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Works (35)

Brain White Matter Changes in Non-demented Individuals with Color Discrimination Deficits and Their Association with Cognitive Impairment: A NODDI Study

Neuroscience Bulletin
2025-03-07 | Journal article
DOI: 10.1007/s12264-025-01373-9
Contributors: Jiejun Zhang; Peilin Huang; Lin Lin; Yingzhe Cheng; Weipin Weng; Jiahao Zheng; Yixin Sun; Shaofan Jiang; Xiaodong Pan
Source: check_circle
Crossref

Novel application of cycloastragenol target microglia for the treatment of Alzheimer's disease: Evidence from single-cell analysis, network pharmacology and experimental assessment

Phytomedicine
2025-02 | Journal article
DOI: 10.1016/j.phymed.2025.156502
Contributors: Weipin Weng; Baoping Lin; Jiahao Zheng; Yixin Sun; Zijing Li; Xiaochun Chen; Yanping Wang; Xiaodong Pan
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Crossref

Pterosin B improves cognitive dysfunction by promoting microglia M1/M2 polarization through inhibiting Klf5/Parp14 pathway

Phytomedicine
2024-12 | Journal article
DOI: 10.1016/j.phymed.2024.156152
Contributors: Yan Zhang; Ji-Cong Chen; Jia-Hao Zheng; Ying-zhe Cheng; Wei-pin Weng; Rong-Ling Zhong; Sheng-Lu Sun; Yu-Sheng Shi; Xiao-Dong Pan
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Crossref

Cycloastragenol reduces microglial NLRP3 inflammasome activation in Parkinson's disease models by promoting autophagy and reducing Scrib-driven ROS

Phytomedicine
2024-11 | Journal article
DOI: 10.1016/j.phymed.2024.156210
Contributors: Linjuan Feng; Hsuan Lo; Jiahao Zheng; Weipin Weng; Yixin Sun; Xiaodong Pan
Source: check_circle
Crossref

Efficacy, safety, and response predictors of Astragalus in patients with mild to moderate Alzheimer's disease: A study protocol of an assessor-blind, statistician-blind open-label randomized controlled trial

Contemporary Clinical Trials Communications
2024-10 | Journal article
DOI: 10.1016/j.conctc.2024.101339
Contributors: Yingzhe Cheng; Lin Lin; Peilin Huang; Jiejun Zhang; Xiaodong Pan
Source: check_circle
Crossref

Periodontitis‐induced neuroinflammation impacts dendritic spine immaturity and cognitive impairment

Oral Diseases
2024-05 | Journal article
DOI: 10.1111/odi.14674
Contributors: Changfu Xie; Qiuyang Zhang; Xinyi Ye; Weiliang Wu; Xiaojuan Cheng; Xiaoan Ye; Jianyong Ruan; Xiaodong Pan
Source: check_circle
Crossref

Brain white matter changes and their associations with non‐motor dysfunction in orthostatic hypotension in α‐synucleinopathy: A NODDI study

CNS Neuroscience & Therapeutics
2024-04 | Journal article
DOI: 10.1111/cns.14712
Contributors: Lin Lin; Peilin Huang; Yingzhe Cheng; Shaofan Jiang; Jiejun Zhang; Man Li; Jiahao Zheng; Xiaodong Pan; Yanping Wang
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Crossref

Aberrant microstructural integrity of white matter in mild and severe orthostatic hypotension: A NODDI study

CNS Neuroscience & Therapeutics
2024-02 | Journal article
DOI: 10.1111/cns.14586
Contributors: Yingzhe Cheng; Lin Lin; Shaofan Jiang; Peilin Huang; Jiejun Zhang; Jiawei Xin; Haibin Xu; Yanping Wang; Xiaodong Pan
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Crossref

Identification of common core ion channel genes in epilepsy and Alzheimer’s disease

Irish Journal of Medical Science (1971 -)
2024-02 | Journal article
DOI: 10.1007/s11845-023-03447-x
Contributors: Ting Tang; Xiang Li; Erhan Yu; Man Li; Xiaodong Pan
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Crossref

Synchronous monitoring of brain‐heart electrophysiology using heart rate variability coupled with rapid quantitative electroencephalography in orthostatic hypotension patients with α‐synucleinopathies: Rapid prediction of orthostatic hypotension and preliminary exploration of brain stimulation therapy

CNS Neuroscience & Therapeutics
2024-02 | Journal article
DOI: 10.1111/cns.14571
Contributors: Lin Lin; Yingzhe Cheng; Peilin Huang; Jiejun Zhang; Jiahao Zheng; Xiaodong Pan
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Crossref

Efficacy analysis of three brain stimulation techniques for Alzheimer’s disease: a meta-analysis of repeated transcranial magnetic stimulation, transcranial direct current stimulation, and deep brain stimulation

