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Bioinformatics, Hepatology, Metabolic inflammation
United Kingdom

Biography

http://orca-mwe.cf.ac.uk/view/cardiffauthors/A2234625C.html

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Works (50 of 161)

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Page 1 of 4

CXCL12-Targeted Immunomodulatory Gene Therapy Reduces Radiation-Induced Fibrosis in Healthy Tissues

Molecular Cancer Therapeutics
2025-03-04 | Journal article
Contributors: James T. Paget; Joseph A. Ward; Andrew R. McKean; David C. Mansfield; Martin McLaughlin; Joan N. Kyula-Currie; Henry G. Smith; Victoria Roulstone; Chunhei Li; You Zhou et al.
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Data from CXCL12-Targeted Immunomodulatory Gene Therapy Reduces Radiation-Induced Fibrosis in Healthy Tissues

2025-03-04 | Preprint
Contributors: James T. Paget; Joseph A. Ward; Andrew R. McKean; David C. Mansfield; Martin McLaughlin; Joan N. Kyula-Currie; Henry G. Smith; Victoria Roulstone; Chunhei Li; You Zhou et al.
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Supplementary Figure 1 from CXCL12-Targeted Immunomodulatory Gene Therapy Reduces Radiation-Induced Fibrosis in Healthy Tissues

2025-03-04 | Preprint
Contributors: James T. Paget; Joseph A. Ward; Andrew R. McKean; David C. Mansfield; Martin McLaughlin; Joan N. Kyula-Currie; Henry G. Smith; Victoria Roulstone; Chunhei Li; You Zhou et al.
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Supplementary Figure 2 from CXCL12-Targeted Immunomodulatory Gene Therapy Reduces Radiation-Induced Fibrosis in Healthy Tissues

2025-03-04 | Preprint
Contributors: James T. Paget; Joseph A. Ward; Andrew R. McKean; David C. Mansfield; Martin McLaughlin; Joan N. Kyula-Currie; Henry G. Smith; Victoria Roulstone; Chunhei Li; You Zhou et al.
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Supplementary Figure 3 from CXCL12-Targeted Immunomodulatory Gene Therapy Reduces Radiation-Induced Fibrosis in Healthy Tissues

2025-03-04 | Preprint
Contributors: James T. Paget; Joseph A. Ward; Andrew R. McKean; David C. Mansfield; Martin McLaughlin; Joan N. Kyula-Currie; Henry G. Smith; Victoria Roulstone; Chunhei Li; You Zhou et al.
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Supplementary Figure 4 from CXCL12-Targeted Immunomodulatory Gene Therapy Reduces Radiation-Induced Fibrosis in Healthy Tissues

2025-03-04 | Preprint
Contributors: James T. Paget; Joseph A. Ward; Andrew R. McKean; David C. Mansfield; Martin McLaughlin; Joan N. Kyula-Currie; Henry G. Smith; Victoria Roulstone; Chunhei Li; You Zhou et al.
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Supplementary Figure 5 from CXCL12-Targeted Immunomodulatory Gene Therapy Reduces Radiation-Induced Fibrosis in Healthy Tissues

2025-03-04 | Preprint
Contributors: James T. Paget; Joseph A. Ward; Andrew R. McKean; David C. Mansfield; Martin McLaughlin; Joan N. Kyula-Currie; Henry G. Smith; Victoria Roulstone; Chunhei Li; You Zhou et al.
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Supplementary Table 1 from CXCL12-Targeted Immunomodulatory Gene Therapy Reduces Radiation-Induced Fibrosis in Healthy Tissues

2025-03-04 | Preprint
Contributors: James T. Paget; Joseph A. Ward; Andrew R. McKean; David C. Mansfield; Martin McLaughlin; Joan N. Kyula-Currie; Henry G. Smith; Victoria Roulstone; Chunhei Li; You Zhou et al.
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Supplementary Table 2 from CXCL12-Targeted Immunomodulatory Gene Therapy Reduces Radiation-Induced Fibrosis in Healthy Tissues

2025-03-04 | Preprint
Contributors: James T. Paget; Joseph A. Ward; Andrew R. McKean; David C. Mansfield; Martin McLaughlin; Joan N. Kyula-Currie; Henry G. Smith; Victoria Roulstone; Chunhei Li; You Zhou et al.
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Supplementary Table 3 from CXCL12-Targeted Immunomodulatory Gene Therapy Reduces Radiation-Induced Fibrosis in Healthy Tissues

2025-03-04 | Preprint
Contributors: James T. Paget; Joseph A. Ward; Andrew R. McKean; David C. Mansfield; Martin McLaughlin; Joan N. Kyula-Currie; Henry G. Smith; Victoria Roulstone; Chunhei Li; You Zhou et al.
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Insight into the function of the Golgi membrane protein GOLM1 in cholangiocytes through interactomic analysis

