Personal information

computational pathology, biomarker discovery, bioinformatics, pattern recognition, machine learning, biostatistics, precision medicine
Czech Republic, Switzerland

Activities

Employment (5)

Masaryk University: Brno, CZ

2017-01-01 to present | associate professor (RECETOX)
Employment
Source: Self-asserted source
Vlad Popovici

Masaryk University: Brno, CZ

2013-03-01 to present | assistant professor (Institute of Biostatistics and Analyses)
Employment
Source: Self-asserted source
Vlad Popovici

Swiss Institute of Bioinformatics: Lausanne, VD, CH

2006-04-01 to 2013-02-28
Employment
Source: Self-asserted source
Vlad Popovici

Ecole Polytechnique Federale de Lausanne: Lausanne, VD, CH

2000-04-01 to 2006-03-31
Employment
Source: Self-asserted source
Vlad Popovici

Tampere University of Technology: Tampere, FI

1999-07-01 to 2000-03-31
Employment
Source: Self-asserted source
Vlad Popovici

Education and qualifications (1)

Ecole Polytechnique Federale de Lausanne: Lausanne, VD, CH

2000 to 2004 | PhD
Education
Source: Self-asserted source
Vlad Popovici

Funding (2)

Clinical implications of intra-tumour heterogeneity in colon cancer

2019-01-05 to 2022-12-31 | Grant
Ministry of Health (Prague, CZ)
GRANT_NUMBER: NV19-03-00298
Source: Self-asserted source
Vlad Popovici via DimensionsWizard

Molecular portraits of major morphological components of colon tumors

2019-01-01 to 2022-12-31 | Grant
Czech Science Foundation (Prague, CZ)
GRANT_NUMBER: GA19-08646S
Source: Self-asserted source
Vlad Popovici via DimensionsWizard

Works (50 of 87)

Items per page:
Page 1 of 2

A quantitative tumor–wide analysis of morphological heterogeneity of colorectal adenocarcinoma

2024-04-14 | Preprint
Contributors: Mihnea P. Dragomir; Vlad Popovici; Simon Schallenberg; Martina Čarnogurská; David Horst; Rudolf Nenutil; Fred Bosman; Eva Budinská
Source: check_circle
Crossref

Molecular portraits of morphotypes - large supplemental tables

Source: Self-asserted source
Vlad Popovici via BASE - Bielefeld Academic Search Engine

Molecular portraits of colorectal cancer morphological regions

eLife
2023-11-13 | Journal article | Author
Part of ISSN: 2050-084X
Contributors: Eva Budinská; Martina Hrivňáková; Tina Catela Ivkovic; Marie Madrzyk; Rudolf Nenutil; Beatrix Bencsiková; Dagmar Al Tukmachi; Michaela Ručková; Lenka Zdražilová Dubská; Ondřej Slabý et al.
Source: Self-asserted source
Vlad Popovici

IntOMICS: A Bayesian Framework for Reconstructing Regulatory Networks Using Multi-Omics Data

Journal of Computational Biology
2023-05-01 | Journal article
Part of ISSN: 1557-8666
Contributors: Anna Pačínková; Vlad Popovici
Source: Self-asserted source
Vlad Popovici

Using empirical biological knowledge to infer regulatory networks from multi-omics data

BMC Bioinformatics
2022-08-22 | Journal article
Part of ISSN: 1471-2105
Contributors: Anna Pačínková; Vlad Popovici
Source: Self-asserted source
Vlad Popovici

Colorectal Tumour Mucosa Microbiome Is Enriched in Oral Pathogens and Defines Three Subtypes That Correlate with Markers of Tumour Progression.

