Personal information

nanobiotechnology, nanomaterials, analytical biochemistry, bispecific antibodies, protein engineering, hybrid nanomaterials, Antibody-polymer conjugates
Australia

Activities

Employment (3)

University of Queensland: Brisbane, QLD, AU

2012-05-12 to present | Research Fellow (Australian Institute for Bioengineering and Nanotechnology/ Centre for Advanced Imaging)
Employment
Source: Self-asserted source
Christopher Howard

University of Cambridge: Cambridge, Cambridgeshire, GB

2009-05-01 to 2011-12-31 | Postdoctoral Researcher (Biochemistry)
Employment
Source: Self-asserted source
Christopher Howard

CBio Ltd: Brisbane, QLD, AU

2006-10-01 to 2009-04-20 | Research Scientist
Employment
Source: Self-asserted source
Christopher Howard

Education and qualifications (1)

Queensland University of Technology: Brisbane, QLD, AU

2006-10-05 | PhD (Life Sciences)
Education
Source: Self-asserted source
Christopher Howard

Funding (6)

mil38-cd3-BsAb production and characterisation

2017 to present | Contract
Minomic Ltd (Sydney, AU)
Source: Self-asserted source
Christopher Howard

Next generation hybrid nanomaterials: bispecific antibody-targeted polymers

2017 to present | Grant
Australian Research Council (ACT, ACT, AU)
GRANT_NUMBER:

LP15010073

Source: Self-asserted source
Christopher Howard

EGFR Targeted nanoparticle feasibility study,

2016-10 to 2017-04 | Grant
Samyang Biopharmaceuticals (Seoul, KR)
Source: Self-asserted source
Christopher Howard

ARC Training Centre for Biopharmaceutical Innovation

2016-01-01 to 2020-12-31 | Grant
Australian Research Council (Canberra, AU)
GRANT_NUMBER:

IC160100027

Source: Self-asserted source
Christopher Howard via DimensionsWizard

Immuno-polymeric drugs for prostate cancer therapy

Source: Self-asserted source
Christopher Howard via DimensionsWizard

Targeted delivery of cytotoxic agents using novel minicells and engineered bispecific antibodies

2012 to 2015 | Grant
Australian Research Council (ACT, ACT, AU)
GRANT_NUMBER:

LP110200126

Source: Self-asserted source
Christopher Howard

Works (50 of 82)

Items per page:
Page 1 of 2

Development and application of multivalent nanobody-functionalized plasmonic probes in SERS sensing platforms

Biosensors and Bioelectronics
2025-06 | Journal article
Contributors: Jing Wang; Quan Zhou; Kym Lowry; Christopher B. Howard; Matt Trau
Source: check_circle
Crossref

Immune-modulating nanomedicines for enhanced drug delivery to non-small-cell lung cancer

Biomaterials
2025-06 | Journal article
Contributors: Feifei Liu; Christopher B. Howard; Pie Huda; Nicholas L. Fletcher; Craig A. Bell; Idriss Blakey; Michael Agrez; Kristofer J. Thurecht
Source: check_circle
Crossref

Multiplexing Label-Free Polymeric Nanocarriers via Antipolymer Antibodies

ACS Sensors
2025-02-28 | Journal article
Contributors: James Humphries; Jody Hobson-Peters; Saikat Ghosh; Christopher B. Howard; Pie Huda; Craig A. Bell; Nicholas L. Fletcher; Kristian Kempe; Kristofer J. Thurecht
Source: check_circle
Crossref

mRNA Display Pipeline for Protein Biosensor Construction

ACS Sensors
2024-06-28 | Journal article
Contributors: Zhenling Cui; Cagla Ergun Ayva; Yi Jin Liew; Zhong Guo; Roxane Mutschler; Birgit Dreier; Maria M Fiorito; Patricia Walden; Christopher B Howard; Fernanda Ely et al.
Source: check_circle
Crossref

Click‐on Antibody Fragments for Customisable Targeted Nanomedicines – Site‐specific Tetrazine and Azide Functionalisation through Non‐canonical Amino Acid incorporation

Chemistry–Methods
2024-02 | Journal article
Contributors: Pie Huda; James Humphries; Nicholas L. Fletcher; Christopher B. Howard; Kristofer J. Thurecht; Craig A. Bell
Source: check_circle
Crossref

A universal reagent for detection of emerging diseases using bioengineered multifunctional yeast nanofragments

Nature Nanotechnology
2023-10 | Journal article
Contributors: Junrong Li; Christopher B. Howard; Shuvashis Dey; Kym Lowry; David M. Whiley; Simon Puttick; Stephen Rose; Richard J. Lobb; Alain Wuethrich; Selvakumar Edwardraja et al.
Source: check_circle
Crossref

Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia

Science Translational Medicine
2023-05-17 | Journal article
Contributors: Ernest Moles; Christopher B. Howard; Pie Huda; Mawar Karsa; Hannah McCalmont; Kathleen Kimpton; Alastair Duly; Yongjuan Chen; Yizhou Huang; Melinda L. Tursky et al.
Source: check_circle
Crossref

A Multiplexed SERS Microassay for Accurate Detection of SARS-CoV-2 and Variants of Concern

ACS Sensors
2023-04-28 | Journal article
Contributors: Courtney Vedelago; Junrong Li; Kym Lowry; Christopher Howard; Alain Wuethrich; Matt Trau
Source: check_circle
Crossref

Recent advances in the production of recombinant factor IX: bioprocessing and cell engineering

Critical Reviews in Biotechnology
2023-04-03 | Journal article
Contributors: Aiden C. Beauglehole; Dinora Roche Recinos; Cassandra L. Pegg; Yih Yean Lee; Victor Turnbull; Susann Herrmann; Esteban Marcellin; Christopher B. Howard; Benjamin L. Schulz
Source: check_circle
Crossref

Pharmacokinetics and Biodistribution of 89Zr-Miltuximab and Its Antibody Fragments as Glypican-1 Targeting Immuno-PET Agents in Glioblastoma

Molecular Pharmaceutics
2023-03-06 | Journal article
Contributors: Saikat Ghosh; Nicholas L. Fletcher; Pie Huda; Zachary H. Houston; Christopher B. Howard; Maria E. Lund; Yanling Lu; Douglas H. Campbell; Bradley J. Walsh; Kristofer J. Thurecht
Source: check_circle
Crossref

Confined microemulsion sono-polymerization of poly(ethylene glycol) nanoparticles for targeted delivery

Chemical Communications
2022 | Journal article
Contributors: Zhiliang Gao; Xiaoyu Li; Kaijie Zhao; Huimin Geng; Peiyu Zhang; Yi Ju; Pie Huda; Christopher B. Howard; Kristofer J. Thurecht; Muthupandian Ashokkumar et al.
Source: check_circle
Crossref

Detection of Dengue Virus 2 with Single Infected Mosquito Resolution Using Yeast Affinity Bionanofragments and Plasmonic SERS Nanoboxes

Analytical Chemistry
2022-10-18 | Journal article
Contributors: Fahimeh Farokhinejad; Junrong Li; Leon E. Hugo; Christopher B. Howard; Alain Wuethrich; Matt Trau
Source: check_circle
Crossref

Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications

Critical Reviews in Biotechnology
2022-10-03 | Journal article
Contributors: Michael A. MacDonald; Matthias Nöbel; Dinora Roche Recinos; Verónica S. Martínez; Benjamin L. Schulz; Christopher B. Howard; Kym Baker; Evan Shave; Yih Yean Lee; Esteban Marcellin et al.
Source: check_circle
Crossref

Antibody-Based Formats to Target Glioblastoma: Overcoming Barriers to Protein Drug Delivery

Molecular Pharmaceutics
2022-05-02 | Journal article
Contributors: Saikat Ghosh; Pie Huda; Nicholas L. Fletcher; Christopher B. Howard; Bradley Walsh; Douglas Campbell; Mark B. Pinkham; Kristofer J. Thurecht
Source: check_circle
Crossref

Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption

Biomaterials
2022-04 | Journal article
Contributors: Phillip W. Janowicz; Zachary H. Houston; Jens Bunt; Nicholas L. Fletcher; Craig A. Bell; Gary Cowin; Christopher B. Howard; Dewan Taslima; Nicholas Westra van Holthe; Amber Prior et al.
Source: check_circle
Crossref

Generation of Nanoyeast Single-Chain Variable Fragments as High-Avidity Biomaterials for Dengue Virus Detection

ACS Biomaterials Science & Engineering
2021-12-13 | Journal article
Contributors: Fahimeh Farokhinejad; Rebecca E. Lane; Richard J. Lobb; Selvakumar Edwardraja; Alain Wuethrich; Christopher B. Howard; Matt Trau
Source: check_circle
Crossref

Amplification-Free SARS-CoV-2 Detection Using Nanoyeast-scFv and Ultrasensitive Plasmonic Nanobox-Integrated Nanomixing Microassay

