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Loop profile: 2047450

Keywords

Oganoids, Emerging infectious diseases, Broadly neutrilization antibodies

Countries

China, Hong Kong SAR China

Activities

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Employment (1)

Fudan University: Shanghai, CN

(Institute of Infection and Health)
Employment
Source: Self-asserted source
Xiaoyu Zhao

Works (39)

Decoding broadly neutralizing antibodies: a milestone in SFTSV therapy

eBioMedicine
2025-01 | Journal article
DOI: 10.1016/j.ebiom.2024.105527
Contributors: Xiaoyu Zhao; Hin Chu
Source: check_circle
Crossref

Bispecific antibodies provide broad neutralization of emerging beta-coronaviruses by targeting ACE2 and viral spikes

Emerging Microbes & Infections
2024-12-31 | Journal article
DOI: 10.1080/22221751.2024.2404166
Part of ISSN: 2222-1751
Contributors: Minghui Li; Chaoyue Zhao; Jialu Shi; Xun Wang; Yuanchen Liu; Xiaoyu Zhao; Guonan Cai; Hin Chu; Pengfei Wang
Source: Self-asserted source
Xiaoyu Zhao

Vascular endothelial growth factor receptor 2 as a potential host target for the inhibition of enterovirus replication

Journal of Virology
2024-10-22 | Journal article
DOI: 10.1128/jvi.01129-24
Contributors: Xiaoyu Zhao; Rui Qiao; Meng Hao; Longfa Xu; Dong Wang; Yinying Lu; Jiayan Li; Jing Wu; Yi Li; Tong Cheng et al.
Source: check_circle
Crossref

Lineage-specific pathogenicity, immune evasion, and virological features of SARS-CoV-2 BA.2.86/JN.1 and EG.5.1/HK.3

Nature Communications
2024-10-09 | Journal article
DOI: 10.1038/s41467-024-53033-7
Contributors: Yuanchen Liu; Xiaoyu Zhao; Jialu Shi; Yajie Wang; Huan Liu; Ye-Fan Hu; Bingjie Hu; Huiping Shuai; Terrence Tsz-Tai Yuen; Yue Chai et al.
Source: check_circle
Crossref

Broad‐spectrum coronavirus neutralization induced by hetero RBD‐Fc protein vaccine

Journal of Medical Virology
2024-09 | Journal article
DOI: 10.1002/jmv.29917
Part of ISSN: 0146-6615
Part of ISSN: 1096-9071
Contributors: chaoyue jaul; Guonan Cai; Shuai Jiang; Xun Wang; Chen Li; Xinyu Liu; Rui Qiao; Xiaoyu Zhao; Yuchen Cui; Yanjia Chen et al.
Source: Self-asserted source
Xiaoyu Zhao

Longitudinal Analysis of Humoral and Cellular Immune Response up to 6 Months after SARS-CoV-2 BA.5/BF.7/XBB Breakthrough Infection and BA.5/BF.7-XBB Reinfection

Vaccines
2024-04 | Journal article | Author
DOI: 10.3390/vaccines12050464
Contributors: Xun Wang; Meng Zhang; Kaifeng Wei; Chen Li; Jinghui Yang; Shujun Jiang; Chaoyue Zhao; Xiaoyu Zhao; Rui Qiao; Yuchen Cui et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination

Cell Discovery
2024-02-06 | Journal article
DOI: 10.1038/s41421-024-00648-1
Contributors: Xiaoyu Zhao; Tianyi Qiu; Xiner Huang; Qiyu Mao; Yajie Wang; Rui Qiao; Jiayan Li; Tiantian Mao; Yuan Wang; Yewei Cun et al.
Source: check_circle
Crossref

Enhanced neutralization of SARS-CoV-2 variant BA.2.86 and XBB sub-lineages by a tetravalent COVID-19 vaccine booster

Cell Host & Microbe
2024-01 | Journal article
DOI: 10.1016/j.chom.2023.11.012
Part of ISSN: 1931-3128
Contributors: Xun Wang; Shujun Jiang; Wentai Ma; Xiangnan Li; Kaifeng Wei; Faren Xie; Chaoyue Zhao; Xiaoyu Zhao; Shidi Wang; Chen Li et al.
Source: Self-asserted source
Xiaoyu Zhao

Structure-based virtual screening of ROCK1 inhibitors for the discovery of Enterovirus-A71 antivirals

Virology
2023-08 | Journal article | Author
DOI: 10.1016/j.virol.2023.06.011
Part of ISSN: 0042-6822
Contributors: Rui Qiao; Wanggang Tang; Jiayan Li; Chen Li; Chaoyue Zhao; Xun Wang; Minghui Li; Yuchen Cui; Yanjia Chen; Guonan Cai et al.
Source: Self-asserted source
Xiaoyu Zhao

In Vitro Antibody-Dependent Enhancement of SARS-CoV-2 Infection Could Be Abolished by Adding Human IgG

