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Employment (3)

University of Edinburgh: Edinburgh, GB

2023-05-01 to present | Chancellor's Fellow (Center for Inflammation Research)
Employment
Source: Self-asserted source
Konrad Rawlik

University of Edinburgh: Edinburgh, GB

2022-01-03 to 2023-05-01 | Data Curation Project Analyst (The Roslin Institute )
Employment
Source: Self-asserted source
Konrad Rawlik

University of Edinburgh: Edinburgh, GB

2013-05-01 to 2022-02-28 | Core Scientist (Research Fellow) (The Roslin Institute )
Employment
Source: Self-asserted source
Konrad Rawlik

Education and qualifications (3)

University of Edinburgh: Edinburgh, GB

2008 to 2012 | PhD in Machine Learning (School of Informatics)
Education
Source: Self-asserted source
Konrad Rawlik

University of Edinburgh: Edinburgh, GB

2007 to 2008 | MRes in Neuroinformatics (School of Informatics)
Education
Source: Self-asserted source
Konrad Rawlik

University of Edinburgh: Edinburgh, GB

2003 to 2007 | BSc in Mathematics and Artificial Intelligence (School of Mathematics)
Education
Source: Self-asserted source
Konrad Rawlik

Funding (3)

MRC: Edinburgh Molecular Mechanisms Cluster

2024-03 to 2028-03 | Grant
Medical Research Council (London, GB)
GRANT_NUMBER:

MR/Y030877/1
Source: Self-asserted source
Konrad Rawlik

Artificial Intelligence and Multimorbidity: Clustering in Individuals, Space and Clinical Context (AIM-CISC)

2021-08 to 2024-08 | Grant
National Institute for Health Research (London, GB)
URL: https://www.ed.ac.uk/usher/aim-cisc
GRANT_NUMBER: NIHR202639
Source: Self-asserted source
Konrad Rawlik

Understanding disease through environment-wide association studies

2017-07-31 to 2020-07-30 | Grant
Medical Research Council (London, GB)
URL: https://app.dimensions.ai/details/grant/grant.7085028
GRANT_NUMBER: MR/P015514/1
Source: Self-asserted source
Konrad Rawlik via DimensionsWizard

Works (50)

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Nature
2023-05-25 | Journal article
DOI: 10.1038/s41586-023-06034-3
Contributors: Erola Pairo-Castineira; Konrad Rawlik; Andrew D. Bretherick; Ting Qi; Yang Wu; Isar Nassiri; Glenn A. McConkey; Marie Zechner; Lucija Klaric; Fiona Griffiths et al.
Source: check_circle
Crossref

Fine-mapping of retinal vascular complexity loci identifies Notch regulation as a shared mechanism with myocardial infarction outcomes

Communications Biology
2023-05-15 | Journal article
DOI: 10.1038/s42003-023-04836-9
Contributors: Ana Villaplana-Velasco; Marie Pigeyre; Justin Engelmann; Konrad Rawlik; Oriol Canela-Xandri; Claire Tochel; Frida Lona-Durazo; Muthu Rama Krishnan Mookiah; Alex Doney; Esteban J. Parra et al.
Source: check_circle
Crossref

Adeno-associated virus 2 infection in children with non-A-E hepatitis.

Nature
2023-03 | Journal article
DOI: 10.1038/s41586-023-05948-2
PMID: 36996873
Contributors: Ho A; Orton R; Tayler R; Asamaphan P; Herder V; Davis C; Tong L; Smollett K; Manali M; Allan J et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Reply to: Genotype by sex interactions in ankylosing spondylitis

Nature Genetics
2023-01 | Journal article
DOI: 10.1038/s41588-022-01251-4
Contributors: Elena Bernabeu; Konrad Rawlik; Oriol Canela-Xandri; Andrea Talenti; James Prendergast; Albert Tenesa
Source: check_circle
Crossref

A compendium of genetic regulatory effects across pig tissues

2022-11 | Preprint
DOI: 10.21203/rs.3.rs-2261680/v1
PPR: PPR575923
Contributors: Fang L; Teng J; Gao Y; Yin H; Bai Z; Liu S; Zeng H; Bai L; Cai Z; Zhao B et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Frequency and Phenotype Associations of Rare Variants in 5 Monogenic Cerebral Small Vessel Disease Genes in 200,000 UK Biobank Participants

Neurology Genetics
2022-10 | Journal article
DOI: 10.1212/NXG.0000000000200015
Contributors: Amy Christina Ferguson; Sophie Thrippleton; David Henshall; Ed Whittaker; Bryan Conway; Malcolm MacLeod; Rainer Malik; Konrad Rawlik; Albert Tenesa; Cathie Sudlow et al.
Source: check_circle
Crossref

A multi-tissue atlas of regulatory variants in cattle.

