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Scopus Author ID: 56437255600
SciProfiles: 1276016

Biography

Our world is more interconnected than ever before. It stands to reason, then, that our health is connected to our food, the changing climate and our environment (animals, the places we go). In the Rhodes Lab we use a One Health approach to balance and optimise the health of humans, animals and the environment.

Within the Rhodes Lab we focus on:

- Developing laboratory methods, computational pipelines and surveillance tools for emerging fungal pathogens.
- Carrying out environmental sampling of air, soil and waterways to discover niches of fungal diversity and novel drug resistance mechanisms. By matching with clinical sampling, we can investigate the environmental-to-human transmission of pathogenic fungi.
- The impact of climate change as drivers of resistance and genetic diversity, using the human fungal pathogen Aspergillus fumigatus as a model organism.

Activities

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Employment (8)

The University of Birmingham: Birmingham, GB

Employment
Source: check_circle
University of Birmingham

University of Birmingham: Birmingham, GB

2024-12 to present | Assistant professor (School of Biosciences)
Employment
Source: Self-asserted source
Johanna Rhodes

Radboudumc: Nijmegen, NL

2022-10-01 to 2024-12 | Researcher (Medical Microbiology)
Employment
Source: Self-asserted source
Johanna Rhodes

Imperial College London: London, GB

2022-01-01 to 2022-09-30 | WT ISSF Research Fellow (MRC GIDA)
Employment
Source: Self-asserted source
Johanna Rhodes

Imperial College London: London, GB

2020-07-01 to 2021-12-31 | Research Fellow (Wellcome Trust)
Employment
Source: Self-asserted source
Johanna Rhodes

Imperial College London: London, GB

2016-11-02 to 2020-06-30 | Postdoctoral research associate (DIDE)
Employment
Source: Self-asserted source
Johanna Rhodes

Imperial College London: London, London, GB

2015-11-02 to 2016-11-01 | Early Career Research Fellow (Royal Brompton Hospital/DIDE)
Employment
Source: Self-asserted source
Johanna Rhodes

Imperial College London: London, London, GB

2012-11 to 2015-10-31 | Postdoctoral Research Associate (Department of Infectious Disease Epidemiology)
Employment
Source: Self-asserted source
Johanna Rhodes

Education and qualifications (1)

University of Warwick: Coventry, Coventry, GB

2009-10-03 to 2012-09-30 | PhD Systems Approaches to Biological Research (Systems Biology DTC)
Education
Source: Self-asserted source
Johanna Rhodes

Funding (6)

Investigating the mechanism(s) of tolerance in cystic fibrosis lungs to Aspergillus-related lung disease

2022-10 to 2024 | Grant
Pfizer UK (London, GB)
Source: Self-asserted source
Johanna Rhodes

Yeast on the brain: exploring links between fungal infections of the nervous system and Alzheimer’s Disease

2022-04 to 2023-03 | Grant
Wellcome Trust (London, GB)
Source: Self-asserted source
Johanna Rhodes

Transmission dynamics of the fungal pathogen Candida auris in a hospital setting

2016-07 to 2017-06 | Grant
Microsoft Research (WA, WA, US)
Source: Self-asserted source
Johanna Rhodes

Is fungal infection of the human brain a risk factor for Alzheimers Disease?

2016-03 to 2017-03 | Grant
Imperial College London School of Public Health (London, GB)
Source: Self-asserted source
Johanna Rhodes

Real-time surveillance of NHS cystic fibrosis patients for resistance mutations in the fungal pathogen Aspergillus fumigatus

2015-11 to 2016-11 | Grant
Wellcome Trust Institutional Strategic Support Fund (London, GB)
Source: Self-asserted source
Johanna Rhodes

What is the genetic basis of relapse infection of Cryptococcus neoformans?

