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Metabolism, Cofactor Enzymology, Redox Biology
Germany

Activities

Employment (4)

Universitätsklinikum Freiburg: Freiburg, Baden-Württemberg, DE

2015-11-01 to present | Research Group Leader (Zentrum für Kinder-und Jugendmedizin)
Employment
Source: Self-asserted source
Luciana Hannibal

Friedrich-Alexander-Universität Erlangen-Nürnberg: Erlangen, Bayern, DE

2014-09-01 to 2015-04-30 | DAAD-Sponsored Visiting Lecturer (Bioinorganic Chemistry)
Employment
Source: Self-asserted source
Luciana Hannibal

Cleveland Clinic: Cleveland, OH, US

2012-10-01 to 2014-08-31 | Research Associate/Junior Staff (Department of Pathobiology)
Employment
Source: Self-asserted source
Luciana Hannibal

Cleveland Clinic: Cleveland, OH, US

2009-07-01 to 2012-09-01 | Postdoctoral research fellow (Department of Pathology)
Employment
Source: Self-asserted source
Luciana Hannibal

Education and qualifications (2)

Kent State University: Kent, OH, US

2005-07-16 to 2009-08-22 | PhD Molecular and Cellular Biology (School of Biomedical Sciences)
Education
Source: Self-asserted source
Luciana Hannibal

Universidad de la Republica : Montevideo, UY

1998-03 to 2004-09 | BSc Biochemistry (Faculty of Sciences)
Education
Source: Self-asserted source
Luciana Hannibal

Professional activities (4)

German Association for Paediatric Metabolic Disorders (APS): Reutlingen , DE

Membership
Source: Self-asserted source
Luciana Hannibal

European network and registry for Homocystinurias and methylation Defects (EHOD): Heidelberg, Baden-Wuerttemberg, DE

Scientific Board Member
Membership
Source: Self-asserted source
Luciana Hannibal

Society for the Study of Inborn Errors of Metabolism: London, GB

2016 to present | Scientist
Membership
Source: Self-asserted source
Luciana Hannibal

Society for Redox Biology and Medicine: Indianapolis, IN, US

2015 to present | Council Member and Committee Chair (Nominations and Leadership)
Service
Source: Self-asserted source
Luciana Hannibal

Funding (3)

Translational Metabolomics -Mass spectrometry platform

2021-08 to present | Grant
Universitätsklinikum Freiburg (Freiburg, Baden-Wuerttemberg, DE)
Source: Self-asserted source
Luciana Hannibal

Bioactive cobalamins for the treatment of genetic and age-related vitamin B12 deficiency.

2020-11 to present | Grant
Bundesministerium für Wirtschaft und Energie (Berlin, DE)
Source: Self-asserted source
Luciana Hannibal

Profiling of cobalamin forms in the ageing muscle

2017 to present | Grant
NIHS (Lausanne, CH)
Source: Self-asserted source
Luciana Hannibal

Works (50 of 99)

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Analyzing dietary exposure to critical nutrients on a plant-based diet using the food- and total nutrient index

Nutrition Journal
2025-03-12 | Journal article
Contributors: Maximilian Andreas Storz; Frieda Stübing; Luciana Hannibal; Roman Huber
Source: check_circle
Crossref

The cobalamin processing enzyme of Trichoplax adhaerens

Journal of Biological Chemistry
2025-02 | Journal article
Contributors: Caroline Krams; Anna J. Esser; Melissa Klenzendorf; Katharina Klotz; Ute Spiekerkoetter; Donald W. Jacobsen; Clyde A. Smith; Ailiena O. Maggiolo; Luciana Hannibal
Source: check_circle
Crossref

Cystathionine β‐Synthase Deficiency in the E‐HOD Registry—Part II: Dietary and Pharmacological Treatment

