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Hepatotoxicity, Chronic viral hepatitis, Non-alcoholic fatty liver disease
Spain

Biography

Prof. Raúl J. Andrade is full Professor of Medicine, Faculty of Medicine at the University of Malaga and Director of the Service of Gastroenterology and Hepatology, University Hospital of Málaga (Spain). He is also the director of the Spanish DILI Registry network (www.spanishdili.uma.es) and of the Spanish Latin-American DILI Network (www.slatindili.uma.es).

He is member of The Networked Biomedical Centre for Research into Hepatic and Digestive Diseases (CIBERehd) as the principal investigator. He is also the member of the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP) of the European Medicines Agency (EMA), of the International Serious Adverse Event Consortium (ISAEC), member of the steering committee of the Standardization Phenotype Project of the ISAEC and Expert of the Spanish Medicines Agency in the Evaluation of liver safety of drugs. He is also member of the steering committee of the Group of Special Interest in Hepatotoxicity sponsored by the American Association for the Study of Liver Diseases as well as member of the working team on the Cholestatic and Drug-induced Liver Disease section of the EASL HEPAMAP project. He was guest of Honor of the Medical Sciences Faculty, National University of Rosario of Argentine (2012) and was Part of the Reviewing board for the EASL International Liver Congress™ (2013) He contributes in pre- & postgraduate teaching at University of Málaga (since 1982). He received grants from the European Association for the Study of the Liver (EASL), the Carlos III Health Institute, the Andalusian Ministry of Health, CIBERehd, the Iberoamerican Postgraduate University Association (AUIP), the University of Málaga, the Spanish Foundation for Funcional Gastrointestinal Disorders (FEAD), the Economics, Innovation and Science Regional Ministry, the International SAEC Consortium LTD y Bioiberica S.A. Also, he is partner of the Innovative Medicines Initiative IMI-2008-T5 SAFE-T Safer and faster Evidence Based Translation of the European Union Grant Agreement number 523 705 for the development of biomarkers in drug-induced liver injury. He is member of the editorial board of: Current Drug Safety, World Journal of Gastroenterology, International Journal of Clinical Pharmacology and Therapeutics, Hepatology, Gastroenterology and Hepatology. External referee of : Gastroenterology, Hepatology, Journal of Hepatology, Alimentary Pharmacology &Therapeutics, The Lancet, Drug Safety, Clinical Infectious Diseases among others high rated journals… He published more than 200 articles in peer-review journals, 6 clinical cases, and 43 book chapters. He has an h index of 31. He presented more than 320 communications in International & National Scientific Meetings, either as oral or poster, having the respective abstracts published. He gave more than 120 invited talks in International & National Spanish Meetings.

Activities

Employment (1)

Universidad de Malaga: Málaga, Andalucía, ES

Catedrático de Universidad - CU (Medicina y Dermatología)
Employment
Source: Self-asserted source
Raúl Jesús Andrade Bellido

Works (50 of 214)

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Epigenetic modifications in drug‐induced liver injury: A systematic review

British Journal of Clinical Pharmacology
2025-03-25 | Journal article
Contributors: Romina Lorena de los Santos‐Fernández; Antonio Segovia‐Zafra; Guillermo Paz‐López; Gonzalo Matilla‐Cabello; Hao Niu; Ismael Álvarez‐Álvarez; Camilla Stephens; Andrés González‐Jiménez; M. Isabel Lucena; Raúl J. Andrade et al.
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Crossref

Genetic Variants of GBP4: Reduced Risks for Drug‐Induced Acute Liver Failure in Non‐Finnish European Population

Liver International
2025-02 | Journal article
Contributors: Tsung‐Jen Liao; Menghang Xia; Paul Hayashi; Bohun Pan; Guruprasad P. Aithal; M. Isabel Lucena; Raúl J. Andrade; Jody A. Rule; William M. Lee; Jorge Rakela et al.
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Reply to: “Distinction of autoimmune hepatitis from drug-induced autoimmune like hepatitis: The answer lies at the interface”

Journal of Hepatology
2024-07 | Journal article
Contributors: Einar S. Björnsson; M Isabel Lucena; Raul J. Andrade
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Anticancer drugs are the first cause of drug‐induced liver injury in a reference hospital

Liver International
2024-02 | Journal article
Contributors: Anna Pocurull; Maria José Moreta; David Heitman; Ignasi Olivas; Cristina Collazos; Elia Canga; Joaquin Sáez‐Peñataro; Raul J. Andrade; M. Isabel Lucena; Zoe Mariño et al.
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Crossref

