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Development and validation of pFIB scores for exclusion of significant liver fibrosis in pediatric MASLD

Hepatology
2025-04 | Journal article
DOI: 10.1097/HEP.0000000000001016
Contributors: Sander Lefere; Antonella Mosca; Christian Hudert; Ellen Dupont; Emer Fitzpatrick; Eirini Kyrana; Anil Dhawan; Laura Kalveram; Andrea Pietrobattista; Anja Geerts et al.
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Reply: Can pFIB scores reliably exclude significant liver fibrosis in pediatric MASLD?

Hepatology
2025-04 | Journal article
DOI: 10.1097/HEP.0000000000001069
Contributors: Sander Lefere; Antonella Mosca; Christian Hudert; Ellen Dupont; Emer Fitzpatrick; Eirini Kyrana; Anil Dhawan; Laura Kalveram; Andrea Pietrobattista; Anja Geerts et al.
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Reply: Development and validation of pFIB scores for exclusion of significant liver fibrosis in pediatric MASLD

Hepatology
2025-04 | Journal article
DOI: 10.1097/HEP.0000000000001088
Contributors: Sander Lefere; Antonella Mosca; Christian Hudert; Ellen Dupont; Emer Fitzpatrick; Eirini Kyrana; Anil Dhawan; Laura Kalveram; Andrea Pietrobattista; Anja Geerts et al.
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Prior metabolic and bariatric surgery is an independent determinant of severity of decompensation in alcohol‐associated liver disease

United European Gastroenterology Journal
2024-12 | Journal article
DOI: 10.1002/ueg2.12642
Contributors: Louis Onghena; Yves van Nieuwenhove; Hans Van Vlierberghe; Lindsey Devisscher; Sarah Raevens; Xavier Verhelst; Sander Lefere; Anja Geerts
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Bariatric surgery post-liver transplantation: A Belgian nationwide study

Liver Transplantation
2024-10 | Journal article
DOI: 10.1097/LVT.0000000000000372
Contributors: Louis Onghena; Anja Geerts; Frederik Berrevoet; Jacques Pirenne; Jef Verbeek; Eliano Bonaccorsi-Riani; Geraldine Dahlqvist; Luisa Vonghia; Olivier Detry; Jean Delwaide et al.
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Validation of a glycomics-based test associated with risk of HCC development in cirrhosis

2024-02-28 | Preprint
DOI: 10.1101/2024.02.27.24303387
Contributors: Xavier Verhelst; Leander Meuris; Roos Colman; Anja Geerts; Annelies Van Hecke; Hans Van Vlierberghe; Nico Callewaert
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Patients hospitalized with alcohol‐related liver disease and prior bariatric surgery are more prone to develop acute‐on‐chronic liver failure

Liver International
2023-12 | Journal article
DOI: 10.1111/liv.15726
Contributors: Louis Onghena; Yves Van Nieuwenhove; Laurissa Demeulenaere; Lindsey Devisscher; Xavier Verhelst; Helena Degroote; Sarah Raevens; Hans Van Vlierberghe; Sander Lefere; Anja Geerts
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Meta‐analysis: The impact of light‐to‐moderate alcohol consumption on progressive non‐alcoholic fatty liver disease

Alimentary Pharmacology & Therapeutics
2023-04 | Journal article
DOI: 10.1111/apt.17388
Contributors: Louise Magherman; Robbe Van Parys; Nele S. Pauwels; Xavier Verhelst; Lindsey Devisscher; Hans Van Vlierberghe; Anja Geerts; Sander Lefere
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Bariatric surgery for non-alcoholic fatty liver disease: Indications and post-operative management

Clinical and Molecular Hepatology
2023-02-28 | Journal article
DOI: 10.3350/cmh.2022.0373
Contributors: Anja Geerts; Sander Lefere
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Rare case of ascites several years after liver transplantation

