Personal information

Activities

Collapse all

Works (24)

TNF overexpression and dexamethasone treatment impair chondrogenesis and bone growth in an additive manner.

Scientific reports
2022-10 | Journal article
DOI: 10.1038/s41598-022-22734-8
PMID: 36307458
PMC: PMC9616891
Contributors: Zhao Y; Celvin B; Denis MC; Karagianni N; Aulin C; Zaman F; Sävendahl L
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Repurposing of Amisulpride, a known antipsychotic drug, to target synovial fibroblasts activation in arthritis

2022-08 | Preprint
DOI: 10.1101/2022.08.02.500956
PPR: PPR526889
Contributors: Papadopoulou D; Roumelioti F; Tzaferis C; Chouvardas P; Pedersen A; Charalampous F; Christodoulou-Vafeiadou E; Ntari L; Karagianni N; Denis M et al.
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

miR-221/222 drive synovial fibroblast expansion and pathogenesis of TNF-mediated arthritis

2022-07 | Preprint
DOI: 10.1101/2022.07.22.500939
PPR: PPR521569
Contributors: Roumelioti F; Tzaferis C; Konstantopoulos D; Papadopoulou D; Prados A; Sakkou M; Liakos A; Chouvardas P; Meletakos T; Pandis Y et al.
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

TNFα induces endothelial dysfunction in rheumatoid arthritis via LOX-1 and arginase 2: reversal by monoclonal TNFα antibodies.

Cardiovascular research
2022-01 | Journal article
DOI: 10.1093/cvr/cvab005
PMID: 33483748
Contributors: Akhmedov A; Crucet M; Simic B; Kraler S; Bonetti NR; Ospelt C; Distler O; Ciurea A; Liberale L; Jauhiainen M et al.
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment.

Journal of translational medicine
2021-04 | Journal article
DOI: 10.1186/s12967-021-02764-y
PMID: 33892739
PMC: PMC8063445
Contributors: Ntari L; Nikolaou C; Kranidioti K; Papadopoulou D; Christodoulou-Vafeiadou E; Chouvardas P; Meier F; Geka C; Denis MC; Karagianni N et al.
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment

2020-11 | Preprint
DOI: 10.21203/rs.3.rs-108559/v1
PPR: PPR241255
Contributors: Ntari L; Nikolaou C; Kranidioti K; Papadopoulou D; Chouvardas P; Meier F; Geka C; Denis MC; Karagianni N; Kollias G
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis.

Arthritis research & therapy
2020-10 | Journal article
DOI: 10.1186/s13075-020-02327-4
PMID: 33023659
PMC: PMC7542121
Contributors: Christodoulou-Vafeiadou E; Geka C; Ntari L; Kranidioti K; Argyropoulou E; Meier F; Armaka M; Mourouzis I; Pantos C; Rouchota M et al.
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

An integrative transcriptome analysis framework for drug efficacy and similarity reveals drug-specific signatures of anti-TNF treatment in a mouse model of inflammatory polyarthritis.

PLoS computational biology
2019-05 | Journal article
DOI: 10.1371/journal.pcbi.1006933
PMID: 31071076
PMC: PMC6508611
Contributors: Karagianni N; Kranidioti K; Fikas N; Tsochatzidou M; Chouvardas P; Denis MC; Kollias G; Nikolaou C
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Mesenchymal TNFR2 promotes the development of polyarthritis and comorbid heart valve stenosis.

JCI insight
2018-04 | Journal article
DOI: 10.1172/jci.insight.98864
PMID: 29618659
PMC: PMC5928856
Contributors: Sakkou M; Chouvardas P; Ntari L; Prados A; Moreth K; Fuchs H; Gailus-Durner V; Hrabe de Angelis M; Denis MC; Karagianni N et al.
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Comorbid TNF-mediated heart valve disease and chronic polyarthritis share common mesenchymal cell-mediated aetiopathogenesis.

Annals of the rheumatic diseases
2018-02 | Journal article
DOI: 10.1136/annrheumdis-2017-212597
PMID: 29475857
PMC: PMC5965351
Contributors: Ntari L; Sakkou M; Chouvardas P; Mourouzis I; Prados A; Denis MC; Karagianni N; Pantos C; Kollias G
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression.

Scientific reports
2017-05 | Journal article
DOI: 10.1038/s41598-017-02581-8
PMID: 28546545
PMC: PMC5445072
Contributors: Kaklamanos A; Rozman J; Roulis M; Karagianni N; Armaka M; Wu M; Brachthäuser L; Calzada-Wack J; Horsch M; Beckers J et al.
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Targeted Metabolic Profiling of the Tg197 Mouse Model Reveals Itaconic Acid as a Marker of Rheumatoid Arthritis.

