Personal information

Emails & domains

Verified email domains

Websites & social links

UCL IRIS Profile
UCLH Consultant Profile
Director of EGA Institute for Women's Health
LinkedIn
Twitter

Other IDs

SciProfiles: 2842667
Scopus Author ID: 7402605276

Keywords

fetal diagnosis & therapy, preterm birth, fetal growth restriction, preconception health, pregnancy therapeutics

Countries

United Kingdom

Biography

Anna is Professor, Honorary Consultant in Obstetrics and Maternal Fetal Medicine, Director of the Elizabeth Garrett Anderson Institute for Women’s Health, University College London (UCL) and Deputy Director of the Tommy's National Centre for Preterm Birth Research.
Her main research is in translational medicine. She leads the UCL Centre for Prenatal Therapy whose aim is to develop treatments for life threatening disorders such as congenital diseases and obstetric complications such as fetal growth restriction, stillbirth and preterm birth.
She coordinated the introduction of open fetal surgery for spina bifida to the UK at UCLHospital in 2018, which is now one of two NHS England commissioned fetal surgery centres that has been recommissioned for a further 5 years in 2023.
In the last 5 years she has been funded over £40 million, £8 million as PI and £32 million as co-applicant in translational medicine from the European Commission, Wellcome Trust, EPSRC, NIHR, MRC, Action Medical Research, Sparks, Wellbeing of Women and Rosetrees Trust.
She led an international consensus to develop the first terminology to define and grade maternal and fetal adverse events for clinical trials in pregnancy: MFAET.

Activities

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Employment (10)

University College London: London, London, GB

2018-04-01 to present | Director (EGA Institute for Women's Health, Faculty of Population Health Sciences)
Employment
Source: Self-asserted source
Anna David

University College London: London, GB

2016-06-17 to present | Professor in Obstetrics and Maternal Fetal Medicine (EGA Institute for Women's Health)
Employment
Source: Self-asserted source
Anna David

University College London Hospital NHS Foundation Trust: LONDON, Please select region, state or province, GB

2008-05-05 to present | Consultant in Obstetrics and Maternal Fetal Medicine (Women's Health Division)
Employment
Source: Self-asserted source
Anna David

University College London: London, GB

2012-06-18 to 2016-06-16 | Reader in Obstetrics and Maternal Fetal Medicine (EGA Institute for Women's Health)
Employment
Source: Self-asserted source
Anna David

University College London: London, GB

2008-05-05 to 2012-06-17 | NIHR Senior Lecturer in Obstetrics and Maternal Fetal Medicine (EGA Institute for Women's Health)
Employment
Source: Self-asserted source
Anna David

University College London: London, GB

2004-11 to 2008-05-04 | Clinical Lecturer in Obstetrics and Gynaecology (EGA Institute for Women's Health)
Employment
Source: Self-asserted source
Anna David

University College London: London, GB

2000-03 to 2004-11 | Clinical Academic Training Fellow in Fetal Medicine (Obstetrics and Gynaecology)
Employment
Source: Self-asserted source
Anna David

Queen Charlotte's and Chelsea Hospital: London, London, GB

1999-03 to 2000-03 | Specialist Registrar Year 3 (Obstetrics and Gynaecology)
Employment
Source: Self-asserted source
Anna David

West Middlesex University Hospital: Isleworth, GB

1998-03 to 1999-03 | Specialist Registrar year 2 (Obstetrics and Gynaecology)
Employment
Source: Self-asserted source
Anna David

Ealing Hospital: Southall, GB

1997-03 to 1998-03 | Specialist Registrar year 1 (Obstetrics and Gynaecology)
Employment
Source: Self-asserted source
Anna David

Education and qualifications (7)

Royal College of Obstetricians and Gynaecologists: London, London, GB

2016-06-06 to present | FRCOG
Qualification
Source: Self-asserted source
Anna David

Royal College of Obstetricians and Gynaecologists: London, London, GB

2008-04-24 to present | Certificate of Subspecialty Training in Maternal Fetal Medicine
Qualification
Source: Self-asserted source
Anna David

General Medical Council: London, London, GB

2008-04-24 to present | Certificate of Specialty Training in Obstetrics & Gynaecology
Qualification
Source: Self-asserted source
Anna David

University College London: London, London, GB

2005-05-04 to present | PhD in Fetal Medicine (Institute for Women's Health)
Qualification
Source: Self-asserted source
Anna David

