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Employment (2)

Mercer University School of Medicine: Macon, GA, US

2016-11-01 to present | Assistant Professor (Biomedical Sciences)
Employment
Source: Self-asserted source
Mohammed Abdelsaid

Augusta University: Augusta , GA, US

2012-02-04 to 2016-10-30 | Post-Doc (Physiology)
Employment
Source: Self-asserted source
Mohammed Abdelsaid

Education and qualifications (3)

University of Georgia: Athens, GA, US

2007-08-16 to 2011-12-16 | PhD (Clinical and Administrative Therapeutics )
Education
Source: Self-asserted source
Mohammed Abdelsaid

Al-Azhar University: Cairo, EG

2002-10-15 to 2006 | Masters in Medicinal chemistry (Pharmacy)
Education
Source: Self-asserted source
Mohammed Abdelsaid

Ain Shams University: Cairo, EG

1996-09-20 to 2001-05-20 | B. Pharm (School of Pharmacy)
Education
Source: Self-asserted source
Mohammed Abdelsaid

Funding (5)

The Role of RAAS system in COVID-19 induced Cognitive impairments

2023-04-01 to 2025-03-31 | Grant
American Heart Association (Dallas, US)
DOI: 10.58275/AHA.23AIREA1045073.pc.gr.167523
GRANT_NUMBER:

23AIREA1045073
Source: check_circle
American Heart Association

Cellular and molecular mechanisms for SARS‑CoV‑2-induced cognitive dysfunction.

2021-07 to 2022-06 | Award
Mercer University (GA, GA, US)
Source: Self-asserted source
Mohammed Abdelsaid

Role of pericyte in diabetes induced pathological neovascularization

2016-07 to 2019-06 | Grant
American Heart Association (TX, TX, US)
GRANT_NUMBER:

16 SDG30270013
Source: Self-asserted source
Mohammed Abdelsaid

Role of Robo4 in diabetes induced pathological neovascularization

2014-07 to 2016-07 | Award
American Heart Association (TX, TX, US)
GRANT_NUMBER:

14POST19580004
Source: Self-asserted source
Mohammed Abdelsaid

Role of TXNIP in diabetic retinopathy

2010-06 to 2011-12 | Award
American Heart Association (TX, TX, US)
GRANT_NUMBER:

10PRE3660004
Source: Self-asserted source
Mohammed Abdelsaid

Works (29)

SARS-CoV-2 Spike Protein Exacerbates Thromboembolic Cerebrovascular Complications in Humanized ACE2 Mouse Model

Translational Stroke Research
2024-10-02 | Journal article
DOI: 10.1007/s12975-024-01301-5
Contributors: Stan P. Heath; Veronica C. Hermanns; Maha Coucha; Mohammed Abdelsaid
Source: check_circle
Crossref

SARS-CoV-2 Spike Protein Intensifies Cerebrovascular Complications in Diabetic hACE2 Mice through RAAS and TLR Signaling Activation

International Journal of Molecular Sciences
2023-11-16 | Journal article
DOI: 10.3390/ijms242216394
Contributors: Faith N. Burnett; Maha Coucha; Deanna R. Bolduc; Veronica C. Hermanns; Stan P. Heath; Maryam Abdelghani; Lilia Z. Macias-Moriarity; Mohammed Abdelsaid
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

GLP-1 receptor nitration contributes to loss of brain pericyte function in a mouse model of diabetes

Diabetologia
2022-09 | Journal article
DOI: 10.1007/s00125-022-05730-5
Contributors: Joseph Bailey; Maha Coucha; Deanna R. Bolduc; Faith N. Burnett; Amy C. Barrett; Mark Ghaly; Mohammed Abdelsaid
Source: check_circle
Crossref

Deferoxamine Treatment Prevents Post-Stroke Vasoregression and Neurovascular Unit Remodeling Leading to Improved Functional Outcomes in Type 2 Male Diabetic Rats: Role of Endothelial Ferroptosis.