Analytical Chemistry
2021-07-27 | Journal article
Contributors: Junrong Li; Alain Wuethrich; Selvakumar Edwardraja; Richard J. Lobb; Simon Puttick; Stephen Rose; Christopher B. Howard; Matt Trau
Source: check_circle
Crossref

Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery

Chemical Science
2020 | Journal article
Contributors: Gayathri R. Ediriweera; Joshua D. Simpson; Adrian V. Fuchs; Taracad K. Venkatachalam; Matthias Van De Walle; Christopher B. Howard; Stephen M. Mahler; James P. Blinco; Nicholas L. Fletcher; Zachary H. Houston et al.
Source: check_circle
Crossref

Controlling the Biological Fate of Micellar Nanoparticles: Balancing Stealth and Targeting

ACS Nano
2020-10-27 | Journal article
Contributors: Amal J. Sivaram; Andri Wardiana; Sheilajen Alcantara; Stefan E. Sonderegger; Nicholas L. Fletcher; Zachary H. Houston; Christopher B. Howard; Stephen M. Mahler; Cameron Alexander; Stephen J. Kent et al.
Source: check_circle
Crossref

Understanding the Uptake of Nanomedicines at Different Stages of Brain Cancer Using a Modular Nanocarrier Platform and Precision Bispecific Antibodies

ACS Central Science
2020-05-27 | Journal article
Contributors: Zachary H. Houston; Jens Bunt; Kok-Siong Chen; Simon Puttick; Christopher B. Howard; Nicholas L. Fletcher; Adrian V. Fuchs; Jiwei Cui; Yi Ju; Gary Cowin et al.
Source: check_circle
Crossref

S-Trap Eliminates Cell Culture Media Polymeric Surfactants for Effective Proteomic Analysis of Mammalian Cell Bioreactor Supernatants

Journal of Proteome Research
2020-05-01 | Journal article
Contributors: Lucia F. Zacchi; Dinora Roche Recinos; Ellen Otte; Campbell Aitken; Tony Hunt; Vanessa Sandford; Yih Yean Lee; Benjamin L. Schulz; Christopher B. Howard
Source: check_circle
Crossref

S-Trap eliminates cell culture media polymeric surfactants for effective proteomic analysis of mammalian cell bioreactor supernatants

2020-02-18 | Preprint
Contributors: Lucia F. Zacchi; Dinora Roche Recinos; Ellen Otte; Campbell Aitken; Tony Hunt; Vanessa Sandford; Yih Yean Lee; Benjamin L. Schulz; Christopher B. Howard
Source: check_circle
Crossref

A SERS microfluidic platform for targeting multiple soluble immune checkpoints

Biosensors and Bioelectronics
2019 | Journal article
EID:

2-s2.0-85056207943

Contributors: Reza, K.K.; Sina, A.A.I.; Wuethrich, A.; Grewal, Y.S.; Howard, C.B.; Korbie, D.; Trau, M.
Source: Self-asserted source
Christopher Howard via Scopus - Elsevier

Cellular Targeting of Bispecific Antibody-Functionalized Poly(ethylene glycol) Capsules: Do Shape and Size Matter?

ACS applied materials & interfaces
2019 | Journal article
EID:

2-s2.0-85071355777

Contributors: Song, D.; Cui, J.; Ju, Y.; Faria, M.; Sun, H.; Howard, C.B.; Thurecht, K.J.; Caruso, F.
Source: Self-asserted source
Christopher Howard via Scopus - Elsevier

Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy

Biomaterials
2019 | Journal article
EID:

2-s2.0-85067283396

Contributors: Tang, J.; Li, B.; Howard, C.B.; Mahler, S.M.; Thurecht, K.J.; Wu, Y.; Huang, L.; Xu, Z.P.
Source: Self-asserted source
Christopher Howard via Scopus - Elsevier

Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing

Lab on a Chip
2019 | Journal article
Contributors: Lyndon J. Raftery; Christopher B. Howard; Yadveer S. Grewal; Ramanathan Vaidyanathan; Martina L. Jones; Will Anderson; Darren Korbie; Tania Duarte; Minh Duc Cao; Son Hoang Nguyen et al.
Source: check_circle
Crossref

Single droplet detection of immune checkpoints on a multiplexed electrohydrodynamic biosensor

The Analyst
2019 | Journal article
Contributors: Alain Wuethrich; Aswin Raj Rajkumar; Karthik Balaji Shanmugasundaram; Kamil K. Reza; Shuvashis Dey; Christopher B. Howard; Abu Ali Ibn Sina; Matt Trau
Source: check_circle
Crossref

Wavelength-Dependent Fluorescent Immunosensors via Incorporation of Polarity Indicators near the Binding Interface of Antibody Fragments