Nature genetics
2022-08 | Journal article
DOI: 10.1038/s41588-022-01153-5
PMID: 35953587
PMC: PMC7613894
Contributors: Liu S; Gao Y; Canela-Xandri O; Wang S; Yu Y; Cai W; Li B; Xiang R; Chamberlain AJ; Pairo-Castineira E et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Comparative transcriptome in large-scale human and cattle populations.

Genome biology
2022-08 | Journal article
DOI: 10.1186/s13059-022-02745-4
PMID: 35996157
PMC: PMC9394047
Contributors: Yao Y; Liu S; Xia C; Gao Y; Pan Z; Canela-Xandri O; Khamseh A; Rawlik K; Wang S; Li B et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Whole-genome sequencing reveals host factors underlying critical COVID-19

Nature
2022-07-07 | Journal article
DOI: 10.1038/s41586-022-04576-6
Contributors: Athanasios Kousathanas; Erola Pairo-Castineira; Konrad Rawlik; Alex Stuckey; Christopher A. Odhams; Susan Walker; Clark D. Russell; Tomas Malinauskas; Yang Wu; Jonathan Millar et al.
Source: check_circle
Crossref

Genetic Landscape of the ACE2 Coronavirus Receptor.

Circulation
2022-04 | Journal article
DOI: 10.1161/circulationaha.121.057888
PMID: 35387486
PMC: PMC9047645
Contributors: Yang Z; Macdonald-Dunlop E; Chen J; Zhai R; Li T; Richmond A; Klarić L; Pirastu N; Ning Z; Zheng C et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

GWAS and meta-analysis identifies multiple new genetic mechanisms underlying severe Covid-19

2022-03-07 | Preprint
DOI: 10.1101/2022.03.07.22271833
Contributors: Erola Pairo-Castineira; Konrad Rawlik; Lucija Klaric; Athanasios Kousathanas; Anne Richmond; Jonathan Millar; Clark D Russell; Tomas Malinauskas; Ryan Thwaites; Alex Stuckey et al.
Source: check_circle
Crossref

Physician-Confirmed and Administrative Definitions of Stroke in UK Biobank Reflect the Same Underlying Genetic Trait.

Frontiers in neurology
2022-02 | Journal article
DOI: 10.3389/fneur.2021.787107
PMID: 35185750
PMC: PMC8847736
Contributors: Rannikmäe K; Rawlik K; Ferguson AC; Avramidis N; Jiang M; Pirastu N; Shen X; Davidson E; Woodfield R; Malik R et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Expanded Analysis of Pigmentation Genetics in UK Biobank

2022-01-31 | Preprint
DOI: 10.1101/2022.01.30.478418
Contributors: Erola Pairo-Castineira; Jaime Cornelissen; Konrad Rawlik; Oriol Canela-Xandri; Stacie K. Loftus; William J. Pavan; Kevin M. Brown; Albert Tenesa; Ian J. Jackson
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Crossref

Decreased retinal vascular complexity is an early biomarker of MI supported by a shared genetic control

2021-12-16 | Preprint
DOI: 10.1101/2021.12.16.21267446
Contributors: Ana Villaplana-Velasco; Justin Engelmann; Konrad Rawlik; Oriol Canela-Xandri; Claire Tochel; Frida Lona-Durazo; Muthu Rama Krishnan Mookiah; Alex Doney; Esteban J. Parra; Emanuele Trucco et al.
Source: check_circle
Crossref

Frequency and phenotype associations of rare variants in five monogenic cerebral small vessel disease genes in 200,000 UK Biobank participants with whole exome sequencing data

2021-11 | Preprint
DOI: 10.1101/2021.11.17.21266447
PPR: PPR421138
Contributors: Ferguson AC; Thrippleton S; Henshall DE; Whittaker E; Conway B; MacLeod M; Malik R; Rawlik K; Tenesa A; Sudlow C et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4.