Royal College of Obstetricians and Gynaecologists: London, GB

1998-05 to present | MRCOG
Qualification
Source: Self-asserted source
Anna David

University of Manchester Manchester Medical School: Manchester, Manchester, GB

1989 to 1992 | MB ChB
Education
Source: Self-asserted source
Anna David

University of St Andrews: St Andrews, Scotland, GB

1985-09 to 1989-07 | 1st class BSc Hons Medical Sciences
Education
Source: Self-asserted source
Anna David

Professional activities (20)

NIHR University College London Hospitals Biomedical Research Centre: London, London, GB

2024-05 to present | Lead for Women's Health shadow theme
Service
Source: Self-asserted source
Anna David

National Institute for Health and Care Excellence: London, London, GB

2019-06-05 to present | Specialist Adviser to Interventional Procedures Programme
Service
Source: Self-asserted source
Anna David

UK Preconception Partnership: London, London, GB

2018-07 to present | Founding Member
Membership
Source: Self-asserted source
Anna David

NHS England Specialised Services: London, London, GB

2017-10-01 to present | Member of NHS England Specialised Services Fetal Surgery for Myelomeningocoele Working Group
Membership
Source: Self-asserted source
Anna David

KU Leuven: Leuven, BE

2017-08-03 to present | Visiting Professor of Fetal Medicine (Department of Development and Regeneration)
Invited position
Source: Self-asserted source
Anna David

International Society for Prenatal Diagnosis: Charlottesville, VA, US

2017-07-16 to present | Co-Chair of Fetal Therapy Special Interest Group
Service
Source: Self-asserted source
Anna David

International Fetal Medicine and Surgery Society: London, London, GB

2015-07-05 to present | Member
Membership
Source: Self-asserted source
Anna David

International Fetal Transplantation and Immunology Society: Winston Salem, North Carolina, US

2014-04-04 to present | Founder Member
Membership
Source: Self-asserted source
Anna David

National Reproductive Health Research Network: London, London, GB

2009-05-03 to present | Member of Clinical Study Group in Fetal Medicine
Service
Source: Self-asserted source
Anna David

International Society for Prenatal Diagnosis: Charlottesville, VA, US

2008-05-01 to present | Member
Membership
Source: Self-asserted source
Anna David

Society for Reproductive Investigation: Milwaukee, Wisconsin, US

2001-03-01 to present | Member
Membership
Source: Self-asserted source
Anna David

British Maternal Fetal Medicine Society: London, London, GB

2000-03-01 to present | Member
Membership
Source: Self-asserted source
Anna David

International Society for Prenatal Diagnosis: Charlottesville, VA, US

2024-09-01 | Board of Directors
Distinction
Source: Self-asserted source
Anna David

Tommy’s National Centre for Preterm Birth Research: London, London, GB

2023-09 | Deputy Director
Distinction
Source: Self-asserted source
Anna David

Tommy's: London, London, GB

2015-02-01 to 2023-07-01 | Scientific Trustee of Tommy's Charity
Service
Source: Self-asserted source
Anna David

Advisory Committee on Clinical Impact Awards (ACCIO): London, London, GB

2023-04 | National NHS Bronze Clinical Impact Award
Distinction
Source: Self-asserted source
Anna David

British Medical Association: London, London, GB

2021-01 | BMA Role model for Women in Academic Medicine
Distinction
Source: Self-asserted source
Anna David

Prenatal Diagnosis journal: Chichester, GB

2017-07-15 to 2020-12-08 | Member of Editorial Board
Service
Source: Self-asserted source
Anna David

British Medical Journal: London, London, GB

2019-05 | Clinical Leadership Team for Fetal Surgery at BMJ Awards
Distinction
Source: Self-asserted source
Anna David

Advisory Committee on Clinical Excellence Awards (ACCEA): London, London, GB

2018-04 | National ACCEA Bronze Clinical Excellence Award
Distinction
Source: Self-asserted source
Anna David

Funding (67)

Borne Uterine Mapping Project

2023-11 to 2024-10 | Grant
Borne Charity (London, GB)
Source: Self-asserted source
Anna David

Organ maturation in preparation for birth

2023-11 to 2024-10 | Grant
Chan Zuckerberg Initiative (United States) (Redwood City, US)
Source: Self-asserted source
Anna David

PROSPEKT: Prevention of Stillbirth using Optical Technologies and Knowledge Transfer

2022-11 to 2025-10 | Grant
Wellcome Leap (CA, CA, US)
Source: Self-asserted source
Anna David

MICA: MRC EVERREST: A Pre-clinical Efficacy Study for FGR

2022-05 to 2024-07 | Grant
Medical Research Council (London, GB)
Source: Self-asserted source
Anna David

Rotation of the fetal head at full cervical dilatation

2021-06 to 2025-08 | Grant
National Institute for Health Research (London, London, GB)
Source: Self-asserted source
Anna David

