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United States

Activities

Employment (2)

Memorial Sloan Kettering Cancer Center: New York, US

2022-09-01 to present | Director, Clinical NGS (Department of Pathology and Laboratory Medicine)
Employment
Source: Self-asserted source
Brian Loomis

Sloan Kettering Institute: New York, NY, US

2018-01-15 to present | Mgr.,CMO Technology Innovation (Cmo operation)
Employment
Source: check_circle
Memorial Sloan Kettering Cancer Center

Works (37)

Data from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

Data from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

Supplemental Figure 1 from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

Supplemental Figure 1 from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

Supplemental Figure 2 from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

Supplemental Figure 2 from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

Supplemental Figure 3 from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

Supplemental Figure 3 from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

Supplemental Figure 4 from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

Supplemental Figure 4 from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

Supplemental Methods 1 from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

Supplemental Methods 1 from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

Supplemental Methods 2 from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

Supplemental Methods 2 from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

Supplemental Tables from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

Supplemental Tables from Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

2023-03-31 | Preprint
Contributors: Jason C. Chang; Michael Offin; Christina Falcon; David Brown; Brian R. Houck-Loomis; Fanli Meng; Vasilisa A. Rudneva; Helen H. Won; Sharon Amir; Joseph Montecalvo et al.
Source: check_circle
Crossref

ERα-LBD, an isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance

npj Breast Cancer
2022-08-23 | Journal article
Contributors: Antonio Strillacci; Pasquale Sansone; Vinagolu K. Rajasekhar; Mesruh Turkekul; Vitaly Boyko; Fanli Meng; Brian Houck-Loomis; David Brown; Michael F. Berger; Ronald C. Hendrickson et al.
Source: check_circle
Crossref

Multiomic Analysis of Lung Tumors Defines Pathways Activated in Neuroendocrine Transformation.

Cancer discovery
2021-12-01 | Journal article
Contributors: Brian Loomis
Source: Self-asserted source
Brian Loomis

Diverse alterations associated with resistance to KRAS(G12C) inhibition.

Nature
2021-11-10 | Journal article
Contributors: Brian Loomis
Source: Self-asserted source
Brian Loomis

Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation.

Journal of hematology & oncology
2021-10-16 | Journal article
Contributors: Brian Loomis
Source: Self-asserted source
Brian Loomis

Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS.

Nature communications
2021-06-18 | Journal article
Contributors: Brian Loomis
Source: Self-asserted source
Brian Loomis

Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes.

Clinical cancer research : an official journal of the American Association for Cancer Research
2021-05-04 | Journal article
Contributors: Brian Loomis
Source: Self-asserted source
Brian Loomis
grade
Preferred source (of 2)‎

Developing Quality Programs for Cell-Free DNA (cfDNA) Extraction from Peripheral Blood.

The journal of applied laboratory medicine
2020-07-01 | Journal article
Source: Self-asserted source
Brian Loomis

Effect of Osimertinib and Bevacizumab on Progression-Free Survival for Patients With Metastatic EGFR-Mutant Lung Cancers: A Phase 1/2 Single-Group Open-Label Trial.

JAMA oncology
2020-07-01 | Journal article
Source: Self-asserted source
Brian Loomis

Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring.

Nature medicine
2020-06-01 | Journal article
Source: Self-asserted source
Brian Loomis

Resistance to TRK inhibition mediated by convergent MAPK pathway activation

Nature Medicine
2019-09-01 | Journal article
Contributors: Cocco, E.; Schram, A. M.; Kulick, A.; Misale, S.; Won, H. H.; Yaeger, R.; Razavi, P.; Ptashkin, R.; Hechtman, J. F.; Toska, E. et al.
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Memorial Sloan Kettering Cancer Center

A bioinformatics framework for high-sensitivity detection and monitoring of oncogenic gene fusions in plasma cfDNA

Cancer Research
2019-07-01 | Conference abstract
SOURCE-WORK-ID:

156017

Contributors: Patel, J.; Hasan, M.; Meng, F.; Jing, X.; Tam, G.; Johnson, I.; Zheng, Y.; Bandlamudi, C.; Stewart, C.; Won, H. et al.
Source: check_circle
Memorial Sloan Kettering Cancer Center

Tracking minimal residual disease in post-operative cell-free DNA using MSK-ACCESS

Cancer Research
2019-07-01 | Conference abstract
SOURCE-WORK-ID:

156058

Contributors: Hasan, M. M.; Patel, J.; Johnson, I.; Meng, F.; Tam, G. K.; Jing, X.; Yang, J. L.; Brannon, A. R.; Gowtham, J.; Stephens, D. P. et al.
Source: check_circle
Memorial Sloan Kettering Cancer Center

Non-invasive detection of acquired resistance to FGFR inhibition in patients with cholangiocarcinoma harboring FGFR2 alterations

Journal of Clinical Oncology
2019-05-20 | Conference abstract
SOURCE-WORK-ID:

156482

Contributors: Varghese, A. M.; Patel, J. A. A.; Janjigian, Y. Y.; Meng, F.; Selcuklu, S. D.; Zimel, C.; Hyman, D. M.; Iyer, G.; Houck-Loomis, B.; Abou-Alfa, G. K. et al.
Source: check_circle
Memorial Sloan Kettering Cancer Center

Clinical validation of MSK-ACCESS: An ultrasensitive next-generation sequencing assay for liquid biopsies in the clinic

Journal of Molecular Diagnostics
2018-11-01 | Conference abstract
SOURCE-WORK-ID:

135967

Contributors: Brannon, A.; Jayakumaran, G.; Patel, J.; Johnson, I.; Diosdado, M.; Hasan, M.; Perera, D.; Meng, F.; Jing, X.; Reichel, J. et al.
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Memorial Sloan Kettering Cancer Center

Cell “hashing” with barcoded antibodies enables multiplexing and doublet detection for single cell genomics

2017-12-21 | Other
Contributors: Marlon Stoeckius; Shiwei Zheng; Brian Houck-Loomis; Stephanie Hao; Bertrand Z. Yeung; Peter Smibert; Rahul Satija
Source: check_circle
Crossref

Simultaneous epitope and transcriptome measurement in single cells

Nature Methods
2017-09 | Journal article
Part of ISSN: 1548-7091
Part of ISSN: 1548-7105
Contributors: Brian Loomis
Source: Self-asserted source
Brian Loomis
grade
Preferred source (of 2)‎

Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries.

Nature methods
2014-07-06 | Journal article
Source: Self-asserted source
Brian Loomis

Histone H3K27 trimethylation inhibits H3 binding and function of SET1-like H3K4 methyltransferase complexes.

Molecular and Cellular Biology
2013-10-14 | Journal article
Source: Self-asserted source
Brian Loomis

Large ribosomal protein 4 increases efficiency of viral recoding sequences.

Journal of virology
2012-06-20 | Journal article
Source: Self-asserted source
Brian Loomis

An equilibrium-dependent retroviral mRNA switch regulates translational recoding.

Nature
2011-11-27 | Journal article
Source: Self-asserted source
Brian Loomis

The C-terminal portion of the Hrs protein interacts with Tsg101 and interferes with human immunodeficiency virus type 1 Gag particle production.

Journal of virology
2006-12-20 | Journal article
Source: Self-asserted source
Brian Loomis

Peer review (1 review for 1 publication/grant)

Review activity for Nature genetics. (1)