Gastroenterology Report
2022-01-25 | Journal article
DOI: 10.1093/gastro/goac076
Contributors: Liesbeth Deroo; Anne Hoorens; Xavier Verhelst; Helena Degroote; Hans Van Vlierberghe; Anja Geerts
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Characterization of the inflammatory microenvironment and hepatic macrophage subsets in experimental hepatocellular carcinoma models

Oncotarget
2021 | Journal article | Author
DOI: 10.18632/oncotarget.27906
HANDLE: 1854/LU-8731581
Contributors: Helena Degroote; Sander Lefere; Vandierendonck, Astrid; Vanderborght, Bart; Meese, Tim; Filip Van Nieuwerburgh; Xavier Verhelst; anja geerts; Hans Van Vlierberghe; Lindsey Devisscher
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Ghent University Academic Bibliography

Intensive lifestyle management improves steatosis and fibrosis in pediatric non-alcoholic fatty liver disease

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
2021 | Journal article | Author
DOI: 10.1016/j.cgh.2021.11.039
HANDLE: 1854/LU-8728559
Contributors: Sander Lefere; Dupont, Ellen; ann De Guchtenaere; Stephanie Van Biervliet; Saskia Vande Velde; Xavier Verhelst; Lindsey Devisscher; Hans Van Vlierberghe; anja geerts; Ruth De Bruyne
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Ghent University Academic Bibliography

Maternal and perinatal risk factors for pediatric nonalcoholic fatty liver disease : a systematic review

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
2021 | Journal article | Author
DOI: 10.1016/j.cgh.2021.04.014
HANDLE: 1854/LU-8730156
Contributors: Querter, Ilya; Nele S. Pauwels; Ruth De Bruyne; Dupont, Ellen; Xavier Verhelst; Lindsey Devisscher; Hans Van Vlierberghe; anja geerts; Sander Lefere
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Ghent University Academic Bibliography

Metallothioneins alter macrophage phenotype and represent novel therapeutic targets for acetaminophen-induced liver injury

JOURNAL OF LEUKOCYTE BIOLOGY
2021 | Journal article | Author
DOI: 10.1002/JLB.3A0820-527R
HANDLE: 1854/LU-8703767
Contributors: Lindsey Devisscher; Sanne Van Campenhout; Sander Lefere; Raevens, Sarah; Laurentijn Tilleman; Filip Van Nieuwerburgh; Van Eeckhoutte, Hannelore P.; Anne Hoorens; Lynes, Michael A.; anja geerts et al.
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Ghent University Academic Bibliography

NOX1 inhibition attenuates the development of a pro‐tumorigenic environment in experimental hepatocellular carcinoma

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
2021 | Journal article | Author
DOI: 10.1186/s13046-021-01837-6
HANDLE: 1854/LU-8696583
Contributors: Aster Vandierendonck; Helena Degroote; Vanderborght, Bart; Xavier Verhelst; anja geerts; Lindsey Devisscher; Hans Van Vlierberghe
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Reply

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
2021 | Journal article | Author
DOI: 10.1016/j.cgh.2021.09.011
HANDLE: 1854/LU-8730163
Contributors: Querter, Ilya; Ruth De Bruyne; anja geerts; Sander Lefere
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Ghent University Academic Bibliography

Serum glycomics on postoperative day 7 are associated with graft loss within 3 months after liver transplantation regardless of early allograft dysfunction

TRANSPLANTATION
2021 | Journal article | Author
DOI: 10.1097/tp.0000000000003567
HANDLE: 1854/LU-8689670
Contributors: Xavier Verhelst; anja geerts; Roos Colman; Vanlander, Arnaud; Helena Degroote; de Carvalho, Luis Abreu; Leander Meuris; Frederik Berrevoet; Rogiers, Xavier; Nico Callewaert et al.
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Ghent University Academic Bibliography

The neurogliovascular unit in hepatic encephalopathy

JHEP REPORTS
2021 | Journal article | Author
DOI: 10.1016/j.jhepr.2021.100352
HANDLE: 1854/LU-8725158
Contributors: Wouter Claeys; Van Hoecke, Lien; Sander Lefere; anja geerts; Xavier Verhelst; Hans Van Vlierberghe; Helena Degroote; Lindsey Devisscher; Vandenbroucke Roosmarijn; Van Steenkiste, Christophe
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Ghent University Academic Bibliography

