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You-Qiang Song

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Scopus Author ID: 55812396800

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Employment (1)

University of Hong Kong: Hong Kong, HK

2013-07-01 to present | Associate Professor (School of Biomedical Sciences)
Employment
Source: Self-asserted source
You-Qiang Song

Education and qualifications (1)

University of Reading: Reading, Berkshire, GB

PhD (Department of Biochemistry and Physiology)
Education
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You-Qiang Song

Works (50 of 178)

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Page 1 of 4

Lower expression of BIN1's neuronal isoform in vulnerable excitatory neurons increases risk in Alzheimer's disease

Journal of Alzheimer's Disease Reports
2025-01 | Journal article
DOI: 10.1177/25424823241296018
Contributors: Rajesh Ranganathan; Siwen Li; Georgy Sapozhnikov; Shoutang Wang; You-Qiang Song
Source: check_circle
Crossref

Cerebrospinal Fluid Dynamics: Uncovering Alternative Blood Vessel Clearance Mechanisms

2024-06-19 | Preprint
DOI: 10.21203/rs.3.rs-4573318/v1
Contributors: Qiuju Yuan; Senthil Kumaran Satyanarayanan; Suki Man-Yan Lee; Lingli Yan; Yaofeng Wang; Yan-Fang Xian; Liumin He; Yingying Zhou; Wutian Wu; You-Qiang Song et al.
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Cerebrospinal Fluid Dynamics: Uncovering Alternative Blood Vessel Clearance Mechanisms

2024-06-14 | Preprint
DOI: 10.1101/2024.06.13.598807
Contributors: Qiuju Yuan; Senthil Kumaran Satyanarayanan; Suki Man-Yan Lee; Lingli Yan; Yaofeng Wang; Yan-Fang Xian; Liumin He; Yingying Zhou; Wutian Wu; You-Qiang Song et al.
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Core planar cell polarity genes <i>VANGL1</i> and <i>VANGL2</i> in predisposition to congenital vertebral malformations

Proceedings of the National Academy of Sciences
2024-04-26 | Journal article | Author
DOI: 10.1073/pnas.2310283121
Part of ISSN: 1091-6490
Contributors: Xin Feng; Yongyu Ye; Jianan Zhang; Yuanqiang Zhang; Sen Zhao; Judith Mak; Nao Otomo; Zhengye Zhao; Yuchen Niu; Yoshiro Yonezawa et al.
Source: Self-asserted source
You-Qiang Song via Crossref Metadata Search

Enhancing the efficacy of vaccinia-based oncolytic virotherapy by inhibiting CXCR2-mediated MDSC trafficking

Journal of Leukocyte Biology
2024-03-29 | Journal article
DOI: 10.1093/jleuko/qiad150
Contributors: Zhiwu Tan; Mei Sum Chiu; Ming Yue; Hau Yee Kwok; Man Ho Tse; Yang Wen; Bohao Chen; Dawei Yang; Dongyan Zhou; You-Qiang Song et al.
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Crossref

Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis

eLife
2024-01-26 | Journal article | Author
DOI: 10.7554/elife.89762.4
Part of ISSN: 2050-084X
Contributors: Hao Yu; Anas M Khanshour; Aki Ushiki; Nao Otomo; Yoshinao Koike; Elisabet Einarsdottir; Yanhui Fan; Lilian Antunes; Yared H Kidane; Reuel Cornelia et al.
Source: Self-asserted source
You-Qiang Song via Crossref Metadata Search

Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis

eLife
2024-01-26 | Journal article | Author
DOI: 10.7554/elife.89762
Part of ISSN: 2050-084X
Contributors: Hao Yu; Anas M Khanshour; Aki Ushiki; Nao Otomo; Yoshinao Koike; Elisabet Einarsdottir; Yanhui Fan; Lilian Antunes; Yared H Kidane; Reuel Cornelia et al.
Source: Self-asserted source
You-Qiang Song via Crossref Metadata Search