2015-03 to 2016-02 | Grant
Imperial College London (London, Westminster, GB)
Source: Self-asserted source
Johanna Rhodes

Works (36)

Elevated mutation rates in multi-azole resistant Aspergillus fumigatus drive rapid evolution of antifungal resistance

Nature Communications
2024-12-16 | Journal article
DOI: 10.1038/s41467-024-54568-5
Contributors: Michael J. Bottery; Norman van Rhijn; Harry Chown; Johanna L. Rhodes; Brandi N. Celia-Sanchez; Marin T. Brewer; Michelle Momany; Matthew C. Fisher; Christopher G. Knight; Michael J. Bromley
Source: check_circle
Crossref

Xenosiderophore transporter gene expression and clade-specific filamentation inCandida auriskillifish infection

2024-10-23 | Preprint
DOI: 10.1101/2024.10.22.619744
Contributors: Hugh Gifford; Tina Bedekovic; Nicolas Helmstetter; Jack Gregory; Qinxi Ma; Alexandra C. Brand; Duncan Wilson; Johanna Rhodes; Mark Ramsdale; Tetsuhiro Kudoh et al.
Source: check_circle
Crossref

What makesCandida aurispan-drug resistant? Integrative insights from genomic, transcriptomic, and phenomic analysis of clinical strains resistant to all four major classes of antifungal drugs

2024-06-18 | Preprint
DOI: 10.1101/2024.06.18.599548
Contributors: Johanna Rhodes; Jonathan Jacobs; Emily K. Dennis; Swati R. Manjari; Nilesh Banavali; Robert Marlow; Mohammed Anower Rokebul; Sudha Chaturvedi; Vishnu Chaturvedi
Source: check_circle
Crossref

Elevated mutation rates in the multi-azole resistantAspergillus fumigatusclade drives rapid evolution of antifungal resistance

2023-12-05 | Preprint
DOI: 10.1101/2023.12.05.570068
Contributors: Michael J. Bottery; Norman van Rhijn; Harry Chown; Johanna L. Rhodes; Brandi N. Celia-Sanchez; Marin T. Brewer; Michelle Momany; Matthew C. Fisher; Christopher G. Knight; Michael J. Bromley
Source: check_circle
Crossref

Airway microbiome: environmental exposure–respiratory health nexus

Trends in Molecular Medicine
2023-11 | Journal article
DOI: 10.1016/j.molmed.2023.08.011
Contributors: Jean-Pierre Gangneux; Johanna L. Rhodes; Nicolas Papon
Source: check_circle
Crossref

Genomic Epidemiology Identifies Azole Resistance Due to TR34/L98H in European Aspergillus fumigatus Causing COVID-19-Associated Pulmonary Aspergillosis

Journal of Fungi
2023-11-13 | Journal article
DOI: 10.3390/jof9111104
Contributors: Benjamin C. Simmons; Johanna Rhodes; Thomas R. Rogers; Paul E. Verweij; Alireza Abdolrasouli; Silke Schelenz; Samuel J. Hemmings; Alida Fe Talento; Auveen Griffin; Mary Mansfield et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Determining the microbial species content in tissue from Alzheimer’s and Parkinson’s Disease patients

2023-10-26 | Preprint
DOI: 10.1101/2023.10.25.563977
Contributors: Rodrigo Leitao; Iam Ut Wan; Matthew C. Fisher; Johanna Rhodes
Source: check_circle
Crossref

Long-read Sequencing and de novo Genome Assembly of Three Aspergillus fumigatus Genomes

Mycopathologia
2023-08 | Journal article
DOI: 10.1007/s11046-023-00740-2
Contributors: Samuel J. Hemmings; Johanna L. Rhodes; Matthew C. Fisher
Source: check_circle
Crossref

Genomic epidemiology of EuropeanAspergillus fumigatuscausing COVID-19-associated pulmonary aspergillosis in Europe

2023-07-24 | Preprint
DOI: 10.1101/2023.07.21.550109
Contributors: B.C. Simmons; J. Rhodes; T.R. Rogers; A.F. Talento; A. Griffin; M Mansfield; D. Sheehan; A. Abdolrasouli; P.E. Verweij; T. Bosch et al.
Source: check_circle
Crossref

Genomic surveillance urgently needed to control wheat blast pandemic spreading across continents

