Personal information

Emails & domains

Verified email domains

Other IDs

Scopus Author ID: 36189289400
Loop profile: 1400098

Biography

Peer-Reviewed Research Manuscripts
1. Carpenter SM, Lu LL. (2022). Leveraging Antibody, B Cell and Fc Receptor Interactions to Understand Heterogeneous Immune Responses in Tuberculosis. Front Immunol. 2022 Mar 17;13:830482. doi: 10.3389/fimmu.2022.830482. PMID: 35371092.
2. Sutiwisesak R., Hicks N.D., Boyce S., Murphy, K.C., Papavinasasundaram K., Carpenter, S.M., Boucau J., Joshi N., Le Gall S., Fortune, S.M., Sassetti, C.M., Behar, S.M. (2020). A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response. PLoS Pathog 16(10): e1009000. https://doi.org/10.1371/journal.ppat.1009000 PMID: 33075106
3. Yang J.D., Mott D., Sutiwisesak R., Lu Y-J., Raso F., Stowell B., Babunovic, G.H., Lee, J., Carpenter S.M., Way, S.S., Fortune, S.M., Behar, S.M. (2018) Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages. PLoS Pathog 14(5): e1007060. https://doi.org/10.1371/journal.ppat.1007060
4. Carpenter, S.M., & Behar, S. M. (2018). A new vaccine for tuberculosis in rhesus macaques. Nature Medicine, 24(2), 124–126. http://doi.org/10.1038/nm.4488
5. Carpenter S.M., Yang J.D., Lee J., Barreira-Silva P., Behar S.M. (2017) Vaccine-elicited memory CD4+ T cell expansion is impaired in the lungs during tuberculosis. PLoS Pathog 13(11): e1006704. https://doi.org/10.1371/journal. ppat.1006704
6. Booty MG, Barreira-Silva P, Carpenter S.M., Nunes-Alves C., Jacques M.K., Stowell B.L., Jayaraman P., Beamer G., Behar S.M. (2016). IL-21 signaling is essential for optimal host resistance against Mycobacterium tuberculosis infection. Scientific Reports, 11(6):36720. PMID: 27819295.
7. Booty, M. G., Nunes-Alves, C., Carpenter S.M., Jayaraman P., & Behar S. M. (2016). Multiple Inflammatory Cytokines Converge To Regulate CD8+ T Cell Expansion and Function during Tuberculosis. The Journal of Immunology, 196(4), 1822–1831. PMID: 26755819
8. Carpenter, S.M., Nunes-Alves, C., Booty, M. G., Way, S. S., & Behar, S. M. (2016). A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis. PLoS Pathog 12(1), e1005380. PMID: 26745507
9. Nishimura, T., Fujita-Suzuki, Y., Mori, M., Carpenter, S. M., Fujiwara, H., Uwamino, Y., Tamizo E., Tano I., Kawabe H., Hasegawa N. (2016). Middle-aged to elderly women have a higher asymptomatic infection rate with Mycobacterium avium complex, regardless of body habitus. Respirology (Carlton, Vic.), 21(3):553-5. PMID: 26639819
10. Nunes-Alves, C., Booty, M. G., Carpenter, S. M., Rothchild, A. C., Martin, C. J., Desjardins, D., Steblenko K, Kløverpris HN, Madansein R, Ramsuran D, Leslie A, Correia-Neves M, Behar SM (2015). Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection. PLoS Pathog 11(5), e1004849. PMID: 25945999
11. Behar, S. M., Carpenter, S. M., Booty, M. G., Barber, D. L., & Jayaraman, P. (2014). Orchestration of pulmonary T cell immunity during Mycobacterium tuberculosis infection: immunity interruptus. Seminars in Immunology, 26(6), 559–577. PMID: 25311810
12. Nunes-Alves, C., Booty, M. G., Carpenter, S. M., Jayaraman, P., Rothchild, A. C., & Behar, S. M. (2014). In search of a new paradigm for protective immunity to TB. Nature Reviews Microbiology, 12(4), 289–299. PMID: 24590243
13. Mishra, J., Carpenter, S., & Singh, S. (2010). Low serum zinc levels in an endemic area of visceral leishmaniasis in Bihar, India. The Indian Journal of Medical Research, 131, 793–798. PMID: 20571168
14. Otmakhov, N., Tao-Cheng, J.-H., Carpenter, S., Asrican, B., Dosemeci, A., Reese, T. S., & Lisman, J. (2004). Persistent accumulation of calcium/calmodulin-dependent protein kinase II in dendritic spines after induction of NMDA receptor-dependent chemical long-term potentiation. The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 24(42), 9324–9331 PMID: 15496668.
15. Otmakhov, N., Khibnik, L., Otmakhova, N., Carpenter, S., Riahi, S., Asrican, B., & Lisman, J. (2004). Forskolin-induced LTP in the CA1 hippocampa

