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Scopus Author ID: 57195419254

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Employment (3)

Göteborgs Universitet: Goteborg, SE

2014-09-01 to present | Scientist (Institute of Medicine)
Employment
Source: Self-asserted source
Barbara Becattini

Université de Fribourg: Fribourg, FR, CH

2007-11-01 to 2014-06-30 | Research Associate (Medicine)
Employment
Source: Self-asserted source
Barbara Becattini

Sanford-Burnham Medical Research Institute: La Jolla, CA, US

2003-03-01 to 2007-06-30 | Post-doc
Employment
Source: Self-asserted source
Barbara Becattini

Education and qualifications (2)

University of Berne: Berne, CH

1999-11-01 to 2003-01-23 | Ph.D. (Chemistry)
Education
Source: Self-asserted source
Barbara Becattini

Università degli Studi di Firenze: Firenze, Toscana, IT

1993-09-01 to 1999-06-30 | M.Sc. (Pharmaceutical Chemistry and Technology)
Education
Source: Self-asserted source
Barbara Becattini

Works (37)

Activation of GFRAL<sup>+</sup> neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor

Cell Reports
2024 | Journal article
DOI: 10.1016/j.celrep.2024.113960
EID:

2-s2.0-85188124228

Part of ISSN: 22111247
Contributors: Engström Ruud, L.; Font-Gironès, F.; Zajdel, J.; Kern, L.; Teixidor-Deulofeu, J.; Mannerås-Holm, L.; Carreras, A.; Becattini, B.; Björefeldt, A.; Hanse, E. et al.
Source: Self-asserted source
Barbara Becattini via Scopus - Elsevier

Adipocyte PI3K links adipostasis with baseline insulin secretion at fasting through an adipoincretin effect

Cell Reports
2024 | Journal article
DOI: 10.1016/j.celrep.2024.114132
EID:

2-s2.0-85190878499

Part of ISSN: 22111247
Contributors: Becattini, B.; Molinaro, A.; Henricsson, M.; Borén, J.; Solinas, G.
Source: Self-asserted source
Barbara Becattini via Scopus - Elsevier

An adipoincretin effect links adipostasis with insulin secretion

Trends in Endocrinology & Metabolism
2024-06 | Journal article
DOI: 10.1016/j.tem.2023.10.009
Contributors: Giovanni Solinas; Barbara Becattini
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Crossref

Adipocyte PI3K links adipostasis with basal insulin secretion through an adipoincretin effect

Research Square
2023 | Other
DOI: 10.21203/rs.3.rs-2986961
EID:

2-s2.0-85169715004
Contributors: Becattini, B.; Molinaro, A.; Henricsson, M.; Boren, J.; Solinas, G.
Source: Self-asserted source
Barbara Becattini via Scopus - Elsevier

Adipocyte PI3K Links Adipostasis with Basal Insulin Secretion Through an Adipoincretin Effect

2023-04-26 | Preprint
DOI: 10.1101/2023.04.24.538076
Contributors: Barbara Becattini; Angela Molinaro; Marcus Henricsson; Jan Borén; Giovanni Solinas
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PI3K and AKT at the Interface of Signaling and Metabolism

Current Topics in Microbiology and Immunology
2022 | Book chapter
DOI: 10.1007/978-3-031-06566-8_13
EID:

2-s2.0-85139888212

Part of ISSN: 21969965 0070217X
Contributors: Solinas, G.; Becattini, B.
Source: Self-asserted source
Barbara Becattini via Scopus - Elsevier

PSD3 downregulation confers protection against fatty liver disease

Nature Metabolism
2022 | Journal article
DOI: 10.1038/s42255-021-00518-0
EID:

2-s2.0-85123974742

Part of ISSN: 25225812
Contributors: Mancina, R.M.; Sasidharan, K.; Lindblom, A.; Wei, Y.; Ciociola, E.; Jamialahmadi, O.; Pingitore, P.; Andréasson, A.-C.; Pellegrini, G.; Baselli, G. et al.
Source: Self-asserted source
Barbara Becattini via Scopus - Elsevier

Somatic ablation of IKKβ in liver and leukocytes is not tolerated in obese mice but hepatic IKKβ deletion improves fatty liver and insulin sensitivity