Drug-induced autoimmune-like hepatitis

Clinical Liver Disease
2024-01 | Journal article
Contributors: Miren García-Cortés; Jose M. Pinazo-Bandera; M. Isabel Lucena; Raúl J. Andrade
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Crossref

Response to: Letter to the Editor by Trinh et al. Drug‐induced liver injury registries are important

Liver International
2023-10 | Journal article
Contributors: Einar S. Björnsson; M. Isabel Lucena; Raul J. Andrade; Guruprasad P. Aithal
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Crossref

Drug-induced cholestasis: causative agents and challenges in diagnosis and management

Exploration of Digestive Diseases
2023-09-18 | Journal article
Contributors: Jose M. Pinazo-Bandera; Juan Pedro Toro-Ortiz; Raúl J. Andrade; Miren García-Cortés
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Crossref

Study design for development of novel safety biomarkers of drug-induced liver injury by the translational safety biomarker pipeline (TransBioLine) consortium: a study protocol for a nested case–control study

Diagnostic and Prognostic Research
2023-09-12 | Journal article
Contributors: Jane I. Grove; Camilla Stephens; M. Isabel Lucena; Raúl J. Andrade; Sabine Weber; Alexander Gerbes; Einar S. Bjornsson; Guido Stirnimann; Ann K. Daly; Matthias Hackl et al.
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Crossref

Treatment responses and outcomes in patients with autoimmune hepatitis and concomitant features of non-alcoholic fatty liver disease

JHEP Reports
2023-08 | Journal article
Contributors: Kalliopi Zachou; Kalliopi Azariadis; Ellina Lytvyak; Romée J.A.L.M. Snijders; Atsushi Takahashi; Nikolaos K. Gatselis; Mercedes Robles; Raul J. Andrade; Christoph Schramm; Ansgar W. Lohse et al.
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Crossref

Liver fibrosis with methotrexate — an overestimated risk?

Nature Reviews Gastroenterology & Hepatology
2023-06 | Journal article
Contributors: Raul J. Andrade; Einar S. Björnsson
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Crossref

Potential benefit and lack of serious risk from corticosteroids in drug‐induced liver injury: An international, multicentre, propensity score‐matched analysis

Alimentary Pharmacology & Therapeutics
2023-04 | Journal article
Contributors: Hao Niu; Jiayi Ma; Inmaculada Medina‐Caliz; Mercedes Robles‐Diaz; Elvira Bonilla‐Toyos; Marwan Ghabril; Mª Isabel Lucena; Ismael Alvarez‐Alvarez; Raul J. Andrade
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Crossref

Membrane Vesicles of Toxigenic Clostridioides difficile Affect the Metabolism of Liver HepG2 Cells

Antioxidants
2023-03-27 | Journal article
Contributors: Estefanía Caballano-Infantes; Ailec Ho-Plágaro; Carlos López-Gómez; Flores Martín-Reyes; Francisca Rodríguez-Pacheco; Bernard Taminiau; Georges Daube; Lourdes Garrido-Sánchez; Guillermo Alcaín-Martínez; Raúl J. Andrade et al.
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Assessment of the Frequency, Phenotypes, and Outcomes of Acute Liver Injury Associated with Amoxicillin/Clavulanate in 1.4 Million Patients in the Veterans Health Administration

Drug Safety
2023-02 | Journal article
Contributors: Ayako Suzuki; Hans Tillmann; James Williams; Ronald G. Hauser; Julie Frund; Mizuki Suzuki; Fred Prior; Guruprasad P. Aithal; M. Isabel Lucena; Raúl J. Andrade et al.
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Crossref

Organophosphate pesticides: Another silent liver hazard?

Liver International
2023-02 | Journal article
Contributors: Ismael Alvarez‐Alvarez; Raúl J. Andrade
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Crossref

Therapeutic Management of Idiosyncratic Drug-Induced Liver Injury and Acetaminophen Hepatotoxicity in the Paediatric Population: A Systematic Review

Drug Safety
2022-11 | Journal article
Contributors: Hao Niu; Edmond Atallah; Ismael Alvarez-Alvarez; Inmaculada Medina-Caliz; Guruprasad P. Aithal; Cigdem Arikan; Raul J. Andrade; M. Isabel Lucena
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Crossref

Recreational Drugs and the Risk of Hepatocellular Carcinoma

Cancers
2022-11-02 | Journal article
Contributors: José M. Pinazo-Bandera; Miren García-Cortés; Antonio Segovia-Zafra; María Isabel Lucena; Raúl J. Andrade
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Methionine Cycle Rewiring by Targeting miR-873-5p Modulates Ammonia Metabolism to Protect the Liver from Acetaminophen

