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Employment (1)

Institute of Biophysics Chinese Academy of Sciences: Chaoyang District, Beijing, CN

2011-02-01 to present | Associate Professor
Employment
Source: Self-asserted source
Yun Zhu

Education and qualifications (1)

Tsinghua University: Beijing, Beijing, CN

2006-09-01 to 2011-01-01 | Ph.D
Qualification
Source: Self-asserted source
Yun Zhu

Works (37)

Nanometer resolution in situ structure of SARS-CoV-2 post-fusion spike

2021 | Journal article
Source: Self-asserted source
Yun Zhu

Pan-coronavirus fusion inhibitors as the hope for today and tomorrow

Protein & cell
2021 | Journal article
Source: Self-asserted source
Yun Zhu

Repurposing of a clinically used anti-HPV agent to prevent and treat SARS-CoV-2 infection as an intranasal formulation

Signal transduction and targeted therapy
2021 | Journal article
Source: Self-asserted source
Yun Zhu

Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation

Signal transduction and targeted therapy
2021 | Journal article
Source: Self-asserted source
Yun Zhu

The Unusual Homodimer of a Heme-Copper Terminal Oxidase Allows Itself to Utilize Two Electron Donors

Angewandte Chemie International Edition
2021 | Journal article
Source: Self-asserted source
Yun Zhu

VHUT-cryo-FIB, a method to fabricate frozen hydrated lamellae from tissue specimens for in situ cryo-electron tomography

Journal of Structural Biology
2021 | Journal article
Source: Self-asserted source
Yun Zhu

Repurposing of a clinically used anti-HPV agent to prevent and treat SARS-CoV-2 infection as an intranasal formulation.

Signal transduction and targeted therapy
2021-08 | Journal article
DOI: 10.1038/s41392-021-00737-7
PMID: 34446694
PMC: PMC8390030
Contributors: Hua C; Ma Q; Zhu Y; Xia S; Liu Z; Li L; Lu L; Zhong N; Liu S; Yang Z et al.
Source: Self-asserted source
Yun Zhu via Europe PubMed Central

A 3.3 Å-Resolution Structure of Hyperthermophilic Respiratory Complex III Reveals the Mechanism of Its Thermal Stability

Angewandte Chemie
2020 | Journal article
Source: Self-asserted source
Yun Zhu

An amphipathic peptide targeting the gp41 cytoplasmic tail kills HIV-1 virions and infected cells

Science Translational Medicine
2020 | Journal article
Source: Self-asserted source
Yun Zhu

CALCIUM-DEPENDENT PROTEIN KINASE 32-mediated phosphorylation is essential for the ammonium transport activity of AMT1; 1 in Arabidopsis roots

Journal of experimental botany
2020 | Journal article
Source: Self-asserted source
Yun Zhu

Frontispiece: A 3.3 Å-Resolution Structure of Hyperthermophilic Respiratory Complex III Reveals the Mechanism of Its Thermal Stability

Angewandte Chemie International Edition
2020 | Journal article
Source: Self-asserted source
Yun Zhu

Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein

Cellular & molecular immunology
2020 | Journal article
Source: Self-asserted source
Yun Zhu

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

Cell research
2020 | Journal article
Source: Self-asserted source
Yun Zhu

Intravaginal administration of human type III collagen-derived biomaterial with high cell-adhesion activity to treat vaginal atrophy in rats

ACS Biomaterials Science & Engineering
2020 | Journal article
Source: Self-asserted source
Yun Zhu

Minireview of progress in the structural study of SARS-CoV-2 proteins

Current research in microbial sciences
2020 | Journal article
Source: Self-asserted source
Yun Zhu

The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin

Signal transduction and targeted therapy
2020 | Journal article
Source: Self-asserted source
Yun Zhu

Characterization by high-resolution crystal structure analysis of a triple-helix region of human collagen type III with potent cell adhesion activity