PLOS Biology
2023-04-12 | Journal article
DOI: 10.1371/journal.pbio.3002090
Contributors: Johanna Rhodes
Source: check_circle
Crossref

Phenotypic Variants of Azole-Resistant Aspergillus Fumigatus that Co-exist in Human Respiratory Samples are Genetically Highly Related

Mycopathologia
2022-12 | Journal article
DOI: 10.1007/s11046-022-00665-2
Contributors: Alireza Abdolrasouli; Johanna L. Rhodes
Source: check_circle
Crossref

Publisher Correction: Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment

Nature Microbiology
2022-06-07 | Journal article
DOI: 10.1038/s41564-022-01160-6
Contributors: Johanna Rhodes; Alireza Abdolrasouli; Katie Dunne; Thomas R. Sewell; Yuyi Zhang; Eloise Ballard; Amelie P. Brackin; Norman van Rhijn; Harry Chown; Alexandra Tsitsopoulou et al.
Source: check_circle
Crossref

Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment

Nature Microbiology
2022-04-25 | Journal article
DOI: 10.1038/s41564-022-01091-2
Contributors: Johanna Rhodes; Alireza Abdolrasouli; Katie Dunne; Thomas R. Sewell; Yuyi Zhang; Eloise Ballard; Amelie P. Brackin; Norman van Rhijn; Harry Chown; Alexandra Tsitsopoulou et al.
Source: check_circle
Crossref

Fungal Genomics in Respiratory Medicine: What, How and When?

Mycopathologia
2021-10 | Journal article
DOI: 10.1007/s11046-021-00573-x
Contributors: Amelie P. Brackin; Sam J. Hemmings; Matthew C. Fisher; Johanna Rhodes
Source: check_circle
Crossref

HMMploidy: inference of ploidy levels from short-read sequencing data

2021-06-30 | Preprint
DOI: 10.1101/2021.06.29.450340
Contributors: Samuele Soraggi; Johanna Rhodes; Isin Altinkaya; Oliver Tarrant; François Balloux; Matthew C. Fisher; Matteo Fumagalli
Source: check_circle
Crossref

Rapid Detection of Azole-Resistant Aspergillus fumigatus in Clinical and Environmental Isolates by Use of a Lab-on-a-Chip Diagnostic System

Journal of Clinical Microbiology
2020-10-21 | Journal article
DOI: 10.1128/JCM.00843-20
Contributors: Ling-Shan Yu; Jesus Rodriguez-Manzano; Nicolas Moser; Ahmad Moniri; Kenny Malpartida-Cardenas; Nicholas Miscourides; Thomas Sewell; Tatiana Kochina; Amelie Brackin; Johanna Rhodes et al.
Source: check_circle
Crossref

Elevated Prevalence of Azole-Resistant Aspergillus fumigatus in Urban versus Rural Environments in the United Kingdom

Antimicrobial Agents and Chemotherapy
2019-09 | Journal article
DOI: 10.1128/AAC.00548-19
Contributors: Thomas R. Sewell; Yuyi Zhang; Amelie P. Brackin; Jennifer M. G. Shelton; Johanna Rhodes; Matthew C. Fisher
Source: check_circle
Crossref

Nonrandom Distribution of Azole Resistance across the Global Population of Aspergillus fumigatus

mBio
2019-06-25 | Journal article
DOI: 10.1128/mBio.00392-19
Contributors: Thomas R. Sewell; Jianing Zhu; Johanna Rhodes; Ferry Hagen; Jacques F. Meis; Matthew C. Fisher; Thibaut Jombart; Anuradha Chowdhary; Paul Dyer; Shawn Lockhart
Source: check_circle
Crossref

Elevated prevalence of azole resistant Aspergillus fumigatus in urban versus rural environments in the United Kingdom

2019-04-05 | Other
DOI: 10.1101/598961
Contributors: Thomas R Sewell; Yuyi Zhang; Amelie P Brackin; Jennifer MG Shelton; Johanna Rhodes; Matthew C Fisher
Source: check_circle
Crossref