Cancers
2021-09-25 | Journal article
Source: Self-asserted source
Vlad Popovici

An Explorative Analysis of ABCG2/TOP-1 mRNA Expression as a Biomarker Test for FOLFIRI Treatment in Stage III Colon Cancer Patients: Results from Retrospective Analyses of the PETACC-3 Trial

Cancers
2020-04-15 | Journal article
Contributors: Jan Stenvang; Eva Budinská; Eric van Cutsem; Fred Bosman; Vlad Popovici; Nils Brünner
Source: check_circle
Crossref

Stool sampling and DNA isolation kits affect DNA quality and bacterial composition following 16S rRNA gene sequencing using MiSeq Illumina platform

Scientific Reports
2019-12 | Journal article
Source: Self-asserted source
Vlad Popovici

Characterization of molecular scores and gene expression signatures in primary breast cancer, local recurrences and brain metastases.

BMC cancer
2019-06-07 | Journal article
Source: Self-asserted source
Vlad Popovici

Cross-platform Data Analysis Reveals a Generic Gene Expression Signature for Microsatellite Instability in Colorectal Cancer.

BioMed Research International
2019-03-17 | Journal article
Source: Self-asserted source
Vlad Popovici

High resolution images for 'Identification of "BRAF-positive" cases based on whole-slide image analysis'

Source: Self-asserted source
Vlad Popovici via BASE - Bielefeld Academic Search Engine

Identification of “BRAF-Positive” Cases Based on Whole-Slide Image Analysis

BioMed Research International
2017 | Journal article
Contributors: Vlad Popovici; Aleš Křenek; Eva Budinská
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Image-based surrogate biomarkers for molecular subtypes of colorectal cancer

Bioinformatics
2017 | Journal article
WOSUID:

WOS:000404054700013

Contributors: Popovici, Vlad; Budinska, Eva; Dusek, Ladislav; Kozubek, Michal; Bosman, Fred
Source: Self-asserted source
Vlad Popovici via ResearcherID

Experiments in Molecular Subtype Recognition Based on Histopathology Images

2016 Ieee 13th International Symposium on Biomedical Imaging (Isbi)
2016 | Book chapter
WOSUID:

WOS:000386377400276

Contributors: Budinska, Eva; Bosman, Fred; Popovici, Vlad; IEEE
Source: Self-asserted source
Vlad Popovici via ResearcherID

Joint analysis of histopathology image features and gene expression in breast cancer

Bmc Bioinformatics
2016 | Journal article
WOSUID:

WOS:000375849000001

Contributors: Popovici, Vlad; Budinska, Eva; Capkova, Lenka; Schwarz, Daniel; Dusek, Ladislav; Feit, Josef; Jaggi, Rolf
Source: Self-asserted source
Vlad Popovici via ResearcherID

MErCuRIC1: A phase 1a study of MEK1/2 inhibitor PD-0325901 with cMET inhibitor crizotinib in patients with advanced solid tumours

Annals of Oncology
2016 | Journal article
WOSUID:

WOS:000393912500534

Contributors: Wilson, R.; Middleton, M. R.; Houlden, J.; Van Schaeybroeck, S.; Rolfo, C. D.; Elez, E.; Taieb, J.; Andre, T.; Bardelli, A.; Laurent-Puig, P. et al.
Source: Self-asserted source
Vlad Popovici via ResearcherID

Validation of a MEK/MET-specific NGS panel for early phase trial interrogation

Cancer Research
2016 | Journal article
WOSUID:

WOS:000389940602208

Contributors: Maxwell, Perry; Del Favero, Jurgen; Fuchs, Marc-Aurel; Tabernero, Josep; Maughan, Tim; Middleton, Mark; Addams, Richard; Rolfo, Christian; Hennessey, Brian; Laurent-Puig, Pierre et al.
Source: Self-asserted source
Vlad Popovici via ResearcherID

Towards the identification of tissue based proxy biomarkers

AMIA Joint Summit on Translational Science
2016-03 | Conference paper
Source: Self-asserted source
Vlad Popovici

Gene expression-guided selection of histopathology image features

2015 IEEE 15th International Conference on Bioinformatics and Bioengineering, BIBE 2015
2015 | Conference paper
EID:

2-s2.0-84962866400

Contributors: Budinská, E.; Čápková, L.; Schwarz, D.; Dušek, L.; Jaggi, R.; Feit, J.; Popovici, V.
Source: Self-asserted source
Vlad Popovici via Scopus - Elsevier

MErCuRIC1: A Phase I study of MEK1/2 inhibitor PD-0325901 with cMET inhibitor crizotinib in RASMT and RASWT (with aberrant c-MET) metastatic colorectal cancer (mCRC) patients.