Biochemical and biophysical research communications
2019 | Journal article
Source: Self-asserted source
Yun Zhu

Crystal structure of refolding fusion core of Lassa virus GP2 and design of Lassa virus fusion inhibitors

Frontiers in microbiology
2019 | Journal article
Source: Self-asserted source
Yun Zhu

The underlying mechanism of 3-hydroxyphthalic anhydride-modified bovine beta-lactoglobulin to block human papillomavirus entry into the host cell

Frontiers in microbiology
2019 | Journal article
Source: Self-asserted source
Yun Zhu

Structure of a prokaryotic SEFIR domain reveals two novel SEFIR-SEFIR interaction modes

Journal of structural biology
2018 | Journal article
Source: Self-asserted source
Yun Zhu

Structure of the DNA-binding domain of human myelin-gene regulatory factor reveals its potential protein-DNA recognition mode

Journal of structural biology
2018 | Journal article
Source: Self-asserted source
Yun Zhu

A novel HIV-1 gp41 tripartite model for rational design of HIV-1 fusion inhibitors with improved antiviral activity

Aids
2017 | Journal article
Source: Self-asserted source
Yun Zhu

A novel mutation in the pyrin domain of the NOD-like receptor family pyrin domain containing protein 3 in Muckle-Wells syndrome

Chinese medical journal
2017 | Journal article
Source: Self-asserted source
Yun Zhu

Creating an artificial tail anchor as a novel strategy to enhance the potency of peptide-based HIV fusion inhibitors

Journal of virology
2017 | Journal article
Source: Self-asserted source
Yun Zhu

An immunogen containing four tandem 10E8 epitope repeats with exposed key residues induces antibodies that neutralize HIV-1 and activates an ADCC reporter gene

Emerging microbes & infections
2016 | Journal article
Source: Self-asserted source
Yun Zhu

Rational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations

Scientific reports
2016 | Journal article
Source: Self-asserted source
Yun Zhu

Safety evaluation of chemically modified beta-lactoglobulin administered intravaginally

Journal of medical virology
2016 | Journal article
Source: Self-asserted source
Yun Zhu

Structure of iridoid synthase in complex with NADP+/8-oxogeranial reveals the structural basis of its substrate specificity

Journal of structural biology
2016 | Journal article
Source: Self-asserted source
Yun Zhu

Improved pharmacological and structural properties of HIV fusion inhibitor AP3 over enfuvirtide: highlighting advantages of artificial peptide strategy

Scientific reports
2015 | Journal article
Source: Self-asserted source
Yun Zhu

Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor

Nature communications
2014 | Journal article
Source: Self-asserted source
Yun Zhu

Identification of a human protein-derived HIV-1 fusion inhibitor targeting the gp41 fusion core structure

PLoS One
2013 | Journal article
Source: Self-asserted source
Yun Zhu

Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement

Protein & cell
2013 | Journal article
Source: Self-asserted source
Yun Zhu

Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation

Protein & cell
2012 | Journal article
Source: Self-asserted source
Yun Zhu

Identification of a gp41 core-binding molecule with homologous sequence of human TNNI3K-like protein as a novel human immunodeficiency virus type 1 entry inhibitor

Journal of virology
2010 | Journal article
Source: Self-asserted source
Yun Zhu

Surface exposure of the HIV-1 env cytoplasmic tail LLP2 domain during the membrane fusion process: interaction with gp41 fusion core

Journal of Biological Chemistry
2008 | Journal article
Source: Self-asserted source
Yun Zhu

V3 CTL epitope density in a single recombinant molecule antigen differentially affects the number and activity of primary and memory CD8+ T cells

Vaccine
2008 | Journal article
Source: Self-asserted source
Yun Zhu

Important Changes in Biochemical Properties and Function of Mutated LLP12 Domain of HIV-1 gp41

Chemical biology & drug design
2007 | Journal article
Source: Self-asserted source
Yun Zhu
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