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University of California Berkeley: Berkeley, CA, US

Professor (Molecular and Cell Biology)
Employment
Source: Self-asserted source
David Bilder

Funding (1)

Ancient Origins of the Immune Defense to Tumors

2025-01-01 to 2026-12-31 | Grant
American Cancer Society (Atlanta, US)
GRANT_NUMBER:

DBG-24-1322649-01-IBCD
Source: check_circle
American Cancer Society - ProposalCentral

Works (50 of 68)

Items per page:
Page 1 of 2

Systemic coagulopathy promotes host lethality in a new Drosophila tumor model.

Current biology : CB
2023-06-23 | Journal article
DOI: 10.1016/j.cub.2023.05.071
PMID: 37354901
Contributors: Hsi TC; Ong KL; Sepers JJ; Jung Kim; Bilder D
Source: Self-asserted source
David Bilder

Specialized cells that sense tissue mechanics to regulate Drosophila morphogenesis.

Developmental cell
2023-01 | Journal article
DOI: 10.1016/j.devcel.2023.01.004
PMID: 36708706
Contributors: Ku HY; Harris LK; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

PTP10D-mediated cell competition is not obligately required for elimination of polarity-deficient clones.

Biology open
2022-11 | Journal article
DOI: 10.1242/bio.059525
PMID: 36355597
PMC: PMC9672856
Contributors: Gerlach SU; de Vreede G; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Minimal functional domains of the core polarity regulator Dlg.

Biology open
2022-07 | Journal article
DOI: 10.1242/bio.059408
PMID: 35722710
PMC: PMC9346270
Contributors: Khoury MJ; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Epithelial monitoring through ligand-receptor segregation ensures malignant cell elimination.

Science (New York, N.Y.)
2022-04 | Journal article
DOI: 10.1126/science.abl4213
PMID: 35420935
PMC: PMC9197687
Contributors: de Vreede G; Gerlach SU; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Evidence for a nuclear role for <i>Drosophila</i> Dlg as a regulator of the NURF complex.

Molecular biology of the cell
2021-09 | Journal article
DOI: 10.1091/mbc.e21-04-0187
PMID: 34495684
PMC: PMC8693970
Contributors: Sharp KA; Khoury MJ; Wirtz-Peitz F; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Tumor-induced disruption of the blood-brain barrier promotes host death.

Developmental cell
2021-09 | Journal article
DOI: 10.1016/j.devcel.2021.08.010
PMID: 34496290
PMC: PMC8511098
Contributors: Kim J; Chuang HC; Wolf NK; Nicolai CJ; Raulet DH; Saijo K; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Tumour-host interactions through the lens of Drosophila.

Nature reviews. Cancer
2021-08 | Journal article
DOI: 10.1038/s41568-021-00387-5
PMID: 34389815
PMC: PMC8669834
Contributors: Bilder D; Ong K; Hsi TC; Adiga K; Kim J
Source: Self-asserted source
David Bilder via Europe PubMed Central

Distinct activities of Scrib module proteins organize epithelial polarity.

Proceedings of the National Academy of Sciences of the United States of America
2020-05 | Journal article
DOI: 10.1073/pnas.1918462117
PMID: 32414916
PMC: PMC7260944
Contributors: Khoury MJ; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Extracellular matrix stiffness cues junctional remodeling for 3D tissue elongation.

Nature communications
2019-07 | Journal article
DOI: 10.1038/s41467-019-10874-x
PMID: 31350387
PMC: PMC6659696
Contributors: Chen DY; Crest J; Streichan SJ; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

A Drosophila Tumor Suppressor Gene Prevents Tonic TNF Signaling through Receptor N-Glycosylation.

Developmental cell
2018-06 | Journal article
DOI: 10.1016/j.devcel.2018.05.012
PMID: 29870719
PMC: PMC5995582
Contributors: de Vreede G; Morrison HA; Houser AM; Boileau RM; Andersen D; Colombani J; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Mechanical stress regulates insulin sensitivity through integrin-dependent control of insulin receptor localization.