Antioxidants
2022-04 | Journal article | Author
Contributors: Rubén Rodríguez Agudo; Naroa Goikoetxea-Usandizaga; Marina Serrano-Maciá; Pablo Fernández-Tussy; David Fernández-Ramos; Sofia Lachiondo-Ortega; Irene González-Recio; Clàudia Gil-Pitarch; María Mercado-Gómez; Laura Morán et al.
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Multidisciplinary Digital Publishing Institute

Differential iNKT and T Cells Activation in Non-Alcoholic Fatty Liver Disease and Drug-Induced Liver Injury

Biomedicines
2021-12 | Journal article | Author
Contributors: Estefanía Caballano Infantes; García-García, AM; López-Gómez C; Alejandro Cueto; Mercedes Robles-Diaz; Aida Ortega-Alonso; Flores Martín-Reyes; Ismael Alvarez-Alvarez; Isabel Arranz-Salas; Francisco Ruíz-Cabello et al.
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Multidisciplinary Digital Publishing Institute

Preclinical models of idiosyncratic drug-induced liver injury (iDILI): Moving towards prediction

Acta Pharmaceutica Sinica B
2021-12 | Journal article
Contributors: Antonio Segovia-Zafra; Daniel E. Di Zeo-Sánchez; Carlos López-Gómez; Zeus Pérez-Valdés; Eduardo García-Fuentes; Raúl J. Andrade; M. Isabel Lucena; Marina Villanueva-Paz
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Crossref

Critical Review of Gaps in the Diagnosis and Management of Drug-Induced Liver Injury Associated with Severe Cutaneous Adverse Reactions

Journal of Clinical Medicine
2021-11-15 | Journal article
Contributors: Marina Villanueva-Paz; Hao Niu; Antonio Segovia-Zafra; Inmaculada Medina-Caliz; Judith Sanabria-Cabrera; M. Isabel Lucena; Raúl J. Andrade; Ismael Alvarez-Alvarez
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Drug properties and host factors contribute to biochemical presentation of drug-induced liver injury: a prediction model from a machine learning approach

Archives of Toxicology
2021-05-05 | Journal article
Contributors: Andres Gonzalez-Jimenez; Ayako Suzuki; Minjun Chen; Kristin Ashby; Ismael Alvarez-Alvarez; Raul J. Andrade; M. Isabel Lucena
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Crossref

Immune-Mediated Drug-Induced Liver Injury: Immunogenetics and Experimental Models

International Journal of Molecular Sciences
2021-04-27 | Journal article
Contributors: Alessio Gerussi; Ambra Natalini; Fabrizio Antonangeli; Clara Mancuso; Elisa Agostinetto; Donatella Barisani; Francesca Di Rosa; Raul Andrade; Pietro Invernizzi
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Crossref
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Oxidative Stress in Drug-Induced Liver Injury (DILI): From Mechanisms to Biomarkers for Use in Clinical Practice

Antioxidants
2021-03-05 | Journal article
Contributors: Marina Villanueva-Paz; Laura Morán; Nuria López-Alcántara; Cristiana Freixo; Raúl J. Andrade; M Isabel Lucena; Francisco Javier Cubero
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Profile of herbal and dietary supplements induced liver injury in Latin America: A systematic review of published reports

Phytotherapy Research
2021-01 | Journal article
Contributors: Genario Santos; Jessica Gasca; Raymundo Parana; Vinicius Nunes; Maria Schinnoni; Inmaculada Medina‐Caliz; Maria Rosario Cabello; Maria Isabel Lucena; Raul J. Andrade
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Crossref

Systematic review: ibuprofen‐induced liver injury

Alimentary Pharmacology & Therapeutics
2020-03 | Journal article
Contributors: Miguel E. Zoubek; María Isabel Lucena; Raúl J. Andrade; Camilla Stephens
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Crossref

Drug-Induced liver Injury Associated with Severe Cutaneous Hypersensitivity Reactions: A Complex Entity in Need of a Multidisciplinary Approach

Current Pharmaceutical Design
2019-12-12 | Journal article
Contributors: Judith Sanabria-Cabrera; Inmaculada Medina-Cáliz; Simona Stankevičiūtė; Antonio Rodríguez-Nicolás; Marina Almarza-Torres; M. Isabel Lucena; Raúl J. Andrade
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Crossref

Shared Genetic Risk Factors Across Carbamazepine‐Induced Hypersensitivity Reactions

