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Works (4)

Co-targeting SOS1 enhances the antitumor effects of KRASG12C inhibitors by addressing intrinsic and acquired resistance

Nature Cancer
2024-08-05 | Journal article | Author
DOI: 10.1038/s43018-024-00800-6
Part of ISSN: 2662-1347
Contributors: Venu Thatikonda; Hengyu Lu; Sabine Jurado; Kaja Kostyrko; Christopher A. Bristow; Christoph Albrecht; Donat Alpar; Heribert Arnhof; Oliver Bergner; Karin Bosch et al.
Source: Self-asserted source
Melanie

Reshaping the Tumor Microenvironment of KRASG12D Pancreatic Ductal Adenocarcinoma with Combined SOS1 and MEK Inhibition for Improved Immunotherapy Response

Cancer Research Communications
2024-06-21 | Journal article | Author
DOI: 10.1158/2767-9764.crc-24-0172
Part of ISSN: 2767-9764
Contributors: Robert Norgard; Pratha Budhani; Sarah O'Brien; Youli Xia; Jessica Egan Potts; Brianna Flynn; Joshua Tagore; Joseph Seco; Gregory W. Peet; Ania Mikucka Ania Mikucka et al.
Source: Self-asserted source
Melanie via Crossref Metadata Search

Drugging All RAS Isoforms With One Pocket

Future Medicinal Chemistry
2020-11 | Journal article
DOI: 10.4155/fmc-2020-0221
Contributors: Dirk Kessler; Andreas Bergner; Jark Böttcher; Gerhard Fischer; Sandra Döbel; Melanie Hinkel; Barbara Müllauer; Alexander Weiss-Puxbaum; Darryl B McConnell
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Crossref

Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers

Nature Genetics
2019-09 | Journal article
DOI: 10.1038/s41588-019-0477-9
Contributors: Sandra Schick; André F. Rendeiro; Kathrin Runggatscher; Anna Ringler; Bernd Boidol; Melanie Hinkel; Peter Májek; Loan Vulliard; Thomas Penz; Katja Parapatics et al.
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Crossref
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