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Scopus Author ID: 56940917500

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Professional activities (1)

Royal Society of Biology: London, GB

2023-01-05 to present | MRSB
Membership
Source: Self-asserted source
Kathryn Crouch

Funding (2)

Byte-sized bioinformatics: introducing Big Data through computational biology

2020-02-10 to 2020-11-09 | Grant
Science and Technology Facilities Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.8856274
GRANT_NUMBER: ST/T000872/1
Source: Self-asserted source
Kathryn Crouch via DimensionsWizard

Bioinformatics resources for kinetoplastid organisms and their hosts

2020-01 to 2024-12 | Grant
Wellcome Trust (London, GB)
Part of GRANT_NUMBER:

218288/Z/19/Z
Source: Self-asserted source
Kathryn Crouch

Works (38)

MFAseq data processing script

Zenodo
2025-04-01 | Other
DOI: 10.5281/zenodo.14224854
Contributors: Kathryn Crouch
Source: check_circle
DataCite

MFAseq data processing script

Zenodo
2025-04-01 | Other
DOI: 10.5281/zenodo.15118860
Contributors: Kathryn Crouch
Source: check_circle
DataCite
grade
Preferred source (of 2)‎

paraCell: a novel software tool for the interactive analysis and visualization of standard and dual host–parasite single-cell RNA-seq data

Nucleic Acids Research
2025-02-08 | Journal article
DOI: 10.1093/nar/gkaf091
Contributors: Edward Agboraw; William Haese-Hill; Franziska Hentzschel; Emma Briggs; Dana Aghabi; Anna Heawood; Clare R Harding; Brian Shiels; Kathryn Crouch; Domenico Somma et al.
Source: check_circle
Crossref

Nanopore sequencing reveals that DNA replication compartmentalisation dictates genome stability and instability in Trypanosoma brucei

Nature Communications
2025-01-16 | Journal article
DOI: 10.1038/s41467-025-56087-3
Contributors: Marija Krasiļņikova; Catarina A. Marques; Emma M. Briggs; Craig Lapsley; Graham Hamilton; Dario Beraldi; Kathryn Crouch; Richard McCulloch
Source: check_circle
Crossref

TransLeish: Identification of membrane transporters essential for survival of intracellular Leishmania parasites in a systematic gene deletion screen

Nature Communications
2025-01-02 | Journal article
DOI: 10.1038/s41467-024-55538-7
Contributors: Andreia Albuquerque-Wendt; Ciaran McCoy; Rachel Neish; Ulrich Dobramysl; Çağla Alagöz; Tom Beneke; Sally A. Cowley; Kathryn Crouch; Richard J. Wheeler; Jeremy C. Mottram et al.
Source: check_circle
Crossref

MFAseq data processing script

Zenodo
2024-11-26 | Other
DOI: 10.5281/zenodo.14224855
Contributors: Kathryn Crouch
Source: check_circle
DataCite

paraCell: A novel software tool for the interactive analysis and visualization of standard and dual host-parasite single cell RNA-Seq data

2024-08-30 | Preprint
DOI: 10.1101/2024.08.29.610375
Contributors: Edward Agboraw; William Haese-Hill; Franziska Hentzschel; Emma Marie Briggs; Dana Aghabi; Anna Heawood; Clare R Harding; Brian Schiels; Kathryn R Crouch; Domenico Somma et al.
Source: check_circle
Crossref

TransLeish: Identification of membrane transporters essential for survival of intracellularLeishmaniaparasites in a systematic gene deletion screen

2024-06-25 | Preprint
DOI: 10.1101/2024.06.21.600025
Contributors: Andreia Albuquerque-Wendt; Ciaran McCoy; Rachel Neish; Ulrich Dobramysl; Tom Beneke; Sally A. Cowley; Kathryn Crouch; Richard J. Wheeler; Jeremy C. Mottram; Eva Gluenz
Source: check_circle
Crossref

Nanopore sequencing reveals that DNA replication compartmentalisation dictates genome stability and instability inTrypanosoma brucei