Activities

Collapse all

Employment (9)

UH Cleveland Medical Center: Cleveland, OH, US

2020-09-01 to present | Assistant Professor (Medicine / Infectious Diseases and HIV Medicine)
Employment
Source: Self-asserted source
Stephen Carpenter

Case Western Reserve University School of Medicine: Cleveland, OH, US

2020-09-01 to present | Assistant Professor (Medicine / Infectious Diseases)
Employment
Source: Self-asserted source
Stephen Carpenter

Regeneron Pharmaceuticals Inc: Tarrytown, NY, US

2017-10-30 to 2020-08-07 | Director (Early Clinical Development and Experimental Sciences)
Employment
Source: Self-asserted source
Stephen Carpenter

Brigham and Women's Hospital: Boston, MA, US

2013-08-01 to 2017-12-15 | Associate Physician (Infectious Disease Division)
Employment
Source: Self-asserted source
Stephen Carpenter

University of Massachusetts Medical School: Worcester, MA, US

2013-08-01 to 2017-10-15 | Instructor (Microbiology and Physiological Systems (MaPS))
Employment
Source: Self-asserted source
Stephen Carpenter

Brigham and Women's Hospital: Boston, MA, US

2011-07-01 to 2013-07-31 | Research Fellow (Infectious Disease Division)
Employment
Source: Self-asserted source
Stephen Carpenter

Massachusetts General Hospital: Boston, MA, US

2010-07-01 to 2013-07-31 | Clinical and Research Fellow (Infectious Disease Division)
Employment
Source: Self-asserted source
Stephen Carpenter

New York University School of Medicine: New York, NY, US

2007-07-01 to 2010-06-30 | Resident Physician (Medicine)
Employment
Source: Self-asserted source
Stephen Carpenter

Brandeis University: Waltham, MA, US

2002-06-01 to 2003-08-15 | Research Assistant (Neuroscience)
Employment
Source: Self-asserted source
Stephen Carpenter

Education and qualifications (3)

University of Massachusetts Medical School: Worcester, MA, US

2013-09-01 to 2016-08-31 | Ph.D. (Biomedical Sciences (immunology, microbiology))
Education
Source: Self-asserted source
Stephen Carpenter

University of Massachusetts Medical School: Worcester, MA, US

2003-08-30 to 2007-06-02 | M.D. (Medicine)
Education
Source: Self-asserted source
Stephen Carpenter

Brandeis University: Waltham, MA, US

1998-08-27 to 2002-05-28 | B.S. (Neuroscience, Biology)
Education
Source: Self-asserted source
Stephen Carpenter

Professional activities (5)

Infectious Diseases Society of America: Arlington, VA, US

2021-11 to present | Elected Member (Research Committee)
Invited position
Source: Self-asserted source
Stephen Carpenter

AIDS Clinical Trials Group (ACTG): Boston, MA, US

2021-02 to present | Appointed Immunologist (Tuberculosis Transformative Science Group (TB-TSG))
Invited position
Source: Self-asserted source
Stephen Carpenter

American Society of Hematology: Washington, DC, US

2018-04 to present | Member
Membership
Source: Self-asserted source
Stephen Carpenter

Infectious Diseases Society of America: Arlington, VA, US

2010-07 to present | Member
Membership
Source: Self-asserted source
Stephen Carpenter

Westchester Business Council: White Plains, NY, US

2019-06-30 | "40 under 40" Rising Star
Distinction
Source: Self-asserted source
Stephen Carpenter