Journal of Clinical Oncology
2015 | Journal article
WOSUID:

WOS:000358036904735

Contributors: Van Schaeybroeck, Sandra; Rolfo, Christian D.; Elez, Elena; Kelly, Stephen; Houlden, Jennifer; Collins, Linda; Love, Sharon; Andre, Thierry; Lawler, Mark; Di Nicolantonio, Federica et al.
Source: Self-asserted source
Vlad Popovici via ResearcherID

Hierarchical contexts from breast cancer histopathology images

4th Intl. Conf. on Computational and Mathematical Biomedical Engineering (CMBE)
2015-06-29 | Conference paper
Source: Self-asserted source
Vlad Popovici

Distal and proximal colon cancers differ in terms of molecular, pathological, and clinical features

Annals of Oncology
2014 | Journal article
WOSUID:

WOS:000343045500017

Contributors: Missiaglia, E.; Jacobs, B.; D'Ario, G.; Di Narzo, A. F.; Soneson, C.; Budinska, E.; Popovici, V.; Vecchione, L.; Gerster, S.; Yan, P. et al.
Source: Self-asserted source
Vlad Popovici via ResearcherID
grade
Preferred source (of 2)‎

Test of Four Colon Cancer Risk-Scores in Formalin Fixed Paraffin Embedded Microarray Gene Expression Data

Jnci-Journal of the National Cancer Institute
2014 | Journal article
WOSUID:

WOS:000343038200004

Contributors: Di Narzo, Antonio F.; Tejpar, Sabine; Rossi, Simona; Yan, Pu; Popovici, Vlad; Wirapati, Pratyaksha; Budinska, Eva; Xie, Tao; Estrella, Heather; Pavlicek, Adam et al.
Source: Self-asserted source
Vlad Popovici via ResearcherID

Test of Four Colon Cancer Risk-Scores in Formalin Fixed Paraffin Embedded Microarray Gene Expression Data

Jnci-Journal of the National Cancer Institute
2014 | Journal article
Contributors: Di Narzo, Antonio F.; Tejpar, Sabine; Rossi, Simona; Yan, Pu; Popovici, Vlad; Wirapati, Pratyaksha; Budinska, Eva; Xie, Tao; Estrella, Heather; Pavlicek, Adam et al.
Source: Self-asserted source
Vlad Popovici via ResearcherID

Test of four colon cancer risk-scores in formalin fixed paraffin embedded microarray gene expression data.

Journal of the National Cancer Institute
2014 | Journal article
EID:

2-s2.0-84908577174

Contributors: Di Narzo, A.F.; Tejpar, S.; Rossi, S.; Yan, P.; Popovici, V.; Wirapati, P.; Budinska, E.; Xie, T.; Estrella, H.; Pavlicek, A. et al.
Source: Self-asserted source
Vlad Popovici via Scopus - Elsevier

BRAF and KRAS mutations as additional risk factors in the context of clinical parameters of patients with colorectal cancer.

Journal of Clinical Oncology
2013 | Journal article
WOSUID:

WOS:000335419601258

Contributors: Popovici, Vlad Calin; Budinska, Eva; Roth, Arnaud; Bosman, Fred; Tejpar, Sabine; Delorenzi, Mauro
Source: Self-asserted source
Vlad Popovici via ResearcherID

Connecting gene expression subtypes of colorectal cancer (CRC) with cell lines and drug resistance.

