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Scopus Author ID: 24069038100

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Employment (1)

Massachusetts General Hospital: Boston, MA, US

2018-09-01 to present | Physician
Employment
Source: Self-asserted source
Douglas Micalizzi

Education and qualifications (2)

University of Colorado: Denver, CO, US

2003-06-01 to 2012-05-15 | MD, PhD (Molecular Biology)
Education
Source: Self-asserted source
Douglas Micalizzi

Villanova University: Villanova, PA, US

1999-08-01 to 2003-05-15 | BS (Chemistry)
Education
Source: Self-asserted source
Douglas Micalizzi

Professional activities (1)

American Society of Clinical Oncology: Alexandria, VA, US

2014-07-01 to present | Member
Service
Source: Self-asserted source
Douglas Micalizzi

Funding (1)

The Molecular Mechanism of Six1-Induced Tumor Initiation and Progression

2004-10-01 to 2005-09-01 | Grant
Congressionally Directed Medical Research Programs (Frederick, US)
URL: https://app.dimensions.ai/details/grant/grant.7133440
GRANT_NUMBER:

W81XWH-06-1-0757
Source: Self-asserted source
Douglas Micalizzi via DimensionsWizard

Works (22)

A pooled electronic consultation program to improve access to genetics specialists

Genetics in Medicine Open
2023 | Journal article
DOI: 10.1016/j.gimo.2023.100819
Contributors: Emma K. Folkerts; Renée C. Pelletier; Daniel C. Chung; Susan A. Goldstein; Douglas S. Micalizzi; Kristen M. Shannon; David A. Sweetser; Eugene K. Wong; Heidi L. Rehm; Leland E. Hull
Source: check_circle
Crossref

A Pooled Electronic Consultation Program to Improve Access to Genetics Specialists

2023-02-10 | Preprint
DOI: 10.1101/2023.02.08.23284667
Contributors: Emma K. Folkerts; Renée C. Pelletier; Daniel C. Chung; Susan A. Goldstein; Douglas S. Micalizzi; Kristen M. Shannon; David A. Sweetser; Eugene K. Wong; Heidi L. Rehm; Leland E. Hull
Source: check_circle
Crossref

Differential Kinase Activity Across Prostate Tumor Compartments Defines Sensitivity to Target Inhibition

Cancer Research
2022-03-15 | Journal article
DOI: 10.1158/0008-5472.CAN-21-2609
Contributors: Nezihi Murat Karabacak; Yu Zheng; Taronish D. Dubash; Risa Burr; Douglas S. Micalizzi; Ben S. Wittner; Maoxuan Lin; Devon F. Wiley; Valentine Comaills; Erin Emmons et al.
Source: check_circle
Crossref

Translational Regulation of Cancer Metastasis

Cancer Research
2021-02-01 | Journal article
DOI: 10.1158/0008-5472.CAN-20-2720
Contributors: Douglas S. Micalizzi; Richard Y. Ebright; Daniel A. Haber; Shyamala Maheswaran
Source: check_circle
Crossref

A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells

Genome Biology
2020 | Journal article
DOI: 10.1186/s13059-020-1936-4
EID:

2-s2.0-85079108160

Part of ISBN:

1474760X 14747596
Contributors: Lee, S.; Micalizzi, D.; Truesdell, S.S.; Bukhari, S.I.A.; Boukhali, M.; Lombardi-Story, J.; Kato, Y.; Choo, M.-K.; Dey-Guha, I.; Ji, F. et al.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis

Science
2020 | Journal article
DOI: 10.1126/science.aay0939
EID:

2-s2.0-85082498166

Part of ISBN:

10959203 00368075
Contributors: Ebright, R.Y.; Lee, S.; Wittner, B.S.; Niederhoffer, K.L.; Nicholson, B.T.; Bardia, A.; Truesdell, S.; Wiley, D.F.; Wesley, B.; Li, S. et al.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

HIF1A signaling selectively supports proliferation of breast cancer in the brain

Nature Communications
2020-12-09 | Journal article
DOI: 10.1038/s41467-020-20144-w
Contributors: Richard Y. Ebright; Marcus A. Zachariah; Douglas S. Micalizzi; Ben S. Wittner; Kira L. Niederhoffer; Linda T. Nieman; Brian Chirn; Devon F. Wiley; Benjamin Wesley; Brian Shaw et al.
Source: check_circle
Crossref

On the trail of invasive cells in breast cancer

Nature
2018 | Journal article
DOI: 10.1038/d41586-018-01634-w
EID:

2-s2.0-85042151792

Part of ISBN:

14764687 00280836
Contributors: Micalizzi, D.S.; Maheswaran, S.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

A conduit to metastasis: Circulating tumor cell biology

Genes and Development
2017 | Journal article
DOI: 10.1101/gad.305805.117
EID:

2-s2.0-85032374326

Part of ISBN:

15495477 08909369
Contributors: Micalizzi, D.S.; Maheswaran, S.; Haber, D.A.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

Cancer metastasis through the prism of epithelial-to-mesenchymal transition in circulating tumor cells

Molecular Oncology
2017 | Journal article
DOI: 10.1002/1878-0261.12081
EID:

2-s2.0-85021816046

Part of ISBN:

18780261 15747891
Contributors: Micalizzi, D.S.; Haber, D.A.; Maheswaran, S.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

A man in his 40s with headache, lethargy, and altered mental status

JAMA Neurology
2015 | Journal article
DOI: 10.1001/jamaneurol.2015.1375
EID:

2-s2.0-84942284351

Part of ISBN:

21686149
Contributors: McKee, K.E.; Etherton, M.R.; Lovitch, S.B.; Gupta, A.S.; Micalizzi, D.S.; Tierney, T.; Wadleigh, M.; Vaitkevicus, H.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p

Nature Communications
2015 | Journal article
DOI: 10.1038/ncomms10077
EID:

2-s2.0-84951910396

Part of ISBN:

20411723
Contributors: Towers, C.G.; Guarnieri, A.L.; Micalizzi, D.S.; Harrell, J.C.; Gillen, A.E.; Kim, J.; Wang, C.-A.; Oliphant, M.U.J.; Drasin, D.J.; Guney, M.A. et al.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and transforming growth factor-beta signaling pathways

Breast Cancer Research
2012 | Journal article
DOI: 10.1186/bcr3219
EID:

2-s2.0-84863441826

Part of ISBN:

14655411 1465542X
Contributors: Iwanaga, R.; Wang, C.-A.; Micalizzi, D.S.; Harrell, J.C.; Jedlicka, P.; Sartorius, C.A.; Kabos, P.; Farabaugh, S.M.; Bradford, A.P.; Ford, H.L.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-Β signaling, epithelial-mesenchymal transition, and cancer stem cell properties

Oncogene
2012 | Journal article
DOI: 10.1038/onc.2011.259
EID:

2-s2.0-84856536436

Part of ISBN:

09509232 14765594
Contributors: Farabaugh, S.M.; Micalizzi, D.S.; Jedlicka, P.; Zhao, R.; Ford, H.L.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer

Journal of Clinical Investigation
2012 | Journal article
DOI: 10.1172/JCI59858
EID:

2-s2.0-84860172725

Part of ISBN:

00219738 15588238
Contributors: Wang, C.-A.; Jedlicka, P.; Patrick, A.N.; Micalizzi, D.S.; Lemmer, K.C.; Deitsch, E.; Casás-Selves, M.; Harrell, J.C.; Ford, H.L.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer

Oncogene
2012 | Journal article
DOI: 10.1038/onc.2012.11
EID:

2-s2.0-84871246002

Part of ISBN:

09509232 14765594
Contributors: Smith, A.L.; Iwanaga, R.; Drasin, D.J.; Micalizzi, D.S.; Vartuli, R.L.; Tan, A.-C.; Ford, H.L.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

Epithelial-mesenchymal transition in cancer: Parallels between normal development and tumor progression

Journal of Mammary Gland Biology and Neoplasia
2010 | Journal article
DOI: 10.1007/s10911-010-9178-9
EID:

2-s2.0-77954860342

Part of ISBN:

10833021
Contributors: Micalizzi, D.S.; Farabaugh, S.M.; Ford, H.L.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

Homeoprotein Six1 increases TGF-β type I receptor and converts TGF-β signaling from suppressive to supportive for tumor growth

Cancer Research
2010 | Journal article
DOI: 10.1158/0008-5472.CAN-10-1354
EID:

2-s2.0-78650359160

Part of ISBN:

00085472 15387445
Contributors: Micalizzi, D.S.; Wang, C.-A.; Farabaugh, S.M.; Schiemann, W.P.; Ford, H.L.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

Epithelial-mesenchymal transition in development and cancer

Future Oncology
2009 | Journal article
DOI: 10.2217/fon.09.94
EID:

2-s2.0-75649086115

Part of ISBN:

14796694 17448301
Contributors: Micalizzi, D.S.; Ford, H.L.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-β signaling

Journal of Clinical Investigation
2009 | Journal article
DOI: 10.1172/JCI37815
EID:

2-s2.0-70349213381

Part of ISBN:

00219738 15588238
Contributors: Micalizzi, D.S.; Christensen, K.L.; Jedlicka, P.; Coletta, R.D.; Barón, A.E.; Harrell, J.C.; Horwitz, K.B.; Billheimer, D.; Heichman, K.A.; Welm, A.L. et al.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

Six1 overexpression in mammary cells induces genomic instability and is sufficient for malignant transformation

Cancer Research
2008 | Journal article
DOI: 10.1158/0008-5472.CAN-07-3141
EID:

2-s2.0-42049120053

Part of ISBN:

00085472
Contributors: Coletta, R.D.; Christensen, K.L.; Micalizzi, D.S.; Jedlicka, P.; Varella-Garcia, M.; Ford, H.L.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier

Synthesis of the polyketomycin disaccharide

Tetrahedron Asymmetry
2003 | Journal article
DOI: 10.1016/j.tetasy.2003.07.023
EID:

2-s2.0-1642359191

Part of ISBN:

09574166
Contributors: Micalizzi, D.S.; Dougherty, J.P.; Noecker, L.A.; Smith, G.R.; Giuliano, R.M.
Source: Self-asserted source
Douglas Micalizzi via Scopus - Elsevier
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