2024-05-07 | Preprint
DOI: 10.1101/2024.05.07.592375
Contributors: Marija Krasiļņikova; Catarina A. Marques; Emma M. Briggs; Craig Lapsley; Graham Hamilton; Dario Beraldi; Kathryn Crouch; Richard McCulloch
Source: check_circle
Crossref

What is new in FungiDB: a web-based bioinformatics platform for omics-scale data analysis for fungal and oomycete species

GENETICS
2024-05-07 | Journal article
DOI: 10.1093/genetics/iyae035
Contributors: Evelina Y Basenko; Achchuthan Shanmugasundram; Ulrike Böhme; David Starns; Paul A Wilkinson; Helen R Davison; Kathryn Crouch; Gareth Maslen; Omar S Harb; Beatrice Amos et al.
Source: check_circle
Crossref

Annotation and visualisation of parasite, fungi and arthropod genomes with Companion

2024-02-21 | Preprint
DOI: 10.1101/2024.02.19.580948
Contributors: William Haese-Hill; Kathryn Crouch; Thomas D. Otto
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Genomic diversity of novel strains of mammalian gut microbiome derivedClostridiumXIVa strains is driven by mobile genetic element acquisition

2024-01-23 | Preprint
DOI: 10.1101/2024.01.22.576618
Contributors: Maya T. Kamat; Michael J. Ormsby; Suzanne Humphrey; Shivendra Dixit; Katja Thümmler; Craig Lapsley; Kathryn Crouch; Caitlin Jukes; Heather Hulme; Richard Burchmore et al.
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center in 2023.

Nucleic acids research
2024-01-01 | Journal article | Author
DOI: 10.1093/nar/gkad1003
PMID: 37953350
PMC: PMC10767879
Contributors: Alvarez-Jarreta J; Amos B; Aurrecoechea C; Saikou Y Bah; Barba M; Barreto A; Basenko EY; Belnap R; Blevins A; Böhme U et al.
Source: Self-asserted source
Kathryn Crouch

Improved eukaryotic detection compatible with large-scale automated analysis of metagenomes.

Microbiome
2023-04-10 | Journal article
DOI: 10.1101/2022.03.09.483664
DOI: 10.1186/s40168-023-01505-1
PMID: 37032329
PMC: PMC10084625
Contributors: Bazant W; Blevins AS; Crouch K; Beiting DP
Source: Self-asserted source
Kathryn Crouch
grade
Preferred source (of 3)‎

peaks2utr: a robust Python tool for the annotation of 3′ UTRs

Bioinformatics
2023-03-01 | Journal article
DOI: 10.1093/bioinformatics/btad112
Contributors: William Haese-Hill; Kathryn Crouch; Thomas D Otto; Tobias Marschall
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

TriTrypDB: An integrated functional genomics resource for kinetoplastida.

PLoS neglected tropical diseases
2023-01-19 | Journal article
DOI: 10.1371/journal.pntd.0011058
PMID: 36656904
PMC: PMC9888696
Contributors: Shanmugasundram A; Starns D; Böhme U; Amos B; Wilkinson PA; Harb OS; Warrenfeltz S; Kissinger JC; McDowell MA; Roos DS et al.
Source: Self-asserted source
Kathryn Crouch

Bringing bioinformatics to schools with the 4273pi project

PLOS Computational Biology
2022-01-20 | Journal article
DOI: 10.1371/journal.pcbi.1009705
Contributors: Stevie A. Bain; Francis Ouellette; Heleen Plaisier; Felicity Anderson; Nicola Cook; Kathryn Crouch; Thomas R. Meagher; Michael G. Ritchie; Edward W. J. Wallace; Daniel Barker
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center.