Recent developments in the role of DNA damage response and understanding its implications for new therapeutic approaches in Alzheimer's disease

Translational Medicine of Aging
2023 | Journal article
DOI: 10.1016/j.tma.2023.06.004
Contributors: Rajesh Ranganathan; Georgy Sapozhnikov; Wang Ni; Siwen Li; Youqiang Song
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Crossref

Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy

Journal of Ginseng Research
2023-05 | Journal article
DOI: 10.1016/j.jgr.2022.12.001
Part of ISSN: 1226-8453
Contributors: Ni Wang; Junyan Yang; Ruijun Chen; Yunyun Liu; Shunjie Liu; Yining Pan; Qingfeng Lei; Yuzhou Wang; Lu He; Youqiang Song et al.
Source: Self-asserted source
You-Qiang Song

Analogous comparison unravels heightened antiviral defense and boosted viral infection upon immunosuppression in bat organoids

Signal Transduction and Targeted Therapy
2022-12-19 | Journal article
DOI: 10.1038/s41392-022-01247-w
Part of ISSN: 2059-3635
Contributors: Xiaojuan Liu; Cun Li; Zhixin Wan; Man Chun Chiu; Jingjing Huang; Yifei Yu; Lin Zhu; Jian-Piao Cai; Lei Rong; You-qiang Song et al.
Source: Self-asserted source
You-Qiang Song via Crossref Metadata Search

Isoformic PD-1-mediated immunosuppression underlies resistance to PD-1 blockade in hepatocellular carcinoma patients

Gut
2022-11-30 | Journal article
DOI: 10.1136/gutjnl-2022-327133
Part of ISSN: 1468-3288
Contributors: Zhiwu Tan; Mei Sum Chiu; Xinxiang Yang; Ming Yue; Tan To Cheung; Dongyan Zhou; Yuewen Wang; Anthony Wing-Hung Chan; Chi Wing Yan; Ka Yi Kwan et al.
Source: Self-asserted source
You-Qiang Song via Crossref Metadata Search

Mitochondrial regulation of acute extrafollicular B‐cell responses to COVID‐19 severity

Clinical and Translational Medicine
2022-09 | Journal article
DOI: 10.1002/ctm2.1025
Part of ISSN: 2001-1326
Contributors: Tianyu Cao; Liu, L; Kelvin Kai‐Wang To; Chun‐Yu Lim; Runhong Zhou; Yue Ming; Ka‐Yi Kwan; Sulan Yu; Chun‐Yin Chan; Biao Zhou et al.
Source: Self-asserted source
You-Qiang Song via Crossref Metadata Search

Distribution and inter-regional relationship of amyloid-beta plaque deposition in a 5xFAD mouse model of Alzheimer’s disease

Frontiers in Aging Neuroscience
2022-07-28 | Journal article
DOI: 10.3389/fnagi.2022.964336
Part of ISSN: 1663-4365
Contributors: Ka Chun Tsui; Jaydeep Roy; Sze Chun Chau; Kah Hui Wong; Lei Shi; Chi Him Poon; Yingyi Wang; Tatyana Strekalova; Luca Aquili; Raymond Chuen-Chung Chang et al.
Source: Self-asserted source
You-Qiang Song via Crossref Metadata Search

Deviation from baseline mutation burden provides powerful and robust rare-variants association test for complex diseases

Nucleic Acids Research
2022-04-08 | Journal article
DOI: 10.1093/nar/gkab1234
Contributors: Lin Jiang; Hui Jiang; Sheng Dai; Ying Chen; Youqiang Song; Clara Sze-Man Tang; Shirley Yin-Yu Pang; Shu-Leong Ho; Binbin Wang; Maria-Mercedes Garcia-Barcelo et al.
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Prevalence of mild behavioural impairment domains: a meta‐analysis