Pathogens
2023-08-30 | Journal article
DOI: 10.3390/pathogens12091108
Part of ISSN: 2076-0817
Contributors: Xun Wang; Minghui Li; Panpan Lu; Chen Li; Chaoyue Zhao; Xiaoyu Zhao; Rui Qiao; Yuchen Cui; Yanjia Chen; Jiayan Li et al.
Source: Self-asserted source
Xiaoyu Zhao

Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses

Nature Reviews Immunology
2023-03 | Journal article
DOI: 10.1038/s41577-022-00784-3
Part of ISSN: 1474-1733
Part of ISSN: 1474-1741
Contributors: Yanjia Chen; Xiaoyu Zhao; Hao Zhou; Huanzhang Zhu; Jiang Shibo; Pengfei Wang
Source: Self-asserted source
Xiaoyu Zhao

Limited enhancement of antibody and B‐cell responses to prototype booster vaccination following SARS‐CoV‐2 Delta breakthrough infection

Journal of Medical Virology
2023-02 | Journal article
DOI: 10.1002/jmv.28540
Part of ISSN: 0146-6615
Part of ISSN: 1096-9071
Contributors: Xun Wang; Xing He; Shujun Jiang; Zhangfan Fu; Shuai Jiang; Xiaoyu Zhao; Chaoyue Zhao; Yaning Li; Dianfan Li; Wenhong Zhang et al.
Source: Self-asserted source
Xiaoyu Zhao

Homologous or heterologous booster of inactivated vaccine reduces SARS-CoV-2 Omicron variant escape from neutralizing antibodies

Emerging Microbes & Infections
2022-12-31 | Journal article
DOI: 10.1080/22221751.2022.2030200
Part of ISSN: 2222-1751
Source: Self-asserted source
Xiaoyu Zhao

Neutralization of Omicron BA.4/BA.5 and BA.2.75 by booster vaccination or BA.2 breakthrough infection sera

Cell Discovery
2022-10-13 | Journal article
DOI: 10.1038/s41421-022-00472-5
Part of ISSN: 2056-5968
Contributors: Xun Wang; Jingwen Ai; Xiangnan Li; Xiaoyu Zhao; Jing Wu; Haocheng Zhang; Xing He; Chaoyue Zhao; Rui Qiao; Minghui Li et al.
Source: Self-asserted source
Xiaoyu Zhao

Coronaviruses exploit a host cysteine-aspartic protease for replication

Nature
2022-08-03 | Journal article | Author
DOI: 10.1038/s41586-022-05148-4
Part of ISSN: 0028-0836
Part of ISSN: 1476-4687
Contributors: HIN CHU; Yuxin Hou; Dong Yang; Lei Wen; Shuai H.; Chaemin Yoon; Jialu Shi; Yue Chai; Terrence Tsz-Tai Yuen; Bingjie Hu et al.
Source: Self-asserted source
Xiaoyu Zhao

Neutralization of distinct Omicron sublineages by longitudinal vaccination sera.

Journal of medical virology
2022-07-30 | Journal article
DOI: 10.1002/jmv.28017
PMID: 35869360
Contributors: Wang X; Zhao X; Cui Y; Qiao R; Li M; Chen Y; Yang L; Jiang Shibo; Wang P
Source: Self-asserted source
Xiaoyu Zhao

Rock1 is a novel host dependency factor of human enterovirus A71: Implication as a drug target

Journal of Medical Virology
2022-07-13 | Journal article
DOI: 10.1002/jmv.27975
Part of ISSN: 0146-6615
Part of ISSN: 1096-9071
Source: Self-asserted source
Xiaoyu Zhao

Antibody evasion of SARS-CoV-2 Omicron BA.1, BA.1.1, BA.2, and BA.3 sub-lineages

Cell Host & Microbe
2022-05 | Journal article
DOI: 10.1016/j.chom.2022.05.001
Part of ISSN: 1931-3128
Source: Self-asserted source
Xiaoyu Zhao

SPINK6 inhibits human airway serine proteases and restricts influenza virus activation

EMBO Molecular Medicine
2022-01-11 | Journal article
DOI: 10.15252/emmm.202114485
Part of ISSN: 1757-4676
Part of ISSN: 1757-4684
Source: Self-asserted source
Xiaoyu Zhao

Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity

Science Advances
2021-06-18 | Journal article
DOI: 10.1126/sciadv.abf8577
Part of ISSN: 2375-2548
Source: Self-asserted source
Xiaoyu Zhao

Human Intestinal Organoids Recapitulate Enteric Infections of Enterovirus and Coronavirus

Stem Cell Reports
2021-03 | Journal article
DOI: 10.1016/j.stemcr.2021.02.009
Part of ISSN: 2213-6711
Source: Self-asserted source
Xiaoyu Zhao

Development of Three-Dimensional Human Intestinal Organoids as a Physiologically Relevant Model for Characterizing the Viral Replication Kinetics and Antiviral Susceptibility of Enteroviruses

Biomedicines
2021-01-18 | Journal article
DOI: 10.3390/biomedicines9010088
Part of ISSN: 2227-9059
Source: Self-asserted source
Xiaoyu Zhao

STAT2-dependent restriction of Zika virus by human macrophages but not dendritic cells