Journal of Inherited Metabolic Disease
2025-01 | Journal article
Contributors: Andrew A. M. Morris; Jitka Sokolová; Markéta Pavlíková; Florian Gleich; Stefan Kölker; Carlo Dionisi‐Vici; Matthias R. Baumgartner; Luciana Hannibal; Henk J. Blom; Martina Huemer et al.
Source: check_circle
Crossref

Bowel health, defecation patterns and nutrient intake following adoption of a vegan diet: a randomized-controlled trial

Annals of Medicine
2024-12-31 | Journal article
Contributors: Julian Herter; Frieda Stübing; Volker Lüth; Julia Zimmermann; Ann-Kathrin Lederer; Luciana Hannibal; Roman Huber; Maximilian Andreas Storz
Source: check_circle
Crossref

Real-time detection of enzymatically formed hydrogen sulfide by pathogenic variants of cystathionine beta-synthase using hemoglobin I of Lucina pectinata as a biosensor

Free Radical Biology and Medicine
2024-10 | Journal article
Contributors: Joanna Myszkowska; Katharina Klotz; Paula Leandro; Warren D. Kruger; D. Sean Froese; Matthias R. Baumgartner; Ute Spiekerkoetter; Luciana Hannibal
Source: check_circle
Crossref

Patient-Reported Characteristics of Pernicious Anaemia:A first step to initiate James Lind Alliance Priority Setting Partnership Driven Research

2024-08-31 | Preprint
Contributors: Alfie Thain; Petra Visser; Kathryn Hart; Ebba Nexo; Andrew McCaddon; Luciana Hannibal; Bruce HR Wolffenbuttel; Ralph Green; Nicola Ward; Catherine Heidi Seage et al.
Source: check_circle
Crossref

Depression with anti-myelin antibodies in the cerebrospinal fluid

Molecular Psychiatry
2024-06 | Journal article
Contributors: Dominique Endres; Lea Berninger; Cornelia Glaser; Luciana Hannibal; Benjamin Berger; Kathrin Nickel; Kimon Runge; Marco Reisert; Horst Urbach; Katharina Domschke et al.
Source: check_circle
Crossref

Vitamin B12 Status and Supplementation in Plant-Based Diets

Food and Nutrition Bulletin
2024-06 | Journal article
Contributors: Luciana Hannibal; Ann-Kathrin Lederer; Maximilian A. Storz; Roman Huber; Donald W. Jacobsen
Source: check_circle
Crossref

A systematic review of metabolomic findings in adult and pediatric renal disease

Clinical Biochemistry
2024-01 | Journal article
Contributors: Lennart Moritz; Anke Schumann; Martin Pohl; Anna Köttgen; Luciana Hannibal; Ute Spiekerkoetter
Source: check_circle
Crossref

A cross-sectional study of nutritional status in healthy, young, physically-active German omnivores, vegetarians and vegans reveals adequate vitamin B<sub>12</sub> status in supplemented vegans

Annals of Medicine
2023 | Journal article
EID:

2-s2.0-85174572699

Part of ISSN: 13652060 07853890
Contributors: Storz, M.A.; Müller, A.; Niederreiter, L.; Zimmermann-Klemd, A.M.; Suarez-Alvarez, M.; Kowarschik, S.; Strittmatter, M.; Schlachter, E.; Pasluosta, C.; Huber, R. et al.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

Editorial: Methods in Metabolomics 2022

Frontiers in Molecular Biosciences
2023 | Journal article
EID:

2-s2.0-85150822952

Part of ISSN: 2296889X
Contributors: Buescher, J.; Hannibal, L.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

Metabolic phenotyping in phenylketonuria reveals disease clustering independently of metabolic control

Molecular Genetics and Metabolism
2023 | Journal article
EID:

2-s2.0-85147858551

Part of ISSN: 10967206 10967192
Contributors: Moritz, L.; Klotz, K.; Grünert, S.C.; Hannibal, L.; Spiekerkoetter, U.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