Transcriptional heterogeneity of VGII compared with non-VGII lineages underpins key pathogenicity pathways

mSphere
2018-10-24 | Journal article | Author
DOI: 10.1128/mSphere.00445-18
SOURCE-WORK-ID:

631f57e9-bc31-4635-b6ec-7985d5a1922e

PMID: 30355668
EID:

2-s2.0-85055598937
Contributors: Rhys A Farrer; Christopher B Ford; Johanna Rhodes; Toni Delorey; Robin May; Matthew C Fisher; Elaine Cloutman-Green; Francois Balloux; Christina A Cuomo
Source: check_circle
University of Birmingham
grade
Preferred source (of 2)‎

Airway persistence by the emerging multi‐azole‐resistant Rasamsonia argillacea complex in cystic fibrosis

Mycoses
2018-09 | Journal article
DOI: 10.1111/myc.12789
Contributors: Alireza Abdolrasouli; Amelia C. Bercusson; Johanna L. Rhodes; Ferry Hagen; Jochem B. Buil; Alison Y. Y. Tang; Leonard L. de Boer; Anand Shah; Andrew J. Milburn; J. Stuart Elborn et al.
Source: check_circle
Crossref

MARDy: Mycology Antifungal Resistance Database

Bioinformatics
2018-09-15 | Journal article
DOI: 10.1093/bioinformatics/bty321
Contributors: Anthony Nash; Thomas Sewell; Rhys A Farrer; Alireza Abdolrasouli; Jennifer M G Shelton; Matthew C Fisher; Johanna Rhodes; Janet Kelso
Source: check_circle
Crossref

Transcriptional heterogeneity of Cryptococcus gattii VGII compared with non-VGII lineages underpins key pathogenicity pathways

2018-08-22 | Other | Author
DOI: 10.1101/396796
SOURCE-WORK-ID:

9a252535-6326-47c9-9e9a-a0082eb65acd
Contributors: Rhys A. Farrer; Christopher B. Ford; Johanna Rhodes; Toni Delorey; Robin May; Matthew C. Fisher; Elaine Cloutman-Green; Francois Balloux; Christina A. Cuomo
Source: check_circle
University of Birmingham
grade
Preferred source (of 2)‎

Breaching Pathogeographic Barriers by the Bat White-Nose Fungus

mBio
2018-07-05 | Journal article
DOI: 10.1128/mBio.00897-18
Contributors: Johanna Rhodes; Matthew C. Fisher
Source: check_circle
Crossref

Rapid genome sequencing for outbreak analysis of the emerging human fungal pathogenCandida auris

2017-10-13 | Preprint
DOI: 10.1101/201343
Contributors: Johanna Rhodes; Alireza Abdolrasouli; Rhys A. Farrer; Christina A. Cuomo; David M. Aanensen; Darius Armstrong-James; Matthew C. Fisher; Silke Schelenz
Source: check_circle
Crossref

Tracing Genetic Exchange and Biogeography of Cryptococcus neoformans var. grubii at the Global Population Level

Genetics
2017-09 | Journal article
DOI: 10.1534/genetics.117.203836
Contributors: Johanna Rhodes; Christopher A. Desjardins; Sean M. Sykes; Mathew A. Beale; Mathieu Vanhove; Sharadha Sakthikumar; Yuan Chen; Sharvari Gujja; Sakina Saif; Anuradha Chowdhary et al.
Source: check_circle
Crossref

Population genomics ofCryptococcus neoformansvar.grubiireveals new biogeographic relationships and finely maps hybridization

2017-05-01 | Preprint
DOI: 10.1101/132894
Contributors: Johanna Rhodes; Christopher A. Desjardins; Sean M. Sykes; Mathew A. Beale; Mathieu Vanhove; Sharadha Sakthikumar; Yuan Chen; Sharvari Gujja; Sakina Saif; Anuradha Chowdhary et al.
Source: check_circle
Crossref

A Population Genomics Approach to Assessing the Genetic Basis of Within-Host Microevolution Underlying Recurrent Cryptococcal Meningitis Infection