Funding (7)

Protective attributes of Mycobacterium tuberculosis-specific human lung resident memory T cells

2022-07-01 to 2024-06-30 | Grant
American Lung Association (Chicago, US)
GRANT_NUMBER:

924107
Source: check_circle
ProposalCentral

Research in Immunity to Tuberculosis

2020-09 to 2025-08 | Award
University Hospitals Cleveland Medical Center (Cleveland, US)
GRANT_NUMBER:

Research Startup
Source: Self-asserted source
Stephen Carpenter

Investigating immunological outliers to understand protective adaptive immunity against tuberculosis

2017-09 to 2018-08 | Award
Broad Institute (Cambridge, MA, US)
GRANT_NUMBER:

TB Gift Innovation
Source: Self-asserted source
Stephen Carpenter

Human CD4+ T Cell Function In Tuberculosis

2016-10 to 2018-09 | Grant
NIH/NIAID (Bethesda, MD, US)
GRANT_NUMBER:

L30 AI 113797-03

Source: Self-asserted source
Stephen Carpenter

Clonality of TB10.4-specific T cell responses in tuberculosis patients

2014-10 to 2016-09 | Grant
NIH / NIAID (Bethesda, MD, US)
GRANT_NUMBER:

L30 AI 113797-02
Source: Self-asserted source
Stephen Carpenter

Memory CD8+ T cell function in tuberculosis

2013-09 to 2016-08 | Salary award
University of Massachusetts Medical School (Worcester, MA, MA, US)
Source: Self-asserted source
Stephen Carpenter

Antigen-Specific CD8+ T Cells In Tuberculosis

2011-08 to 2013-07 | Grant
NIH / NIAID (Bethesda, MD, US)
GRANT_NUMBER:

T32 AI 007061
Source: Self-asserted source
Stephen Carpenter

Works (22)

Human memory CD4+T-cells recognizeMycobacterium tuberculosis-infected macrophages amid broader pathogen-specific responses

2025-02-27 | Preprint
DOI: 10.1101/2025.02.23.639515
Contributors: Volodymyr Stetsenko; Daniel P. Gail; Scott Reba; Vinicius G. Suzart; Avinaash K. Sandhu; Alessandro Sette; Mohammad Haj Dezfulian; Cecilia S. Lindestam Arlehamn; Stephen M. Carpenter
Source: check_circle
Crossref

Reply to Barajas-Ochoa: The Imperative to Integrate International Medical Graduates into the Infectious Diseases Physician-Scientist Pathway: Expanding Opportunities and Overcoming Barriers

The Journal of Infectious Diseases
2024-09-23 | Journal article
DOI: 10.1093/infdis/jiae272
Contributors: Talia H Swartz; Senu Apewokin; Stephen M Carpenter; Rana Chakraborty; Ann M Dennis; Eric Houpt; Neeraj K Surana; Danielle M Zerr; Liise-anne Pirofski
Source: check_circle
Crossref

Analyzing human CD4+ T cells activated in response to macrophages infected with Mycobacterium tuberculosis

STAR Protocols
2024-03 | Journal article
DOI: 10.1016/j.xpro.2024.102939
Contributors: Daniel P. Gail; Vinicius G. Suzart; Stephen M. Carpenter
Source: check_circle
Crossref

A Call to Action: Urgently Strengthening the Future Physician-Scientist Workforce in Infectious Diseases

The Journal of Infectious Diseases
2024-03-14 | Journal article
DOI: 10.1093/infdis/jiad610
Contributors: Talia H Swartz; Senu Apewokin; Stephen M Carpenter; Rana Chakraborty; Ann M Dennis; Eric Houpt; Neeraj K Surana; Danielle M Zerr; Liise-anne Pirofski
Source: check_circle
Crossref

Impact of Mycobacterium tuberculosis Glycolipids on the CD4+ T Cell–Macrophage Immunological Synapse

The Journal of Immunology
2023-11-01 | Journal article
DOI: 10.4049/jimmunol.2300107
Contributors: Ivan Mwebaza; Rachel Shaw; Qing Li; Shane Fletcher; Jacqueline M Achkar; Clifford V Harding; Stephen M Carpenter; W Henry Boom
Source: check_circle
Crossref

Leveraging Antibody, B Cell and Fc Receptor Interactions to Understand Heterogeneous Immune Responses in Tuberculosis.