The utility of biomarkers in prognosis assessment of patients with acute liver failure

HEPATOLOGY RESEARCH
2021 | Journal article | Author
DOI: 10.1111/hepr.13668
HANDLE: 1854/LU-8711437
Contributors: De Clercq, Pauline; anja geerts; Hans Van Vlierberghe; Xavier Verhelst
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Bariatric surgery and the liver—Mechanisms, benefits, and risks

Obesity Reviews
2021-09 | Journal article
DOI: 10.1111/obr.13294
Contributors: Sander Lefere; Louis Onghena; Aude Vanlander; Yves van Nieuwenhove; Lindsey Devisscher; Anja Geerts
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Health status of patients with autoimmune hepatitis is not affected by the SARS-CoV-2 outbreak in Flanders, Belgium

Journal of Hepatology
2021-01 | Journal article
DOI: 10.1016/j.jhep.2020.08.035
Contributors: Xavier Verhelst; Nicky Somers; Anja Geerts; Helena Degroote; Hans Van Vlierberghe
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A murine model of hepatic encephalopathy : validation and neurobehavioral testing

2020 | Conference abstract | Author
HANDLE: 1854/LU-8687591
Contributors: Wouter Claeys; anja geerts; Sander Lefere; Hans Van Vlierberghe; Van Imschoot, Griet; Van Wonterghem, Elien; Vandenbroucke Roosmarijn; Van Steenkiste, Christophe
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Ghent University Academic Bibliography

Angiogenesis in the progression of non-alcoholic fatty liver disease

ACTA GASTRO-ENTEROLOGICA BELGICA
2020 | Journal article | Author
HANDLE: 1854/LU-8711376
Contributors: Sander Lefere; Lindsey Devisscher; anja geerts
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Ghent University Academic Bibliography

Charting extracellular transcriptomes in the human biofluid RNA atlas

CELL REPORTS
2020 | Journal article | Author
DOI: 10.1016/j.celrep.2020.108552
HANDLE: 1854/LU-8687628
Contributors: Hulstaert, Eva; Annelien Morlion; Francisco Avila Cobos; Kimberly Verniers; Nuytens, Justine; Vanden Eynde, Eveline; Yigit, Nurten; JASPER ANCKAERT; anja geerts; Hindryckx, Pieter et al.
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Ghent University Academic Bibliography

Effect of isoform-specific HIF-1α and HIF-2α antisense oligonucleotides on tumorigenesis, inflammation and fibrosis in a hepatocellular carcinoma mouse model

ONCOTARGET
2020 | Journal article | Author
DOI: 10.18632/oncotarget.27830
HANDLE: 1854/LU-8696576
Contributors: Vanderborght, Bart; De Muynck, Kevin; Sander Lefere; anja geerts; Helena Degroote; Xavier Verhelst; Hans Van Vlierberghe; Lindsey Devisscher
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Ghent University Academic Bibliography

Histologically proven hepatic steatosis associates with lower testosterone levels in men with obesity

ASIAN JOURNAL OF ANDROLOGY
2020 | Journal article | Author
DOI: 10.4103/aja.aja_68_19
HANDLE: 1854/LU-8632980
Contributors: Frederique Van de Velde; Bekaert, Marlies; Anne Hoorens; anja geerts; Guy T'Sjoen; tom fiers; Kaufman, Jean; Van Nieuwenhove, Yves; Bruno Lapauw
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Ghent University Academic Bibliography

Patients with chronic hepatitis C virus infection are at high risk of being lost to follow-up : focused interventions can increase linkage to care

ACTA GASTRO-ENTEROLOGICA BELGICA
2020 | Journal article | Author
HANDLE: 1854/LU-8689365
Contributors: Keymeulen, Hannah; Van de Velde, Hannah; Helena Degroote; anja geerts; Hans Van Vlierberghe; Xavier Verhelst
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Ghent University Academic Bibliography