The impact of metabolic stressors on mitochondrial homeostasis in a renal epithelial cell model of methylmalonic aciduria

Scientific Reports
2023 | Journal article
EID:

2-s2.0-85159207575

Part of ISSN: 20452322
Contributors: Schumann, A.; Brutsche, M.; Havermans, M.; Grünert, S.C.; Kölker, S.; Groß, O.; Hannibal, L.; Spiekerkoetter, U.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

The importance of vitamin B<sub>12</sub> for individuals choosing plant-based diets

European Journal of Nutrition
2023 | Journal article
EID:

2-s2.0-85143372478

Contributors: Niklewicz, A.; Smith, A.D.; Smith, A.; Holzer, A.; Klein, A.; McCaddon, A.; Molloy, A.M.; Wolffenbuttel, B.H.R.; Nexo, E.; McNulty, H. et al.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

Spic regulates one-carbon metabolism and histone methylation in ground-state pluripotency

Science Advances
2023-08-18 | Journal article
Contributors: Fatemeh Mirzadeh Azad; Eduard A. Struys; Victoria Wingert; Luciana Hannibal; Ken Mills; Joop H. Jansen; Daniel B. Longley; Hendrik G. Stunnenberg; Yaser Atlasi
Source: check_circle
Crossref
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Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8<sup>+</sup> T cells.

Gut
2023-08-04 | Journal article
Contributors: Winkler F; Hipp AV; Ramirez C; Martin B; Villa M; Emilia Neuwirt; Gorka O; Aerssens J; Johansson SE; Rana N et al.
Source: Self-asserted source
Luciana Hannibal
grade
Preferred source (of 2)‎

Dietary Acid Load Correlates with Serum Amino Acid Concentrations after a Four-Week Intervention with Vegan vs. Meat-Rich Diets: A Secondary Data Analysis

Nutrients
2023-06-28 | Journal article
Contributors: Julian Herter; Ann-Kathrin Lederer; Alvaro Luis Ronco; Luciana Hannibal; Roman Huber; Maximilian Andreas Storz
Source: check_circle
Crossref
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Deep clinical phenotyping of patients with obsessive-compulsive disorder: an approach towards detection of organic causes and first results

Translational Psychiatry
2023-03-07 | Journal article
Contributors: Kimon Runge; Marco Reisert; Bernd Feige; Kathrin Nickel; Horst Urbach; Nils Venhoff; Andreas Tzschach; Miriam A. Schiele; Luciana Hannibal; Harald Prüss et al.
Source: check_circle
Crossref
grade
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Case Report: Possible autoimmune obsessive-compulsive disorder with postpartum onset

Frontiers in Immunology
2022 | Journal article
EID:

2-s2.0-85137874820

Part of ISSN: 16643224
Contributors: Endres, D.; Hannibal, L.; Zaltenbach, B.; Schiele, M.A.; Runge, K.; Nickel, K.; Berger, B.; Domschke, K.; Venhoff, N.; Prüss, H. et al.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

De novo sequencing and construction of a unique antibody for the recognition of alternative conformations of cytochrome c in cells

Proceedings of the National Academy of Sciences of the United States of America
2022 | Journal article
EID:

2-s2.0-85142400928

Part of ISSN: 10916490 00278424
Contributors: Tomasina, F.; Martínez, J.; Zeida, A.; Chiribao, M.L.; Demicheli, V.; Correa, A.; Quijano, C.; Castro, L.; Carnahan, R.H.; Vinson, P. et al.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

Fatty acid metabolism in aggressive B-cell lymphoma is inhibited by tetraspanin CD37

Nature Communications
2022 | Journal article
EID:

2-s2.0-85137810420

Part of ISSN: 20411723
Contributors: Peeters, R.; Cuenca-Escalona, J.; Zaal, E.A.; Hoekstra, A.T.; Balvert, A.C.G.; Vidal-Manrique, M.; Blomberg, N.; van Deventer, S.J.; Stienstra, R.; Jellusova, J. et al.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