Frontiers in immunology
2022-03-17 | Journal article
DOI: 10.3389/fimmu.2022.830482
PMID: 35371092
PMC: PMC8968866
Source: Self-asserted source
Stephen Carpenter

A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response

PLOS Pathogens
2020-10-19 | Journal article
DOI: 10.1371/journal.ppat.1009000
Contributors: Rujapak Sutiwisesak; David M. Lewinsohn; Nathan D. Hicks; Shayla Boyce; Kenan C. Murphy; Kadamba Papavinasasundaram; Stephen M. Carpenter; Julie Boucau; Neelambari Joshi; Sylvie Le Gall et al.
Source: check_circle
Crossref

Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages

PLOS Pathogens
2018-05-21 | Journal article
DOI: 10.1371/journal.ppat.1007060
Contributors: Jason D. Yang; David M. Lewinsohn; Daniel Mott; Rujapak Sutiwisesak; Yu-Jung Lu; Fiona Raso; Britni Stowell; Greg Hunter Babunovic; Jinhee Lee; Steve M. Carpenter et al.
Source: check_circle
Crossref

A new vaccine for tuberculosis in rhesus macaques

Nature Medicine
2018-02 | Journal article
DOI: 10.1038/nm.4488
Part of ISSN: 1078-8956
Part of ISSN: 1546-170X
Source: Self-asserted source
Stephen Carpenter

Vaccine-elicited memory CD4+ T cell expansion is impaired in the lungs during tuberculosis

PLOS Pathogens
2017-11-27 | Journal article
DOI: 10.1371/journal.ppat.1006704
Contributors: Stephen M. Carpenter; Padmini Salgame; Jason D. Yang; Jinhee Lee; Palmira Barreira-Silva; Samuel M. Behar
Source: check_circle
Crossref

A Higher Activation Threshold of Memory CD8<sup>+</sup> T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis

PLoS Pathogens
2016 | Journal article
DOI: 10.1371/journal.ppat.1005380
EID:

2-s2.0-84956740578
Contributors: Carpenter, S.M.; Nunes-Alves, C.; Booty, M.G.; Way, S.S.; Behar, S.M.
Source: Self-asserted source
Stephen Carpenter via Scopus - Elsevier

IL-21 signaling is essential for optimal host resistance against Mycobacterium tuberculosis infection

Scientific Reports
2016 | Journal article
DOI: 10.1038/srep36720
EID:

2-s2.0-84994852261
Contributors: Booty, M.G.; Barreira-Silva, P.; Carpenter, S.M.; Nunes-Alves, C.; Jacques, M.K.; Stowell, B.L.; Jayaraman, P.; Beamer, G.; Behar, S.M.
Source: Self-asserted source
Stephen Carpenter via Scopus - Elsevier

Middle-aged to elderly women have a higher asymptomatic infection rate with Mycobacterium avium complex, regardless of body habitus

Respirology
2016 | Journal article
DOI: 10.1111/resp.12699
EID:

2-s2.0-84961658258
Contributors: Nishimura, T.; Fujita-Suzuki, Y.; Mori, M.; Carpenter, S.M.; Fujiwara, H.; Uwamino, Y.; Tamizu, E.; Yano, I.; Kawabe, H.; Hasegawa, N.
Source: Self-asserted source
Stephen Carpenter via Scopus - Elsevier

Multiple inflammatory cytokines converge to regulate CD8<sup>+</sup> T cell expansion and function during tuberculosis

Journal of Immunology
2016 | Journal article
DOI: 10.4049/jimmunol.1502206
EID:

2-s2.0-84958582444
Contributors: Booty, M.G.; Nunes-Alves, C.; Carpenter, S.M.; Jayaraman, P.; Behar, S.M.
Source: Self-asserted source
Stephen Carpenter via Scopus - Elsevier

Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection

PLoS Pathogens
2015 | Journal article
DOI: 10.1371/journal.ppat.1004849
EID:

2-s2.0-84930341569
Contributors: Nunes-Alves, C.; Booty, M.G.; Carpenter, S.M.; Rothchild, A.C.; Martin, C.J.; Desjardins, D.; Steblenko, K.; Kløverpris, H.N.; Madansein, R.; Ramsuran, D. et al.
Source: Self-asserted source
Stephen Carpenter via Scopus - Elsevier

Recurrence of disseminated Mycobacterium avium complex disease in a patient with anti-gamma interferon autoantibodies by reinfection

Journal of Clinical Microbiology
2015 | Journal article
DOI: 10.1128/JCM.03339-14
EID:

2-s2.0-84925263195
Contributors: Nishimura, T.; Fujita-Suzuki, Y.; Yonemaru, M.; Ohkusu, K.; Sakagami, T.; Carpenter, S.M.; Otsuka, Y.; Namkoong, H.; Yano, I.; Hasegawa, N.
Source: Self-asserted source
Stephen Carpenter via Scopus - Elsevier

In search of a new paradigm for protective immunity to TB

Nature Reviews Microbiology
2014 | Journal article
DOI: 10.1038/nrmicro3230
EID:

2-s2.0-84896388520
Contributors: Nunes-Alves, C.; Booty, M.G.; Carpenter, S.M.; Jayaraman, P.; Rothchild, A.C.; Behar, S.M.
Source: Self-asserted source
Stephen Carpenter via Scopus - Elsevier

Orchestration of pulmonary t cell immunity during mycobacterium tuberculosis infection: Immunity interruptus

Seminars in Immunology
2014 | Journal article
DOI: 10.1016/j.smim.2014.09.003
EID:

2-s2.0-84920057801
Contributors: Behar, S.M.; Carpenter, S.M.; Booty, M.G.; Barber, D.L.; Jayaraman, P.
Source: Self-asserted source
Stephen Carpenter via Scopus - Elsevier

Case records of the Massachusetts General Hospital. Case 20-2011. A 30-year-old man with diarrhea after a trip to the Dominican Republic.

The New England journal of medicine
2011-06-01 | Journal article
DOI: 10.1056/nejmcpc1100928
PMID: 21714651
Source: Self-asserted source
Stephen Carpenter

Low serum zinc levels in an endemic area of visceral leishmaniasis in Bihar, India

Indian Journal of Medical Research
2010 | Journal article
EID:

2-s2.0-77953337570
Contributors: Mishra, J.; Carpenter, S.; Singh, S.
Source: Self-asserted source
Stephen Carpenter via Scopus - Elsevier

Forskolin-Induced LTP in the CA1 Hippocampal Region Is NMDA Receptor Dependent

Journal of Neurophysiology
2004 | Journal article
DOI: 10.1152/jn.00941.2003
EID:

2-s2.0-4344716921
Contributors: Otmakhov, N.; Khibnik, L.; Otmakhova, N.; Carpenter, S.; Riahi, S.; Asrican, B.; Lisman, J.
Source: Self-asserted source
Stephen Carpenter via Scopus - Elsevier

Persistent accumulation of calcium/calmodulin-dependent protein kinase II in dendritic spines after induction of NMDA receptor-dependent chemical long-term potentiation

Journal of Neuroscience
2004 | Journal article
DOI: 10.1523/JNEUROSCI.2350-04.2004
EID:

2-s2.0-7044270772
Contributors: Otmakhov, N.; Tao-Cheng, J.-H.; Carpenter, S.; Asrican, B.; Dosemeci, A.; Reese, T.S.; Lisman, J.
Source: Self-asserted source
Stephen Carpenter via Scopus - Elsevier

Peer review (13 reviews for 10 publications/grants)

Review activity for Cell reports. (1)
Review activity for Cell systems. (1)
Review activity for Clinical and translational medicine. (2)
Review activity for eLife (1)
Review activity for Journal of infectious diseases. (1)
Review activity for MBio. (1)
Review activity for Nature communications (1)
Review activity for Pathogens and disease / (1)
Review activity for PLOS pathogens : (2)
Review activity for Tuberculosis. (2)
How many people are using ORCID?