Journal of proteome research
2016-10 | Journal article
DOI: 10.1021/acs.jproteome.6b00654
PMID: 27704840
Contributors: Michopoulos F; Karagianni N; Whalley NM; Firth MA; Nikolaou C; Wilson ID; Critchlow SE; Kollias G; Theodoridis GA
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Improved topical delivery of tacrolimus: A novel composite hydrogel formulation for the treatment of psoriasis.

Journal of controlled release : official journal of the Controlled Release Society
2016-09 | Journal article
DOI: 10.1016/j.jconrel.2016.09.007
PMID: 27639683
Contributors: Gabriel D; Mugnier T; Courthion H; Kranidioti K; Karagianni N; Denis MC; Lapteva M; Kalia Y; Möller M; Gurny R
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Frailty in mouse ageing: A conceptual approach.

Mechanisms of ageing and development
2016-07 | Journal article
DOI: 10.1016/j.mad.2016.07.004
PMID: 27443148
Contributors: von Zglinicki T; Varela Nieto I; Brites D; Karagianni N; Ortolano S; Georgopoulos S; Cardoso AL; Novella S; Lepperdinger G; Trendelenburg AU et al.
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis.

Proceedings of the National Academy of Sciences of the United States of America
2014-10 | Journal article
DOI: 10.1073/pnas.1415762111
PMID: 25316791
PMC: PMC4217397
Contributors: Roulis M; Nikolaou C; Kotsaki E; Kaffe E; Karagianni N; Koliaraki V; Salpea K; Ragoussis J; Aidinis V; Martini E et al.
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Tumor necrosis factor receptor signaling in keratinocytes triggers interleukin-24-dependent psoriasis-like skin inflammation in mice.

Immunity
2013-11 | Journal article
DOI: 10.1016/j.immuni.2013.10.009
PMID: 24211183
Contributors: Kumari S; Bonnet MC; Ulvmar MH; Wolk K; Karagianni N; Witte E; Uthoff-Hachenberg C; Renauld JC; Kollias G; Toftgard R et al.
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium.

The Journal of clinical investigation
2013-05 | Journal article
DOI: 10.1172/jci65624
PMID: 23676465
PMC: PMC3668821
Contributors: Van Hauwermeiren F; Armaka M; Karagianni N; Kranidioti K; Vandenbroucke RE; Vandenbroucke RE; Loges S; Van Roy M; Staelens J; Puimège L et al.
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via predictions using the human tumour necrosis factor transgenic mouse model.

Annals of the rheumatic diseases
2012-05 | Journal article
DOI: 10.1136/annrheumdis-2011-200803
PMID: 22562984
Contributors: Pandis I; Ospelt C; Karagianni N; Denis MC; Reczko M; Camps C; Hatzigeorgiou AG; Ragoussis J; Gay S; Kollias G
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Myeloid TAKI [corrected] acts as a negative regulator of the LPS response and mediates resistance to endotoxemia.

PloS one
2012-02 | Journal article
DOI: 10.1371/journal.pone.0031550
PMID: 22348103
PMC: PMC3279403
Contributors: Eftychi C; Karagianni N; Alexiou M; Apostolaki M; Kollias G
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Association of microRNA-221/222 and -323-3p with rheumatoid arthritis via predictions using the human TNF transgenic mouse model

Arthritis research & therapy
2012-01 | Journal article
DOI: 10.1186/ar3660
PMC: PMC3332506
Contributors: Pandis I; Ospelt C; Karagianni N; Denis M; Reczko M; Camps C; Hatzigeorgiou A; Ragoussis J; Gay S; Kollias G
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Novel adenomatous polyposis coli gene promoter is located 40 kb upstream of the initiating methionine.

Genomics
2005-02 | Journal article
DOI: 10.1016/j.ygeno.2004.09.005
PMID: 15676281
Contributors: Karagianni N; Ly MC; Psarras S; Chlichlia K; Schirrmacher V; Gounari F; Khazaie K
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

Gene transfer and genetic modification of embryonic stem cells by Cre- and Cre-PR-expressing MESV-based retroviral vectors.

The journal of gene medicine
2004-01 | Journal article
DOI: 10.1002/jgm.442
PMID: 14716675
Contributors: Psarras S; Karagianni N; Kellendonk C; Tronche F; Cosset FL; Stocking C; Schirrmacher V; Boehmer Hv Hv; Khazaie K
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

The mouse filensin gene: structure and evolutionary relation to other intermediate filament genes.

FEBS letters
1997-08 | Journal article
DOI: 10.1016/s0014-5793(97)00937-x
PMID: 9280315
Contributors: Gounari F; Karagianni N; Mincheva A; Lichter P; Georgatos SD; Schirrmacher V
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central

The c-fos serum response element (SRE) confers negative response to glucocorticoids.

Oncogene
1994-08 | Journal article
PMID: 8036015
Contributors: Karagianni N; Tsawdaroglou N
Source: Self-asserted source
Niki Karagianni via Europe PubMed Central
How many people are using ORCID?