Genes & development
2018-01 | Journal article
DOI: 10.1101/gad.305870.117
PMID: 29440263
PMC: PMC5830928
Contributors: Kim J; Bilder D; Neufeld TP
Source: Self-asserted source
David Bilder via Europe PubMed Central

A Cell Migration Tracking Tool Supports Coupling of Tissue Rotation to Elongation.

Cell reports
2017-10 | Journal article
DOI: 10.1016/j.celrep.2017.09.083
PMID: 29045826
PMC: PMC5661965
Contributors: Chen DY; Crest J; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Taking Stock of the <i>Drosophila</i> Research Ecosystem.

Genetics
2017-07 | Journal article
DOI: 10.1534/genetics.117.202390
PMID: 28684603
PMC: PMC5500126
Contributors: Bilder D; Irvine KD
Source: Self-asserted source
David Bilder via Europe PubMed Central

Organ sculpting by patterned extracellular matrix stiffness.

eLife
2017-06 | Journal article
DOI: 10.7554/elife.24958
PMID: 28653906
PMC: PMC5503509
Contributors: Crest J; Diz-Muñoz A; Chen DY; Fletcher DA; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Microenvironmental autophagy promotes tumour growth.

Nature
2017-01 | Journal article
DOI: 10.1038/nature20815
PMID: 28077876
PMC: PMC5612666
Contributors: Katheder NS; Khezri R; O'Farrell F; Schultz SW; Jain A; Rahman MM; Schink KO; Theodossiou TA; Johansen T; Juhász G et al.
Source: Self-asserted source
David Bilder via Europe PubMed Central

The Maturation of Development.

Developmental cell
2016-09 | Journal article
DOI: 10.1016/j.devcel.2016.09.010
PMID: 27676426
PMC: PMC5523963
Contributors: Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Symmetry Breaking in an Edgeless Epithelium by Fat2-Regulated Microtubule Polarity.

Cell reports
2016-04 | Journal article
DOI: 10.1016/j.celrep.2016.04.014
PMID: 27134170
PMC: PMC4864504
Contributors: Chen DY; Lipari KR; Dehghan Y; Streichan SJ; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Malignant Drosophila tumors interrupt insulin signaling to induce cachexia-like wasting.

Developmental cell
2015-04 | Journal article
DOI: 10.1016/j.devcel.2015.03.001
PMID: 25850672
PMC: PMC4390765
Contributors: Figueroa-Clarevega A; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

The transcriptional response to tumorigenic polarity loss in Drosophila.

eLife
2015-02 | Journal article
DOI: 10.7554/elife.03189
PMID: 25719210
PMC: PMC4369581
Contributors: Bunker BD; Nellimoottil TT; Boileau RM; Classen AK; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

The F-box protein Slmb restricts the activity of aPKC to polarize epithelial cells.

Development (Cambridge, England)
2014-08 | Journal article
DOI: 10.1242/dev.109694
PMID: 25053431
PMC: PMC4197664
Contributors: Skwarek LC; Windler SL; de Vreede G; Rogers GC; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

The Scribble module regulates retromer-dependent endocytic trafficking during epithelial polarization.

Development (Cambridge, England)
2014-07 | Journal article
DOI: 10.1242/dev.105403
PMID: 25005475
PMC: PMC4197622
Contributors: de Vreede G; Schoenfeld JD; Windler SL; Morrison H; Lu H; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Multiple functions of the SNARE protein Snap29 in autophagy, endocytic, and exocytic trafficking during epithelial formation in Drosophila.

Autophagy
2014-01 | Journal article
DOI: 10.4161/15548627.2014.981913
PMID: 25551675
PMC: PMC4502674
Contributors: Morelli E; Ginefra P; Mastrodonato V; Beznoussenko GV; Rusten TE; Bilder D; Stenmark H; Mironov AA; Vaccari T
Source: Self-asserted source
David Bilder via Europe PubMed Central

Beyond the niche: tissue-level coordination of stem cell dynamics.

Annual review of cell and developmental biology
2013-08 | Journal article
DOI: 10.1146/annurev-cellbio-101512-122319
PMID: 23937350
PMC: PMC3897713
Contributors: O'Brien LE; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

SCFSlimb ubiquitin ligase suppresses condensin II-mediated nuclear reorganization by degrading Cap-H2.