Fetoscopic repair of fetal spina bifida and tracheal occlusion for congental diaphragmatic hernia

2020-11 to 2025-10 | Grant
University College London Hospital Charity (London, London, GB)
Source: Self-asserted source
Anna David

COVID-19: Assessing the vulnerability of the fetus to SARS-CoV2 infection across development

2020-06 to 2021-05 | Grant
UK Research and Innovation (London, Please Select, GB)
Source: Self-asserted source
Anna David

Risk of preterm birth in women who conceive following bone marrow transplantation in childhood

2020-01 to 2021-07 | Grant
Action Medical Research (Horsham, Sussex, GB)
Source: Self-asserted source
Anna David

Centre for Doctoral Training in Intelligent, Integrated Imaging In Healthcare (i4health).

2019-09 to 2024-08 | Grant
UK Research and Innovation (London, GB)
Source: Self-asserted source
Anna David

PREDICT study: Predicting preterm birth after surgical intervention in twin pregnancies

2019-09 to 2021-08 | Grant
Twins Trust (Aldershot, Hampshire, GB)
Source: Self-asserted source
Anna David

Combining iPSC and gene editing with cell therapy to develop the next generation of MSC-based therapeutics to counteract bone fragility in Osteogenesis Imperfecta

2019-09 to 2021-04 | Grant
Medical Research Council (London, London, GB)
Source: Self-asserted source
Anna David

CeRclarge After Full-dilatation caesarean-secTion

2019-06 to 2021-11 | Grant
JP Moulton Charitable Trust (Bradford, GB)
Source: Self-asserted source
Anna David

An innovative bioengineering approach to heal the fetal membranes after iatrogenic Preterm Premature Rupture of the Membranes (PPROM)

2018-02 to 2021-01 | Grant
Sparks/GOSH Charity 17QMU01 (London, London, GB)
Source: Self-asserted source
Anna David

European Prematurity Research Centre (with Imperial College)

2018-01 to 2022-12 | Grant
March of Dimes Foundation (VA, VA, US)
Source: Self-asserted source
Anna David

Advanced MRI for the assessment of placental perfusion in intrauterine growth restriction

2017-10 to 2019-09 | Grant
Radiological Research Trust (London, London, GB)
Source: Self-asserted source
Anna David

Wellcome Trust Centre for Surgical and Interventional Sciences

2017-05 to 2022-04 | Grant
Wellcome Trust (London, London, GB)
Source: Self-asserted source
Anna David

Rare inherited and congenital diseases (ERNICA): Rare-complex gastrointestinal diseases

2017-03 to present | Grant
European Reference Network (London, London, GB)
Source: Self-asserted source
Anna David

Early pregnancy cervical immune competence evaluation for the stratification of preterm birth risk

2016-12 to 2018-04 | Grant
Action Medical Research (Horsham, Sussex, GB)
Source: Self-asserted source
Anna David

Funding fetoscopic balloon placement for tracheal occlusion to treat congenital diaphragmatic hernia

2016-11 to 2018-10 | Grant
CDH-UK Charity (Kings Lynn, GB)
Source: Self-asserted source
Anna David

Developing new tests to predict outcome in placental insufficiency and fetal growth restriction

2016-09 to 2021-12 | Grant
The Mitchell Charitable Trust (London, London, GB)
Source: Self-asserted source
Anna David

IMPPICT: Identifying Markers of Prognosis in Placental Insufficiency to optimise participation in Clinical Trials of potential therapeutics

2016-09 to 2021-12 | Grant
Rosetrees Trust (London, London, GB)
Source: Self-asserted source
Anna David

Demonstrating functional haematopoiesis of human gene corrected amniotic fluid derived stem cells for therapeutic purposes

2016-09 to 2018-01 | Grant
Medical Research Council (London, GB)
Source: Self-asserted source
Anna David

Development of an in utero approach for thalassaemia gene therapy

2016-06 to 2018-06 | Grant
UK Thalassemia Society (London, London, GB)
Source: Self-asserted source
Anna David

In utero correction of fetal spina bifida

2016-06 to 2018-06 | Grant
University College London Hospital Charities (London, London, GB)
Source: Self-asserted source
Anna David

Boost Brittle Bones Before Birth (BOOSTB4). A phase I/IIa clinical trial of in utero and postnatal stem cell transplantation for severe osteogenesis imperfecta

2016-01 to 2020-12 | Grant
European Commission (London, London, GB)
Source: Self-asserted source
Anna David

Stem cell therapy to treat severe osteogenesis imperfecta

2016-01 to 2018-02 | Grant
Swedish Research Council Framework (Stockholm, SE)
Source: Self-asserted source
Anna David