Emerging Microbes & Infections
2021-01-01 | Journal article
DOI: 10.1080/22221751.2021.1929503
Part of ISSN: 2222-1751
Source: Self-asserted source
Xiaoyu Zhao

Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target

Science Advances
2020-08-28 | Journal article
DOI: 10.1126/sciadv.aba7910
Part of ISSN: 2375-2548
Source: Self-asserted source
Xiaoyu Zhao
grade
Preferred source (of 2)‎

Infection of bat and human intestinal organoids by SARS-CoV-2

Nature Medicine
2020-07 | Journal article
DOI: 10.1038/s41591-020-0912-6
Part of ISSN: 1078-8956
Part of ISSN: 1546-170X
Source: Self-asserted source
Xiaoyu Zhao
grade
Preferred source (of 2)‎

Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target

Emerging Microbes & Infections
2020-01-01 | Journal article
DOI: 10.1080/22221751.2020.1850183
Part of ISSN: 2222-1751
Source: Self-asserted source
Xiaoyu Zhao

SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target

Nature Communications
2019-12 | Journal article
DOI: 10.1038/s41467-018-08015-x
Part of ISSN: 2041-1723
Source: Self-asserted source
Xiaoyu Zhao

Activation of C-Type Lectin Receptor and (RIG)-I-Like Receptors Contributes to Proinflammatory Response in Middle East Respiratory Syndrome Coronavirus-Infected Macrophages

The Journal of Infectious Diseases
2019-09-28 | Journal article
DOI: 10.1093/infdis/jiz483
Part of ISSN: 0022-1899
Part of ISSN: 1537-6613
Source: Self-asserted source
Xiaoyu Zhao

Establishment of a lethal aged mouse model of human respiratory syncytial virus infection

Antiviral Research
2019-01 | Journal article
DOI: 10.1016/j.antiviral.2018.11.015
Part of ISSN: 0166-3542
Source: Self-asserted source
Xiaoyu Zhao
grade
Preferred source (of 2)‎

Identification and characterization of <scp>GLDC</scp> as host susceptibility gene to severe influenza

EMBO Molecular Medicine
2019-01 | Journal article
DOI: 10.15252/emmm.201809528
Part of ISSN: 1757-4676
Part of ISSN: 1757-4684
Source: Self-asserted source
Xiaoyu Zhao
grade
Preferred source (of 2)‎

Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza

Nature Communications
2018-12 | Journal article
DOI: 10.1038/s41467-018-04792-7
Part of ISSN: 2041-1723
Source: Self-asserted source
Xiaoyu Zhao

Large-scale sequence analysis reveals novel human-adaptive markers in PB2 segment of seasonal influenza A viruses

Emerging Microbes &amp; Infections
2018-12-01 | Journal article
DOI: 10.1038/s41426-018-0050-0
Part of ISSN: 2222-1751
Source: Self-asserted source
Xiaoyu Zhao

Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells

Journal of Biological Chemistry
2018-07 | Journal article
DOI: 10.1074/jbc.ra118.001897
Part of ISSN: 0021-9258
Source: Self-asserted source
Xiaoyu Zhao

Differentiated human airway organoids to assess infectivity of emerging influenza virus

Proceedings of the National Academy of Sciences
2018-06-26 | Journal article
DOI: 10.1073/pnas.1806308115
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Xiaoyu Zhao

Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus

Science Advances
2017-11-03 | Journal article
DOI: 10.1126/sciadv.aao4966
Part of ISSN: 2375-2548
Source: Self-asserted source
Xiaoyu Zhao
grade
Preferred source (of 2)‎

Novel residues in the PA protein of avian influenza H7N7 virus affect virulence in mammalian hosts

Virology
2016-11 | Journal article
DOI: 10.1016/j.virol.2016.08.004
Part of ISSN: 0042-6822
Source: Self-asserted source
Xiaoyu Zhao

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 Is an Important Surface Attachment Factor That Facilitates Entry of Middle East Respiratory Syndrome Coronavirus

Journal of Virology
2016-10-15 | Journal article
DOI: 10.1128/jvi.01133-16
Part of ISSN: 0022-538X
Part of ISSN: 1098-5514
Source: Self-asserted source
Xiaoyu Zhao
grade
Preferred source (of 9)‎

Enzymatic Characterization of a Type II Isocitrate Dehydrogenase from Pathogenic Leptospira interrogans serovar Lai Strain 56601

Applied Biochemistry and Biotechnology
2014-01 | Journal article
DOI: 10.1007/s12010-013-0521-7
Part of ISSN: 0273-2289
Part of ISSN: 1559-0291
Source: Self-asserted source
Xiaoyu Zhao

Biochemical characterization of NADP+-dependent isocitrate dehydrogenase from Microcystis aeruginosa PCC7806

Molecular Biology Reports
2013-04 | Journal article
DOI: 10.1007/s11033-012-2371-8
Part of ISSN: 0301-4851
Part of ISSN: 1573-4978
Source: Self-asserted source
Xiaoyu Zhao

Peer review (6 reviews for 3 publications/grants)

Review activity for Vaccines. (3)
Review activity for Virus research (1)
Review activity for Viruses. (2)
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