Translational stroke research
2020-09-01 | Journal article
DOI: 10.1007/s12975-020-00844-7
PMID: 32875455
Source: Self-asserted source
Mohammed Abdelsaid

Inhibition of Ephrin-B2 in brain pericytes decreases cerebral pathological neovascularization in diabetic rats

PLOS ONE
2019-01-08 | Journal article
DOI: 10.1371/journal.pone.0210523
Contributors: Maha Coucha; Alexander V. Ljubimov; Amy C. Barrett; Mostafa Elgebaly; Adviye Ergul; Mohammed Abdelsaid
Source: check_circle
Crossref

Inhibition of Toll-Like Receptor-4 (TLR-4) Improves Neurobehavioral Outcomes After Acute Ischemic Stroke in Diabetic Rats: Possible Role of Vascular Endothelial TLR-4.

Molecular neurobiology
2018-06-16 | Journal article
DOI: 10.1007/s12035-018-1184-8
PMID: 29909454
Source: Self-asserted source
Mohammed Abdelsaid

Impact of Metabolic Diseases on Cerebral Circulation: Structural and Functional Consequences.

Comprehensive Physiology
2018-03-25 | Journal article
DOI: 10.1002/cphy.c170019
PMID: 29687902
PMC: PMC6586018
Source: Self-asserted source
Mohammed Abdelsaid

Peroxynitrite-Induced Tyrosine Nitration Contributes to Matrix Metalloprotease-3 Activation: Relevance to Hyperglycemic Ischemic Brain Injury and Tissue Plasminogen Activator.

Neurochemical research
2017-10-03 | Journal article
DOI: 10.1007/s11064-017-2411-9
PMID: 28975464
PMC: PMC5801117
Source: Self-asserted source
Mohammed Abdelsaid

Enhanced VEGF signalling mediates cerebral neovascularisation via downregulation of guidance protein ROBO4 in a rat model of diabetes.

Diabetologia
2017-01-23 | Journal article
DOI: 10.1007/s00125-017-4214-6
PMID: 28116460
PMC: PMC5342922
Source: Self-asserted source
Mohammed Abdelsaid

Nox4 contributes to the hypoxia-mediated regulation of actin cytoskeleton in cerebrovascular smooth muscle.

Life sciences
2016-08-21 | Journal article
DOI: 10.1016/j.lfs.2016.08.018
PMID: 27558234
PMC: PMC5028312
Source: Self-asserted source
Mohammed Abdelsaid

Linagliptin treatment improves cerebrovascular function and remodeling and restores reduced cerebral perfusion in Type 2 diabetes.

American journal of physiology. Regulatory, integrative and comparative physiology
2016-06-29 | Journal article
DOI: 10.1152/ajpregu.00057.2016
PMID: 27357799
PMC: PMC5142225
Source: Self-asserted source
Mohammed Abdelsaid

Matrix Metalloprotease 3 Exacerbates Hemorrhagic Transformation and Worsens Functional Outcomes in Hyperglycemic Stroke.

Stroke
2016-02-02 | Journal article
DOI: 10.1161/STROKEAHA.115.011258
PMID: 26839355
PMC: PMC4766051
Source: Self-asserted source
Mohammed Abdelsaid
grade
Preferred source (of 2)‎

Linagliptin attenuates diabetes-induced cerebral pathological neovascularization in a blood glucose-independent manner: Potential role of ET-1.

Life sciences
2015-11-26 | Journal article
DOI: 10.1016/j.lfs.2015.11.026
PMID: 26631506
PMC: PMC4882278
Source: Self-asserted source
Mohammed Abdelsaid

The Chemokine Platelet Factor-4 Variant (PF-4var)/CXCL4L1 Inhibits Diabetes-Induced Blood-Retinal Barrier Breakdown.

Investigative ophthalmology & visual science
2015-02-24 | Journal article
DOI: 10.1167/iovs.14-16144
PMID: 25711636
PMC: PMC4365984
Source: Self-asserted source
Mohammed Abdelsaid

A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase.

Journal of lipid research
2015-01-17 | Journal article
DOI: 10.1194/jlr.M056069
PMID: 25598081
PMC: PMC4340307
Source: Self-asserted source
Mohammed Abdelsaid

SOD1 overexpression prevents acute hyperglycemia-induced cerebral myogenic dysfunction: relevance to contralateral hemisphere and stroke outcomes.

American journal of physiology. Heart and circulatory physiology
2014-12-31 | Journal article
DOI: 10.1152/ajpheart.00321.2014
PMID: 25552308
PMC: PMC4346767
Source: Self-asserted source
Mohammed Abdelsaid

Metformin treatment in the period after stroke prevents nitrative stress and restores angiogenic signaling in the brain in diabetes.