FEBS Letters
2025-02 | Journal article
Contributors: Meghana Nagaraj; Sharath Kumar Goud Emmagouni; Vaishali Chaurasiya; Luyang Li; Van Dien Nguyen; Salla Keskitalo; Markku Varjosalo; You Zhou; P. A. Nidhina Haridas; Vesa M. Olkkonen
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Villin‐1 regulates ferroptosis in colorectal cancer progression

The FEBS Journal
2024-12-10 | Journal article
Contributors: Bangli Hu; Yixin Yin; Birong Zhang; Siqi Li; Kezhi Li; You Zhou; Qinghua Huang
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From complement to complosome in non‐alcoholic fatty liver disease: When location matters

Liver International
2024-02 | Journal article
Contributors: Van‐Dien Nguyen; Timothy R. Hughes; You Zhou
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C5aR2 Regulates STING-Mediated Interferon Beta Production in Human Macrophages

Cells
2023-11 | Journal article | Author
Contributors: Oliver Wright; Anna Harris; Van Dien Nguyen; YOU ZHOU; Maxim Durand; Abbie Jayyaratnam; Darren Gormley; Luke A. J. O’Neill; Kathy Triantafilou; Eva-Maria Nichols et al.
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Multidisciplinary Digital Publishing Institute
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NETosis promotes chronic inflammation and fibrosis in systemic lupus erythematosus and COVID-19.

Clinical immunology (Orlando, Fla.)
2023-07-05 | Journal article
Contributors: Lin H; Liu J; Li N; Zhang B; Nguyen VD; Yao P; Feng J; Liu Q; Chen Y; Li G et al.
Source: Self-asserted source
YOU ZHOU
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One-step generation of auxin-inducible degron cells with high-efficiency homozygous tagging

2023-03-27 | Preprint
Contributors: Shiqian Li; Yafei Wang; Miesje van der Stoel; Xin Zhou; Shrinidhi Madhusudan; Kristiina Kanerva; Van Dien Nguyen; Nazli Eskici; Vesa M Olkkonen; You Zhou et al.
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GOLM1 depletion modifies cellular sphingolipid metabolism and adversely affects cell growth

Journal of Lipid Research
2022-09 | Journal article
Contributors: Meghana Nagaraj; Marcus Höring; Maria A. Ahonen; Van Dien Nguyen; You Zhou; Helena Vihinen; Eija Jokitalo; Gerhard Liebisch; P.A. Nidhina Haridas; Vesa M. Olkkonen
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A compound directed against S6K1 hampers fat mass expansion and mitigates diet-induced hepatosteatosis

JCI Insight
2022-07-22 | Journal article
Contributors: Aina Lluch; Sonia R. Veiga; Jèssica Latorre; José M. Moreno-Navarrete; Núria Bonifaci; Van Dien Nguyen; You Zhou; Marcus Höring; Gerhard Liebisch; Vesa M. Olkkonen et al.
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Prostaglandin E 2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells

Science Advances
2021-02-12 | Journal article
Contributors: Siobhan Crittenden; Marie Goepp; Jolinda Pollock; Calum T. Robb; Danielle J. Smyth; You Zhou; Robert Andrews; Victoria Tyrrell; Konstantinos Gkikas; Alexander Adima et al.
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The PNPLA3‐I148M variant increases polyunsaturated triglycerides in human adipose tissue

Liver International
2020-09 | Journal article
Contributors: Sami Qadri; Susanna Lallukka‐Brück; Panu K. Luukkonen; You Zhou; Amalia Gastaldelli; Marju Orho‐Melander; Henna Sammalkorpi; Anne Juuti; Anne K. Penttilä; Julia Perttilä et al.
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Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids

JCI Insight
2019-08-22 | Journal article
Contributors: Panu K. Luukkonen; Auli Nick; Maarit Hölttä-Vuori; Christoph Thiele; Elina Isokuortti; Susanna Lallukka-Brück; You Zhou; Antti Hakkarainen; Nina Lundbom; Markku Peltonen et al.
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Circular RNA hsa_circ_001783 regulates breast cancer progression via sponging miR-200c-3p

Cell Death & Disease
2019-01-22 | Journal article
Contributors: Zihao Liu; You Zhou; Gehao Liang; Yun Ling; Weige Tan; Luyuan Tan; Robert Andrews; Wenjing Zhong; Xuanxuan Zhang; Erwei Song et al.
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Fat accumulates preferentially in the right rather than the left liver lobe in non-diabetic subjects

Digestive and Liver Disease
2018 | Journal article
Source: Self-asserted source
YOU ZHOU

OSBP-related protein-2 (ORP2): a novel Akt effector that controls cellular energy metabolism

Cellular and Molecular Life Sciences
2018 | Journal article
Source: Self-asserted source
YOU ZHOU

Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars

Diabetes care
2018 | Journal article
Source: Self-asserted source
YOU ZHOU

Specific oxygenation of plasma membrane phospholipids by Pseudomonas aeruginosa lipoxygenase induces structural and functional alterations in mammalian cells

Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids
2018 | Journal article
Source: Self-asserted source
YOU ZHOU

Analysis of ORP2-knockout hepatocytes uncovers a novel function in actin cytoskeletal regulation

The FASEB Journal
2017 | Journal article
Source: Self-asserted source
YOU ZHOU

Angiopoietin-like 8 (Angptl8) controls adipocyte lipolysis and phospholipid composition

Chemistry and physics of lipids
2017 | Journal article
Source: Self-asserted source
YOU ZHOU

Angiopoietin-like 8 (Angptl8) controls adipocyte lipolysis and phospholipid composition

Atherosclerosis
2017 | Journal article
Source: Self-asserted source
YOU ZHOU

Gadoxetic acid disodium--enhanced magnetic resonance imaging outperformed multidetector computed tomography in diagnosing small hepatocellular carcinoma: A meta-analysis

Liver Transplantation
2017 | Journal article
Source: Self-asserted source
YOU ZHOU

Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD

Journal of hepatology
2017 | Journal article
Source: Self-asserted source
YOU ZHOU

Mechanisms Underlying Changes in Liver Fat and Insulin Resistance during Overfeeding of Saturated or Unsaturated Fat or Carbohydrate in Humans

DIABETES
2017 | Conference paper
Source: Self-asserted source
YOU ZHOU

Obesity/insulin resistance rather than liver fat increases coagulation factor activities and expression in humans

Thrombosis and haemostasis
2017 | Journal article
Source: Self-asserted source
YOU ZHOU

Predictors of Liver Fat and Stiffness in Non-Alcoholic Fatty Liver Disease (NAFLD)--an 11-Year Prospective Study

Scientific Reports
2017 | Journal article
Source: Self-asserted source
YOU ZHOU

Severe neurodegenerative disease in brothers with homozygous mutation in POLR1A

European Journal of Human Genetics
2017 | Journal article
Source: Self-asserted source
YOU ZHOU

Use of HOMA-IR to diagnose non-alcoholic fatty liver disease: a population-based and inter-laboratory study

Diabetologia
2017 | Journal article
Source: Self-asserted source
YOU ZHOU

A deleterious role for Th9/IL-9 in hepatic fibrogenesis

Scientific Reports
2016 | Journal article
Source: Self-asserted source
YOU ZHOU

Ceramides Dissociate Steatosis and Insulin Resistance in the Human Liver in Non-Alcoholic Fatty Liver Disease

Journal of Hepatology
2016 | Journal article
Source: Self-asserted source
YOU ZHOU

Determination of a Normal value for HOMA-IR and cut-off Value for Non-Alcoholic Fatty Liver Disease

Journal of Hepatology
2016 | Journal article
Source: Self-asserted source
YOU ZHOU

Increased coagulation factor activities and expression in'Metabolic NAFLD'and'PNPLA3 NAFLD'

DIABETOLOGIA
2016 | Conference paper
Source: Self-asserted source
YOU ZHOU

Influence of ethnicity on the accuracy of non-invasive scores predicting non-alcoholic fatty liver disease

PloS one
2016 | Journal article
Source: Self-asserted source
YOU ZHOU

Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin

Scientific reports
2016 | Journal article
Source: Self-asserted source
YOU ZHOU

MicroRNA-192* impairs adipocyte triglyceride storage

Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids
2016 | Journal article
Source: Self-asserted source
YOU ZHOU

Noninvasive detection of nonalcoholic steatohepatitis using clinical markers and circulating levels of lipids and metabolites

Clinical Gastroenterology and Hepatology
2016 | Journal article
Source: Self-asserted source
YOU ZHOU

Novel hepatic microRNAs upregulated in human nonalcoholic fatty liver disease

Physiological reports
2016 | Journal article
Source: Self-asserted source
YOU ZHOU

Phosphorylated IGFBP-1 as a non-invasive predictor of liver fat in NAFLD

Scientific reports
2016 | Journal article
Source: Self-asserted source
YOU ZHOU

The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans

Journal of hepatology
2016 | Journal article
Source: Self-asserted source
YOU ZHOU

Bioactive lipids dissociate steatosis and insulin resistance in the human liver in non-alcoholic fatty liver disease

DIABETOLOGIA
2015 | Conference paper
Source: Self-asserted source
YOU ZHOU

Circulating triacylglycerol signatures and insulin sensitivity in NAFLD associated with the E167K variant in TM6SF2

Journal of hepatology
2015 | Journal article
Source: Self-asserted source
YOU ZHOU

Cripto-1 expression and its prognostic value in human bladder cancer patients

Tumor Biology
2015 | Journal article
Source: Self-asserted source
YOU ZHOU
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