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Works (21)

Development of a Novel Microphysiological System for Peripheral Neurotoxicity Prediction Using Human iPSC-Derived Neurons with Morphological Deep Learning

Toxics
2024-11-11 | Journal article
DOI: 10.3390/toxics12110809
Part of ISSN: 2305-6304
Contributors: Xiaobo Han; Naoki Matsuda; Makoto Yamanaka; Ikuro Suzuki
Source: Self-asserted source
Ikuro Suzuki

Development of an evaluation method for addictive compounds based on electrical activity of human iPS cell‐derived dopaminergic neurons using microelectrode array

Addiction Biology
2024-10 | Journal article
DOI: 10.1111/adb.13443
Contributors: Yuto Ishibashi; Nami Nagafuku; Shingo Kimura; Xiaobo Han; Ikuro Suzuki
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Evaluation of neurotoxicity for pesticide-related compounds in human iPS cell-derived neurons using microelectrode array

Toxicology in Vitro
2023-12 | Journal article
DOI: 10.1016/j.tiv.2023.105668
Part of ISSN: 0887-2333
Contributors: Yuto Ishibashi; Nami Nagafuku; Yasunari Kanda; Ikuro Suzuki
Source: Self-asserted source
Ikuro Suzuki
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An In Vitro Assessment Method for Chemotherapy-Induced Peripheral Neurotoxicity Caused by Anti-Cancer Drugs Based on Electrical Measurement of Impedance Value and Spontaneous Activity

Pharmaceutics
2023-12-16 | Journal article
DOI: 10.3390/pharmaceutics15122788
Part of ISSN: 1999-4923
Contributors: Xiaobo Han; Naoki Matsuda; Yuto Ishibashi; Mikako Shibata; Ikuro Suzuki
Source: Self-asserted source
Ikuro Suzuki

Verification of the seizure liability of compounds based on their in vitro functional activity in cultured rat cortical neurons and co-cultured human iPSC-derived neurons with astrocytes and in vivo extrapolation to cerebrospinal fluid concentration

Toxicology and Applied Pharmacology
2023-10 | Journal article
DOI: 10.1016/j.taap.2023.116675
Part of ISSN: 0041-008X
Contributors: Y. Ishibashi; N. Nagafuku; K. Kinoshita; A. Okamura; T. Shirakawa; I. Suzuki
Source: Self-asserted source
Ikuro Suzuki
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Contraindicated Drug Responses in Dravet Syndrome Brain Organoids Utilizing Micro Electrode Array Assessment Methods

Organoids
2023-10-26 | Journal article
DOI: 10.3390/organoids2040014
Part of ISSN: 2674-1172
Contributors: Remi Yokoi; Nami Nagafuku; Yuto Ishibashi; Naoki Matsuda; Ikuro Suzuki
Source: Self-asserted source
Ikuro Suzuki

Large‐Area Field Potential Imaging Having Single Neuron Resolution Using 236 880 Electrodes CMOS‐MEA Technology

Advanced Science
2023-07 | Journal article
DOI: 10.1002/advs.202207732
Contributors: Ikuro Suzuki; Naoki Matsuda; Xiaobo Han; Shuhei Noji; Mikako Shibata; Nami Nagafuku; Yuto Ishibashi
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Detection of astrocytic slow oscillatory activity and response to seizurogenic compounds using planar microelectrode array

Frontiers in Neuroscience
2023-01-10 | Journal article
DOI: 10.3389/fnins.2022.1050150
Part of ISSN: 1662-453X
Contributors: Taeko Kuroda; Naoki Matsuda; Yuto Ishibashi; Ikuro Suzuki
Source: Self-asserted source
Ikuro Suzuki

Responses to antibiotics in human iPSC-derived neurons based on the clinical antibiotic-associated encephalopathy classification

The Journal of Toxicological Sciences
2022 | Journal article
DOI: 10.2131/jts.47.429
Part of ISSN: 0388-1350
Part of ISSN: 1880-3989
Contributors: Yuto Ishibashi; Shingo Kimura; Ikuro Suzuki
Source: Self-asserted source
Ikuro Suzuki

A functional neuron maturation device provides convenient application on microelectrode array for neural network measurement

Biomaterials Research
2022-09-30 | Journal article
DOI: 10.1186/s40824-022-00324-z
Contributors: Xiaobo Han; Naoki Matsuda; Yuto Ishibashi; Aoi Odawara; Sayuri Takahashi; Norie Tooi; Koshi Kinoshita; Ikuro Suzuki
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<i>In Vitro</i> Pain Assay Using Human iPSC-Derived Sensory Neurons and Microelectrode Array

