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Works (13)

Consequences of a telomerase-related fitness defect and chromosome substitution technology in yeast synIX strains

Cell Genomics
2023-11 | Journal article
Part of ISSN: 2666-979X
Contributors: Laura McCulloch; Vijayan Sambasivam; Amanda L. Hughes; Narayana Annaluru; Sivaprakash Ramalingam; Viola Fanfani; Evgenii Lobzaev; Leslie A. Mitchell; Jitong Cai; Hua Jiang et al.
Source: Self-asserted source
Amanda Hughes

Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions

Cell
2023-11 | Journal article
Part of ISSN: 0092-8674
Contributors: Yu Zhao; Camila Coelho; Amanda L. Hughes; Luciana Lazar-Stefanita; Sandy Yang; Aaron N. Brooks; Roy S.K. Walker; Weimin Zhang; Stephanie Lauer; Cindy Hernandez et al.
Source: Self-asserted source
Amanda Hughes

Transcriptional neighborhoods regulate transcript isoform lengths and expression levels

Science
2022-03-04 | Journal article
Contributors: Aaron N. Brooks; Amanda L. Hughes; Sandra Clauder-Münster; Leslie A. Mitchell; Jef D. Boeke; Lars M. Steinmetz
Source: check_circle
Crossref

Histone exchange is associated with activator function at transcribed promoters and with repression at histone loci

Science Advances
2020-09-04 | Journal article
Part of ISSN: 2375-2548
Source: Self-asserted source
Amanda Hughes

Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome

eLife
2018-08-06 | Journal article
Contributors: Ramasubramanian Sundaramoorthy; Amanda L Hughes; Hassane El-Mkami; David G Norman; Helder Ferreira; Tom Owen-Hughes
Source: check_circle
Crossref

Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes

eLife
2017-03-23 | Journal article
Part of ISSN: 2050-084X
Source: Self-asserted source
Amanda Hughes

Deciphering Subunit-Specific Functions within SWI/SNF Complexes

Cell Reports
2017-02 | Journal article
Part of ISSN: 2211-1247
Source: Self-asserted source
Amanda Hughes

Genome-wide histone modification patterns in<i>Kluyveromyces Lactis</i>reveal evolutionary adaptation of a heterochromatin-associated mark

2016-02-15 | Preprint
Contributors: Angela Bean; Assaf Weiner; Amanda Hughes; Eyal Itskovits; Nir Friedman; Oliver J. Rando
Source: Self-asserted source
Amanda Hughes

Comparative Genomics Reveals Chd1 as a Determinant of Nucleosome Spacing in Vivo

G3 Genes|Genomes|Genetics
2015-09-01 | Journal article
Part of ISSN: 2160-1836
Source: Self-asserted source
Amanda Hughes

Mechanisms Underlying Nucleosome Positioning In Vivo

Annual Review of Biophysics
2014-05-06 | Journal article
Part of ISSN: 1936-122X
Part of ISSN: 1936-1238
Source: Self-asserted source
Amanda Hughes

A Functional Evolutionary Approach to Identify Determinants of Nucleosome Positioning: A Unifying Model for Establishing the Genome-wide Pattern

Molecular Cell
2012-10 | Journal article
Part of ISSN: 1097-2765
Source: Self-asserted source
Amanda Hughes

High-resolution nucleosome mapping reveals transcription-dependent promoter packaging

Genome Research
2010-01 | Journal article
Part of ISSN: 1088-9051
Source: Self-asserted source
Amanda Hughes

Chromatin 'programming' by sequence - is there more to the nucleosome code than %GC?

Journal of Biology
2009 | Journal article
Part of ISSN: 1475-4924
Source: Self-asserted source
Amanda Hughes