Clinical Pharmacology & Therapeutics
2019-11 | Journal article
Contributors: Paola Nicoletti; Sarah Barrett; Laurence McEvoy; Ann K. Daly; Guruprasad Aithal; M. Isabel Lucena; Raul J. Andrade; Mia Wadelius; Pär Hallberg; Camilla Stephens et al.
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Crossref

Landscape of Liver Injury From Herbal and Dietary Supplements in Europe, Latin America, and Asia

Clinical Liver Disease
2019-08 | Journal article
Contributors: Raul J. Andrade
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Crossref

Reply letter to “Editorial: bodybuilders beware”

Alimentary Pharmacology & Therapeutics
2019-08 | Journal article
Contributors: Mercedes Robles‐Diaz; Inmaculada Medina‐Cáliz; Raúl J. Andrade; M. Isabel Lucena
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Crossref

Herbal‐induced liver injury: The price to pay for a healthier life?

Liver International
2019-02 | Journal article
Contributors: Raúl J. Andrade
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Crossref

Drug, Herb, and Dietary Supplement Hepatotoxicity

International Journal of Molecular Sciences
2016-09 | Journal article
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Multidisciplinary Digital Publishing Institute
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Preferred source (of 2)‎

Case Characterization, Clinical Features and Risk Factors in Drug-Induced Liver Injury

International Journal of Molecular Sciences
2016-05 | Journal article
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Multidisciplinary Digital Publishing Institute
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Preferred source (of 2)‎

Hepatotoxicity by Dietary Supplements: A Tabular Listing and Clinical Characteristics

International Journal of Molecular Sciences
2016-04-09 | Journal article
Contributors: Miren García-Cortés; Mercedes Robles-Díaz; Aida Ortega-Alonso; Inmaculada Medina-Caliz; Raul Andrade
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Crossref

Drug-induced autoimmune liver disease: A diagnostic dilemma of an increasingly reported disease

2014 | Journal article
DOI:

10.4254/wjh.v6.i4.160

EID:

2-s2.0-84901231423

Contributors: Castiella, A.; Zapata, E.; Lucena, M.I.; Andrade, R.J.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

Drug-induced liver injury due to antimicrobials, central nervous system agents, and nonsteroidal anti-inflammatory drugs

2014 | Journal article
DOI:

10.1055/s-0034-1375956

EID:

2-s2.0-84901813321

Contributors: Devarbhavi, H.; Andrade, R.J.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

Hepatitis C virus infection alters lipid metabolism depending on IL28B polymorphism and viral genotype and modulates gene expression in vivo and in vitro

2014 | Journal article
DOI:

10.1111/jvh.12209

EID:

2-s2.0-84890553992

Contributors: Rojas, Á.; Del Campo, J.A.; Maraver, M.; Aparcero, R.; García-Valdecasas, M.; Diago, M.; Carmona, I.; Andrade, R.J.; Solà, R.; Romero-Gõmez, M.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

Mechanisms of drug-induced liver injury

2014 | Journal article
DOI:

10.1097/ACI.0000000000000070

EID:

2-s2.0-84903787701

Contributors: Stephens, C.; Andrade, R.J.; Lucena, M.I.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

PNPLA3 rs738409 causes steatosis according to viral & IL28B genotypes in hepatitis C

2014 | Journal article
EID:

2-s2.0-84902385227

Contributors: Ampuero, J.; Del Campo, J.A.; Rojas, L.; García-Lozano, J.R.; Solá, R.; Andrade, R.; Pons, J.A.; Navarro, J.M.; Calleja, J.L.; Buti, M. et al.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

Profile of idiosyncratic drug induced liver injury in Latin America. An analysis of published reports

2014 | Journal article
EID:

2-s2.0-84893671361

Contributors: Hernández, N.; Bessone, F.; Sánchez, A.; Di Pace, M.; Brahm, J.; Zapata, R.; Chirino, R.A.; Dávalos, M.; Méndez-Sánchez, N.; Arrese, M. et al.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

Selected ABCB1, ABCB4 and ABCC2 polymorphisms do not enhance the risk of drug-induced hepatotoxicity in a Spanish cohort

2014 | Journal article
DOI:

10.1371/journal.pone.0094675

EID:

2-s2.0-84899638203

Contributors: Ulzurrun, E.; Stephens, C.; Ruiz-Cabello, F.; Robles-Diaz, M.; Saenz-López, P.; Hallal, H.; Soriano, G.; Roman, E.; Fernandez, M.C.; Lucena, M.I. et al.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