Psychogeriatrics
2022-01 | Journal article
DOI: 10.1111/psyg.12782
Contributors: Yining Pan; Yat‐Fung Shea; Zahinoor Ismail; Henry Ka‐Fung Mak; Patrick Ka‐Chun Chiu; Leung‐Wing Chu; You‐qiang Song
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Crossref

Autophagy in Alzheimer’s disease pathogenesis: Therapeutic potential and future perspectives

Ageing Research Reviews
2021-12 | Journal article
DOI: 10.1016/j.arr.2021.101464
Contributors: Zhigang Zhang; Xifei Yang; You-Qiang Song; Jie Tu
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Crossref

Amyloid-β toxicity modulates tau phosphorylation through the PAX6 signalling pathway.

Brain : a journal of neurology
2021-08-24 | Journal article
DOI: 10.1093/brain/awab134
PMID: 34428276
Source: Self-asserted source
You-Qiang Song

Identification of Copy Number Variants in a Southern Chinese Cohort of Patients with Congenital Scoliosis

Genes
2021-08-05 | Journal article
DOI: 10.3390/genes12081213
Contributors: Wenjing Lai; Xin Feng; Ming Yue; Prudence W. H. Cheung; Vanessa N. T. Choi; You-Qiang Song; Keith D. K. Luk; Jason Pui Yin Cheung; Bo Gao
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Sustained viremia suppression by SHIVSF162P3CN-recalled effector-memory CD8+ T cells after PD1-based vaccination

PLOS Pathogens
2021-06-14 | Journal article | Author
DOI: 10.1371/journal.ppat.1009647
Part of ISSN: 1553-7374
Contributors: Yik Chun Wong; Wan Liu; Lok Yan Yim; Xin Li; Hui Wang; Ming Yue; Mengyue Niu; Lin Cheng; Lijun Ling; Yanhua Du et al.
Source: Self-asserted source
You-Qiang Song via Crossref Metadata Search

Exploring the multifunctional role of melatonin in regulating autophagy and sleep to mitigate Alzheimer’s disease neuropathology

Ageing Research Reviews
2021-05 | Journal article
DOI: 10.1016/j.arr.2021.101304
Contributors: Md. Farhad Hossain; Ni Wang; Ruijun Chen; Siwen Li; Jaydeep Roy; Md. Giash Uddin; Zhong Li; Lee Wei Lim; You-Qiang Song
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Crossref

Established Beta Amyloid Pathology Is Unaffected by TREM2 Elevation in Reactive Microglia in an Alzheimer’s Disease Mouse Model

Molecules
2021-05-04 | Journal article
DOI: 10.3390/molecules26092685
Contributors: Qiuju Yuan; Xiaodong Liu; Yi Zhang; Yan-Fang Xian; Juntao Zou; Xie Zhang; Pengyun Huang; You-Qiang Song; Zhi-Xiu Lin
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Botanical Drug Puerarin Ameliorates Liposaccharide‐Induced Depressive Behaviors in Mice via Inhibiting RagA/mTOR/p70S6K Pathways

Oxidative Medicine and Cellular Longevity
2021-01 | Journal article
DOI: 10.1155/2021/7716201
Contributors: Jia Zhao; Yizhen Jia; Wei Zhao; Huixin Chen; Xiuying Zhang; Fung Yin Ngo; Dan Luo; Youqiang Song; Lixing Lao; Jianhui Rong et al.
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Crossref

Prevalence of mild behavioural impairment: a systematic review and meta‐analysis

Psychogeriatrics
2020-12 | Journal article
DOI: 10.1111/psyg.12636
Part of ISSN: 1479-8301
Contributors: Yining; Yat Fung Shea; Siwen Li; Ruijun Chen; Henry Ka‐Fung Mak; Patrick Ka‐Chun Chiu; Leung‐Wing Chu; You‐qiang Song
Source: Self-asserted source
You-Qiang Song via Crossref Metadata Search