Analytical Chemistry
2019 | Journal article
EID:

2-s2.0-85066980165

Contributors: Islam, J.; Riley, B.T.; Fercher, C.; Jones, M.L.; Buckle, A.M.; Howard, C.B.; Cox, R.P.; Bell, T.D.M.; Mahler, S.; Corrie, S.R.
Source: Self-asserted source
Christopher Howard via Scopus - Elsevier

Glycoproteomic measurement of site-specific polysialylation

2019-08-20 | Other
Contributors: Ruby Pelingon; Cassandra L. Pegg; Lucia F. Zacchi; Toan K. Phung; Christopher B. Howard; Ping Xu; Matthew P. Hardy; Catherine M. Owczarek; Benjamin L. Schulz
Source: check_circle
Crossref

Modulating Targeting of Poly(ethylene glycol) Particles to Tumor Cells Using Bispecific Antibodies

Advanced Healthcare Materials
2019-05 | Journal article
Contributors: Jiwei Cui; Yi Ju; Zachary H. Houston; Joshua J. Glass; Nicholas L. Fletcher; Sheilajen Alcantara; Qiong Dai; Christopher B. Howard; Stephen M. Mahler; Adam K. Wheatley et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Identification of novel glycosylation events on human serum-derived Factor IX

2019-03-05 | Other
Contributors: Cassandra L. Pegg; Lucia F. Zacchi; Dinora Roche Recinos; Christopher B. Howard; Benjamin L. Schulz
Source: check_circle
Crossref

Bispecific Antibody-Functionalized Upconversion Nanoprobe

Analytical Chemistry
2018 | Journal article
EID:

2-s2.0-85043451589

Contributors: He, H.; Howard, C.B.; Chen, Y.; Wen, S.; Lin, G.; Zhou, J.; Thurecht, K.J.; Jin, D.
Source: Self-asserted source
Christopher Howard via Scopus - Elsevier

Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands

Nanoscale
2018 | Journal article
Contributors: Jie Tang; Christopher B. Howard; Stephen M. Mahler; Kristofer J. Thurecht; Leaf Huang; Zhi Ping Xu
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach

mAbs
2018 | Journal article
EID:

2-s2.0-85045464158

Contributors: Fontaine, F.R.; Goodall, S.; Prokop, J.W.; Howard, C.B.; Moustaqil, M.; Kumble, S.; Rasicci, D.T.; Osborne, G.W.; Gambin, Y.; Sierecki, E. et al.
Source: Self-asserted source
Christopher Howard via Scopus - Elsevier

Geometric optimisation of electrohydrodynamic fluid flows for enhanced biosensing

Microchemical Journal
2018 | Journal article
EID:

2-s2.0-85033601941

Contributors: Wuethrich, A.; Howard, C.B.; Trau, M.
Source: Self-asserted source
Christopher Howard via Scopus - Elsevier

Multiplexed SERS Detection of Soluble Cancer Protein Biomarkers with Gold-Silver Alloy Nanoboxes and Nanoyeast Single-Chain Variable Fragments

Analytical Chemistry
2018 | Journal article
EID:

2-s2.0-85052406086

Contributors: Li, J.; Wang, J.; Grewal, Y.S.; Howard, C.B.; Raftery, L.J.; Mahler, S.; Wang, Y.; Trau, M.
Source: Self-asserted source
Christopher Howard via Scopus - Elsevier

RNA interference to enhance radiation therapy: Targeting the DNA damage response

Cancer Letters
2018-12 | Journal article
Contributors: G. Ratnayake; A.L. Bain; N. Fletcher; C.B. Howard; K.K. Khanna; K.J. Thurecht
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Enhanced uptake of potassium or glycine betaine or export of cyclic-di-AMP restores osmoresistance in a high cyclic-di-AMP Lactococcus lactis mutant

PLOS Genetics
2018-08-03 | Journal article
Contributors: Huong Thi Pham; Danielle A. Garsin; Nguyen Thi Hanh Nhiep; Thu Ngoc Minh Vu; TuAnh Ngoc Huynh; Yan Zhu; Anh Le Diep Huynh; Alolika Chakrabortti; Esteban Marcellin; Raquel Lo et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Recent Advances in the Generation of Antibody-Nanomaterial Conjugates.

Advanced healthcare materials
2018-01 | Journal article
Contributors: Sivaram AJ; Wardiana A; Howard CB; Mahler SM; Thurecht KJ
Source: Self-asserted source
Christopher Howard via Europe PubMed Central
grade
Preferred source (of 2)‎

Insights into the interfacial structure-function of poly(ethylene glycol)-decorated peptide-stabilised nanoscale emulsions.