Up to 50% of portal vein thrombosis remains undiagnosed until liver transplantation

CLINICAL TRANSPLANTATION
2020 | Journal article | Author
DOI: 10.1111/ctr.14107
HANDLE: 1854/LU-8708842
Contributors: Bert, Josephine; anja geerts; Vanlander, Aude; Abreu De Carvalho, Luis; Helena Degroote; Frederik Berrevoet; Rogiers, Xavier; Hans Van Vlierberghe; Xavier Verhelst
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Ghent University Academic Bibliography

Angiopoietin-2 promotes pathological angiogenesis and is a therapeutic target in murine nonalcoholic fatty liver disease

HEPATOLOGY
2019 | Journal article | Author
DOI: 10.1002/hep.30294
HANDLE: 1854/LU-8607701
Contributors: Sander Lefere; Frederique Van de Velde; Anne Hoorens; Raevens, Sarah; Sanne Van Campenhout; Aster Vandierendonck; Neyt, Sara; Vandeghinste, Bert; Christian Vanhove; Charlotte Debbaut et al.
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Ghent University Academic Bibliography

Charting extracellular transcriptomes in The Human Biofluid RNA Atlas

bioRxiv
2019 | Journal article | Author
DOI: https://doi.org/10.1101/823369
HANDLE: 1854/LU-8644308
Contributors: Hulstaert, Eva; Annelien Morlion; Francisco Avila Cobos; Kimberly Verniers; Nuytens, Justine; Vanden Eynde, Eveline; Yigit, Nurten; JASPER ANCKAERT; anja geerts; Hindryckx, Pieter et al.
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Ghent University Academic Bibliography
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Combination of sivelestat and N-acetylcysteine alleviates the inflammatory response and exceeds standard treatment for acetaminophen-induced liver injury

JOURNAL OF LEUKOCYTE BIOLOGY
2019 | Journal article | Author
DOI: 10.1002/JLB.5A1119-279R
HANDLE: 1854/LU-8640182
Contributors: Raevens, Sarah; Sanne Van Campenhout; Debacker, Pieter-Jan; Lefere, Sander; Xavier Verhelst; anja geerts; Hans Van Vlierberghe; Colle, Isabelle; Lindsey Devisscher
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Ghent University Academic Bibliography

Insulin resistance associates with hepatic lobular inflammation in subjects with obesity

ENDOCRINE CONNECTIONS
2019 | Journal article | Author
DOI: 10.1530/ec-19-0366
HANDLE: 1854/LU-8632973
Contributors: Frederique Van de Velde; Bekaert, Marlies; anja geerts; Anne Hoorens; Batens, Arsène-Hélène; Shadid, Samiah; Ouwens, Margriet; Van Nieuwenhove, Yves; Bruno Lapauw
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Ghent University Academic Bibliography

Myeloid-specific IRE1 alpha deletion reduces tumour development in a non-alcoholic steatohepatitis-induced hepatocellular carcinoma mouse model

2019 | Conference abstract | Author
DOI: 10.1016/s0618-8278(19)30747-9
HANDLE: 1854/LU-8618487
Contributors: Sanne Van Campenhout; Sander Lefere; Aster Vandierendonck; Xavier Verhelst; anja geerts; Hans Van Vlierberghe; Lindsey Devisscher
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Ghent University Academic Bibliography

Outcome of liver transplantation for hepatopulmonary syndrome : a Eurotransplant experience

EUROPEAN RESPIRATORY JOURNAL
2019 | Journal article | Author
DOI: 10.1183/13993003.01096-2018
HANDLE: 1854/LU-8592227
Contributors: Raevens, Sarah; Rogiers, Xavier; anja geerts; Xavier Verhelst; Samuel, Undine; van Rosmalen, Marieke; Berlakovich, Gabriela; Delwaide, Jean; Detry, Olivier; Lehner, Frank et al.
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Ghent University Academic Bibliography

