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Works (11)

A signature of enhanced proliferation associated with response and survival to anti-PD-L1 therapy in early-stage non-small cell lung cancer

Cell Reports Medicine
2024-03 | Journal article
DOI: 10.1016/j.xcrm.2024.101438
Contributors: Nasser K. Altorki; Bhavneet Bhinder; Alain C. Borczuk; Olivier Elemento; Vivek Mittal; Timothy E. McGraw
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Regulation of PD-L1 Trafficking from Synthesis to Degradation

Cancer Immunology Research
2023-07-05 | Journal article
DOI: 10.1158/2326-6066.CIR-22-0953
Contributors: Eyoel Yemanaberhan Lemma; Anudari Letian; Nasser K. Altorki; Timothy E. McGraw
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Disinhibition of Rab10 gates AMPAR insertion and spine enlargement during long-term potentiation

2022-06-17 | Preprint
DOI: 10.21203/rs.3.rs-1691042/v1
Contributors: Jie Wang; Jun Nishiyama; Paula Parra-Bueno; Elwy Okaz; Goksu Oz; Xiaodan Liu; Irena Suponitsky-Kroyter; Timothy McGraw; Erzsebet Szatmari; Ryohei Yasuda
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Global evolution of the tumor microenvironment associated with progression from preinvasive invasive to invasive human lung adenocarcinoma

Cell Reports
2022-04 | Journal article
DOI: 10.1016/j.celrep.2022.110639
Contributors: Nasser K. Altorki; Alain C. Borczuk; Sebron Harrison; Lauren K. Groner; Bhavneet Bhinder; Vivek Mittal; Olivier Elemento; Timothy E. McGraw
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Defective insulin-stimulated GLUT4 translocation in brown adipocytes induces systemic glucose homeostasis dysregulation independent of thermogenesis in female mice

Molecular Metabolism
2021-11 | Journal article
DOI: 10.1016/j.molmet.2021.101305
Contributors: Belén Picatoste; Lucie Yammine; Rosemary A. Leahey; David Soares; Emma F. Johnson; Paul Cohen; Timothy E. McGraw
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Proximity proteome mapping reveals PD-L1-dependent pathways disrupted by anti-PD-L1 antibody specifically in EGFR-mutant lung cancer cells

2021-09-17 | Preprint
DOI: 10.1101/2021.09.17.460833
Contributors: Anudari Letian; Eyoel Yemanaberhan Lemma; Paola Cavaliere; Noah Dephoure; Nasser K. Altorki; Timothy E. McGraw
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Insulin action in adipocytes, adipose remodeling, and systemic effects

Cell Metabolism
2021-04 | Journal article
DOI: 10.1016/j.cmet.2021.03.019
Contributors: Anna Santoro; Timothy E. McGraw; Barbara B. Kahn
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Blunting of insulin-stimulated glucose uptake in brown adipose tissue induces systemic metabolic dysregulation in female mice

2020-12-10 | Preprint
DOI: 10.1101/2020.12.09.416685
Contributors: Belén Picatoste; Lucie Yammine; Rosemary Leahey; David Soares; Paul Cohen; Timothy E. McGraw
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Evolution of immune escape mechanisms in the progression from preinvasive to invasive human lung adenocarcinoma

2020-04-18 | Preprint
DOI: 10.1101/2020.04.17.046540
Contributors: Nasser K. Altorki; Alain C. Borczuk; Vivek Mittal; Olivier Elemento; Timothy E. McGraw
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Insulin promoted mobilization of GLUT4 from a perinuclear storage site requires RAB10

2020-04-14 | Preprint
DOI: 10.1101/2020.04.14.040683
Contributors: Alexandria Brumfield; Natasha Chaudhary; Dorothee Molle; Jennifer Wen; Johannes Graumann; Timothy E. McGraw
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Distinct Akt phosphorylation states are required for insulin regulated Glut4 and Glut1-mediated glucose uptake

eLife
2017-06-07 | Journal article
DOI: 10.7554/eLife.26896
Contributors: Muheeb Beg; Nazish Abdullah; Fathima Shazna Thowfeik; Nasser K Altorki; Timothy E McGraw
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Peer review (1 review for 1 publication/grant)

Review activity for Nature communications (1)
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