Kindlin-2 regulates skeletal homeostasis by modulating PTH1R in mice

Signal Transduction and Targeted Therapy
2020-12-26 | Journal article
DOI: 10.1038/s41392-020-00328-y
Part of ISSN: 2059-3635
Contributors: Xuekun Fu; Bo Zhou; Qinnan Yan; Chu Tao; Lei Qin; Xiaohao Wu; Sixiong Lin; Sheng Chen; Yumei Lai; Xuenong Zou et al.
Source: Self-asserted source
You-Qiang Song via Crossref Metadata Search

Th2 cell regulatory and effector molecules single nucleotide polymorphisms and periodontitis

Journal of Leukocyte Biology
2020-11-01 | Journal article
DOI: 10.1002/JLB.4MA0720-698RR
Contributors: Ying Zheng; Lei Chai; Yanhui Fan; You-Qiang Song; Kwan-Yat Zee; Wen Wei Tu; Lijian Jin; Wai Keung Leung
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Pedigree analysis of lumbar developmental spinal stenosis: Determination of potential inheritance patterns.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society
2020-09-09 | Journal article
DOI: 10.1002/jor.24850
PMID: 32902878
Source: Self-asserted source
You-Qiang Song
grade
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Microfluidics-Based Systems in Diagnosis of Alzheimer's Disease and Biomimetic Modeling.

Micromachines
2020-08-19 | Journal article
DOI: 10.3390/mi11090787
PMID: 32825153
PMC: PMC7569794
Source: Self-asserted source
You-Qiang Song

Intracisternal injection of beta-amyloid seeds promotes cerebral amyloid angiopathy.

Brain, behavior, and immunity
2020-07-30 | Journal article
DOI: 10.1016/j.bbi.2020.07.038
PMID: 32739364
Source: Self-asserted source
You-Qiang Song
grade
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Associations between CLU polymorphisms and memory performance: The role of serum lipids in Alzheimer's disease.

Journal of psychiatric research
2020-07-29 | Journal article
DOI: 10.1016/j.jpsychires.2020.07.015
PMID: 32882505
Source: Self-asserted source
You-Qiang Song
grade
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Genetic variants of TBX6 and TBXT identified in patients with congenital scoliosis in Southern China.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society
2020-07-16 | Journal article
DOI: 10.1002/jor.24805
PMID: 32672867
Source: Self-asserted source
You-Qiang Song

A multiethnic meta-analysis defined the association of rs12946942 with severe adolescent idiopathic scoliosis

Journal of Human Genetics
2019 | Journal article
DOI: 10.1038/s10038-019-0575-7
EID:

2-s2.0-85061838312
Contributors: Takeda, K.; Kou, I.; Otomo, N.; Grauers, A.; Fan, Y.-H.; Ogura, Y.; Takahashi, Y.; Momozawa, Y.; Einarsdottir, E.; Kere, J. et al.
Source: Self-asserted source
You-Qiang Song via Scopus - Elsevier

Association Between Axonopathy and Amyloid Plaques in the Spinal Cord of the Transgenic Mice of Alzheimer's Disease

Neuroscience
2019 | Journal article
DOI: 10.1016/j.neuroscience.2019.04.037
EID:

2-s2.0-85065650448
Contributors: Yuan, Q.; Zhang, H.; Zhang, X.; Huang, P.; Liu, R.; Song, Y.-Q.; Wu, W.; Lin, Z.-X.
Source: Self-asserted source
You-Qiang Song via Scopus - Elsevier

Origins of Beta Amyloid Differ Between Vascular Amyloid Deposition and Parenchymal Amyloid Plaques in the Spinal Cord of a Mouse Model of Alzheimer's Disease.

Molecular neurobiology
2019-07-19 | Journal article
DOI: 10.1007/s12035-019-01697-4
PMID: 31325023
Source: Self-asserted source
You-Qiang Song
grade
Preferred source (of 2)‎

Heterodimeric DNA motif synthesis and validations.