Toxicological Sciences
2022-06-28 | Journal article
DOI: 10.1093/toxsci/kfac045
Part of ISSN: 1096-6080
Part of ISSN: 1096-0929
Contributors: Aoi Odawara; Mikako Shibata; Yuto Ishibashi; Nami Nagafuku; Naoki Matsuda; Ikuro Suzuki
Source: Self-asserted source
Ikuro Suzuki

Electrophysiological responses to seizurogenic compounds dependent on E/I balance in human iPSC-derived cortical neural networks

Journal of Pharmacological Sciences
2022-02 | Journal article
DOI: 10.1016/j.jphs.2021.12.006
Part of ISSN: 1347-8613
Contributors: R. Yokoi; T. Shigemoto-Kuroda; N. Matsuda; A. Odawara; I. Suzuki
Source: Self-asserted source
Ikuro Suzuki

Raster plots machine learning to predict the seizure liability of drugs and to identify drugs

Scientific Reports
2022-02-10 | Journal article
DOI: 10.1038/s41598-022-05697-8
Part of ISSN: 2045-2322
Contributors: N. Matsuda; A. Odawara; K. Kinoshita; A. Okamura; T. Shirakawa; I. Suzuki
Source: Self-asserted source
Ikuro Suzuki

Analysis of signal components &lt; 500 Hz in brain organoids coupled to microelectrode arrays: A reliable test-bed for preclinical seizure liability assessment of drugs and screening of antiepileptic drugs

Biochemistry and Biophysics Reports
2021-12 | Journal article
DOI: 10.1016/j.bbrep.2021.101148
Part of ISSN: 2405-5808
Contributors: R. Yokoi; M. Shibata; A. Odawara; Y. Ishibashi; N. Nagafuku; N. Matsuda; I. Suzuki
Source: Self-asserted source
Ikuro Suzuki

Approach to Neurotoxicity using Human iPSC Neurons: Consortium for Safety Assessment using Human iPS Cells

Current Pharmaceutical Biotechnology
2020-06-09 | Journal article
DOI: 10.2174/1389201020666191129103730
Part of ISSN: 1389-2010
Contributors: Takafumi Shirakawa; Ikuro Suzuki
Source: Self-asserted source
Ikuro Suzuki

Impact of Sleep–Wake-Associated Neuromodulators and Repetitive Low-Frequency Stimulation on Human iPSC-Derived Neurons

Frontiers in Neuroscience
2019-05-29 | Journal article
DOI: 10.3389/fnins.2019.00554
Part of ISSN: 1662-453X
Contributors: Remi Yokoi; Miho Okabe; Naoki Matsuda; Aoi Odawara; Akihiro Karashima; Ikuro Suzuki
Source: Self-asserted source
Ikuro Suzuki

Toxicological evaluation of convulsant and anticonvulsant drugs in human induced pluripotent stem cell-derived cortical neuronal networks using an MEA system

Scientific Reports
2018-07-10 | Journal article
DOI: 10.1038/s41598-018-28835-7
Part of ISSN: 2045-2322
Contributors: A. Odawara; N. Matsuda; Y. Ishibashi; R. Yokoi; I. Suzuki
Source: Self-asserted source
Ikuro Suzuki

Detection of synchronized burst firing in cultured human induced pluripotent stem cell-derived neurons using a 4-step method

Biochemical and Biophysical Research Communications
2018-03 | Journal article
DOI: 10.1016/j.bbrc.2018.02.117
Part of ISSN: 0006-291X
Contributors: N. Matsuda; A. Odawara; H. Katoh; N. Okuyama; R. Yokoi; I. Suzuki
Source: Self-asserted source
Ikuro Suzuki

Physiological maturation and drug responses of human induced pluripotent stem cell-derived cortical neuronal networks in long-term culture

Scientific Reports
2016-05-18 | Journal article
DOI: 10.1038/srep26181
Part of ISSN: 2045-2322
Contributors: A. Odawara; H. Katoh; N. Matsuda; I. Suzuki
Source: Self-asserted source
Ikuro Suzuki

Induction of long-term potentiation and depression phenomena in human induced pluripotent stem cell-derived cortical neurons

Biochemical and Biophysical Research Communications
2016-01 | Journal article
DOI: 10.1016/j.bbrc.2015.12.087
Part of ISSN: 0006-291X
Contributors: A. Odawara; H. Katoh; N. Matsuda; I. Suzuki
Source: Self-asserted source
Ikuro Suzuki

Long-term electrophysiological activity and pharmacological response of a human induced pluripotent stem cell-derived neuron and astrocyte co-culture

Biochemical and Biophysical Research Communications
2014-01 | Journal article
DOI: 10.1016/j.bbrc.2013.12.142
Part of ISSN: 0006-291X
Contributors: A. Odawara; Y. Saitoh; A.H. Alhebshi; M. Gotoh; I. Suzuki
Source: Self-asserted source
Ikuro Suzuki
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