Journal of Clinical Oncology
2013 | Journal article
WOSUID:

WOS:000335419603513

Contributors: Budinska, Eva; Wilding, Jenny; Popovici, Vlad Calin; Missiaglia, Edoardo; Roth, Arnaud; Bosman, Fred; Delorenzi, Mauro; Bodmer, Walter; Tejpar, Sabine
Source: Self-asserted source
Vlad Popovici via ResearcherID

Context-dependent interpretation of the prognostic value of BRAF and KRAS mutations in colorectal cancer

Bmc Cancer
2013 | Journal article
WOSUID:

WOS:000325080000001

Contributors: Popovici, Vlad; Budinska, Eva; Bosman, Fred T.; Tejpar, Sabine; Roth, Arnaud D.; Delorenzi, Mauro
Source: Self-asserted source
Vlad Popovici via ResearcherID
grade
Preferred source (of 2)‎

Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer

Journal of Pathology
2013 | Journal article
WOSUID:

WOS:000322761500008

Contributors: Budinska, Eva; Popovici, Vlad; Tejpar, Sabine; D'Ario, Giovanni; Lapique, Nicolas; Sikora, Katarzyna Otylia; Di Narzo, Antonio Fabio; Yan, Pu; Hodgson, John Graeme; Weinrich, Scott et al.
Source: Self-asserted source
Vlad Popovici via ResearcherID
grade
Preferred source (of 2)‎

Identification of synthetic lethal interactions with the BRAF oncogene in colorectal cancer

Journal of Clinical Oncology
2013 | Journal article
WOSUID:

WOS:000333679000396

Contributors: Vecchione, Loredana; Gambino, Valentina; d'Ario, Giovanni; Tian, Sun; Simon, Iris; Popovici, Vlad Calin; Delorenzi, Mauro; Bernards, Rene; Tejpar, Sabine
Source: Self-asserted source
Vlad Popovici via ResearcherID

The EurOPDX consortium: Sharing patient tumor-derived xenografts for collaborative multicentric preclinical trials.

Molecular Cancer Therapeutics
2013 | Journal article
WOSUID:

WOS:000209496800008

Contributors: Vinolo, Emilie; Marangoni, Elisabetta; Serra, Violeta; Amant, Frederic; Bertotti, Andrea; Biankin, Andrew V.; Borresen-Dale, Anne-Lise; Bruna, Alejandra; Budinska, Eva; Byrne, Annette et al.
Source: Self-asserted source
Vlad Popovici via ResearcherID

A Comprehensive Characterization of Genome-Wide Copy Number Aberrations in Colorectal Cancer Reveals Novel Oncogenes and Patterns of Alterations

Plos One
2012 | Journal article
WOSUID:

WOS:000307045600049

Contributors: Xie, Tao; d' Ario, Giovanni; Lamb, John R.; Martin, Eric; Wang, Kai; Tejpar, Sabine; Delorenzi, Mauro; Bosman, Fred T.; Roth, Arnaud D.; Yan, Pu et al.
Source: Self-asserted source
Vlad Popovici via ResearcherID
grade
Preferred source (of 2)‎

A robust genomic signature for the detection of colorectal cancer patients with microsatellite instability phenotype and high mutation frequency

Journal of Pathology
2012 | Journal article
WOSUID:

WOS:000313949800016

Contributors: Tian, Sun; Roepman, Paul; Popovici, Vlad; Michaut, Magali; Majewski, Ian; Salazar, Ramon; Santos, Cristina; Rosenberg, Robert; Nitsche, Ulrich; Mesker, Wilma E. et al.
Source: Self-asserted source
Vlad Popovici via ResearcherID
grade
Preferred source (of 2)‎

Identification and validation of gene expression subtypes in a large set of colorectal cancer samples.

