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Immunopathology Group_Biocruces Bizkaia

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Scopus Author ID: 56281502000

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Employment (2)

Universidad del País Vasco/Euskal Herriko Unibertsitatea: Leioa, Bizkaia, ES

2024-09-01 to present | Profesor Ayudante Doctors (Departamento de Gnética, Antropología Física y Fisiología Animal)
Employment
Source: Self-asserted source
Olatz Zenarruzabeitia

Biobizkaia Bizkaia Health Research Intitute: Barakaldo, ES

2014-03-17 to present | PhD (Immunopathology Group)
Employment
Source: Self-asserted source
Olatz Zenarruzabeitia

Education and qualifications (3)

Universidad del País Vasco/Euskal Herriko Unibertsitatea: Leioa, Bizkaia, ES

2008 to 2012-04-27 | PhD Biology (Genética, Antropología Física y Fisiología Animal)
Education
Source: Self-asserted source
Olatz Zenarruzabeitia

Universidad del País Vasco - Campus Bizkaia: Leioa, País Vasco, ES

2007-09 to 2008-06 | Master en Biología Molecular y Biomedicina
Education
Source: Self-asserted source
Olatz Zenarruzabeitia

Universitat Autònoma de Barcelona: Barcelona, ES

2002-09 to 2007-06 | Licenciado en Biología
Education
Source: Self-asserted source
Olatz Zenarruzabeitia

Works (29)

CD151 identifies an NK cell subset that is enriched in COVID-19 patients and correlates with disease severity

Journal of Infection
2024-12 | Journal article
DOI: 10.1016/j.jinf.2024.106304
Contributors: Ainhoa Amarilla-Irusta; Olatz Zenarruzabeitia; Arrate Sevilla; Víctor Sandá; Ainara Lopez-Pardo; Gabirel Astarloa-Pando; Raquel Pérez-Garay; Silvia Pérez-Fernández; Susana Meijide; Natale Imaz-Ayo et al.
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E2f2 Attenuates Apoptosis of Activated T Lymphocytes and Protects from Immune-Mediated Injury through Repression of Fas and FasL

International Journal of Molecular Sciences
2021-12-28 | Journal article
DOI: 10.3390/ijms23010311
Contributors: Noor Mustafa; Jone Mitxelena; Arantza Infante; Olatz Zenarruzabeitia; Ainhoa Eriz; Ainhoa Iglesias-Ara; Ana M. Zubiaga
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PIPE‐cloned human IgE and IgG4 antibodies: New tools for investigating cow's milk allergy and tolerance

Allergy
2021-05 | Journal article
DOI: 10.1111/all.14604
Contributors: Christina L. Pranger; Judit Fazekas‐Singer; Verena K. Köhler; Isabella Pali‐Schöll; Alessandro Fiocchi; Sophia N. Karagiannis; Olatz Zenarruzabeitia; Francisco Borrego; Erika Jensen‐Jarolim
Source: check_circle
Crossref

Human NK Cells in Autologous Hematopoietic Stem Cell Transplantation for Cancer Treatment

Cancers
2021-03-30 | Journal article
DOI: 10.3390/cancers13071589
Contributors: Ane Orrantia; Iñigo Terrén; Gabirel Astarloa-Pando; Olatz Zenarruzabeitia; Francisco Borrego
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Identification and Functional Analysis of Human CD56neg NK Cells by Flow Cytometry

STAR Protocols
2020-12 | Journal article
DOI: 10.1016/j.xpro.2020.100149
Contributors: Ane Orrantia; Iñigo Terrén; Joana Vitallé; Gabirel Astarloa-Pando; Olatz Zenarruzabeitia; Francisco Borrego
Source: check_circle
Crossref

T cell activation, highly armed cytotoxic cells and a sharp shift in monocytes CD300 receptors expression is characteristic of patients with severe COVID-19

2020-12-22 | Preprint
DOI: 10.1101/2020.12.22.423917
Contributors: Olatz Zenarruzabeitia; Gabirel Astarloa-Pando; Iñigo Terrén; Ane Orrantia; Raquel Pérez-Garay; Iratxe Seijas-Betolaza; Javier Nieto-Arana; Natale Imaz-Ayo; Silvia Pérez-Fernández; Eunate Arana-Arri et al.
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Crossref

Modulating NK cell metabolism for cancer immunotherapy

Seminars in Hematology
2020-10 | Journal article
DOI: 10.1053/j.seminhematol.2020.10.003
Contributors: Iñigo Terrén; Ane Orrantia; Joana Vitallé; Gabirel Astarloa-Pando; Olatz Zenarruzabeitia; Francisco Borrego
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Crossref

Human cytokine-induced memory-like NK cells preserve increased glycolysis but the glycolytic-dependence of their effector functions differ between stimuli

2020-08-20 | Preprint
DOI: 10.1101/2020.08.20.258731
Contributors: Iñigo Terrén; Ane Orrantia; Alba Mosteiro; Joana Vitallé; Olatz Zenarruzabeitia; Francisco Borrego
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Crossref

The Expression and Function of CD300 Molecules in the Main Players of Allergic Responses: Mast Cells, Basophils and Eosinophils

International Journal of Molecular Sciences
2020-04-30 | Journal article
DOI: 10.3390/ijms21093173
Contributors: Joana Vitallé; Iñigo Terrén; Ane Orrantia; Agurtzane Bilbao; Pedro M. Gamboa; Francisco Borrego; Olatz Zenarruzabeitia
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NK Cell-Based Immunotherapy in Renal Cell Carcinoma

Cancers
2020-01-29 | Journal article
DOI: 10.3390/cancers12020316
Contributors: Iñigo Terrén; Ane Orrantia; Idoia Mikelez-Alonso; Joana Vitallé; Olatz Zenarruzabeitia; Francisco Borrego
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CD300 receptor family in viral infections

European Journal of Immunology
2019 | Journal article
DOI: 10.1002/eji.201847951
EID:

2-s2.0-85058419769
Contributors: Vitallé, J.; Terrén, I.; Orrantia, A.; Zenarruzabeitia, O.; Borrego, F.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

CD300a inhibits CD16-mediated NK cell effector functions in HIV-1-infected patients

Cellular and Molecular Immunology
2019 | Journal article
DOI: 10.1038/s41423-019-0275-4
EID:

2-s2.0-85071605696
Contributors: Vitallé, J.; Terrén, I.; Orrantia, A.; Pérez-Garay, R.; Vidal, F.; Iribarren, J.A.; Rodríguez, C.; Lirola, A.M.L.; Bernal, E.; Zenarruzabeitia, O. et al.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

CD300c costimulates IgE-mediated basophil activation, and its expression is increased in patients with cow's milk allergy

Journal of Allergy and Clinical Immunology
2019 | Journal article
DOI: 10.1016/j.jaci.2018.05.022
EID:

2-s2.0-85049342782
Contributors: Zenarruzabeitia, O.; Vitallé, J.; Terrén, I.; Orrantia, A.; Astigarraga, I.; Dopazo, L.; Gonzalez, C.; Santos-Díez, L.; Tutau, C.; Gamboa, P.M. et al.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

CFSE dilution to study human T and NK cell proliferation in vitro

Methods in Enzymology
2019 | Book chapter
DOI: 10.1016/bs.mie.2019.05.020
EID:

2-s2.0-85066266032
Contributors: Terrén, I.; Orrantia, A.; Vitallé, J.; Zenarruzabeitia, O.; Borrego, F.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

NK cell metabolism and tumor microenvironment

Frontiers in Immunology
2019 | Journal article
DOI: 10.3389/fimmu.2019.02278
EID:

2-s2.0-85073146487
Contributors: Terrén, I.; Orrantia, A.; Vitallé, J.; Zenarruzabeitia, O.; Borrego, F.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

Increased expression levels of CD300c on basophils from allergic individuals

World Allergy Organization Journal
2019-09 | Journal article
DOI: 10.1016/j.waojou.2019.100060
Contributors: Joana Vitallé; Iñigo Terrén; Ane Orrantia; Aritza Segurola; Yolanda Seras; Pedro M. Gamboa; Francisco Borrego; Olatz Zenarruzabeitia
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Altered expression of CD300a inhibitory receptor on CD4+ T cells from human immunodeficiency virus-1-infected patients: Association with disease progression markers

Frontiers in Immunology
2018 | Journal article
DOI: 10.3389/fimmu.2018.01709
EID:

2-s2.0-85050354080
Contributors: Vitallé, J.; Terrén, I.; Gamboa-Urquijo, L.; Orrantia, A.; Tarancón-Díez, L.; Genebat, M.; Ruiz-Mateos, E.; Leal, M.; García-Obregón, S.; Zenarruzabeitia, O. et al.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

Implication of interleukin-12/15/18 and ruxolitinib in the phenotype, proliferation, and polyfunctionality of human cytokine-preactivated natural killer cells

Frontiers in Immunology
2018 | Journal article
DOI: 10.3389/fimmu.2018.00737
EID:

2-s2.0-85045525156
Contributors: Terrén, I.; Mikelez, I.; Odriozola, I.; Gredilla, A.; González, J.; Orrantia, A.; Vitallé, J.; Zenarruzabeitia, O.; Borrego, F.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

Monocytes phenotype and cytokine production in human immunodeficiency virus-1 infected patients receiving a modified vaccinia ankara-based HIV-1 vaccine: Relationship to CD300 molecules expression

Frontiers in Immunology
2017 | Journal article
DOI: 10.3389/fimmu.2017.00836
EID:

2-s2.0-85025622072
Contributors: Vitallé, J.; Zenarruzabeitia, O.; Terrén, I.; Plana, M.; Guardo, A.C.; Leal, L.; Peña, J.; García, F.; Borrego, F.; Mothe, B. et al.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