Use of hy's law and a new composite algorithm to predict acute liver failure in patients with drug-induced liver injury

2014 | Journal article
DOI:

10.1053/j.gastro.2014.03.050

EID:

2-s2.0-84903207339

Contributors: Robles-Diaz, M.; Isabel Lucena, M.; Kaplowitz, N.; Stephens, C.; Medina-Cáliz, I.; González-Jimenez, A.; Ulzurrun, E.; Gonzalez, A.F.; Fernandez, M.C.; Romero-Gómez, M. et al.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

Biochemical and pharmacological features of telaprevir | Aspectos bioquímicos y farmacológicos de telaprevir

2013 | Journal article
DOI:

10.1016/S0213-005X(13)70117-4

EID:

2-s2.0-84884664609

Contributors: Andrade, R.J.; García-Samaniego, J.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

HLA Alleles Influence the Clinical Signature of Amoxicillin-Clavulanate Hepatotoxicity

2013 | Journal article
DOI:

10.1371/journal.pone.0068111

EID:

2-s2.0-84879990042

Contributors: Stephens, C.; López-Nevot, M.-A.; Ruiz-Cabello, F.; Ulzurrun, E.; Soriano, G.; Romero-Gómez, M.; Moreno-Casares, A.; Lucena, M.I.; Andrade, R.J.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

Role of chemical structures and the 1331T>C bile salt export pump polymorphism in idiosyncratic drug-induced liver injury

2013 | Journal article
DOI:

10.1111/liv.12193

EID:

2-s2.0-84883777383

Contributors: Ulzurrun, E.; Stephens, C.; Crespo, E.; Ruiz-Cabello, F.; Ruiz-Nuñez, J.; Saenz-López, P.; Moreno-Herrera, I.; Robles-Díaz, M.; Hallal, H.; Moreno-Planas, J.M. et al.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

A rare cause of intestinal obstruction in the adult: Duodenal diaphragm

2012 | Journal article
EID:

2-s2.0-84867261265

Contributors: Jiménez-Moreno, M.A.; Fernández-Crehuet, C.; Ferreiro-Argüelles, B.; Calle-Calle, J.; Andrade-Bellido, R.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

Building a Spanish-Latin American network on drug-induced liver injury: Much to get from a joint collaborative initiative

2012 | Journal article
EID:

2-s2.0-84862016967

Contributors: Bessone, F.; Hernandez, N.; Dávalos, M.; Paraná, R.; Schinoni, M.I.; Lizarzabal, M.; Kershenobich, D.; Loaeza, A.; Arrese, M.; Chirino, R.A. et al.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

Genetic variations in drug-induced liver injury (DILI): Resolving the puzzle

2012 | Journal article
DOI:

10.3389/fgene.2012.00253

EID:

2-s2.0-84876120471

Contributors: Stephens, C.; Lucena, M.I.; Andrade, R.J.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

Metformin-induced hepatotoxicity

2012 | Journal article
DOI:

10.2337/dc11-2306

EID:

2-s2.0-84859027311

Contributors: Miralles-Linares, F.; Puerta-Fernandez, S.; Bernal-Lopez, M.R.; Tinahones, F.J.; Andrade, R.J.; Gomez-Huelgas, R.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

Obesity-dependent metabolic signatures associated with nonalcoholic fatty liver disease progression

2012 | Journal article
DOI:

10.1021/pr201223p

EID:

2-s2.0-84859568138

Contributors: Barr, J.; Caballería, J.; Martínez-Arranz, I.; Domínguez-Díez, A.; Alonso, C.; Muntané, J.; Pérez-Cormenzana, M.; García-Monzón, C.; Mayo, R.; Martín-Duce, A. et al.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier

Plasma Ribavirin trough concentrations during treatment of chronic hepatitis C in genotype-1 patients

2012 | Journal article
DOI:

10.1097/MCG.0b013e318237123f

EID:

2-s2.0-84858862580

Contributors: De-Rueda, P.M.; Ruiz-Extremera, A.; Candel, J.M.; Quiles, R.; Martín, A.B.; Diago, M.; Andrade, R.; Navarro, J.M.; Gila, A.; León, J. et al.
Source: Self-asserted source
Raúl Jesús Andrade Bellido via Scopus - Elsevier
Items per page:
Page 1 of 5

Peer review (10 reviews for 5 publications/grants)

Review activity for Clinical gastroenterology and hepatology (5)
Review activity for Drug safety. (1)
Review activity for JHEP reports. (2)
Review activity for Journal of clinical and experimental hepatology. (1)
Review activity for Journal of hepatology. (1)