Journal of Clinical Oncology
2012 | Journal article
WOSUID:

WOS:000318009801829

Contributors: Budinska, Eva; Popovici, Vlad Calin; Sikora, Katarzyna Otylia; Lapique, Nicolas; Tejpar, Sabine; Hodgson, John Graeme; Weinrich, Scott; Roth, Arnaud; Bosman, Fred; Delorenzi, Mauro
Source: Self-asserted source
Vlad Popovici via ResearcherID

Identification of a Poor-Prognosis BRAF-Mutant-Like Population of Patients With Colon Cancer

Journal of Clinical Oncology
2012 | Journal article
WOSUID:

WOS:000303756500012

Contributors: Popovici, Vlad; Budinska, Eva; Tejpar, Sabine; Weinrich, Scott; Estrella, Heather; Hodgson, Graeme; Van Cutsem, Eric; Xie, Tao; Bosman, Fred T.; Roth, Arnaud D. et al.
Source: Self-asserted source
Vlad Popovici via ResearcherID
grade
Preferred source (of 2)‎

Identification of the BRAF-like Signature Predictive of Response Towards MEK Inhibition by Pimasertib (MSC1936369B) in Colorectal Cancer Cell Lines

European Journal of Cancer
2012 | Journal article
WOSUID:

WOS:000312763000426

Contributors: De Vriendt, V.; Sikora, K.; Van den Bosch, B.; Popovici, V.; Delorenzi, M.; Tejpar, S.
Source: Self-asserted source
Vlad Popovici via ResearcherID

Molecular and clinicopathologic evidence of heterogeneity in KRAS-mutant colon cancers

Journal of Clinical Oncology
2012 | Journal article
Part of ISSN: 0732-183X
Contributors: Bosman, Fred; Budinska, Eva; Delorenzi, Mauro; Di Narzo, Antonio Fabio; Hodgson, John Graeme; Popovici, Vlad Calin; Roth, Arnaud; Tejpar, Sabine; d'Ario, Giovanni
Source: Self-asserted source
Vlad Popovici via ResearcherID

Molecular and clinicopathologic evidence of heterogeneity in KRAS-mutant colon cancers

Journal of Clinical Oncology
2012 | Journal article
WOSUID:

WOS:000318009804820

Contributors: Popovici, Vlad Calin; Budinska, Eva; Tejpar, Sabine; d'Ario, Giovanni; Di Narzo, Antonio Fabio; Hodgson, John Graeme; Roth, Arnaud; Bosman, Fred; Delorenzi, Mauro
Source: Self-asserted source
Vlad Popovici via ResearcherID

A BRAF-mutated gene expression signature identifies BRAF wild type colon cancer patients with poor prognosis

Cancer Research
2011 | Journal article
WOSUID:

WOS:000209701404375

Contributors: Popovici, Vlad; Budinska, Eva; Tejpar, Sabine; Roth, Arnaud; Bosman, Fredrik; Weinrich, Scott; Hodgson, Graeme; Delorenzi, Mauro
Source: Self-asserted source
Vlad Popovici via ResearcherID

Rgtsp: a generalized top scoring pairs package for class prediction

Bioinformatics
2011 | Journal article
WOSUID:

WOS:000291261300032

Contributors: Popovici, Vlad; Budinska, Eva; Delorenzi, Mauro
Source: Self-asserted source
Vlad Popovici via ResearcherID
grade
Preferred source (of 2)‎

Molecular classes in CRC; Characterization of MSI by expression profiling in the translational study of the PETACC 3-FORTC 40993-SAKK 60-00 trial

Journal of Clinical Oncology
2010 | Journal article
WOSUID:

WOS:000208852003409

Contributors: Delorenzi, M.; Budinska, E.; Popovici, V.; Estrella, H.; Pavlicek, A.; Yan, P.; Weinrich, S.; Bosman, F.; Tejpar, S.; Roth, A.
Source: Self-asserted source
Vlad Popovici via ResearcherID

Mutant KRAS and BRAF gene expression profiles in colorectal cancer: Results of the translational study on the PETACC 3-EORTC 40993-SAKK 60-00 trial

Journal of Clinical Oncology
2010 | Journal article
WOSUID:

WOS:000208852003318

Contributors: Tejpar, S.; Popovici, V.; Delorenzi, M.; Budinska, E.; Estrella, H.; Mao, M.; Yan, P.; Weinrich, S.; Van Cutsem, E.; Roth, A.
Source: Self-asserted source
Vlad Popovici via ResearcherID