The human biofluid RNA atlas : expanding the liquid biopsy field beyond the blood stream

2019 | Conference poster | Author
HANDLE: 1854/LU-8611140
Contributors: Hulstaert, Eva; Kimberly Verniers; Nuytens, Justine; Vanden Eynde, Eveline; Yigit, Nurten; JASPER ANCKAERT; anja geerts; Peggy Jacques; Guy Brusselle; Thierry Derveaux et al.
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Ghent University Academic Bibliography

Why pulse oximetry is inaccurate in liver cirrhosis : ancient knowledge

HEPATOLOGY
2019 | Journal article | Author
DOI: 10.1002/hep.30260
HANDLE: 1854/LU-8592369
Contributors: Raevens, Sarah; Isabelle Colle; anja geerts; Hans Van Vlierberghe
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A new 'treatment-response score' for AUTO immune hepatitis is predictive of LONG-TERM event-free survival and overall survival : a multicenter Belgian cohort study

2018 | Conference abstract | Author
HANDLE: 1854/LU-8600516
Contributors: Simoen, Cedric; Schouten, Jeoffrey; Isabelle Colle; van Steenkiste, Christophe; Sermon, Filip; Anne Hoorens; anja geerts; Hans Van Vlierberghe; Xavier Verhelst
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Angiopoietin-2 as therapeutic target for pathological angiogenesis and inflammation in non-alcoholic steatohepatitis

2018 | Conference abstract | Author
DOI: 10.1016/s0168-8278(18)30878-x
HANDLE: 1854/LU-8621098
Contributors: Sander Lefere; Frederique Van de Velde; Raevens, Sarah; Sanne Van Campenhout; Aster Vandierendonck; Neyt, S; Christian Vanhove; Anne Hoorens; Christophe Casteleyn; Xavier Verhelst et al.
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Angiopoietin-2 as therapeutic target for pathological angiogenesis and inflammation in non-alcoholic steatohepatitis

2018 | Conference abstract | Author
HANDLE: 1854/LU-8633522
Contributors: Sander Lefere; Van de Velde, F; Raevens, Sarah; Sanne Van Campenhout; Aster Vandierendonck; Neyt, Sara; Christian Vanhove; Anne Hoorens; CASTELEYN, CHRISTINE; Xavier Verhelst et al.
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Angiopoietin-2 promotes pathological angiogenesis and is a novel therapeutic target in non-alcoholic fatty liver disease

2018 | Conference abstract | Author
HANDLE: 1854/LU-8600513
Contributors: Sander Lefere; Frederique Van de Velde; Anne Hoorens; Raevens, Sarah; Sanne Van Campenhout; Aster Vandierendonck; Neyt, Sara; Vandeghinste, Bert; Christian Vanhove; Charlotte Debbaut et al.
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Clinical burden of hepatitis E virus infection in a tertiary care center in Flanders, Belgium

JOURNAL OF CLINICAL VIROLOGY
2018 | Journal article | Author
DOI: 10.1016/j.jcv.2018.03.004
HANDLE: 1854/LU-8563886
Contributors: Cattoir, Lien; VAN HOECKE, FREDERIK; Tom Van Maerken; Nys, Eline; Ryckaert, Inge; De Boulle, Matthias; anja geerts; Xavier Verhelst; Isabelle Colle; Hutse, Veronik et al.
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Ghent University Academic Bibliography

Cu isotope ratio shifts in common bile duct ligated mice and correlates with the degree of cholestatic-induced liver disease

2018 | Conference poster | Author
DOI: 10.1016/S0168-8278(18)31154-1
HANDLE: 1854/LU-8591942
Contributors: Sanne Van Campenhout; Costas Rodriguez, Marta; Agustina Ari Murti Budi Hastuti; Raevens, Sarah; anja geerts; Xavier Verhelst; Frank Vanhaecke; Hans Van Vlierberghe; Lindsey Devisscher
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Glycome patterns of perfusate in livers before transplantation associate with primary non-function

GASTROENTEROLOGY
2018 | