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Polyomics Staff Page

Keywords

Metabolomics, Bioinformatics, Proteomics, Chromatography, Mass Spectrometry

Countries

United Kingdom

Activities

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Employment (3)

University of Edinburgh: Edinburgh, Scotland, GB

2019-01-15 to present | Professor of Biological Mass Spectrometry (Institute of Quantitative Biology, Biochemistry and Biotechnology)
Employment
Source: Self-asserted source
Karl Burgess

University of Glasgow: Glasgow, Glasgow, GB

2009-04-01 to 2019-01-15 | Head of Metabolomics (Glasgow Polyomics)
Employment
Source: Self-asserted source
Karl Burgess

University of Glasgow: Glasgow, Glasgow, GB

2008-04-01 to 2009-03-31 | Post-doc in Proteomics (Sir Henry Wellcome Functional Genomics Facility)
Employment
Source: Self-asserted source
Karl Burgess

Education and qualifications (4)

University of Glasgow: Glasgow, Glasgow, GB

2005-04-01 to 2008-03-31 | PhD in Proteomics (Sir Henry Wellcome Functional Genomics Facility)
Education
Source: Self-asserted source
Karl Burgess

University of Glasgow: Glasgow, Glasgow, GB

2004-10-01 to 2005-09-01 | MRes Biochemistry and Life Sciences (Faculty of Biological and Life Sciences)
Education
Source: Self-asserted source
Karl Burgess

Birkbeck University of London: London, London, GB

1998-10-01 to 2000-07-01 | Molecular Modelling and Bioinformatics (Crystallography)
Education
Source: Self-asserted source
Karl Burgess

University of Reading: Reading, GB

1994-10-01 to 1998-07-01 | Pathobiology (Animal/Microbial Sciences)
Education
Source: Self-asserted source
Karl Burgess

Professional activities (5)

University of Glasgow: Glasgow, Scotland, GB

2019-01-15 to present | Honorary Senior Lecturer (Institute of Infection, Immunity and Inflammation)
Invited position
Source: Self-asserted source
Karl Burgess

Metabolite Profiling Forum: Liverpool, GB

2018-12-03 to present | Director
Membership
Source: Self-asserted source
Karl Burgess

Metabolomics Society: Edinburgh, GB

2015-07-09 to present | Member
Membership
Source: Self-asserted source
Karl Burgess

Scottish Metabolomics Network: Edinburgh, GB

2015-07-05 to present | Founder
Membership
Source: Self-asserted source
Karl Burgess

British Society for Proteome Research: Nottingham, GB

2014-10-05 to 2017-05-03 | Director
Membership
Source: Self-asserted source
Karl Burgess

Funding (5)

Nanopatterned Human Liver BioChips for Drug Hepatotoxicity Screening

2014-07-31 to 2016-07-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/L023571/1
GRANT_NUMBER: BB/L023571/1
Source: Self-asserted source
Karl Burgess via DimensionsWizard

Integron and omics based acceleratation of industrial strain development

2013-11-01 to 2015-10-31 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/K011499/2
GRANT_NUMBER: BB/K011499/2
Source: Self-asserted source
Karl Burgess via DimensionsWizard

Development of nanopatterned substrates for the delivery of high quality stem cells

2013-08-30 to 2016-08-29 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/K011235/1
GRANT_NUMBER: BB/K011235/1
Source: Self-asserted source
Karl Burgess via DimensionsWizard

Multiscale topographical modulation of cells and bacteria for next generation orthopaedic implants.

2013-08-14 to 2016-08-13 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: EP/K034898/1
GRANT_NUMBER: EP/K034898/1
Source: Self-asserted source
Karl Burgess via DimensionsWizard

Integron and omics based acceleratation of industrial strain development

2012-11-01 to 2013-10-31 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/K011499/1
GRANT_NUMBER: BB/K011499/1
Source: Self-asserted source
Karl Burgess via DimensionsWizard

Works (50 of 103)

Items per page:
Page 1 of 3

Optimisation of surfactin yield in Bacillus using data-efficient active learning and high-throughput mass spectrometry

Computational and Structural Biotechnology Journal
2024-12 | Journal article
DOI: 10.1016/j.csbj.2024.02.012
Contributors: Ricardo Valencia Albornoz; Diego Oyarzún; Karl Burgess
Source: check_circle
Crossref

Nanotopography Influences Host–Pathogen Quorum Sensing and Facilitates Selection of Bioactive Metabolites in Mesenchymal Stromal Cells and Pseudomonas aeruginosa Co-Cultures

ACS Applied Materials & Interfaces
2024-08-21 | Journal article
DOI: 10.1021/acsami.4c09291
Contributors: Rosalia Cuahtecontzi Delint; Mohd I. Ishak; Penelope M. Tsimbouri; Vineetha Jayawarna; Karl V. E. Burgess; Gordon Ramage; Angela H. Nobbs; Laila Damiati; Manuel Salmeron-Sanchez; Bo Su et al.
Source: check_circle
Crossref

On‐line targeted metabolomics for real‐time monitoring of relevant compounds in fermentation processes

Biotechnology and Bioengineering
2024-02 | Journal article
DOI: 10.1002/bit.28599
Contributors: Joan Cortada‐Garcia; Jennifer Haggarty; Stefan Weidt; Rónán Daly; S. Alison Arnold; Karl Burgess
Source: check_circle
Crossref

Optimisation of surfactin yield inBacillususing active learning and high-throughput mass spectrometry

2024-01-25 | Preprint
DOI: 10.1101/2024.01.24.576661
Contributors: Ricardo Valencia Albornoz; Diego Oyarzún; Karl Burgess
Source: check_circle
Crossref

On-line targeted metabolomics for real-time monitoring of relevant compounds in fermentation processes

2023-05-26 | Preprint
DOI: 10.22541/au.168508096.62865709/v1
Contributors: Joan Cortada Garcia; Jennifer Haggarty; Stefan Weidt; Ronan Daly; Alison Arnold; Karl Burgess
Source: check_circle
Crossref

On‐line untargeted metabolomics monitoring of an Escherichia coli succinate fermentation process

Biotechnology and Bioengineering
2022-10 | Journal article
DOI: 10.1002/bit.28173
Contributors: Joan Cortada‐Garcia; Jennifer Haggarty; Tessa Moses; Rónán Daly; Susan Alison Arnold; Karl Burgess
Source: check_circle
Crossref

Rapid HILIC-Z ion mobility mass spectrometry (RHIMMS) method for untargeted metabolomics of complex biological samples

Metabolomics
2022-03 | Journal article
DOI: 10.1007/s11306-022-01871-1
Contributors: Martina Pičmanová; Tessa Moses; Joan Cortada-Garcia; Georgina Barrett; Hannah Florance; Sufyan Pandor; Karl Burgess
Source: check_circle
Crossref

Ranking Metabolite Sets by Their Activity Levels

Metabolites
2021-02-11 | Journal article
DOI: 10.3390/metabo11020103
Contributors: Karen McLuskey; Joe Wandy; Isabel Vincent; Justin J. J. van der Hooft; Simon Rogers; Karl Burgess; Rónán Daly
Source: check_circle
Crossref

Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering

bioRxiv
2020 | Journal article
Source: Self-asserted source
Karl Burgess

Schistosoma haematobium infection is associated with alterations in energy and purine-related metabolism in preschool-aged children

PLOS Neglected Tropical Diseases
2020-12-14 | Journal article
DOI: 10.1371/journal.pntd.0008866
Contributors: Derick N. M. Osakunor; Aaron R. Jex; Takafira Mduluza; Douglas Osei-Hyiaman; Karl Burgess; Mark E. J. Woolhouse; Francisca Mutapi
Source: check_circle
Crossref

Decomposing metabolite set activity levels with PALS

2020-06-08 | Preprint
DOI: 10.1101/2020.06.07.138974
Contributors: Karen McLuskey; Joe Wandy; Isabel Vincent; Justin J.J. van der Hooft; Simon Rogers; Karl Burgess; Rónán Daly
Source: check_circle
Crossref

Functional colour genes and signals of selection in colour‐polymorphic salamanders

Molecular Ecology
2020-04 | Journal article
DOI: 10.1111/mec.15411
Contributors: James D. Burgon; David R. Vieites; Arne Jacobs; Stefan K. Weidt; Helen M. Gunter; Sebastian Steinfartz; Karl Burgess; Barbara K. Mable; Kathryn R. Elmer
Source: check_circle
Crossref