Soft matter
2017-11 | Journal article
Contributors: Tayeb HH; Piantavigna S; Howard CB; Nouwens A; Mahler SM; Middelberg APJ; He L; Holt SA; Sainsbury F
Source: Self-asserted source
Christopher Howard via Europe PubMed Central
grade
Preferred source (of 2)‎

Targeting mesothelin receptors with drug-loaded bacterial nanocells suppresses human mesothelioma tumour growth in mouse xenograft models

PLOS ONE
2017-10-23 | Journal article
Contributors: Mohamed A. Alfaleh; Arun Rishi; Christopher B. Howard; Ilya Sedliarou; Martina L. Jones; Reema Gudhka; Natasha Vanegas; Jocelyn Weiss; Julia H. Suurbach; Christopher J. de Bakker et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Beyond Antibodies: Development of a Novel Protein Scaffold Based on Human Chaperonin 10

Scientific Reports
2016 | Journal article
EID:

2-s2.0-84996538957

Contributors: Alsultan, A.M.; Chin, D.Y.; Howard, C.B.; De Bakker, C.J.; Jones, M.L.; Mahler, S.M.
Source: Self-asserted source
Christopher Howard via Scopus - Elsevier

Biosensing made easy with PEG-targeted bi-specific antibodies

Chemical Communications
2016 | Journal article
EID:

2-s2.0-84966447624

Contributors: Raftery, L.J.; Grewal, Y.S.; Howard, C.B.; Jones, M.L.; Shiddiky, M.J.A.; Carrascosa, L.G.; Thurecht, K.J.; Mahler, S.M.; Trau, M.
Source: Self-asserted source
Christopher Howard via Scopus - Elsevier

Biosimilars approved for treatment of inflammatory rheumatological diseases

International Journal of Rheumatic Diseases
2016 | Journal article
EID:

2-s2.0-85007347322

Contributors: Mahler, S.M.; Wardiana, A.; Jones, M.L.; de Bakker, C.J.; Graham, G.G.; Howard, C.B.
Source: Self-asserted source
Christopher Howard via Scopus - Elsevier

Invited Speaker. International conference. Targeted delivery of nanomedicines using Bispecific Antibodies. PEGS China, Shanghai.

2016 | Lecture
Source: Self-asserted source
Christopher Howard

Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies

Advanced Healthcare Materials
2016 | Journal article
EID:

2-s2.0-84983490987

Contributors: Howard, C.B.; Fletcher, N.; Houston, Z.H.; Fuchs, A.V.; Boase, N.R.B.; Simpson, J.D.; Raftery, L.J.; Ruder, T.; Jones, M.L.; de Bakker, C.J. et al.
Source: Self-asserted source
Christopher Howard via Scopus - Elsevier

Targeted Nanomaterials: Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies (Adv. Healthcare Mater. 16/2016)

Advanced Healthcare Materials
2016 | Journal article
EID:

2-s2.0-84983548262

Contributors: Howard, C.B.; Fletcher, N.; Houston, Z.H.; Fuchs, A.V.; Boase, N.R.B.; Simpson, J.D.; Raftery, L.J.; Ruder, T.; Jones, M.L.; de Bakker, C.J. et al.
Source: Self-asserted source
Christopher Howard via Scopus - Elsevier

Targeting membrane proteins for antibody discovery using phage display

Scientific Reports
2016 | Journal article
EID:

2-s2.0-84969920073

Contributors: Jones, M.L.; Alfaleh, M.A.; Kumble, S.; Zhang, S.; Osborne, G.W.; Yeh, M.; Arora, N.; Hou, J.J.C.; Howard, C.B.; Chin, D.Y. et al.
Source: Self-asserted source
Christopher Howard via Scopus - Elsevier

Invited Speaker. Targeted delivery of nanomedicines using Bispecific Antibodies.Centre of Excellence in Convergent Bio-Nano Science Workshop, Barossa Valley, Adelaide

2016-12 | Lecture
Source: Self-asserted source
Christopher Howard

Invited Speaker. Targeted delivery of nanomedicines using Bispecific Antibodies.7th International Nanomedicine Conference, Coogee Sydney.

2016-06 | Lecture
Source: Self-asserted source
Christopher Howard
Items per page:
Page 1 of 2

Peer review (4 reviews for 3 publications/grants)

Review activity for ACS nano. (1)
Review activity for ACS synthetic biology. (1)
Review activity for Molecular pharmaceutics. (2)