G3: Genes|Genomes|Genetics
2017-04 | Journal article
DOI: 10.1534/g3.116.037499
Contributors: Johanna Rhodes; Mathew A. Beale; Mathieu Vanhove; Joseph N. Jarvis; Shichina Kannambath; John A. Simpson; Anthea Ryan; Graeme Meintjes; Thomas S. Harrison; Matthew C. Fisher et al.
Source: check_circle
Crossref

A population genomics approach to assessing the genetic basis of within-host microevolution underlying recurrent cryptococcal meningitis infection

bioRxiv
2016 | Journal article
DOI: 10.1101/083469
ARXIV:

http://biorxiv.org/content/early/2016/10/26/083469.full.pdf
Source: Self-asserted source
Johanna Rhodes
grade
Preferred source (of 2)‎

Simulations of CYP51A from Aspergillus fumigatus in a model bilayer provide insights into triazole drug resistance

bioRxiv
2016 | Journal article
Source: Self-asserted source
Johanna Rhodes

Clinical implications of globally emerging azole resistance in Aspergillus fumigatus

Philosophical Transactions of the Royal Society B: Biological Sciences
2016-12-05 | Journal article
DOI: 10.1098/rstb.2015.0460
Contributors: Jacques F. Meis; Anuradha Chowdhary; Johanna L. Rhodes; Matthew C. Fisher; Paul E. Verweij
Source: check_circle
Crossref

Simulations ofCYP51AfromAspergillus fumigatusin a model bilayer provide insights into triazole drug resistance

2016-11-17 | Preprint
DOI: 10.1101/088468
Contributors: Anthony Nash; Johanna Rhodes
Source: check_circle
Crossref

Genomic context of azole resistance mutations in Aspergillus fumigatus determined using whole-genome sequencing

mBio
2015 | Journal article
DOI: 10.1128/mBio.00536-15
EID:

2-s2.0-84931270515
Contributors: Abdolrasouli, A.; Rhodes, J.; Beale, M.A.; Hagen, F.; Rogers, T.R.; Chowdhary, A.; Meis, J.F.; Armstrong-James, D.; Fisher, M.C.
Source: Self-asserted source
Johanna Rhodes via Scopus - Elsevier

Illuminating choices for library prep: A comparison of library preparation methods for whole genome sequencing of cryptococcus neoformans using Illumina HiSeq

PLoS ONE
2014 | Journal article
DOI: 10.1371/journal.pone.0113501
EID:

2-s2.0-84914703694
Contributors: Rhodes, J.; Beale, M.A.; Fisher, M.C.
Source: Self-asserted source
Johanna Rhodes via Scopus - Elsevier

Wigwams: Identifying gene modules co-regulated across multiple biological conditions

Bioinformatics
2014 | Journal article
DOI: 10.1093/bioinformatics/btt728
EID:

2-s2.0-84897452329
Contributors: Polanski, K.; Rhodes, J.; Hill, C.; Zhang, P.; Jenkins, D.J.; Kiddle, S.J.; Jironkin, A.; Beynon, J.; Buchanan-Wollaston, V.; Ott, S. et al.
Source: Self-asserted source
Johanna Rhodes via Scopus - Elsevier

Arabidopsis defense against Botrytis cinerea: Chronology and regulation deciphered by high-resolution temporal transcriptomic analysis

Plant Cell
2012 | Journal article
DOI: 10.1105/tpc.112.102046
EID:

2-s2.0-84868288164
Contributors: Windram, O.; Madhou, P.; Mchattie, S.; Hill, C.; Hickman, R.; Cooke, E.; Jenkins, D.J.; Penfold, C.A.; Baxter, L.; Breeze, E. et al.
Source: Self-asserted source
Johanna Rhodes via Scopus - Elsevier

Peer review (12 reviews for 6 publications/grants)

Review activity for Communications biology. (1)
Review activity for Fungal biology. (1)
Review activity for Mycopathologia. (5)
Review activity for Nature communications (2)
Review activity for Nature microbiology. (2)
Review activity for Research in Veterinary Science. (1)
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