High-throughput quantification of carboxymethyl lysine in serum and plasma using high-resolution accurate mass Orbitrap mass spectrometry

Annals of clinical biochemistry
2019 | Journal article
Source: Self-asserted source
Karl Burgess

Multi-layer controls of Cas9 activity coupled with ATP synthase over-expression for efficient genome editing in Streptomyces

Frontiers in bioengineering and biotechnology
2019 | Journal article
Source: Self-asserted source
Karl Burgess

Nanotopography reveals metabolites that maintain the immunosuppressive phenotype of mesenchymal stem cells

bioRxiv
2019 | Journal article
Source: Self-asserted source
Karl Burgess

Pharmacometabolomics of meglumine antimoniate in patients with cutaneous leishmaniasis

Frontiers in pharmacology
2019 | Journal article
Source: Self-asserted source
Karl Burgess

Substantial extracellular metabolic differences found between phylogenetically closely related probiotic and pathogenic strains of Escherichia coli

Frontiers in microbiology
2019 | Journal article
Source: Self-asserted source
Karl Burgess

Changing environments and genetic variation: natural variation in inbreeding does not compromise short-term physiological responses

Proceedings of the Royal Society B: Biological Sciences
2019-11-20 | Journal article
DOI: 10.1098/rspb.2019.2109
Contributors: James Buckley; Rónán Daly; Christina A. Cobbold; Karl Burgess; Barbara K. Mable
Source: check_circle
Crossref

Plasma Itaconate elevation following successful cDMARD treatment in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation

2019-07-08 | Other
DOI: 10.1101/19001594
Contributors: Rónán Daly; Gavin Blackburn; Manikhandan Mudaliar; Karl Burgess; Anne Stirling; Duncan Porter; Iain McInnes; Michael P. Barrett; James Dale
Source: check_circle
Crossref

PHARMACO-METABOLOMICS OF BLOOD PRESSURE RESPONSE TO BETA-BLOCKERS AND DIURETICS

Journal of Hypertension
2018 | Journal article
Source: Self-asserted source
Karl Burgess

Unexpected differential metabolic responses of Campylobacter jejuni to the abundant presence of glutamate and fucose

Metabolomics
2018 | Journal article
Source: Self-asserted source
Karl Burgess

MetaboCraft: building a Minecraft plugin for metabolomics

Bioinformatics
2018-08-01 | Journal article
DOI: 10.1093/bioinformatics/bty102
Contributors: Anargyros Megalios; Rónán Daly; Karl Burgess; Janet Kelso
Source: check_circle
Crossref

Minimally-destructive atmospheric ionisation mass spectrometry authenticates authorship of historical manuscripts

Scientific Reports
2018-07-26 | Journal article
DOI: 10.1038/s41598-018-28810-2
Contributors: James Newton; Gordon Ramage; Nikolaj Gadegaard; William Zachs; Simon Rogers; Michael P. Barrett; Gerard Carruthers; Karl Burgess
Source: check_circle
Crossref

Candida albicans mycofilms support Staphylococcus aureus colonization and enhances miconazole resistance in dual-species interactions

Frontiers in microbiology
2017 | Journal article
Source: Self-asserted source
Karl Burgess

Improving cartilage phenotype from differentiated pericytes in tunable peptide hydrogels

Scientific reports
2017 | Journal article
Source: Self-asserted source
Karl Burgess

Integration of proteomics and metabolomics to elucidate metabolic adaptation in Leishmania

Journal of proteomics
2017 | Journal article
Source: Self-asserted source
Karl Burgess

MetaNetter 2: A Cytoscape plugin for ab initio network analysis and metabolite feature classification

Journal of Chromatography B
2017 | Journal article
Source: Self-asserted source
Karl Burgess

Nacre Topography Produces Higher Crystallinity in Bone than Chemically Induced Osteogenesis

ACS nano
2017 | Journal article
Source: Self-asserted source
Karl Burgess

Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency

Biomaterials
2017 | Journal article
Source: Self-asserted source
Karl Burgess

Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition

Molecular microbiology
2017 | Journal article
Source: Self-asserted source
Karl Burgess

PiMP my metabolome: an integrated, web-based tool for LC-MS metabolomics data

Bioinformatics
2017 | Journal article
Source: Self-asserted source
Karl Burgess

Sterol 14$α$-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana

PLoS neglected tropical diseases
2017 | Journal article
Source: Self-asserted source
Karl Burgess

Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor

Nature Biomedical Engineering
2017 | Journal article
Source: Self-asserted source
Karl Burgess

The mitochondrial prohibitin complex, a context-dependent modulator of longevity, has broad effects in the C. elegans metabolome, suggesting a remodelling of the mitochondrial respiratory chain

2017 | Journal article
Source: Self-asserted source
Karl Burgess

Unsupervised discovery and comparison of structural families across multiple samples in untargeted metabolomics

Analytical chemistry
2017 | Journal article
Source: Self-asserted source
Karl Burgess

Recent advances in liquid and gas chromatography methodology for extending coverage of the metabolome

Current Opinion in Biotechnology
2017-02 | Journal article
DOI: 10.1016/j.copbio.2016.09.006
Contributors: Jennifer Haggarty; Karl EV Burgess
Source: check_circle
Crossref

A novel metabolomic approach used for the comparison of Staphylococcus aureus planktonic cells and biofilm samples

Metabolomics
2016 | Journal article
Source: Self-asserted source
Karl Burgess

Dynamic surfaces for the study of mesenchymal stem cell growth through adhesion regulation

ACS nano
2016 | Journal article
Source: Self-asserted source
Karl Burgess

Glycolysis and pyrimidine biosynthesis are required for replication of adherent--invasive Escherichia coli in macrophages

Microbiology
2016 | Journal article
Source: Self-asserted source
Karl Burgess

Integrating Candida albicans metabolism with biofilm heterogeneity by transcriptome mapping

Scientific reports
2016 | Journal article
Source: Self-asserted source
Karl Burgess

Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 3. Untargeted metabolomics

Molecular BioSystems
2016 | Journal article
Source: Self-asserted source
Karl Burgess

Topic modeling for untargeted substructure exploration in metabolomics

Proceedings of the National Academy of Sciences
2016 | Journal article
Source: Self-asserted source
Karl Burgess

Tunable supramolecular hydrogels for selection of lineage-guiding metabolites in stem cell cultures

Chem
2016 | Journal article
Source: Self-asserted source
Karl Burgess

Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation

Metabolomics
2016 | Journal article
Source: Self-asserted source
Karl Burgess

A novel targeted/untargeted GC-Orbitrap metabolomics methodology applied to Candida albicans and Staphylococcus aureus biofilms

Metabolomics
2016-12 | Journal article
DOI: 10.1007/s11306-016-1134-2
Contributors: Stefan Weidt; Jennifer Haggarty; Ryan Kean; Cristian I. Cojocariu; Paul J. Silcock; Ranjith Rajendran; Gordon Ramage; Karl E. V. Burgess
Source: check_circle
Crossref

Asymmetric cell division and its role in cell fate determination in the green alga Tetraselmis indica

Journal of biosciences
2015 | Journal article
Source: Self-asserted source
Karl Burgess

Draft genome sequence of isolate Staphylococcus aureus LHSKBClinical, isolated from an infected hip

Genome Announc.
2015 | Journal article
Source: Self-asserted source
Karl Burgess

Enhanced acylcarnitine annotation in high-resolution mass spectrometry data: fragmentation analysis for the classification and annotation of acylcarnitines.

2015 | Journal article
DOI: 10.3389/fbioe.2015.00026
PMID: 25806366
PMC: PMC4353373
Contributors: van der Hooft JJ; Ridder L; Barrett MP; Burgess KE
Source: Self-asserted source
Karl Burgess via Europe PubMed Central

LC--MS-based absolute metabolite quantification: application to metabolic flux measurement in trypanosomes

Metabolomics
2015 | Journal article
Source: Self-asserted source
Karl Burgess

Potent trypanocidal curcumin analogs bearing a monoenone linker motif act on Trypanosoma brucei by forming an adduct with trypanothione

Molecular pharmacology
2015 | Journal article
Source: Self-asserted source
Karl Burgess
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Peer review (7 reviews for 5 publications/grants)

Review activity for ACS omega. (1)
Review activity for Analytical chemistry. (2)
Review activity for Chromatographia. (1)
Review activity for Metabolomics. (2)
Review activity for Nature communications (1)
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