Repair of trachea defects in babies with fetal stem cells and bioactive membrane technology

2016-01 to 2017-12 | Grant
Wellcome Trust (London, London, GB)
Source: Self-asserted source
Anna David

Recruitment of a fetal surgeon and costs to establish a Centre for Prenatal Therapy at UCLH/UCL/GOSH/ ICH

2015-10 to 2020-10 | Grant
Great Ormond Street Hospital Charity (London, London, GB)
Source: Self-asserted source
Anna David

A tissue engineering approach to treat defects in the windpipe of babies with fetal stem cells

2015-09 to 2019-04 | Grant
Rosetrees Trust (London, London, GB)
Source: Self-asserted source
Anna David

Healing the human amniotic membrane in an artificial trauma model

2015-03 to 2016-03 | Grant
Queen Mary, University of London (London, London, GB)
Source: Self-asserted source
Anna David

Human amniotic fluid-derived induced pluripotent stem cells for the treatment of osteogenesis imperfecta

2014-09 to 2017-09 | Grant
Rosetrees Trust Project Grant (Edgware, Middlesex, GB)
Source: Self-asserted source
Anna David

Role of connexin 43: Putative factor which affects fetal membrane healing and tissue strength

2014-09 to 2017-09 | Grant
Rosetrees Trust (London, London, GB)
Source: Self-asserted source
Anna David

Role of connexin 43: Putative factor which affects fetal membrane healing and tissue strength.

2014-09 to 2017-09 | Grant
Rosetrees Trust Project Grant (Edgware, Middlesex, GB)
Source: Self-asserted source
Anna David

Human amniotic fluid-derived induced pluripotent stem cells for the treatment of osteogenesis imperfecta

2014-09 to 2017-08 | Grant
Rosetrees Trust (London, London, GB)
Source: Self-asserted source
Anna David

GIFT-Surg: Image-guided intrauterine minimally invasive fetal diagnosis and therapy

2014-07 to 2021-06 | Grant
Wellcome Trust (London, GB)
Source: Self-asserted source
Anna David

EpiFever: Elucidating the molecular mechanism underlying epidural related maternal fever

2014-07 to 2016-06 | Grant
Obstetric Anaesthetists' Association (London, GB)
Source: Self-asserted source
Anna David

Human amniotic fluid stem cells for treatment of necrotizing enterocolitis in neonates

2014-05 to 2016-04 | Grant
Rosetrees Trust (London, GB)
Source: Self-asserted source
Anna David

To develop and take to market a novel treatment for fetal growth restriction.

2014-03 to 2021-03 | Grant
Private equity (London, GB)
Source: Self-asserted source
Anna David

Investigating long term outcomes following maternal gene therapy for fetal growth restriction

2014-03 to 2016-04 | Grant
Action Medical Research: GN2169 (Horsham, GB)
Source: Self-asserted source
Anna David

Image-guided intrauterine minimally invasive fetal diagnosis and therapy

2014-01 to 2021-01 | Grant
Wellcome Trust and EPSRC (London, GB)
Source: Self-asserted source
Anna David

Start-up industrial investment

2014 to 2017 | Grant
Magnus Growth (London, GB)
Source: Self-asserted source
Anna David

Research Doctor for Preterm Birth research

2013-12 to 2014-12 | Grant
Central and East London CLRN (London, GB)
Source: Self-asserted source
Anna David

Centre for Doctoral Training in Medical Imaging

2013-11 to present | Grant
EPSRC (Swindon, GB)
Source: Self-asserted source
Anna David

Elucidating the molecular mechanism underlying epidural related maternal fever

2013-07 to 2015-07 | Grant
Obstetric Anaesthetists' Association (London, GB)
Source: Self-asserted source
Anna David

Human amniotic fluid stem cells for treatment of necrotizing enterocolitis (NEC) in neonates

2013-06 to present | Grant
Rosetrees Trust (Edgeware, Middlesex, GB)
Source: Self-asserted source
Anna David

Vevo 2100 ultrasound small animal ultrasound machine

2013-03 to present | Grant
UCL School of Life and Medical Sciences Capital Equipment Fund. (London, GB)
Source: Self-asserted source
Anna David

EVERREST - Does vascular endothelial growth factor gene therapy safely improve outcome in severe early-onset fetal growth restriction?

2013-01 to 2019-01 | Grant
European Commission FP7-HEALTH-2012-INNOVATION-1 award, Proposal No: 305823-2 (Brussels, BE)
Source: Self-asserted source
Anna David

Can VEGF gene therapy increase fetal growth?