MUTANT KRAS AND BRAF GENE EXPRESSION PROFILES IN COLORECTAL CANCER: RESULTS OF THE TRANSLATIONAL STUDY ON THE PETACC 3-EORTC 40993-SAKK 60-00 TRIAL

Annals of Oncology
2010 | Journal article
WOSUID:

WOS:000280563300021

Contributors: Tejpar, S; Popovici, V; Delorenzi, M; Budinska, E; Estrella, H; Mao, M; Weinrich, S; Yan, P; Van Cutsem, E; Roth, A
Source: Self-asserted source
Vlad Popovici via ResearcherID

MUTANT KRAS AND BRAF GENE EXPRESSION PROFILES IN COLORECTAL CANCER: RESULTS OF THE TRANSLATIONAL STUDY ON THE PETACC 3-EORTC 40993-SAKK 60-00 TRIAL

Annals of Oncology
2010 | Journal article
Part of ISSN: 0923-7534
Contributors: Budinska, E; Delorenzi, M; Estrella, H; Mao, M; Popovici, V; Roth, A; Tejpar, S; Van Cutsem, E; Weinrich, S; Yan, P
Source: Self-asserted source
Vlad Popovici via ResearcherID

The MicroArray Quality Control (MAQC)-IIII study of common practices for the development and validation of microarray-based predictive models

Nature Biotechnology
2010 | Journal article
WOSUID:

WOS:000280757500023

Contributors: Shi, LM; Campbell, G; Jones, WD; Campagne, F; Wen, ZN; Walker, SJ; Su, ZQ; Chu, TM; Goodsaid, FM; Pusztai, L et al.
Source: Self-asserted source
Vlad Popovici via ResearcherID
grade
Preferred source (of 3)‎

Prognostic factors for breast cancer - clinical testing and validation from archival material

BREAST
2009 | Journal article
Part of ISSN: 0960-9776
Contributors: AEBI, S; ALTERMATT, H; ANTONOV, J; DELORENZI, M; GIOBBIE-HURDER, A; JAGGI, R; POPOVICI, V; THURLIMANN, B; VIALE, G
Source: Self-asserted source
Vlad Popovici via ResearcherID

Prognostic factors for breast cancer - clinical testing and validation from archival material

BREAST
2009 | Journal article
WOSUID:

WOS:000266149200097

Contributors: JAGGI, R; POPOVICI, V; ANTONOV, J; DELORENZI, M; GIOBBIE-HURDER, A; VIALE, G; THURLIMANN, B; ALTERMATT, H; AEBI, S
Source: Self-asserted source
Vlad Popovici via ResearcherID

Risk assessment of relapse in Swiss participants of BIG 1-98 with grade 2 early breast cancer by gene expression profiling using RNA from formalin-fixed, paraffin embedded (FFPE) tissue

CANCER RESEARCH
2009 | Journal article
WOSUID:

WOS:000262583200204

Contributors: AEBI, S; ANTONOV, J; POPOVICI, V; et al.
Source: Self-asserted source
Vlad Popovici via ResearcherID

Risk assessment of relapse in Swiss participants of BIG 1-98 with grade 2 early breast cancer by gene expression profiling using RNA from formalin-fixed, paraffin embedded (FFPE) tissue

CANCER RESEARCH
2009 | Journal article
Contributors: AEBI, S; ANTONOV, J; POPOVICI, V; et al.
Source: Self-asserted source
Vlad Popovici via ResearcherID

Mixtures of Boosted Classifiers for Frontal Face Detection

Signal, Image and Video Processing
2007 | Journal article
SOURCE-WORK-ID:

1112150452100-4

Contributors: MEYNET,JULIEN; POPOVICI,VLAD; THIRAN,JEAN-PHILIPPE
Source: Self-asserted source
Vlad Popovici via ResearcherID
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Peer review (1 review for 1 publication/grant)

Review activity for npj precision oncology. (1)