Expert Review of Neurotherapeutics
2024-01-02 | Journal article
DOI: 10.1080/14737175.2023.2293225
Contributors: Peilin Huang; Lin Lin; Jiejun Zhang; Yingzhe Cheng; Xiaodong Pan
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Crossref

Dendrobine rescues cognitive dysfunction in diabetic encephalopathy by inhibiting ferroptosis via activating Nrf2/GPX4 axis

Phytomedicine
2023-10 | Journal article
DOI: 10.1016/j.phymed.2023.154993
Contributors: Yu-Sheng Shi; Ji-Cong Chen; Lin Lin; Ying-Zhe Cheng; Yang Zhao; Yan Zhang; Xiao-Dong Pan
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Crossref

Cover Image, Volume 71, Issue 9

Glia
2023-09 | Journal article
DOI: 10.1002/glia.24210
Contributors: Linjuan Feng; Hsuan Lo; Zhaoxiang Hong; Jiahao Zheng; Yuhong Yan; Zucheng Ye; Xiaochun Chen; Xiaodong Pan
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Crossref

Microglial LRRK2‐mediated NFATc1 attenuates α‐synuclein immunotoxicity in association with CX3CR1‐induced migration and the lysosome‐initiated degradation

Glia
2023-09 | Journal article
DOI: 10.1002/glia.24422
Contributors: Linjuan Feng; Hsuan Lo; Zhaoxiang Hong; Jiahao Zheng; Yuhong Yan; Zucheng Ye; Xiaochun Chen; Xiaodong Pan
Source: check_circle
Crossref

Loss of cannabinoid receptor 2 promotes α-Synuclein-induced microglial synaptic pruning in nucleus accumbens by modulating the pCREB-c-Fos signaling pathway and complement system

Experimental Neurology
2023-01 | Journal article
DOI: 10.1016/j.expneurol.2022.114230
Part of ISSN: 0014-4886
Contributors: Xiaodong Pan; Linjuan Feng; Hsuan Lo; Hanlin You; Wei Wu; Xiaojuan Cheng; Jiawei Xin; Zucheng Ye; Xiaochun Chen; Xiaodong Pan
Source: Self-asserted source
Xiaodong Pan

Prediction of Alzheimer’s Disease Using Patterns of Methylation Levels in Key Immunologic-Related Genes

Journal of Alzheimer's Disease
2022-11-08 | Journal article
DOI: 10.3233/JAD-220701
Contributors: Junhan Lin; Siyu Yang; Chao Wang; Erhan Yu; Zhibao Zhu; Jinying Shi; Xiang Li; Jiawei Xin; Xiaochun Chen; Xiaodong Pan
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Crossref

LRRK2 Deficiency Aggravates Sleep Deprivation-Induced Cognitive Loss by Perturbing Synaptic Pruning in Mice

Brain Sciences
2022-09-06 | Journal article
DOI: 10.3390/brainsci12091200
Contributors: Xiaojuan Cheng; Xilin Wu; Yuying Zhang; Weian Li; Linjuan Feng; Hanlin You; Siyu Yang; Dongping Yang; Xiaochun Chen; Xiaodong Pan
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Age-related LRRK2 G2019S Mutation Impacts Microglial Dopaminergic Fiber Refinement and Synaptic Pruning Involved in Abnormal Behaviors

Journal of Molecular Neuroscience
2022-03 | Journal article
DOI: 10.1007/s12031-021-01896-6
Contributors: Qiuyang Zhang; Xiaojuan Cheng; Wei Wu; Siyu Yang; Hanlin You; Zucheng Ye; Nan Liu; Xiaochun Chen; Xiaodong Pan
Source: check_circle
Crossref

Development and application of a Chinese Version of the Language Screening Test (CLAST) in post-stroke patients.

Medicine
2020-09-01 | Journal article
DOI: 10.1097/md.0000000000022165
PMID: 32925781
PMC: PMC7489636
Source: Self-asserted source
Xiaodong Pan
grade
Preferred source (of 2)‎

CX3CR1 modulates cognitive dysfunction induced by sleep deprivation

2020-03-15 | Other
DOI: 10.21203/rs.3.rs-17240/v1
Contributors: Jia-wei Xin; Xiao-juan Cheng; Chang-fu Xie; Qiu-yang Zhang; Yi-lang Ke; Xuan-yu Huang; Xiao-chun Chen; Xiao-dong Pan
Source: check_circle
Crossref

Restoration of L-OPA1 alleviates acute ischemic stroke injury in rats via inhibiting neuronal apoptosis and preserving mitochondrial function.

Redox biology
2020-03-13 | Journal article
DOI: 10.1016/j.redox.2020.101503
PMID: 32199783
PMC: PMC7327985
Source: Self-asserted source
Xiaodong Pan

Exenatide alleviates mitochondrial dysfunction and cognitive impairment in the 5×FAD mouse model of Alzheimer's disease.

