Personal information

Other IDs

Scopus Author ID: 59113538400

Keywords

depression hippocampus neuroinflammation mitochondrial

Countries

China

Biography

EDUCATION –
2005 –2008 Ph.D. , Physiology
Second Military Medical University,
2002 –2005 Master, Physiology
Second Military Medical University,
1996 –2001 Bachelor of Medicine
Anhui Medical University,
ACADEMIC APPOINTMENTS –
2012 – present Associate Professor
Department of Physiology， Second Military Medical University（Naval Medical University）
2008 – 2012 Lecturer
Department of Physiology， Second Military Medical University

Activities

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Works (22)

Chronic stress induces depression-like behavior in rats through affecting brain mitochondrial function and inflammation

Psychoneuroendocrinology
2025 | Journal article
DOI: 10.1016/j.psyneuen.2024.107261
EID:

2-s2.0-85212849924

Part of ISSN: 18733360 03064530
Contributors: Wang, L.; Xu, Y.; Jiang, M.; Wang, M.; Ji, M.; Xie, X.; Sheng, H.
Source: Self-asserted source
Hui via Scopus - Elsevier

Mitochondria in depression: The dysfunction of mitochondrial energy metabolism and quality control systems

CNS Neuroscience and Therapeutics
2024 | Journal article
DOI: 10.1111/cns.14576
EID:

2-s2.0-85184685169

Part of ISSN: 17555949 17555930
Contributors: Jiang, M.; Wang, L.; Sheng, H.
Source: Self-asserted source
Hui via Scopus - Elsevier

Spatial learning and memory deficits induced by prenatal glucocorticoid exposure depend on hippocampal CRHR1 and CXCL5 signaling in rats

Journal of Neuroinflammation
2021 | Journal article
DOI: 10.1186/s12974-021-02129-8
EID:

2-s2.0-85103852364

Part of ISSN: 17422094
Contributors: Zheng, Y.; Zhang, Y.-M.; Tang, Z.-S.; Du, J.-K.; Guo, D.-W.; Xu, Y.-J.; Sheng, H.; Lu, J.-Q.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

Treadmill Exercise Ameliorates Depression-Like Behavior in the Rats With Prenatal Dexamethasone Exposure: The Role of Hippocampal Mitochondria

Frontiers in Neuroscience
2019 | Journal article
DOI: 10.3389/fnins.2019.00264
EID:

2-s2.0-85101843329

Part of ISSN: 1662453X 16624548
Contributors: Wu, T.; Huang, Y.; Gong, Y.; Xu, Y.; Lu, J.; Sheng, H.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

Corticotropin-releasing hormone suppresses synapse formation in the hippocampus of male rats via inhibition of CXCL5 secretion by glia

Endocrinology
2018 | Journal article
DOI: 10.1210/en.2017-00336
EID:

2-s2.0-85046150743

Part of ISSN: 19457170 00137227
Contributors: Zhang, Y.; Zheng, Y.; Xu, Y.; Sheng, H.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

CRH/CRHR1 mediates prenatal synthetic glucocorticoid programming of depression-like behavior across 2 generations

FASEB Journal
2018 | Journal article
DOI: 10.1096/fj.201700948RR
EID:

2-s2.0-85050859226

Part of ISSN: 15306860 08926638
Contributors: Xu, Y.-J.; Sheng, H.; Wu, T.-W.; Bao, Q.-Y.; Zheng, Y.; Zhang, Y.-M.; Gong, Y.-X.; Lu, J.-Q.; You, Z.-D.; Xia, Y. et al.
Source: Self-asserted source
Hui via Scopus - Elsevier

Exercise amelioration of depression-like behavior in OVX mice is associated with suppression of NLRP3 inflammasome activation in hippocampus

Behavioural Brain Research
2016 | Journal article
DOI: 10.1016/j.bbr.2016.03.044
EID:

2-s2.0-84962032972

Part of ISSN: 18727549 01664328
Contributors: Wang, Y.; Xu, Y.; Sheng, H.; Ni, X.; Lu, J.
Source: Self-asserted source
Hui via Scopus - Elsevier

NLRP3 inflammasome activation mediates estrogen deficiency-induced depression- and anxiety-like behavior and hippocampal inflammation in mice

Brain, Behavior, and Immunity
2016 | Journal article
DOI: 10.1016/j.bbi.2016.02.022
EID:

2-s2.0-84959441405

Part of ISSN: 10902139 08891591
Contributors: Xu, Y.; Sheng, H.; Bao, Q.; Wang, Y.; Lu, J.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

Effect of exercise on estrogen deficiency-induced depression-like behavior and its inflammatory mechanisms

Academic Journal of Second Military Medical University
2015 | Journal article
DOI: 10.3724/SP.J.1008.2015.00477
EID:

2-s2.0-84930015729

Part of ISSN: 0258879X
Contributors: Bao, Q.Y.; Wang, Y.-J.; Xu, Y.-U.; Sheng, H.; Cao, M.-J.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

Inflammation and increased IDO in hippocampus contribute to depression-like behavior induced by estrogen deficiency

Behavioural Brain Research
2015 | Journal article
DOI: 10.1016/j.bbr.2015.04.017
EID:

2-s2.0-84928572182

Part of ISSN: 18727549 01664328
Contributors: Xu, Y.; Sheng, H.; Tang, Z.; Lu, J.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

Cardioprotection of 17β-estradiol against hypoxia/reoxygenation in cardiomyocytes is partly through up-regulation of CRH receptor type 2