Nucleic acids research
2019-02-01 | Journal article
DOI: 10.1093/nar/gky1297
PMID: 30590725
PMC: PMC6393289
Source: Self-asserted source
You-Qiang Song
grade
Preferred source (of 2)‎

A multi-ethnic meta-analysis confirms the association of rs6570507 with adolescent idiopathic scoliosis

Scientific Reports
2018 | Journal article
DOI: 10.1038/s41598-018-29011-7
EID:

2-s2.0-85050965417
Contributors: Kou, I.; Watanabe, K.; Takahashi, Y.; Momozawa, Y.; Khanshour, A.; Grauers, A.; Zhou, H.; Liu, G.; Fan, Y.-H.; Takeda, K. et al.
Source: Self-asserted source
You-Qiang Song via Scopus - Elsevier

A rare variant in MLKL confers susceptibility to ApoE ɛ4-negative Alzheimer's disease in Hong Kong Chinese population

Neurobiology of Aging
2018 | Journal article
DOI: 10.1016/j.neurobiolaging.2018.03.006
EID:

2-s2.0-85045204367
Contributors: Wang, B.; Bao, S.; Zhang, Z.; Zhou, X.; Wang, J.; Fan, Y.; Zhang, Y.; Li, Y.; Chen, L.; Jia, Y. et al.
Source: Self-asserted source
You-Qiang Song via Scopus - Elsevier
grade
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An international meta-analysis confirms the association of BNC2 with adolescent idiopathic scoliosis

Scientific Reports
2018 | Journal article
DOI: 10.1038/s41598-018-22552-x
EID:

2-s2.0-85044237943
Contributors: Ogura, Y.; Takeda, K.; Kou, I.; Khanshour, A.; Grauers, A.; Zhou, H.; Liu, G.; Fan, Y.-H.; Zhou, T.; Wu, Z. et al.
Source: Self-asserted source
You-Qiang Song via Scopus - Elsevier

Epigenetics and bone diseases

Genetics Research
2018 | Journal article
DOI: 10.1017/S0016672318000034
EID:

2-s2.0-85052662404
Contributors: Huang, T.; Peng, X.; Li, Z.; Zhou, Q.; Huang, S.; Wang, Y.; Li, J.; Song, Y.
Source: Self-asserted source
You-Qiang Song via Scopus - Elsevier

Genome-wide meta-analysis and replication studies in multiple ethnicities identify novel adolescent idiopathic scoliosis susceptibility loci

Human Molecular Genetics
2018 | Journal article
DOI: 10.1093/hmg/ddy306
EID:

2-s2.0-85056288930
Contributors: Khanshour, A.M.; Kou, I.; Fan, Y.; Einarsdottir, E.; Makki, N.; Kidane, Y.H.; Kere, J.; Grauers, A.; Johnson, T.A.; Paria, N. et al.
Source: Self-asserted source
You-Qiang Song via Scopus - Elsevier

Integrated analysis of mRNA-seq and miRNA-seq for host susceptibilities to influenza A (H7N9) infection in inbred mouse lines

Functional and Integrative Genomics
2018 | Journal article
DOI: 10.1007/s10142-018-0602-3
EID:

2-s2.0-85044248185
Contributors: Bao, S.; Jia, L.; Zhou, X.; Zhang, Z.-G.; Wu, H.W.L.; Yu, Z.; Ng, G.; Fan, Y.; Wong, D.S.M.; Huang, S. et al.
Source: Self-asserted source
You-Qiang Song via Scopus - Elsevier
grade
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Mutations in Hnrnpa1 cause congenital heart defects

JCI insight
2018 | Journal article
DOI: 10.1172/jci.insight.98555
EID:

2-s2.0-85062247804
Contributors: Yu, Z.; Tang, P.L.; Wang, J.; Bao, S.; Shieh, J.T.; Leung, A.W.; Zhang, Z.; Gao, F.; Wong, S.Y.; Hui, A.L. et al.
Source: Self-asserted source
You-Qiang Song via Scopus - Elsevier
grade
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Trans-ethnic polygenic analysis supports genetic overlaps of lumbar disc degeneration with height, body mass index, and bone mineral density

