151202
Contributors: Bestas B; Moreno PM; Blomberg KE; Mohammad DK; Saleh AF; Sutlu T; Nordin JZ; Guterstam P; Gustafsson MO; Kharazi S et al.
Source: Self-asserted source
Dara K. Mohammad via Europe PubMed Central

Dual phosphorylation of Btk by Akt/protein kinase b provides docking for 14-3-3ζ, regulates shuttling, and attenuates both tonic and induced signaling in B cells.

Molecular and cellular biology
2013-08 | Journal article
DOI: 10.1128/mcb.00247-13
PMID: 23754751
PMC: PMC3753922
Contributors: Mohammad DK; Nore BF; Hussain A; Gustafsson MO; Mohamed AJ; Smith CI
Source: Self-asserted source
Dara K. Mohammad via Europe PubMed Central

Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK (spleen tyrosine kinase) fusion kinase is dependent on adapter SLP-76 and on the adapter function of the kinases SYK and ZAP70.

The Journal of biological chemistry
2013-03 | Journal article
DOI: 10.1074/jbc.m112.374967
PMID: 23293025
PMC: PMC3591642
Contributors: Hussain A; Mohammad DK; Gustafsson MO; Uslu M; Hamasy A; Nore BF; Mohamed AJ; Smith CI
Source: Self-asserted source
Dara K. Mohammad via Europe PubMed Central

Regulation of nucleocytoplasmic shuttling of Bruton's tyrosine kinase (Btk) through a novel SH3-dependent interaction with ankyrin repeat domain 54 (ANKRD54).

Molecular and cellular biology
2012-07 | Journal article
DOI: 10.1128/mcb.06620-11
PMID: 22527282
PMC: PMC3434478
Contributors: Gustafsson MO; Hussain A; Mohammad DK; Mohamed AJ; Nguyen V; Metalnikov P; Colwill K; Pawson T; Smith CI; Nore BF
Source: Self-asserted source
Dara K. Mohammad via Europe PubMed Central

TEC family kinases in health and disease--loss-of-function of BTK and ITK and the gain-of-function fusions ITK-SYK and BTK-SYK.

The FEBS journal
2011-06 | Journal article
DOI: 10.1111/j.1742-4658.2011.08134.x
PMID: 21518255
Contributors: Hussain A; Yu L; Faryal R; Mohammad DK; Mohamed AJ; Smith CI
Source: Self-asserted source
Dara K. Mohammad via Europe PubMed Central

Effects of erythropoietin and growth hormone on hematological and biochemical parameters in 5/6 nephrectomized male albino rats

J Duhuk Univ (12;1), 146-160
2009 | Journal article
Source: Self-asserted source
Dara K. Mohammad

Effect of Hemodialysis and Peritoneal Dialysis on some Hematological and Biochemical Parameters in Renal Failure

Zanco J. Med. Sc
2008-11-05 | Journal article
Source: Self-asserted source
Dara K. Mohammad

Peer review (6 reviews for 4 publications/grants)

Review activity for Cancers. (2)
Review activity for Cells. (1)
Review activity for International journal of molecular sciences. (2)
Review activity for Saudi pharmaceutical journal. (1)
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