Molecular and Cellular Endocrinology
2014 | Journal article
DOI: 10.1016/j.mce.2013.09.002
EID:

2-s2.0-84884540127

Part of ISSN: 03037207 18728057
Contributors: Cong, B.; Xu, Y.; Sheng, H.; Zhu, X.; Wang, L.; Zhao, W.; Tang, Z.; Lu, J.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

Exercise ameliorates depression-like behavior and increases hippocampal BDNF level in ovariectomized rats

Neuroscience Letters
2014 | Journal article
DOI: 10.1016/j.neulet.2014.04.053
EID:

2-s2.0-84901303007

Part of ISSN: 18727972 03043940
Contributors: Lu, J.; Xu, Y.; Hu, W.; Gao, Y.; Ni, X.; Sheng, H.; Liu, Y.
Source: Self-asserted source
Hui via Scopus - Elsevier

Swimming exercise ameliorates depression-like behavior in chronically stressed rats: Relevant to proinflammatory cytokines and IDO activation

Behavioural Brain Research
2013 | Journal article
DOI: 10.1016/j.bbr.2012.12.041
EID:

2-s2.0-84872534963

Part of ISSN: 01664328 18727549
Contributors: Liu, W.; Sheng, H.; Xu, Y.; Liu, Y.; Lu, J.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

Activation of CRHR2 exerts an inhibitory effect on the expression of collapsin response mediator protein 3 in hippocampal neurons

Neuropeptides
2012 | Journal article
DOI: 10.1016/j.npep.2011.12.004
EID:

2-s2.0-84862779311

Part of ISSN: 01434179 15322785
Contributors: Chen, Y.; Sheng, H.; Xu, Y.; Zhang, Y.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

Corticotropin-releasing hormone stimulates mitotic kinesin-like protein 1 expression via a PLC/PKC-dependent signaling pathway in hippocampal neurons

Molecular and Cellular Endocrinology
2012 | Journal article
DOI: 10.1016/j.mce.2012.06.003
EID:

2-s2.0-84865284186

Part of ISSN: 03037207 18728057
Contributors: Sheng, H.; Xu, Y.; Chen, Y.; Zhang, Y.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

CRH-R1 and CRH-R2 differentially modulate dendritic outgrowth of hippocampal neurons

Endocrine
2012 | Journal article
DOI: 10.1007/s12020-012-9603-5
EID:

2-s2.0-84862786393

Part of ISSN: 15590100 1355008X
Contributors: Sheng, H.; Xu, Y.; Chen, Y.; Zhang, Y.; Xu, X.; He, C.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

Glucocorticoid acts on a putative g protein-coupled receptor to rapidly regulate the activity of NMDA receptors in hippocampal neurons

American Journal of Physiology - Endocrinology and Metabolism
2012 | Journal article
DOI: 10.1152/ajpendo.00302.2011
EID:

2-s2.0-84859476554

Part of ISSN: 01931849 15221555
Contributors: Zhang, Y.; Sheng, H.; Qi, J.; Ma, B.; Sun, J.; Li, S.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

Swimming exercise ameliorates depression-like behaviors induced by prenatal exposure to glucocorticoids in rats

Neuroscience Letters
2012 | Journal article
DOI: 10.1016/j.neulet.2012.07.011
EID:

2-s2.0-84865161526

Part of ISSN: 03043940 18727972
Contributors: Liu, W.; Xu, Y.; Lu, J.; Zhang, Y.; Sheng, H.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

Regulatory effect of corticotrophin-releasing hormone on glutamate-mediated current in cultured hippocampal neurons

Academic Journal of Second Military Medical University
2009 | Journal article
DOI: 10.3724/SP.J..1008.2009.00233
EID:

2-s2.0-63249089035

Part of ISSN: 0258879X
Contributors: Sheng, H.; Ma, B.; Lü, J.-Q.; Sun, T.-T.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

Corticotropin-releasing hormone (CRH) depresses N-methyl-D-aspartate receptor-mediated current in cultured rat hippocampal neurons via CRH receptor type 1

Endocrinology
2008 | Journal article
DOI: 10.1210/en.2007-1378
EID:

2-s2.0-40849140968

Part of ISSN: 00137227 00137227
Contributors: Sheng, H.; Zhang, Y.; Sun, J.; Gao, L.; Ma, B.; Lu, J.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

Corticotropin-releasing hormone stimulates SGK-1 kinase expression in cultured hippocampal neurons via CRH-R1

American Journal of Physiology - Endocrinology and Metabolism
2008 | Journal article
DOI: 10.1152/ajpendo.90462.2008
EID:

2-s2.0-56049086401

Part of ISSN: 01931849 15221555
Contributors: Sheng, H.; Sun, T.; Cong, B.; He, P.; Zhang, Y.; Yan, J.; Lu, C.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier

Glucocorticoid exposure of pregnant rats influences hippocampus SGK expression in rat offsprings

Academic Journal of Second Military Medical University
2008 | Journal article
DOI: 10.3724/SP.J.1008.2008.01495
EID:

2-s2.0-58149291819

Part of ISSN: 0258879X
Contributors: Cong, B.-H.; Li, Y.-H.; Sun, T.-T.; Zhu, X.-Y.; Wen, J.-N.; Hu, J.; Sheng, H.; Ni, X.
Source: Self-asserted source
Hui via Scopus - Elsevier
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