The FASEB Journal
2022-09 | Journal article
DOI: 10.1096/fj.202200694R
Contributors: Vagner Ramon R. Silva; Angela Molinaro; Andrea Usseglio Gaudi; Emanuel Fryk; Claudia Sardi; Maria Hammarlund; Filip Mjörnstedt; Maria E. Johansson; Barbara Becattini; Per‐Anders Jansson et al.
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JNK1 ablation improves pancreatic β-cell mass and function in db/db diabetic mice without affecting insulin sensitivity and adipose tissue inflammation

FASEB BioAdvances
2021 | Journal article
DOI: 10.1096/fba.2020-00081
EID:

2-s2.0-85104458532

Part of ISSN: 25739832
Contributors: Mazzoli, A.; Sardi, C.; Breasson, L.; Theilig, F.; Becattini, B.; Solinas, G.
Source: Self-asserted source
Barbara Becattini via Scopus - Elsevier

PI3Kγ promotes obesity-associated hepatocellular carcinoma by regulating metabolism and inflammation

JHEP Reports
2021 | Journal article
DOI: 10.1016/j.jhepr.2021.100359
EID:

2-s2.0-85122779139

Part of ISSN: 25895559
Contributors: Becattini, B.; Breasson, L.; Sardi, C.; Zani, F.; Solinas, G.
Source: Self-asserted source
Barbara Becattini via Scopus - Elsevier

Hyperinsulinemia and insulin resistance in the obese may develop as part of a homeostatic response to elevated free fatty acids: A mechanistic case-control and a population-based cohort study

EBioMedicine
2021-03 | Journal article
DOI: 10.1016/j.ebiom.2021.103264
Contributors: Emanuel Fryk; Josefin Olausson; Karin Mossberg; Lena Strindberg; Martin Schmelz; Helén Brogren; Li-Ming Gan; Silvano Piazza; Alessandro Provenzani; Barbara Becattini et al.
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Insulin signaling and glucose metabolism in different hepatoma cell lines deviate from hepatocyte physiology toward a convergent aberrant phenotype

Scientific Reports
2020 | Journal article
DOI: 10.1038/s41598-020-68721-9
EID:

2-s2.0-85088321212

Part of ISSN: 20452322
Contributors: Molinaro, A.; Becattini, B.; Solinas, G.
Source: Self-asserted source
Barbara Becattini via Scopus - Elsevier

Insulin-Driven PI3K-AKT Signaling in the Hepatocyte Is Mediated by Redundant PI3Kα and PI3Kβ Activities and Is Promoted by RAS.

Cell metabolism
2019-04-11 | Journal article
DOI: 10.1016/j.cmet.2019.03.010
PMID: 30982732
Source: Self-asserted source
Barbara Becattini
grade
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The role of PI3Kγ in metabolism and macrophage activation.

Oncotarget
2017-10-25 | Journal article
DOI: 10.18632/oncotarget.22068
PMID: 29290924
PMC: PMC5739709
Source: Self-asserted source
Barbara Becattini
grade
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PI3Kγ ablation does not promote diabetes in db/db mice, but improves insulin sensitivity and reduces pancreatic β-cell apoptosis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
2017-09-13 | Journal article
DOI: 10.1096/fj.201700372rr
PMID: 28904022
Source: Self-asserted source
Barbara Becattini
grade
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PI3Kγ activity in leukocytes promotes adipose tissue inflammation and early-onset insulin resistance during obesity

Science Signaling
2017-07-18 | Journal article
DOI: 10.1126/scisignal.aaf2969
Contributors: Ludovic Breasson; Barbara Becattini; Claudia Sardi; Angela Molinaro; Fabio Zani; Romina Marone; Fabrizio Botindari; Mélanie Bousquenaud; Curzio Ruegg; Matthias P. Wymann et al.
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JNK at the crossroad of obesity, insulin resistance, and cell stress response.

2017-02 | Journal article
DOI: 10.1016/j.molmet.2016.12.001
PMID: 28180059
PMC: PMC5279903
Contributors: Solinas G; Becattini B
Source: Self-asserted source
Barbara Becattini via Europe PubMed Central
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JNK1 ablation in mice confers long-term metabolic protection from diet-induced obesity at the cost of moderate skin oxidative damage.

