Personal information

Microbiology, Metabolomics, Natural products, Plant-fungal interactions, Myrtle rust, Cyanobacteria
Australia

Activities

Employment (3)

University of Western Sydney: Penrith, NSW, AU

2006-10 to present | Senior Lecturer in Microbiology (School of Science)
Employment
Source: Self-asserted source
Michelle Moffitt

Scripps Institution of Oceanography: La Jolla, California, US

2005 to 2006 | Postdoctoral researcher
Employment
Source: Self-asserted source
Michelle Moffitt

University of Arizona: Tucson, US

2003 to 2005 | Postdoctoral researcher
Employment
Source: Self-asserted source
Michelle Moffitt

Education and qualifications (2)

University of New South Wales: Sydney, NSW, AU

1999 to 2003 | PhD
Qualification
Source: Self-asserted source
Michelle Moffitt

University of New South Wales: Sydney, NSW, AU

1995 to 1998 | Bachelor Science, Honours 1st class
Education
Source: Self-asserted source
Michelle Moffitt

Professional activities (2)

Australian Society for Microbiology: Melbourne, Victoria, AU

2021 to present
Membership
Source: Self-asserted source
Michelle Moffitt

Australian Plant Biosecurity Science Foundation: Canberra, AU

2019 to present | Foundation member
Membership
Source: Self-asserted source
Michelle Moffitt

Funding (5)

Australian Advanced Metabolic Signal Discovery, and Imaging Platform

2024-01-01 to 2024-12-31 | Grant
Australian Research Council (Canberra, AU)
GRANT_NUMBER: LE240100068
Source: Self-asserted source
Michelle Moffitt via DimensionsWizard

Exploring how Australia’s unique microbial diversity can naturally protect endangered native trees from Myrtle rust.

2023-07 to 2026-06 | Grant
Hermon Slade Foundation (Port Macquarie, AU)
Source: Self-asserted source
Michelle Moffitt

Using metabolites as biomarkers for the identification of innate resistance to myrtle rust

2021-01 to 2021-12 | Grant
Australian Plant Biosecurity Science Foundation (Canberra, AU)
GRANT_NUMBER: PBSF037
Source: Self-asserted source
Michelle Moffitt

Developing molecular 'fingerprinting' of myrtle rust disease to facilitate strategies in monitoring and control

2020-01 to 2021-02 | Grant
Australian Plant Biosecurity Science Foundation (Canberra, AU)
GRANT_NUMBER: PBSF023
Source: Self-asserted source
Michelle Moffitt

Polyketides as the conserved basis for diverse marine toxin biosyntheses

2008-01-01 to 2010-12-31 | Grant
Australian Research Council (Canberra, AU)
GRANT_NUMBER: DP0880264
Source: Self-asserted source
Michelle Moffitt via DimensionsWizard

Works (37)

Both Constitutive and Infection-Responsive Secondary Metabolites Linked to Resistance against Austropuccinia psidii (Myrtle Rust) in Melaleuca quinquenervia

Microorganisms
2022-02-07 | Journal article
Contributors: Michelle C. Moffitt; Johanna Wong-Bajracharya; Louise S. Shuey; Robert F. Park; Geoff S. Pegg; Jonathan M. Plett
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Identification of promoter elements in the Dolichospermum circinale AWQC131C saxitoxin gene cluster and the experimental analysis of their use for heterologous expression

BMC Microbiology
2020-12 | Journal article
Contributors: Paul M. D’Agostino; Bakir Al-Sinawi; Rabia Mazmouz; Julia Muenchhoff; Brett A. Neilan; Michelle C. Moffitt
Source: check_circle
Crossref
grade
Preferred source (of 5)‎

Draft Genome Sequence of the Fungus Lecanicillium psalliotae Strain HWLR35, Isolated from a Wheat Leaf Infected with Leaf Rust (Caused by Puccinia triticina )

Genome Announcements
2018-01-11 | Journal article
Contributors: Gregory F. S. Harm; Alexie Papanicolaou; William S. Cuddy; Robert F. Park; Michelle C. Moffitt
Source: check_circle
Crossref

Advances in genomics, transcriptomics and proteomics of toxin-producing cyanobacteria

Environmental Microbiology Reports
2016 | Journal article
EID:

2-s2.0-84958845047

Contributors: D'Agostino, P.M.; Woodhouse, J.N.; Makower, A.K.; Yeung, A.C.Y.; Ongley, S.E.; Micallef, M.L.; Moffitt, M.C.; Neilan, B.A.
Source: Self-asserted source
Michelle Moffitt via Scopus - Elsevier