Nature communications
2021-11 | Journal article
DOI: 10.1038/s41467-021-26783-x
PMID: 34785669
PMC: PMC8595373
Contributors: Grosche S; Marenholz I; Esparza-Gordillo J; Arnau-Soler A; Pairo-Castineira E; Rüschendorf F; Ahluwalia TS; Almqvist C; Arnold A; Lee YA
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Physician-confirmed and administrative definitions of stroke in UK Biobank reflect the same underlying genetic trait

2021-10 | Preprint
DOI: 10.1101/2021.09.30.21264348
PPR: PPR403308
Contributors: Rannikmäe K; Rawlik K; Ferguson AC; Avramidis N; Jiang M; Pirastu N; Shen X; Davidson E; Woodfield R; Malik R et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Sex differences in genetic architecture in the UK Biobank

Nature Genetics
2021-09 | Journal article
DOI: 10.1038/s41588-021-00912-0
Contributors: Elena Bernabeu; Oriol Canela-Xandri; Konrad Rawlik; Andrea Talenti; James Prendergast; Albert Tenesa
Source: check_circle
Crossref

Whole genome sequencing identifies multiple loci for critical illness caused by COVID-19

2021-09-02 | Other
DOI: 10.1101/2021.09.02.21262965
Contributors: Athanasios Kousathanas; Erola Pairo-Castineira; Konrad Rawlik; Alex Stuckey; Christopher A Odhams; Susan Walker; Clark D Russell; Tomas Malinauskas; Jonathan Millar; Katherine S Elliott et al.
Source: check_circle
Crossref

Mapping the human genetic architecture of COVID-19.

Nature
2021-07 | Journal article
DOI: 10.1038/s41586-021-03767-x
PMID: 34237774
PMC: PMC8674144
Contributors: COVID-19 Host Genetics Initiative
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Birth weight associations with DNA methylation differences in an adult population

Epigenetics
2021-07-03 | Journal article
DOI: 10.1080/15592294.2020.1827713
Contributors: Rebecca A. Madden; Daniel L. McCartney; Rosie M. Walker; Robert F. Hillary; Mairead L. Bermingham; Konrad Rawlik; Stewart W. Morris; Archie Campbell; David J. Porteous; Ian J. Deary et al.
Source: check_circle
Crossref

Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals.

American journal of human genetics
2021-06 | Journal article
DOI: 10.1016/j.ajhg.2021.05.017
PMID: 34115965
PMC: PMC8173480
Contributors: Kosmicki JA; Horowitz JE; Banerjee N; Lanche R; Marcketta A; Maxwell E; Bai X; Sun D; Backman JD; Sharma D et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles.

Genome medicine
2021-01 | Journal article
DOI: 10.1186/s13073-020-00808-4
PMID: 33397400
PMC: PMC7784364
Contributors: Walker RM; Vaher K; Bermingham ML; Morris SW; Bretherick AD; Zeng Y; Rawlik K; Amador C; Campbell A; Haley CS et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

A comprehensive catalogue of regulatory variants in the cattle transcriptome

2020-12 | Preprint
DOI: 10.1101/2020.12.01.406280
PPR: PPR247327
Contributors: Liu S; Gao Y; Canela-Xandri O; Wang S; Yu Y; Cai W; Li B; Xiang R; Chamberlain AJ; Pairo-Castineira E et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Evidence of horizontal indirect genetic effects in humans

Nature Human Behaviour
2020-12-14 | Journal article
DOI: 10.1038/s41562-020-00991-9
Contributors: Charley Xia; Oriol Canela-Xandri; Konrad Rawlik; Albert Tenesa
Source: check_circle
Crossref

Genetic mechanisms of critical illness in Covid-19

2020-09-25 | Other
DOI: 10.1101/2020.09.24.20200048
Contributors: Erola Pairo-Castineira; Sara Clohisey; Lucija Klaric; Andrew Bretherick; Konrad Rawlik; Nick Parkinson; Dorota Pasko; Susan Walker; Anne Richmond; Max Head Fourman et al.
Source: check_circle
Crossref

SNP heritability: What are we estimating?