Intracellular processing of vitamin B<sub>12</sub> by MMACHC (CblC)

Vitamins and Hormones
2022 | Book
EID:

2-s2.0-85126562450

Contributors: Hannibal, L.; Jacobsen, D.W.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

Observational and clinical evidence that plant-based nutrition reduces dietary acid load

Journal of Nutritional Science
2022 | Journal article
Contributors: Maximilian A. Storz; Alvaro L. Ronco; Luciana Hannibal
Source: check_circle
Crossref
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Versatile enzymology and heterogeneous phenotypes in cobalamin complementation type C disease

iScience
2022-09 | Journal article
Contributors: Anna J. Esser; Srijan Mukherjee; Ilia A. Dereven’kov; Sergei V. Makarov; Donald W. Jacobsen; Ute Spiekerkoetter; Luciana Hannibal
Source: check_circle
Crossref
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Plasma Leptin and Adiponectin after a 4-Week Vegan Diet: A Randomized-Controlled Pilot Trial in Healthy Participants

International Journal of Environmental Research and Public Health
2022-09-09 | Journal article
Contributors: Ann-Kathrin Lederer; Maximilian Andreas Storz; Roman Huber; Luciana Hannibal; Elena Neumann
Source: check_circle
Crossref
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Methionine Adenosyltransferase I/III Deficiency Detected by Newborn Screening

Genes
2022-06-27 | Journal article
Contributors: Vanessa Hübner; Luciana Hannibal; Nils Janzen; Sarah Catharina Grünert; Peter Freisinger
Source: check_circle
Crossref
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Analysis of S-Adenosylmethionine and S-Adenosylhomocysteine: Method Optimisation and Profiling in Healthy Adults upon Short-Term Dietary Intervention

Metabolites
2022-04 | Journal article | Author
Contributors: Aida Corrillero Bravo; María Nieves Ligero Aguilera; Nahuel R. Marziali; Lennart Moritz; Victoria Wingert; Katharina Klotz; Anke Schumann; Sarah C. Grünert; Ute Spiekerkoetter; Urs Berger et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Optimized Biocompatible Gold Nanotriangles with NIR Absorption for Photothermal Applications

ACS Applied Nano Materials
2022-01-28 | Journal article
Contributors: Camila M. Otero; Guillermina Boggan Simal; Magalí F. Scocozza; Aldo Rubert; Claudia A. Grillo; Luciana Hannibal; Gabriel Lavorato; María Ana Huergo; Daniel H. Murgida; Carolina Vericat
Source: check_circle
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Glycogen storage disease type I patients with hyperlipidemia have no signs of early vascular dysfunction and premature atherosclerosis

Nutrition, Metabolism and Cardiovascular Diseases
2021 | Journal article
EID:

2-s2.0-85116607091

Part of ISSN: 15903729 09394753
Contributors: Schmitt, J.; Wurm, M.; Schwab, K.O.; Spiekerkoetter, U.; Hannibal, L.; Grünert, S.C.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

Inhibition of metabotropic glutamate receptor III facilitates sensitization to alkylating chemotherapeutics in glioblastoma

Cell Death and Disease
2021 | Journal article
EID:

2-s2.0-85111126523

Part of ISSN: 20414889
Contributors: Maier, J.P.; Ravi, V.M.; Kueckelhaus, J.; Behringer, S.P.; Garrelfs, N.; Will, P.; Sun, N.; von Ehr, J.; Goeldner, J.M.; Pfeifer, D. et al.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

Mitochondrial damage in renal epithelial cells is potentiated by protein exposure in propionic aciduria

Journal of Inherited Metabolic Disease
2021 | Journal article
EID:

2-s2.0-85112542400

Part of ISSN: 15732665 01418955
Contributors: Schumann, A.; Belche, V.; Schaller, K.; Grünert, S.C.; Kaech, A.; Baumgartner, M.R.; Kölker, S.; Hannibal, L.; Spiekerkoetter, U.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

Oncometabolite R-2 hydroxyglutarate aids the inflammatory transformation of peritumoral astrocytes

Research Square
2021 | Other
EID:

2-s2.0-85166499970

Contributors: Ravi, V.M.; Behringer, S.P.; Joseph, K.; Hannibal, L.; Kueckelhaus, J.; Will, P.; Neidert, N.; Goeldner, J.M.; Franco, P.; Fung, C. et al.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

Successful pregnancy in a woman with glycogen storage disease type 6

Molecular Genetics and Metabolism Reports
2021 | Journal article
EID:

2-s2.0-85105457649

Part of ISSN: 22144269
Contributors: Grünert, S.C.; Rosenbaum-Fabian, S.; Hannibal, L.; Schumann, A.; Spiekerkoetter, U.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

Three successful pregnancies in a patient with glycogen storage disease type 0

JIMD Reports
2021 | Book
EID:

2-s2.0-85099435850

Part of ISSN: 21928312 21928304
Contributors: Grünert, S.C.; Rosenbaum-Fabian, S.; Hannibal, L.; Schumann, A.; Spiekerkötter, U.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

A Vegan Diet Is Associated with a Significant Reduction in Dietary Acid Load: Post Hoc Analysis of a Randomized Controlled Trial in Healthy Individuals

International Journal of Environmental Research and Public Health
2021-09-23 | Journal article
Contributors: Alexander Müller; Amy Marisa Zimmermann-Klemd; Ann-Kathrin Lederer; Luciana Hannibal; Stefanie Kowarschik; Roman Huber; Maximilian Andreas Storz
Source: check_circle
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Elevated holo‐transcobalamin in Gaucher disease type II: A case report

American Journal of Medical Genetics Part A
2021-08 | Journal article
Contributors: Suelen Porto Basgalupp; Karina Carvalho Donis; Marina Siebert; Filippo Pinto e Vairo; Osvaldo Artigalas; Louise L. de Camargo Pinto; Sidney Behringer; Ute Spiekerkoetter; Luciana Hannibal; Ida Vanessa D. Schwartz
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The Phenotypic and Genetic Spectrum of Glycogen Storage Disease Type VI

Genes
2021-08-03 | Journal article
Contributors: Sarah Catharina Grünert; Luciana Hannibal; Ute Spiekerkoetter
Source: check_circle
Crossref
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Biosynthesis, Quantification and Genetic Diseases of the Smallest Signaling Thiol Metabolite: Hydrogen Sulfide

Antioxidants
2021-07-01 | Journal article
Contributors: Joanna Myszkowska; Ilia Derevenkov; Sergei V. Makarov; Ute Spiekerkoetter; Luciana Hannibal
Source: check_circle
Crossref
grade
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Mechanism of cyanocobalamin chlorination by hypochlorous acid

JBIC Journal of Biological Inorganic Chemistry
2021-06-29 | Journal article
Contributors: Ilia A. Dereven’kov; Vladimir S. Osokin; Luciana Hannibal; Sergei V. Makarov; Ilya A. Khodov; Oskar I. Koifman
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Changes in Gut Microbiota after a Four-Week Intervention with Vegan vs. Meat-Rich Diets in Healthy Participants: A Randomized Controlled Trial

Microorganisms
2021-03-31 | Journal article
Contributors: Eva Kohnert; Clemens Kreutz; Nadine Binder; Luciana Hannibal; Gregor Gorkiewicz; Alexander Müller; Maximilian Andreas Storz; Roman Huber; Ann-Kathrin Lederer
Source: check_circle
Crossref
grade
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Identification and Characterization of a Novel Splice Site Mutation Associated with Glycogen Storage Disease Type VI in Two Unrelated Turkish Families

Diagnostics
2021-03-12 | Journal article
Contributors: Sarah C. Grünert; Luciana Hannibal; Anke Schumann; Stefanie Rosenbaum-Fabian; Stefanie Beck-Wödl; Tobias B. Haack; Mona Grimmel; Miriam Bertrand; Ute Spiekerkoetter
Source: check_circle
Crossref
grade
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Defective lysosomal storage in Fabry Disease modifies mitochondrial structure, metabolism and turnover in renal epithelial cells.