The Journal of cell biology
2013-03 | Journal article
DOI: 10.1083/jcb.201207183
PMID: 23530065
PMC: PMC3613687
Contributors: Buster DW; Daniel SG; Nguyen HQ; Windler SL; Skwarek LC; Peterson M; Roberts M; Meserve JH; Hartl T; Klebba JE et al.
Source: Self-asserted source
David Bilder via Europe PubMed Central

A screen for round egg mutants in Drosophila identifies tricornered, furry, and misshapen as regulators of egg chamber elongation.

G3 (Bethesda, Md.)
2012-03 | Journal article
DOI: 10.1534/g3.111.001677
PMID: 22413091
PMC: PMC3291507
Contributors: Horne-Badovinac S; Hill J; Gerlach G; Menegas W; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Expanding the morphogenetic repertoire: perspectives from the Drosophila egg.

Developmental cell
2012-01 | Journal article
DOI: 10.1016/j.devcel.2011.12.003
PMID: 22264728
PMC: PMC3266552
Contributors: Bilder D; Haigo SL
Source: Self-asserted source
David Bilder via Europe PubMed Central

Altered modes of stem cell division drive adaptive intestinal growth.

Cell
2011-10 | Journal article
DOI: 10.1016/j.cell.2011.08.048
PMID: 22036568
PMC: PMC3246009
Contributors: O'Brien LE; Soliman SS; Li X; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

David Bilder: Getting to know epithelia inside and out. Interviewed by Caitlin Sedwick.

The Journal of cell biology
2011-06 | Journal article
DOI: 10.1083/jcb.1936pi
PMID: 21670209
PMC: PMC3115797
Contributors: Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

The functions of auxilin and Rab11 in Drosophila suggest that the fundamental role of ligand endocytosis in notch signaling cells is not recycling.

PloS one
2011-03 | Journal article
DOI: 10.1371/journal.pone.0018259
PMID: 21448287
PMC: PMC3063240
Contributors: Banks SM; Cho B; Eun SH; Lee JH; Windler SL; Xie X; Bilder D; Fischer JA
Source: Self-asserted source
David Bilder via Europe PubMed Central

Global tissue revolutions in a morphogenetic movement controlling elongation.

Science (New York, N.Y.)
2011-01 | Journal article
DOI: 10.1126/science.1199424
PMID: 21212324
PMC: PMC3153412
Contributors: Haigo SL; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor.

Development (Cambridge, England)
2010-06 | Journal article
DOI: 10.1242/dev.045484
PMID: 20460366
PMC: PMC2867318
Contributors: Vaccari T; Duchi S; Cortese K; Tacchetti C; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Polarity and endocytosis: reciprocal regulation.

Trends in cell biology
2010-05 | Journal article
DOI: 10.1016/j.tcb.2010.04.003
PMID: 20493706
PMC: PMC2917511
Contributors: Shivas JM; Morrison HA; Bilder D; Skop AR
Source: Self-asserted source
David Bilder via Europe PubMed Central

Endocytic internalization routes required for delta/notch signaling.

Current biology : CB
2010-03 | Journal article
DOI: 10.1016/j.cub.2010.01.049
PMID: 20226669
PMC: PMC2845733
Contributors: Windler SL; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling.

Nature genetics
2009-09 | Journal article
DOI: 10.1038/ng.445
PMID: 19749759
PMC: PMC2782793
Contributors: Classen AK; Bunker BD; Harvey KF; Vaccari T; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants.

Journal of cell science
2009-07 | Journal article
DOI: 10.1242/jcs.046391
PMID: 19571114
PMC: PMC2704878
Contributors: Vaccari T; Rusten TE; Menut L; Nezis IP; Brech A; Stenmark H; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

At the crossroads of polarity, proliferation and apoptosis: the use of Drosophila to unravel the multifaceted role of endocytosis in tumor suppression.

Molecular oncology
2009-06 | Journal article
DOI: 10.1016/j.molonc.2009.05.005
PMID: 19560990
PMC: PMC2755045
Contributors: Vaccari T; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Endocytic regulation of Notch signaling.