Diabetes
2014-12-18 | Journal article
DOI: 10.2337/db14-1423
PMID: 25524911
PMC: PMC4407857
Source: Self-asserted source
Mohammed Abdelsaid
grade
Preferred source (of 3)‎

Deletion of thioredoxin interacting protein (TXNIP) augments hyperoxia-induced vaso-obliteration in a mouse model of oxygen induced-retinopathy.

PloS one
2014-10-16 | Journal article
DOI: 10.1371/journal.pone.0110388
PMID: 25329456
PMC: PMC4199686
Source: Self-asserted source
Mohammed Abdelsaid

Cerebrovasculoprotective effects of azilsartan medoxomil in diabetes.

Translational research : the journal of laboratory and clinical medicine
2014-06-17 | Journal article
DOI: 10.1016/j.trsl.2014.06.003
PMID: 24999268
PMC: PMC4250409
Source: Self-asserted source
Mohammed Abdelsaid
grade
Preferred source (of 2)‎

Cerebral neovascularization in diabetes: implications for stroke recovery and beyond.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
2014-02-05 | Journal article
DOI: 10.1038/jcbfm.2014.18
PMID: 24496174
PMC: PMC3982092
Source: Self-asserted source
Mohammed Abdelsaid
grade
Preferred source (of 2)‎

Dual endothelin receptor antagonism with bosentan reverses established vascular remodeling and dysfunctional angiogenesis in diabetic rats: relevance to glycemic control.

Life sciences
2014-01-18 | Journal article
DOI: 10.1016/j.lfs.2014.01.008
PMID: 24447630
PMC: PMC4103965
Source: Self-asserted source
Mohammed Abdelsaid

Late dual endothelin receptor blockade with bosentan restores impaired cerebrovascular function in diabetes.

Life sciences
2014-01-13 | Journal article
DOI: 10.1016/j.lfs.2013.12.231
PMID: 24434796
PMC: PMC4096617
Source: Self-asserted source
Mohammed Abdelsaid

Pronerve growth factor induces angiogenesis via activation of TrkA: possible role in proliferative diabetic retinopathy.

Journal of diabetes research
2013-08-12 | Journal article
DOI: 10.1155/2013/432659
PMID: 23998130
PMC: PMC3753742
Source: Self-asserted source
Mohammed Abdelsaid

Thioredoxin-interacting protein expression is required for VEGF-mediated angiogenic signal in endothelial cells.

Antioxidants & redox signaling
2013-07-12 | Journal article
DOI: 10.1089/ars.2012.4761
PMID: 23718729
PMC: PMC3869450
Source: Self-asserted source
Mohammed Abdelsaid
grade
Preferred source (of 2)‎

S-glutathionylation of LMW-PTP regulates VEGF-mediated FAK activation and endothelial cell migration.

Journal of cell science
2012-08-01 | Journal article
DOI: 10.1242/jcs.103481
PMID: 22854047
Source: Self-asserted source
Mohammed Abdelsaid

Alteration of growth factors and neuronal death in diabetic retinopathy: what we have learned so far.

Molecular vision
2011-01-28 | Journal article
PMID: 21293735
PMC: PMC3032276
Source: Self-asserted source
Mohammed Abdelsaid

Diabetes-induced peroxynitrite impairs the balance of pro-nerve growth factor and nerve growth factor, and causes neurovascular injury.

Diabetologia
2010-10-19 | Journal article
DOI: 10.1007/s00125-010-1935-1
PMID: 20957344
Source: Self-asserted source
Mohammed Abdelsaid

Early intervention of tyrosine nitration prevents vaso-obliteration and neovascularization in ischemic retinopathy.

The Journal of pharmacology and experimental therapeutics
2009-10-08 | Journal article
DOI: 10.1124/jpet.109.157941
PMID: 19815813
Source: Self-asserted source
Mohammed Abdelsaid

Candesartan augments ischemia-induced proangiogenic state and results in sustained improvement after stroke.

Stroke
2009-03-05 | Journal article
DOI: 10.1161/STROKEAHA.108.537225
PMID: 19265050
PMC: PMC2716175
Source: Self-asserted source
Mohammed Abdelsaid

Peer review (3 reviews for 3 publications/grants)

Review activity for Age. (1)
Review activity for Biochimica et biophysica acta. (1)
Review activity for Journal of clinical neuroscience. (1)
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