Behavioural brain research
2019-05-10 | Journal article
DOI: 10.1016/j.bbr.2019.111932
PMID: 31082410
Source: Self-asserted source
Xiaodong Pan

Risk Factors for Aphasia in Cerebral Small Vessel Diseases.

Current neurovascular research
2019-01-01 | Journal article
DOI: 10.2174/1567202616666190227202638
PMID: 30827240
Source: Self-asserted source
Xiaodong Pan

Abnormal resting-state functional connectivity in posterior cingulate cortex of Parkinson's disease with mild cognitive impairment and dementia.

CNS neuroscience & therapeutics
2018-03-03 | Journal article
DOI: 10.1111/cns.12838
PMID: 29500931
PMC: PMC6490031
Source: Self-asserted source
Xiaodong Pan
grade
Preferred source (of 3)‎

Netrin-1 Promotes Synaptic Formation and Axonal Regeneration via JNK1/c-Jun Pathway after the Middle Cerebral Artery Occlusion.

Frontiers in cellular neuroscience
2018-02-13 | Journal article
DOI: 10.3389/fncel.2018.00013
PMID: 29487502
PMC: PMC5816818
Source: Self-asserted source
Xiaodong Pan

Netrin-1 Prevents Rat Primary Cortical Neurons from Apoptosis via the DCC/ERK Pathway.

Frontiers in cellular neuroscience
2017-12-13 | Journal article
DOI: 10.3389/fncel.2017.00387
PMID: 29321724
PMC: PMC5733550
Source: Self-asserted source
Xiaodong Pan

18F-Labeled Benzyldiamine Derivatives as Novel Flexible Probes for Positron Emission Tomography of Cerebral β-Amyloid Plaques

Journal of Medicinal Chemistry
2016-12-08 | Journal article
DOI: 10.1021/acs.jmedchem.6b01063
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Source: Self-asserted source
Xiaodong Pan

Endoplasmic Reticulum Stress Induces the Early Appearance of Pro-apoptotic and Anti-apoptotic Proteins in Neurons of Five Familial Alzheimer's Disease Mice.

Chinese medical journal
2016-12-01 | Journal article
DOI: 10.4103/0366-6999.194643
PMID: 27901000
PMC: PMC5146794
Source: Self-asserted source
Xiaodong Pan

Amyloid β Protein Aggravates Neuronal Senescence and Cognitive Deficits in 5XFAD Mouse Model of Alzheimer's Disease.

Chinese medical journal
2016-08-01 | Journal article
DOI: 10.4103/0366-6999.186646
PMID: 27453234
PMC: PMC4976573
Source: Self-asserted source
Xiaodong Pan

APOE4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice.

Molecular neurodegeneration
2015-03-05 | Journal article
DOI: 10.1186/s13024-015-0002-2
PMID: 25871877
PMC: PMC4391134
Source: Self-asserted source
Xiaodong Pan

Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells.

European journal of pharmacology
2011-12-07 | Journal article
DOI: 10.1016/j.ejphar.2011.11.039
PMID: 22166376
Source: Self-asserted source
Xiaodong Pan

Microglial phagocytosis induced by fibrillar β-amyloid is attenuated by oligomeric β-amyloid: implications for Alzheimer's disease.

Molecular neurodegeneration
2011-06-30 | Journal article
DOI: 10.1186/1750-1326-6-45
PMID: 21718498
PMC: PMC3149591
Source: Self-asserted source
Xiaodong Pan

Ginsenoside Rg1 attenuates amyloid-beta content, regulates PKA/CREB activity, and improves cognitive performance in SAMP8 mice.

Journal of Alzheimer's disease : JAD
2010-01-01 | Journal article
DOI: 10.3233/jad-2010-1296
PMID: 20157253
Source: Self-asserted source
Xiaodong Pan

Tripchlorolide protects neuronal cells from microglia-mediated beta-amyloid neurotoxicity through inhibiting NF-kappaB and JNK signaling.

Glia
2009-08-01 | Journal article
DOI: 10.1002/glia.20844
PMID: 19170180
Source: Self-asserted source
Xiaodong Pan

Neuroprotective role of tripchlorolide on inflammatory neurotoxicity induced by lipopolysaccharide-activated microglia.

Biochemical pharmacology
2008-07-02 | Journal article
DOI: 10.1016/j.bcp.2008.05.018
PMID: 18602088
Source: Self-asserted source
Xiaodong Pan

Peer review (9 reviews for 6 publications/grants)

Review activity for BMC neurology (1)
Review activity for Experimental neurology. (2)
Review activity for Journal of neuroimmunology. (2)
Review activity for Metabolism, clinical and experimental. (1)
Review activity for Molecular neurodegeneration (1)
Review activity for Translational psychiatry. (2)
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