Natural killer cells to the attack: Combination therapy against neuroblastoma

Clinical Cancer Research
2017 | Journal article
DOI: 10.1158/1078-0432.CCR-16-2478
EID:

2-s2.0-85012266393
Contributors: Zenarruzabeitia, O.; Vitallé, J.; Astigarraga, I.; Borrego, F.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

CD300c is uniquely expressed on CD56<sup>bright</sup> Natural Killer Cells and differs from CD300a upon ligand recognition

Scientific Reports
2016 | Journal article
DOI: 10.1038/srep23942
EID:

2-s2.0-84962424975
Contributors: Dimitrova, M.; Zenarruzabeitia, O.; Borrego, F.; Simhadri, V.R.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

The expression and function of human CD300 receptors on blood circulating mononuclear cells are distinct in neonates and adults

Scientific Reports
2016 | Journal article
DOI: 10.1038/srep32693
EID:

2-s2.0-84986213303
Contributors: Zenarruzabeitia, O.; Vitallé, J.; García-Obregón, S.; Astigarraga, I.; Eguizabal, C.; Santos, S.; Simhadri, V.R.; Borrego, F.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

A human anti-M2 antibody mediates antibody-dependent cell-mediated cytotoxicity (ADCC) and cytokine secretion by resting and cytokine-preactivated natural killer (NK) cells

PLoS ONE
2015 | Journal article
DOI: 10.1371/journal.pone.0124677
EID:

2-s2.0-84928568864
Contributors: Simhadri, V.R.; Dimitrova, M.; Mariano, J.L.; Zenarruzabeitia, O.; Zhong, W.; Ozawa, T.; Muraguchi, A.; Kishi, H.; Eichelberger, M.C.; Borrego, F.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

E2F1 and E2F2 prevent replicative stress and subsequent p53-dependent organ involution

Cell Death and Differentiation
2015 | Journal article
DOI: 10.1038/cdd.2015.4
EID:

2-s2.0-84941174864
Contributors: Iglesias-Ara, A.; Zenarruzabeitia, O.; Buelta, L.; Merino, J.; Zubiaga, A.M.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

The biology and disease relevance of CD300a, an inhibitory receptor for phosphatidylserine and phosphatidylethanolamine

Journal of Immunology
2015 | Journal article
DOI: 10.4049/jimmunol.1500304
EID:

2-s2.0-84929650331
Contributors: Zenarruzabeitia, O.; Vitallé, J.; Eguizabal, C.; Simhadri, V.R.; Borrego, F.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

Intact IL-12 signaling is necessary for the generation of human natural killer cells with enhanced effector function after restimulation

Journal of Allergy and Clinical Immunology
2014 | Journal article
DOI: 10.1016/j.jaci.2014.06.006
EID:

2-s2.0-84914166384
Contributors: Simhadri, V.R.; Mariano, J.L.; Zenarruzabeitia, O.; Seroogy, C.M.; Holland, S.M.; Kuehn, H.S.; Rosenzweig, S.D.; Borrego, F.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

Involvement of platelet-tumor cell interaction in immune evasion. Potential role of podocalyxin-like protein 1

Frontiers in Oncology
2014 | Journal article
DOI: 10.3389/fonc.2014.00245
EID:

2-s2.0-84907939127
Contributors: Amo, L.; Tamayo-Orbegozo, E.; Maruri, N.; Eguizabal, C.; Zenarruzabeitia, O.; Riñón, M.; Arrieta, A.; Santos, S.; Monge, J.; Vesga, M.A. et al.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

Natural killer cells for cancer immunotherapy: Pluripotent stem cells-derived NK cells as an immunotherapeutic perspective

Frontiers in Immunology
2014 | Journal article
DOI: 10.3389/fimmu.2014.00439
EID:

2-s2.0-84919431238
Contributors: Eguizabal, C.; Zenarruzabeitia, O.; Monge, J.; Santos, S.; Vesga, M.A.; Maruri, N.; Arrieta, A.; Riñón, M.; Tamayo-Orbegozo, E.; Amo, L. et al.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

Accelerated DNA replication in E2F1- and E2F2-deficient macrophages leads to induction of the DNA damage response and p21 CIP1-dependent senescence

Oncogene
2010 | Journal article
DOI: 10.1038/onc.2010.296
EID:

2-s2.0-77958014513
Contributors: Iglesias-Ara, A.; Zenarruzabeitia, O.; Fernandez-Rueda, J.; Sánchez-Tilló, E.; Field, S.J.; Celada, A.; Zubiaga, A.M.
Source: Self-asserted source
Olatz Zenarruzabeitia via Scopus - Elsevier

Peer review (19 reviews for 8 publications/grants)

Review activity for Allergy. (5)
Review activity for Biomedicines. (2)
Review activity for Biomolecules. (1)
Review activity for Cells. (4)
Review activity for Diagnostics. (1)
Review activity for International journal of molecular sciences. (1)
Review activity for International journal of molecular sciences. (4)
Review activity for Medicina. (1)
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