Nucleic acids research
2022-01-01 | Journal article
DOI: 10.1093/nar/gkab929
PMID: 34718728
PMC: PMC8728164
Source: Self-asserted source
Kathryn Crouch
grade
Preferred source (of 3)‎

Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole

PLOS Neglected Tropical Diseases
2021-11-09 | Journal article
DOI: 10.1371/journal.pntd.0009939
Contributors: Pieter C. Steketee; Margaret A. Phillips; Federica Giordani; Isabel M. Vincent; Kathryn Crouch; Fiona Achcar; Nicholas J. Dickens; Liam J. Morrison; Annette MacLeod; Michael P. Barrett
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Widespread roles of Trypanosoma brucei ATR in nuclear genome function and transmission are linked to R-loops

2021-09-09 | Other
DOI: 10.1101/2021.09.09.459654
Contributors: J.A. Black; K. Crouch; E. Briggs; L. Lemgruber; C. Lapsely; L. R. O. Tosi; J. C. Mottram; R. McCulloch
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition

PLOS Pathogens
2021-07-26 | Journal article
DOI: 10.1371/journal.ppat.1009734
Contributors: Pieter C. Steketee; Christine Clayton; Emily A. Dickie; James Iremonger; Kathryn Crouch; Edith Paxton; Siddharth Jayaraman; Omar A. Alfituri; Georgina Awuah-Mensah; Ryan Ritchie et al.
Source: check_circle
Crossref
grade
Preferred source (of 6)‎

Next-Generation Analysis of Trypanosomatid Genome Stability and Instability

Methods in Molecular Biology
2020 | Book chapter
DOI: 10.1007/978-1-0716-0294-2_15
EID:

2-s2.0-85082513019

Part of ISSN: 19406029 10643745
Contributors: Briggs, E.M.; Marques, C.A.; Reis-Cunha, J.; Black, J.; Campbell, S.; Damasceno, J.; Bartholomeu, D.; Crouch, K.; McCulloch, R.
Source: Self-asserted source
Kathryn Crouch via Scopus - Elsevier
grade
Preferred source (of 2)‎

Genome duplication in Leishmania major relies on persistent subtelomeric DNA replication

eLife
2020-09-08 | Journal article
DOI: 10.7554/eLife.58030
Contributors: Jeziel Dener Damasceno; Catarina A Marques; Dario Beraldi; Kathryn Crouch; Craig Lapsley; Ricardo Obonaga; Luiz RO Tosi; Richard McCulloch
Source: check_circle
Crossref
grade
Preferred source (of 6)‎

Conditional knockout of RAD51-related genes in Leishmania major reveals a critical role for homologous recombination during genome replication

PLOS Genetics
2020-07-01 | Journal article
DOI: 10.1371/journal.pgen.1008828
Contributors: Jeziel D. Damasceno; Marc Ouellette; João Reis-Cunha; Kathryn Crouch; Dario Beraldi; Craig Lapsley; Luiz R. O. Tosi; Daniella Bartholomeu; Richard McCulloch
Source: check_circle
Crossref
grade
Preferred source (of 6)‎

Trypanosoma brucei ATR Links DNA Damage Signaling during Antigenic Variation with Regulation of RNA Polymerase I-Transcribed Surface Antigens.

Cell reports
2020-01-01 | Journal article
DOI: 10.1101/435198
DOI: 10.1016/j.celrep.2019.12.049
PMID: 31968257
PMC: PMC6988115
Source: Self-asserted source
Kathryn Crouch
grade
Preferred source (of 5)‎

Trypanosoma brucei ribonuclease H2A is an essential R-loop processing enzyme whose loss causes DNA damage during transcription initiation and antigenic variation.

Nucleic acids research
2019-09 | Journal article
DOI: 10.1093/nar/gkz644
PMID: 31350892
Contributors: Briggs E; Crouch K; Lemgruber L; Hamilton G; Lapsley C; McCulloch R
Source: Self-asserted source
Kathryn Crouch via Europe PubMed Central
grade
Preferred source (of 6)‎

Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target.

