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Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog pathway inhibitor-1

Nature Communications
2023-07-01 | Journal article
DOI: 10.1038/s41467-023-39657-1
Contributors: Meropi Bagka; Hyeonyi Choi; Margaux Héritier; Hanna Schwaemmle; Quentin T. L. Pasquer; Simon M. G. Braun; Leonardo Scapozza; Yibo Wu; Sascha Hoogendoorn
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Photocleavable Fluorescent Membrane Tension Probes: Fast Release with Spatiotemporal Control in Inner Leaflets of Plasma Membrane, Nuclear Envelope, and Secretory Pathway

Angewandte Chemie
2022-01-03 | Journal article
DOI: 10.1002/ange.202113163
Contributors: Javier López‐Andarias; Krikor Eblighatian; Quentin T. L. Pasquer; Lea Assies; Naomi Sakai; Sascha Hoogendoorn; Stefan Matile
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From Phenotypic Hit to Chemical Probe: Chemical Biology Approaches to Elucidate Small Molecule Action in Complex Biological Systems

Molecules
2020-12-03 | Journal article
DOI: 10.3390/molecules25235702
Contributors: Quentin T. L. Pasquer; Ioannis A. Tsakoumagkos; Sascha Hoogendoorn
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