2016-09 | Journal article
DOI: 10.1096/fj.201600393r
PMID: 27230858
Contributors: Becattini B; Zani F; Breasson L; Sardi C; D'Agostino VG; Choo MK; Provenzani A; Park JM; Solinas G
Source: Self-asserted source
Barbara Becattini via Europe PubMed Central
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PER2 promotes glucose storage to liver glycogen during feeding and acute fasting by inducing Gys2 PTG and G L expression.

2013 | Journal article
DOI: 10.1016/j.molmet.2013.06.006
PMID: 24049741
PMC: PMC3773838
Contributors: Zani F; Breasson L; Becattini B; Vukolic A; Montani JP; Albrecht U; Provenzani A; Ripperger JA; Solinas G
Source: Self-asserted source
Barbara Becattini via Europe PubMed Central
grade
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PI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance.

2011-10 | Journal article
DOI: 10.1073/pnas.1106698108
PMID: 21949398
PMC: PMC3198370
Contributors: Becattini B; Marone R; Zani F; Arsenijevic D; Seydoux J; Montani JP; Dulloo AG; Thorens B; Preitner F; Wymann MP et al.
Source: Self-asserted source
Barbara Becattini via Europe PubMed Central
grade
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Bid-induced release of AIF from mitochondria causes immediate neuronal cell death.

2008-10 | Journal article
DOI: 10.1038/cdd.2008.78
PMID: 18535584
PMC: PMC2862690
Contributors: Landshamer S; Hoehn M; Barth N; Duvezin-Caubet S; Schwake G; Tobaben S; Kazhdan I; Becattini B; Zahler S; Vollmar A et al.
Source: Self-asserted source
Barbara Becattini via Europe PubMed Central
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Identification of a new JNK inhibitor targeting the JNK-JIP interaction site.

2008-10 | Journal article
DOI: 10.1073/pnas.0805677105
PMID: 18922779
PMC: PMC2567907
Contributors: Stebbins JL; De SK; Machleidt T; Becattini B; Vazquez J; Kuntzen C; Chen LH; Cellitti JF; Riel-Mehan M; Emdadi A et al.
Source: Self-asserted source
Barbara Becattini via Europe PubMed Central
grade
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Boron: A key element in radical reactions

Pure and Applied Chemistry
2007 | Conference paper
DOI: 10.1351/pac200779020223
EID:

2-s2.0-33846936245

Part of ISSN: 00334545
Contributors: Renaud, P.; Beauseigneur, A.; Brecht-Forster, A.; Becattini, B.; Darmency, V.; Kandhasamy, S.; Montermini, F.; Ollivier, C.; Panchaud, P.; Pozzi, D. et al.
Source: Self-asserted source
Barbara Becattini via Scopus - Elsevier

Structure-activity relationships by interligand NOE-based design and synthesis of antiapoptotic compounds targeting Bid.

2006-08 | Journal article
DOI: 10.1073/pnas.0603460103
PMID: 16891420
PMC: PMC1567925
Contributors: Becattini B; Culmsee C; Leone M; Zhai D; Zhang X; Crowell KJ; Rega MF; Landshamer S; Reed JC; Plesnila N et al.
Source: Self-asserted source
Barbara Becattini via Europe PubMed Central
grade
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SAR by ILOEs: an NMR-based approach to reverse chemical genetics.

2006-03 | Journal article
DOI: 10.1002/chem.200500636
PMID: 16121405
Contributors: Becattini B; Pellecchia M
Source: Self-asserted source
Barbara Becattini via Europe PubMed Central
grade
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Erratum: Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia (Journal of Neuroscience (November 2, 2005) (10262-10272))

Journal of Neuroscience
2005 | Journal article
EID:

2-s2.0-27944503825

Part of ISSN: 02706474 02706474
Contributors: Culmsee, C.; Zhu, C.; Landshamer, S.; Becattini, B.; Wagner, E.; Pellechia, M.; Blomgren, K.; Plesnila, N.
Source: Self-asserted source
Barbara Becattini via Scopus - Elsevier

Thiophenol-mediated 1,5-hydrogen atom abstraction: Easy access to mono- and bicyclic compounds

Advanced Synthesis and Catalysis
2005 | Journal article
DOI: 10.1002/adsc.200505211
EID:

2-s2.0-27544469847

Part of ISSN: 16154150
Contributors: Beaufils, F.; Dénès, F.; Becattini, B.; Renaud, P.; Schenk, K.
Source: Self-asserted source
Barbara Becattini via Scopus - Elsevier

Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia.