Current opinion in genetics & development
2009-05 | Journal article
DOI: 10.1016/j.gde.2009.04.005
PMID: 19447603
PMC: PMC2731830
Contributors: Fortini ME; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Quantitative analysis of epithelial morphogenesis in Drosophila oogenesis: New insights based on morphometric analysis and mechanical modeling.

Developmental biology
2009-05 | Journal article
DOI: 10.1016/j.ydbio.2009.04.028
PMID: 19409378
PMC: PMC3145632
Contributors: Kolahi KS; White PF; Shreter DM; Classen AK; Bilder D; Mofrad MR
Source: Self-asserted source
David Bilder via Europe PubMed Central

Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45.

Molecular biology of the cell
2008-08 | Journal article
DOI: 10.1091/mbc.e08-07-0716
PMID: 18685079
PMC: PMC2555928
Contributors: Morrison HA; Dionne H; Rusten TE; Brech A; Fisher WW; Pfeiffer BD; Celniker SE; Stenmark H; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Endosomal entry regulates Notch receptor activation in Drosophila melanogaster.

The Journal of cell biology
2008-02 | Journal article
DOI: 10.1083/jcb.200708127
PMID: 18299346
PMC: PMC2265571
Contributors: Vaccari T; Lu H; Kanwar R; Fortini ME; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Dynein regulates epithelial polarity and the apical localization of stardust A mRNA.

PLoS genetics
2008-01 | Journal article
DOI: 10.1371/journal.pgen.0040008
PMID: 18208331
PMC: PMC2213700
Contributors: Horne-Badovinac S; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

A mosaic genetic screen for Drosophila neoplastic tumor suppressor genes based on defective pupation.

Genetics
2007-10 | Journal article
DOI: 10.1534/genetics.107.078360
PMID: 17947427
PMC: PMC2147992
Contributors: Menut L; Vaccari T; Dionne H; Hill J; Wu G; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

ESCRTs and Fab1 regulate distinct steps of autophagy.

Current biology : CB
2007-10 | Journal article
DOI: 10.1016/j.cub.2007.09.032
PMID: 17935992
Contributors: Rusten TE; Vaccari T; Lindmo K; Rodahl LM; Nezis IP; Sem-Jacobsen C; Wendler F; Vincent JP; Brech A; Bilder D et al.
Source: Self-asserted source
David Bilder via Europe PubMed Central

Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila.

Annual review of genetics
2006-01 | Journal article
DOI: 10.1146/annurev.genet.39.073003.100738
PMID: 16872256
Contributors: Hariharan IK; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Emerging from the fog: hypotheses and paradigms in developmental biology--the Society for Developmental Biology 2005 Annual Meeting Report.

Developmental biology
2005-12 | Journal article
DOI: 10.1016/j.ydbio.2005.10.039
PMID: 16337185
Contributors: Sun X; Barolo S; Bilder D; Montgomery M; Sinha N
Source: Self-asserted source
David Bilder via Europe PubMed Central

The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking.

Developmental cell
2005-11 | Journal article
DOI: 10.1016/j.devcel.2005.09.019
PMID: 16256743
Contributors: Vaccari T; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Endocytic control of epithelial polarity and proliferation in Drosophila.

Nature cell biology
2005-10 | Journal article
DOI: 10.1038/ncb1324
PMID: 16258546
Contributors: Lu H; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Mass transit: epithelial morphogenesis in the Drosophila egg chamber.

Developmental dynamics : an official publication of the American Association of Anatomists
2005-03 | Journal article
DOI: 10.1002/dvdy.20286
PMID: 15704134
Contributors: Horne-Badovinac S; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central

Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble.

The Journal of cell biology
2004-12 | Journal article
DOI: 10.1083/jcb.200407158
PMID: 15611336
PMC: PMC2172630
Contributors: Zeitler J; Hsu CP; Dionne H; Bilder D
Source: Self-asserted source
David Bilder via Europe PubMed Central
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Page 1 of 2

Peer review (1 review for 1 publication/grant)

Review activity for American Heart Association (1)
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