Science (New York, N.Y.)
2019-08 | Journal article
DOI: 10.1126/science.aau1682
PMID: 31467193
Contributors: Alam MM; Sanchez-Azqueta A; Janha O; Flannery EL; Mahindra A; Mapesa K; Char AB; Sriranganadane D; Brancucci NMB; Antonova-Koch Y et al.
Source: Self-asserted source
Kathryn Crouch via Europe PubMed Central
grade
Preferred source (of 6)‎

Ribonuclease H1-targeted R-loops in surface antigen gene expression sites can direct trypanosome immune evasion

PLOS Genetics
2018-12-13 | Journal article
DOI: 10.1371/journal.pgen.1007729
Contributors: Emma Briggs; Nancy Maizels; Kathryn Crouch; Leandro Lemgruber; Craig Lapsley; Richard McCulloch
Source: check_circle
Crossref
grade
Preferred source (of 6)‎

A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasis

EBioMedicine
2018-10 | Journal article
DOI: 10.1016/j.ebiom.2018.09.029
Contributors: Juliana B.T. Carnielli; Kathryn Crouch; Sarah Forrester; Vladimir Costa Silva; Sílvio F.G. Carvalho; Jeziel D. Damasceno; Elaine Brown; Nicholas J. Dickens; Dorcas L. Costa; Carlos H.N. Costa et al.
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Genome-wide mapping reveals conserved and diverged R-loop activities in the unusual genetic landscape of the African trypanosome genome

Nucleic Acids Research
2018-10-10 | Journal article
DOI: 10.1101/357020
DOI: 10.1093/nar/gky928
Source: Self-asserted source
Kathryn Crouch
grade
Preferred source (of 5)‎

FungiDB: An Integrated Bioinformatic Resource for Fungi and Oomycetes.

Journal of fungi (Basel, Switzerland)
2018-03-20 | Journal article
DOI: 10.3390/jof4010039
PMID: 30152809
PMC: PMC5872342
Source: Self-asserted source
Kathryn Crouch
grade
Preferred source (of 5)‎

EuPathDB: The Eukaryotic Pathogen Genomics Database Resource.

Methods in molecular biology (Clifton, N.J.)
2018-01 | Journal article
DOI: 10.1007/978-1-4939-7737-6_5
PMID: 29761457
Contributors: Warrenfeltz S; Basenko EY; Crouch K; Harb OS; Kissinger JC; Roos DS; Shanmugasundram A; Silva-Franco F
Source: Self-asserted source
Kathryn Crouch via Europe PubMed Central
grade
Preferred source (of 4)‎

Protozoan parasite genomics

Molecular Parasitology: Genomes, Proteomes, Glycomes and Lipidomes
2016 | Book chapter
Source: Self-asserted source
Kathryn Crouch

EuPathDB: the eukaryotic pathogen genomics database resource.

Nucleic acids research
2016-11-29 | Journal article
DOI: 10.1093/nar/gkw1105
PMID: 27903906
PMC: PMC5210576
Source: Self-asserted source
Kathryn Crouch
grade
Preferred source (of 5)‎

TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei

Nucleic Acids Research
2015 | Journal article
DOI: 10.1093/nar/gku944
Source: Self-asserted source
Kathryn Crouch
grade
Preferred source (of 3)‎

Corrigendum to "Humoral immune response of the small-spotted catshark, Scyliorhinus canicula" [Fish Shellfish Immunol 34, (2013) 1158-1169]

Fish and Shellfish Immunology
2013 | Journal article
DOI: 10.1016/j.fsi.2013.05.011
EID:

2-s2.0-84890739897

Part of ISSN: 10959947 10504648
Contributors: Crouch, K.; Smith, L.E.; Williams, R.; Cao, W.; Lee, M.; Jensen, A.; Dooley, H.
Source: Self-asserted source
Kathryn Crouch via Scopus - Elsevier
grade
Preferred source (of 2)‎

Humoral immune response of the small-spotted catshark, Scyliorhinus canicula

Fish and Shellfish Immunology
2013 | Journal article
DOI: 10.1016/j.fsi.2013.01.025
Source: Self-asserted source
Kathryn Crouch
grade
Preferred source (of 3)‎

Characterization of the immunoglobulin repertoire of the spiny dogfish (Squalus acanthias)

Developmental and Comparative Immunology
2012 | Journal article
DOI: 10.1016/j.dci.2011.10.007
Source: Self-asserted source
Kathryn Crouch
grade
Preferred source (of 3)‎

Peer review (1 review for 1 publication/grant)

Review activity for Nucleic acids research. (1)
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