2020-09-16 | Preprint
DOI: 10.1101/2020.09.15.276121
Contributors: Konrad Rawlik; Oriol Canela-Xandri; John Woolliams; Albert Tenesa
Source: check_circle
Crossref

Epigenome-wide analyses identify DNA methylation signatures of dementia risk.

Alzheimer's & dementia (Amsterdam, Netherlands)
2020-08 | Journal article
DOI: 10.1002/dad2.12078
PMID: 32789163
PMC: PMC7416667
Contributors: Walker RM; Bermingham ML; Vaher K; Morris SW; Clarke TK; Bretherick AD; Zeng Y; Amador C; Rawlik K; Pandya K et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Sexual differences in genetic architecture in UK Biobank

2020-07 | Preprint
DOI: 10.1101/2020.07.20.211813
PPR: PPR190429
Contributors: Bernabeu E; Canela-Xandri O; Rawlik K; Talenti A; Prendergast J; Tenesa A
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits

PLOS Genetics
2020-07-06 | Journal article
DOI: 10.1371/journal.pgen.1008785
Contributors: Andrew D. Bretherick; George Davey Smith; Oriol Canela-Xandri; Peter K. Joshi; David W. Clark; Konrad Rawlik; Thibaud S. Boutin; Yanni Zeng; Carmen Amador; Pau Navarro et al.
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Crossref

Comprehensive analyses of 723 transcriptomes enhance genetic and biological interpretations for complex traits in cattle.

Genome research
2020-05 | Journal article
DOI: 10.1101/gr.250704.119
PMID: 32424068
PMC: PMC7263193
Contributors: Fang L; Cai W; Liu S; Canela-Xandri O; Gao Y; Jiang J; Rawlik K; Li B; Schroeder SG; Rosen BD et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Epigenome-wide analyses identify DNA methylation signatures of dementia risk

2020-04 | Preprint
DOI: 10.1101/2020.04.06.20055517
PPR: PPR150155
Contributors: Walker RM; Bermingham ML; Vaher K; Morris SW; Clarke T; Bretherick AD; Zeng Y; Amador C; Rawlik K; Pandya K et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Statistical and Functional Studies Identify Epistasis of Cardiovascular Risk Genomic Variants From Genome‐Wide Association Studies

Journal of the American Heart Association
2020-04-09 | Journal article
DOI: 10.1161/JAHA.119.014146
Contributors: Yabo Li; Hyosuk Cho; Fan Wang; Oriol Canela‐Xandri; Chunyan Luo; Konrad Rawlik; Stephen Archacki; Chengqi Xu; Albert Tenesa; Qiuyun Chen et al.
Source: check_circle
Crossref

Identification of epigenome-wide DNA methylation differences between carriers of <i>APOE</i> ε4 and <i>APOE</i> ε2

2019-10 | Preprint
DOI: 10.1101/815035
PPR: PPR99603
Contributors: Walker RM; Vaher K; Bermingham ML; Morris SW; Bretherick AD; Zeng Y; Rawlik K; Amador C; Campbell A; Haley CS et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Birth weight associations with psychiatric and physical health, cognitive function, and DNA methylation differences in an adult population

2019-06 | Preprint
DOI: 10.1101/664045
PPR: PPR81409
Contributors: Madden RA; McCartney DL; Walker RM; Hillary RF; Bermingham ML; Rawlik K; Morris SW; Campbell A; Porteous DJ; Deary IJ et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Proteome-by-phenome Mendelian Randomisation detects 38 proteins with causal roles in human diseases and traits

2019-05 | Preprint
DOI: 10.1101/631747
PPR: PPR78757
Contributors: Bretherick AD; Canela-Xandri O; Joshi PK; Clark DW; Rawlik K; Boutin TS; Zeng Y; Amador C; Navarro P; Rudan I et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD.

EBioMedicine
2019-03 | Journal article
DOI: 10.1016/j.ebiom.2019.03.072
PMID: 30935889
PMC: PMC6557748
Contributors: Bermingham ML; Walker RM; Marioni RE; Morris SW; Rawlik K; Zeng Y; Campbell A; Redmond P; Whalley HC; Adams MJ et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Parent of origin genetic effects on methylation in humans are common and influence complex trait variation.