2012-10 to 2014-04 | Grant
Rosetrees Trust (Edgeware, Middx, GB)
Source: Self-asserted source
Anna David

Countering nutritionally induced intrauterine growth restriction with VEGF gene therapy: Impacts on fetal developmental outcomes

2012-09 to 2014-09 | Grant
National Institute of Food and Agriculture (DC, DC, US)
Source: Self-asserted source
Anna David

Service support costs for “POPPY: Saliva Progesterone as a Predictive Test for Pre-term labour”,

2012-03 to 2013-03 | Grant
Central and East London CLRN Contingency Funding (London, GB)
Source: Self-asserted source
Anna David

An investigation of the role of maternal immune regulation in bacterial accumulation leading to preterm birth”

2011-09 to 2013-08 | Grant
Action Medical Research (Horsham, GB)
Source: Self-asserted source
Anna David

POPPY: Saliva Progesterone as a Predictive Test for Pre-term labour”.

2011-01 to 2013-07 | Grant
National Institute for Health Research (NIHR) Research for Innovation, (London, GB)
Source: Self-asserted source
Anna David

In utero transplantation of autologous amniotic fluid stem cells: preclinical study in a large animal model

2011-01 to 2012-01 | Grant
National Science Council Taiwan (., TW)
Source: Self-asserted source
Anna David

EQUIPP: Evaluation of fetal fibronectin with a quantitative instrument for the prediction of preterm birth”

2010-12 to 2012-07 | Grant
NIHR-CSP (London, GB)
Source: Self-asserted source
Anna David

Influence of proteolysis on collagen organisation within amniotic membrane. Synchrotron Beamtime Proposal for 6 shifts

2010-04 to present | Grant
Science and Technologies Funding Council and Wellcome Trust. (London, GB)
Source: Self-asserted source
Anna David

does progesterone prophylaxis to prevent preterm labour improve outcome? – a randomised double blind placebo controlled trial

2010-04 to 2013-03 | Grant
Central and East London CLRN Contingency Funding (London, GB)
Source: Self-asserted source
Anna David

Establishing a biomedical imaging PhD training scheme

2009-10 to present | Grant
MRC Capacity Building award (London, GB)
Source: Self-asserted source
Anna David

Translational research grant.

2009-10 to present | Grant
UCL/UCLH Comprehensive Biomedical Research Centre (London, GB)
Source: Self-asserted source
Anna David

Human placental studies to support an adenovirus-mediated VEGF gene medicine for the treatment of fetal growth restriction

2009-08 to 2012-09 | Grant
Ark Therapeutics (London, GB)
Source: Self-asserted source
Anna David

In utero transplantation of autologous amniotic fluid stem cells. Preclinical study in a large animal model.

2009-05 to 2011-04 | Grant
BDF Newlife (Cannock, Staffordshire, GB)
Source: Self-asserted source
Anna David

To establish a new molecular imaging facility in CABI.

2009-01 to present | Grant
UCL Capital Infrastructure Fund (CIF) (London, GB)
Source: Self-asserted source
Anna David

Does over-expression of VEGF increase fetal growth?

2008-12 to 2013-11 | Grant
Action Medical Research (Horsham, GB)
Source: Self-asserted source
Anna David

Effects of local VEGF over-expression in fetal growth restricted guinea pigs

2008-12 to 2010-10 | Grant
Ark Therapeutics Plc. (London, GB)
Source: Self-asserted source
Anna David

An investigation of collagen organisation in pre-term ruptured amniotic membanes

2008-04 to present | Grant
Science and Technologies Funding Council and Wellcome Trust. (London, GB)
Source: Self-asserted source
Anna David

Long term effects of local VEGF over-expression in normal pregnant sheep

2007-09 to 2010-08 | Grant
Ark Therapeutics Plc (London, GB)
Source: Self-asserted source
Anna David

Recreational drugs as aetiological factors in fetal malformations

2006-05 to 2010-04 | Grant
BDF Newlife (Cannock, GB)
Source: Self-asserted source
Anna David

Markers of oxidative stress in early pregnancy

2006-02 to 2008-01 | Grant
Mason Medical Research Fund (Edinburgh, GB)
Source: Self-asserted source
Anna David

Peer review (8 reviews for 7 publications/grants)

Review activity for BMC medicine (1)
Review activity for European journal of obstetrics, gynecology, and reproductive biology. (1)
Review activity for Gene therapy. (2)
Review activity for Molecular diagnosis & therapy. (1)
Review activity for Molecular therapy (1)
Review activity for Nature biomedical engineering. (1)
Review activity for Nature medicine. (1)
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