Proteogenomics of a saxitoxin-producing and non-toxic strain of Anabaena circinalis (cyanobacteria) in response to extracellular NaCl and phosphate depletion

Environmental Microbiology
2016 | Journal article
EID:

2-s2.0-84959301018

Contributors: D'Agostino, P.M.; Song, X.; Neilan, B.A.; Moffitt, M.C.
Source: Self-asserted source
Michelle Moffitt via Scopus - Elsevier

Genome mining for natural product biosynthetic gene clusters in the Subsection V cyanobacteria

BMC Genomics
2015 | Journal article
EID:

2-s2.0-84940531115

Contributors: Micallef, M.L.; D'Agostino, P.M.; Sharma, D.; Viswanathan, R.; Moffitt, M.C.
Source: Self-asserted source
Michelle Moffitt via Scopus - Elsevier

Exploring cyanobacterial genomes for natural product biosynthesis pathways

Marine Genomics
2015-06 | Journal article
Contributors: Melinda L. Micallef; Paul M. D'Agostino; Bakir Al-Sinawi; Brett A. Neilan; Michelle C. Moffitt
Source: check_circle
Crossref

An in vitro study of the photodynamic effect of rose bengal on trichophyton rubrum

Journal of Biophotonics
2014 | Journal article
EID:

2-s2.0-84901657687

Contributors: Cronin, L.; Moffitt, M.; Mawad, D.; Morton, O.C.; Lauto, A.; Stack, C.
Source: Self-asserted source
Michelle Moffitt via Scopus - Elsevier

An investigation into the inhibitory effect of ultraviolet radiation on Trichophyton rubrum

Lasers in Medical Science
2014 | Journal article
DOI:

10.1007/s10103-013-1287-4

Part of ISSN:

0268-8921;1435-604X

Contributors: Cronin, Leah J.; Mildren, Richard P.; Moffitt, Michelle; Lauto, Antonio; Morton, C. Oliver; Stack, Colin M.
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Comparative analysis of hapalindole, ambiguine and welwitindolinone gene clusters and reconstitution of indole-isonitrile biosynthesis from cyanobacteria

BMC Microbiology
2014 | Journal article
EID:

2-s2.0-84906558589

Contributors: Micallef, M.L.; Sharma, D.; Bunn, B.M.; Gerwick, L.; Viswanathan, R.; Moffitt, M.C.
Source: Self-asserted source
Michelle Moffitt via Scopus - Elsevier

Comparative proteomics reveals that a saxitoxin-producing and a nontoxic strain of Anabaena circinalis are two different ecotypes

Journal of Proteome Research
2014 | Journal article
EID:

2-s2.0-84896770392

Contributors: D'Agostino, P.M.; Song, X.; Neilan, B.A.; Moffitt, M.C.
Source: Self-asserted source
Michelle Moffitt via Scopus - Elsevier

Environmental conditions that influence toxin biosynthesis in cyanobacteria

Environmental Microbiology
2013 | Journal article
DOI:

10.1111/j.1462-2920.2012.02729.x

Part of ISSN:

1462-2912

Contributors: Neilan, Brett A.; Pearson, Leanne A.; Muenchhoff, Julia; Moffitt, Michelle C.; Dittmann, Elke
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Nodularin, a cyanobacterial toxin, is synthesized in planta by symbiotic Nostoc sp.

Isme Journal
2012 | Journal article
DOI:

10.1038/ismej.2012.25

Part of ISSN:

1751-7362

Contributors: Gehringer, Michelle M.; Adler, Lewis; Roberts, Alexandra A.; Moffitt, Michelle C.; Mihali, Troco K.; Mills, Toby J. T.; Fieker, Claus; Neilan, Brett A.
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Neurotoxic Alkaloids: Saxitoxin and Its Analogs

Marine Drugs
2010 | Journal article
DOI:

10.3390/md8072185

Part of ISSN:

1660-3397

Contributors: Wiese, Maria; D'Agostino, Paul M.; Mihali, Troco K.; Moffitt, Michelle C.; Neilan, Brett A.
Source: Self-asserted source
Michelle Moffitt via ResearcherID

On the Chemistry, Toxicology and Genetics of the Cyanobacterial Toxins, Microcystin, Nodularin, Saxitoxin and Cylindrospermopsin

Marine Drugs
2010 | Journal article
DOI:

10.3390/md8051650

Part of ISSN:

1660-3397

Contributors: Pearson, Leanne; Mihali, Troco; Moffitt, Michelle; Kellmann, Ralf; Neilan, Brett
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Hapalindole family of cyanobacterial natural products: Structure, biosynthesis, and function

Handbook on Cyanobacteria: Biochemistry, Biotechnology and Applications
2009 | Book
EID:

2-s2.0-84896147020

Contributors: Moffitt, M.C.; Burns, B.P.
Source: Self-asserted source
Michelle Moffitt via Scopus - Elsevier

HAPALINDOLE FAMILY OF CYANOBACTERIAL NATURAL PRODUCTS: STRUCTURE, BIOSYNTHESIS, AND FUNCTION

Handbook on Cyanobacteria: Biochemistry, Biotechnology and Applications
2009 | Journal article
Part of ISSN:

978-1-60741-092-8

Contributors: Moffitt, M. C.; Burns, B. P.; Gault, PM; Marler, HJ
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Chapter 17: The genetics and genomics of cyanobacterial toxicity

Cyanobacterial Harmful Algal Blooms: State of the Science and Research Needs
2008 | Book chapter
Part of ISBN:

0065-2598;978-0-387-75864-0

Contributors: Neilan, Brett A.; Pearson, L. A.; Moffitt, M. C.; Mihali, K. T.; Kaebemick, M.; Kellmann, R.; Pomati, F.; Hudnell, HK
Source: Self-asserted source
Michelle Moffitt via ResearcherID

The genetics and genomics of cyanobacterial toxicity.

Advances in experimental medicine and biology
2008 | Journal article
EID:

2-s2.0-45549087006

Contributors: Neilan, B.A.; Pearson, L.A.; Moffitt, M.C.; Mihali, K.T.; Kaebernick, M.; Kellmann, R.; Pomati, F.
Source: Self-asserted source
Michelle Moffitt via Scopus - Elsevier

The Molecular Genetics and Regulation of Cyanobacterial Peptide Hepatotoxin Biosynthesis

Critical Reviews in Toxicology
2008 | Journal article
DOI:

10.1080/10408440802291513

Part of ISSN:

1040-8444

Contributors: Pearson, L. A.; Moffitt, M. C.; Ginn, H. P.; Neilan, B. A.
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Discovery of two cyanobacterial phenylalanine ammonia lyases: Kinetic and structural characterization

Biochemistry
2007 | Journal article
DOI:

10.1021/bi061774g

Part of ISSN:

0006-2960

Contributors: Moffitt, Michelle C.; Louie, Gordon V.; Bowman, Marianne E.; Pence, Janelle; Noel, Joseph P.; Moore, Bradley S.
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Molecular basis for chloronium-mediated meroterpene cyclization - Cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster

Journal of Biological Chemistry
2007 | Journal article
DOI:

10.1074/jbc.M611046200

Part of ISSN:

0021-9258

Contributors: Winter, Jaclyn M.; Moffitt, Michelle C.; Zazopoulos, Emmanuel; McAlpine, James B.; Dorrestein, Pieter C.; Moore, Bradley S.
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Structural characterization of in vitro and in vivo intermediates on the loading module of microcystin synthetase

Acs Chemical Biology
2006 | Journal article
DOI:

10.1021/cb500007v

Part of ISSN:

1554-8929

Contributors: Hicks, Leslie M.; Moffitt, Michelle C.; Beer, Laura L.; Moore, Bradley S.; Kelleher, Neil L.
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases

Chemistry & Biology
2006 | Journal article
DOI:

10.1016/j.chembiol.2006.11.011

Part of ISSN:

1074-5521

Contributors: Louie, Gordon V.; Bowman, Marianne E.; Moffitt, Michelle C.; Baiga, Thomas J.; Moore, Bradley S.; Noel, Joseph P.
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Cereulide, the emetic toxin of Bacillus cereus, is putatively a product of nonribosomal peptide synthesis

Journal of Applied Microbiology
2004 | Journal article
DOI:

10.1111/j.1365-2672.2004.02381.x

Part of ISSN:

1364-5072

Contributors: Toh, M; Moffitt, MC; Henrichsen, L; Raftery, M; Barrow, K; Cox, JM; Marquis, CP; Neilan, BA
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Characterization of the nodularin synthetase gene cluster and proposed theory of the evolution of cyanobacterial hepatotoxins

Applied and Environmental Microbiology
2004 | Journal article
DOI:

10.1128/AEM.70.11.6353-6362.2004

Part of ISSN:

0099-2240

Contributors: Moffitt, MC; Neilan, BA
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Evidence for differences in the metabolism of saxitoxin and C1+2 toxins in the freshwater cyanobacterium Cylindrospermopsis raciborskii T3

Biochimica Et Biophysica Acta-General Subjects
2004 | Journal article
DOI:

10.1016/j.bbagen.2004.05.006

Part of ISSN:

0304-4165

Contributors: Pomati, F; Moffitt, MC; Cavaliere, R; Neilan, BA
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Molecular detection of genes responsible for cyanobacterial toxin production in the genera Microcystis, Nodularia, and Cylindrospermopsis

Public Health Microbiology: Methods and Protocols
2004 | Journal article
Part of ISSN:

1064-3745

Contributors: Burns, BP; Saker, ML; Moffitt, MC; Neilan, BA; Spencer, JFT; DeSpencer, ALR
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Molecular detection of genes responsible for cyanobacterial toxin production in the genera Microcystis, Nodularia, and Cylindrospermopsis.

Methods in molecular biology (Clifton, N.J.)
2004 | Journal article
EID:

2-s2.0-4043145055

Contributors: Burns, B.P.; Saker, M.L.; Moffitt, M.C.; Neilan, B.A.
Source: Self-asserted source
Michelle Moffitt via Scopus - Elsevier

Evolutionary affiliations within the superfamily of ketosynthases reflect complex pathway associations

Journal of Molecular Evolution
2003 | Journal article
DOI:

10.1007/s00239-002-2415-0

Part of ISSN:

0022-2844

Contributors: Moffitt, MC; Neilan, BA
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Absence of detectable levels of the cyanobacterial toxin (microcystin-LR) caffy-over into milk

Toxicon
2002 | Journal article
DOI:

10.1016/S0041-0101(02)00123-X

Part of ISSN:

0041-0101

Contributors: Feitz, AJ; Lukondeh, T; Moffitt, MC; Burns, BP; Naidoo, D; Vedova, JD; Gooden, JM; Neilan, BA
Source: Self-asserted source
Michelle Moffitt via ResearcherID

On the presence of peptide synthetase and polyketide synthase genes in the cyanobacterial genus Nodularia

Fems Microbiology Letters
2001 | Journal article
DOI:

10.1111/j.1574-6968.2001.tb10566.x

Part of ISSN:

0378-1097

Contributors: Moffitt, MC; Neilan, BA
Source: Self-asserted source
Michelle Moffitt via ResearcherID

On the presence of peptide synthetase and polyketide synthase genes in the cyanobacterial genus Nodularia

FEMS Microbiology Letters
2001 | Journal article
EID:

2-s2.0-0035868628

Contributors: Moffitt, M.C.; Neilan, B.A.
Source: Self-asserted source
Michelle Moffitt via Scopus - Elsevier

rRNA sequences reflect the ecophysiology and define the toxic cyanobacteria of the genus Nodularia

International Journal of Systematic and Evolutionary Microbiology
2001 | Journal article
Part of ISSN:

1466-5026

Contributors: Moffitt, MC; Blackburn, SI; Neilan, BA
Source: Self-asserted source
Michelle Moffitt via ResearcherID

rRNA sequences reflect the ecophysiology and define the toxic cyanobacteria of the genus Nodularia

International Journal of Systematic and Evolutionary Microbiology
2001 | Journal article
EID:

2-s2.0-0035065909

Contributors: Moffitt, M.C.; Blackburn, S.I.; Neilan, B.A.
Source: Self-asserted source
Michelle Moffitt via Scopus - Elsevier

The expansion of mechanistic and organismic diversity associated with non-ribosomal peptides

FEMS Microbiology Letters
2000 | Journal article
EID:

2-s2.0-0034668288

Contributors: Moffitt, M.C.; Neilan, B.A.
Source: Self-asserted source
Michelle Moffitt via Scopus - Elsevier

The expansion of mechanistic and organismic diversity associated with non-ribosomal peptides

Fems Microbiology Letters
2000 | Journal article
DOI:

10.1111/j.1574-6968.2000.tb09334.x

Part of ISSN:

0378-1097

Contributors: Moffitt, MC; Neilan, BA
Source: Self-asserted source
Michelle Moffitt via ResearcherID

Peer review (2 reviews for 2 publications/grants)

Review activity for Fungal genetics and biology. (1)
Review activity for Phytopathology research. (1)