Nature communications
2019-03 | Journal article
DOI: 10.1038/s41467-019-09301-y
PMID: 30918249
PMC: PMC6437195
Contributors: Zeng Y; Amador C; Xia C; Marioni R; Sproul D; Walker RM; Morris SW; Bretherick A; Canela-Xandri O; Boutin TS et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability

Nature Communications
2018-12-10 | Journal article
DOI: 10.1038/s41467-018-07691-z
Contributors: Michael D. Morgan; Erola Pairo-Castineira; Konrad Rawlik; Oriol Canela-Xandri; Jonathan Rees; David Sims; Albert Tenesa; Ian J. Jackson
Source: check_circle
Crossref

An atlas of genetic associations in UK Biobank

Nature Genetics
2018-11 | Journal article
DOI: 10.1038/s41588-018-0248-z
Contributors: Oriol Canela-Xandri; Konrad Rawlik; Albert Tenesa
Source: check_circle
Crossref

Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD

2018-11 | Preprint
DOI: 10.1101/473629
PPR: PPR62511
Contributors: Bermingham ML; Walker RM; Marioni RE; Morris SM; Rawlik K; Zeng Y; Campbell A; Redmond P; Whalley HC; Adams MJ et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

The genetic architecture of hair colour in the UK population

2018-05 | Preprint
DOI: 10.1101/320267
PPR: PPR12995
Contributors: Morgan MD; Pairo-Castineira E; Rawlik K; Canela-Xandri O; Rees J; Sims D; Tenesa A; Jackson IJ
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Indirect assortative mating for human disease and longevity

2017-09-07 | Preprint
DOI: 10.1101/185207
Contributors: Konrad Rawlik; Oriol Canela-Xandri; Albert Tenesa
Source: check_circle
Crossref

Evidence of epigenetic admixture in the Colombian population.

Human molecular genetics
2017-02 | Journal article
DOI: 10.1093/hmg/ddw407
PMID: 28073928
PMC: PMC5409088
Contributors: Rawlik K; Rowlatt A; Sanabria-Salas MC; Hernández-Suárez G; Serrano López ML; Zabaleta J; Tenesa A
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

IL1B-CGTC haplotype is associated with colorectal cancer in admixed individuals with increased African ancestry.

Scientific reports
2017-02 | Journal article
DOI: 10.1038/srep41920
PMID: 28157220
PMC: PMC5291207
Contributors: Sanabria-Salas MC; Hernández-Suárez G; Umaña-Pérez A; Rawlik K; Tenesa A; Serrano-López ML; Sánchez de Gómez M; Rojas MP; Bravo LE; Albis R et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Improved Genetic Profiling of Anthropometric Traits Using a Big Data Approach

PLOS ONE
2016-12-15 | Journal article
DOI: 10.1371/journal.pone.0166755
Contributors: Oriol Canela-Xandri; Gregory S. Barsh; Konrad Rawlik; John A. Woolliams; Albert Tenesa
Source: check_circle
Crossref

Evaluating the contribution of genetics and familial shared environment to common disease using the UK Biobank.

Nature genetics
2016-07 | Journal article
DOI: 10.1038/ng.3618
PMID: 27428752
PMC: PMC5989924
Contributors: Muñoz M; Pong-Wong R; Canela-Xandri O; Rawlik K; Haley CS; Tenesa A
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Evidence for sex-specific genetic architectures across a spectrum of human complex traits.

Genome biology
2016-07 | Journal article
DOI: 10.1186/s13059-016-1025-x
PMID: 27473438
PMC: PMC4965887
Contributors: Rawlik K; Canela-Xandri O; Tenesa A
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

Imputation of DNA Methylation Levels in the Brain Implicates a Risk Factor for Parkinson's Disease.

Genetics
2016-07 | Journal article
DOI: 10.1534/genetics.115.185967
PMID: 27466229
PMC: PMC5068861
Contributors: Rawlik K; Rowlatt A; Tenesa A
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central

The heritability and patterns of DNA methylation in normal human colorectum.

Human molecular genetics
2016-03 | Journal article
DOI: 10.1093/hmg/ddw072
PMID: 26936820
PMC: PMC5181623
Contributors: Rowlatt A; Hernández-Suárez G; Sanabria-Salas MC; Serrano-López M; Rawlik K; Hernandez-Illan E; Alenda C; Castillejo A; Soto JL; Haley CS et al.
Source: Self-asserted source
Konrad Rawlik via Europe PubMed Central
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