Frontiers in Genetics
2018 | Journal article
DOI: 10.3389/fgene.2018.00267
EID:

2-s2.0-85051841640
Contributors: Zhou, X.; Cheung, C.-L.; Karasugi, T.; Karppinen, J.; Samartzis, D.; Hsu, Y.-H.; Mak, T.S.-H.; Song, Y.-Q.; Chiba, K.; Kawaguchi, Y. et al.
Source: Self-asserted source
You-Qiang Song via Scopus - Elsevier

A new role of anterograde motor Kif5b in facilitating large clathrin-coated vesicle mediated endocytosis via regulating clathrin uncoating.

Cell discovery
2018-12-25 | Journal article
DOI: 10.1038/s41421-018-0067-5
PMID: 30603101
PMC: PMC6305376
Source: Self-asserted source
You-Qiang Song
grade
Preferred source (of 2)‎

The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

Human genetics
2018-07-17 | Journal article
DOI: 10.1007/s00439-018-1910-3
PMID: 30019117
PMC: PMC6200315
Source: Self-asserted source
You-Qiang Song
grade
Preferred source (of 2)‎

Genetic Polymorphisms in Estrogen Metabolic Pathway Associated with Risks of Alzheimer's Disease: Evidence from a Southern Chinese Population

Journal of the American Geriatrics Society
2017 | Journal article
DOI: 10.1111/jgs.14537
EID:

2-s2.0-85012867349
Contributors: Chen, L.H.; Fan, Y.H.; Kao, P.Y.P.; Ho, D.T.Y.; Ha, J.C.T.; Chu, L.W.; Song, Y.-Q.
Source: Self-asserted source
You-Qiang Song via Scopus - Elsevier

PyHLA: Tests for the association between HLA alleles and diseases

BMC Bioinformatics
2017 | Journal article
DOI: 10.1186/s12859-017-1496-0
EID:

2-s2.0-85011661226
Contributors: Fan, Y.; Song, Y.-Q.
Source: Self-asserted source
You-Qiang Song via Scopus - Elsevier

Rare coding variants in MAPK7 predispose to adolescent idiopathic scoliosis

Human Mutation
2017 | Journal article
DOI: 10.1002/humu.23296
EID:

2-s2.0-85026299151
Contributors: Gao, W.; Chen, C.; Zhou, T.; Yang, S.; Gao, B.; Zhou, H.; Lian, C.; Wu, Z.; Qiu, X.; Yang, X. et al.
Source: Self-asserted source
You-Qiang Song via Scopus - Elsevier

Robust and rapid algorithms facilitate large-scale whole genome sequencing downstream analysis in an integrative framework.

Nucleic acids research
2017-05-01 | Journal article
DOI: 10.1093/nar/gkx019
PMID: 28115622
PMC: PMC5435951
Source: Self-asserted source
You-Qiang Song

A systematic review of familial Alzheimer's disease: Differences in presentation of clinical features among three mutated genes and potential ethnic differences

Journal of the Formosan Medical Association
2016 | Journal article
DOI: 10.1016/j.jfma.2015.08.004
EID:

2-s2.0-84960211552
Contributors: Shea, Y.-F.; Chu, L.-W.; Chan, A.O.K.; Ha, J.; Li, Y.; Song, Y.-Q.
Source: Self-asserted source
You-Qiang Song via Scopus - Elsevier

A γA-crystallin mouse mutant Secc with small eye, cataract and closed eyelid

PLoS ONE
2016 | Journal article
DOI: 10.1371/journal.pone.0160691
EID:

2-s2.0-84983528572
Contributors: Cheng, M.H.; Tam, C.N.; Choy, K.W.; Tsang, W.H.; Tsang, S.L.; Pang, C.P.; Song, Y.Q.; Sham, M.H.
Source: Self-asserted source
You-Qiang Song via Scopus - Elsevier
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