2005-11 | Journal article
DOI: 10.1523/jneurosci.2818-05.2005
PMID: 16267234
Contributors: Culmsee C; Zhu C; Landshamer S; Becattini B; Wagner E; Pellecchia M; Blomgren K; Plesnila N
Source: Self-asserted source
Barbara Becattini via Europe PubMed Central
grade
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Efficient synthetic inhibitors of anthrax lethal factor.

2005-07 | Journal article
DOI: 10.1073/pnas.0502733102
PMID: 15983377
PMC: PMC1160517
Contributors: Forino M; Johnson S; Wong TY; Rozanov DV; Savinov AY; Li W; Fattorusso R; Becattini B; Orry AJ; Jung D et al.
Source: Self-asserted source
Barbara Becattini via Europe PubMed Central
grade
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Yersinia phosphatase induces mitochondrially dependent apoptosis of T cells.

2005-03 | Journal article
DOI: 10.1074/jbc.m408829200
PMID: 15632192
Contributors: Bruckner S; Rhamouni S; Tautz L; Denault JB; Alonso A; Becattini B; Salvesen GS; Mustelin T
Source: Self-asserted source
Barbara Becattini via Europe PubMed Central
grade
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NMR-based techniques in the hit identification and optimisation processes.

2004-12 | Journal article
DOI: 10.1517/14728222.8.6.597
PMID: 15584865
Contributors: Pellecchia M; Becattini B; Crowell KJ; Fattorusso R; Forino M; Fragai M; Jung D; Mustelin T; Tautz L
Source: Self-asserted source
Barbara Becattini via Europe PubMed Central
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Targeting apoptosis via chemical design: inhibition of bid-induced cell death by small organic molecules.

2004-08 | Journal article
DOI: 10.1016/j.chembiol.2004.05.022
PMID: 15324812
Contributors: Becattini B; Sareth S; Zhai D; Crowell KJ; Leone M; Reed JC; Pellecchia M
Source: Self-asserted source
Barbara Becattini via Europe PubMed Central
grade
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Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-X(L).

2004-03 | Journal article
DOI: 10.1016/j.chembiol.2004.02.020
PMID: 15123268
Contributors: Becattini B; Kitada S; Leone M; Monosov E; Chandler S; Zhai D; Kipps TJ; Reed JC; Pellecchia M
Source: Self-asserted source
Barbara Becattini via Europe PubMed Central
grade
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B-Alkylcatecholboranes as a Source of Radicals for Efficient Conjugate Additions and Allylations

Synthesis
2003 | Journal article
DOI: 10.1055/s-2003-42430
EID:

2-s2.0-0346122766

Part of ISSN: 00397881
Contributors: Schaffner, A.-P.; Becattini, B.; Ollivier, C.; Weber, V.; Renaud, P.
Source: Self-asserted source
Barbara Becattini via Scopus - Elsevier

Organoboranes mediated radical cyclizations

Synlett
2003 | Journal article
DOI: 10.1055/s-2003-40835
EID:

2-s2.0-0041568537

Part of ISSN: 09365214
Contributors: Becattini, B.; Ollivier, C.; Renaud, P.
Source: Self-asserted source
Barbara Becattini via Scopus - Elsevier

Carbohydrate-based peptido memetics. Synthesis of two new scaffolds for combinatorial libraries.<sup>1</sup>

Journal of Carbohydrate Chemistry
2000 | Journal article
DOI: 10.1080/07328300008544108
EID:

2-s2.0-0034342217

Part of ISSN: 07328303
Contributors: Becattini, B.; Capozzi, G.; Falciani, C.; Menichetti, S.; Nativi, C.; Salvini, A.
Source: Self-asserted source
Barbara Becattini via Scopus - Elsevier

Carbohydrate-based peptido mimetics. Synthesis of two new scaffolds for combinatorial libraries.

2000 | Other
OTHER-ID:

IND22071906
Contributors: Becattini B; Capozzi G; Falciani C; Menichetti S; Nativi C; Salvini A
Source: Self-asserted source
Barbara Becattini via Europe PubMed Central
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