Journal of inherited metabolic disease
2021-03-04 | Journal article
Source: Self-asserted source
Luciana Hannibal
grade
Preferred source (of 2)‎

Citrin deficiency mimicking mitochondrial depletion syndrome

BMC Pediatrics
2020 | Journal article
EID:

2-s2.0-85095846404

Part of ISBN:

14712431

Contributors: Grünert, S.C.; Schumann, A.; Freisinger, P.; Rosenbaum-Fabian, S.; Schmidts, M.; Mueller, A.J.; Beck-Wödl, S.; Haack, T.B.; Schneider, H.; Fuchs, H. et al.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

Improved inflammatory bowel disease, wound healing and normal oxidative burst under treatment with empagliflozin in glycogen storage disease type Ib

Orphanet Journal of Rare Diseases
2020 | Journal article
EID:

2-s2.0-85089929266

Part of ISBN:

17501172

Contributors: Grünert, S.C.; Elling, R.; Maag, B.; Wortmann, S.B.; Derks, T.G.J.; Hannibal, L.; Schumann, A.; Rosenbaum-Fabian, S.; Spiekerkoetter, U.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

Metabolic Profiling in Human Fibroblasts Enables Subtype Clustering in Glycogen Storage Disease

Frontiers in Endocrinology
2020 | Journal article
EID:

2-s2.0-85097293738

Part of ISSN: 16642392
Contributors: Hannibal, L.; Theimer, J.; Wingert, V.; Klotz, K.; Bierschenk, I.; Nitschke, R.; Spiekerkoetter, U.; Grünert, S.C.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

The Effect of A 4-Week Vegan Diet on Adipokine Levels in Healthy Male and Female Participants: A Randomized-Controlled Trial

Research Square
2020 | Other
EID:

2-s2.0-85166686528

Contributors: Lederer, A.-K.; Hettich, M.; Huber, R.; Hannibal, L.; Neumann, E.
Source: Self-asserted source
Luciana Hannibal via Scopus - Elsevier

Thiolatocobalamins repair the activity of pathogenic variants of the human cobalamin processing enzyme CblC.

Biochimie
2020-10-22 | Journal article
Source: Self-asserted source
Luciana Hannibal
grade
Preferred source (of 2)‎

Elevated Plasma Vitamin B12 in Patients with Hepatic Glycogen Storage Diseases

Journal of Clinical Medicine
2020-07-22 | Journal article
Contributors: Julia Hinkel; Johannes Schmitt; Michael Wurm; Stefanie Rosenbaum-Fabian; Karl Otfried Schwab; Donald W. Jacobsen; Ute Spiekerkoetter; Sergey N. Fedosov; Luciana Hannibal; Sarah C. Grünert
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DNMT3B deficiency alters mitochondrial biogenesis and α-ketoglutarate levels in human embryonic stem cells.

Stem cells (Dayton, Ohio)
2020-07-11 | Journal article
Source: Self-asserted source
Luciana Hannibal
grade
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Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation.

iScience
2020-05-11 | Journal article
Source: Self-asserted source
Luciana Hannibal
grade
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Page 1 of 2

Peer review (6 reviews for 5 publications/grants)

Review activity for BMC pediatrics (1)
Review activity for Metabolites. (1)
Review activity for Molecular genetics and metabolism. (1)
Review activity for Nutrients. (2)
Review activity for The Lancet regional health. (1)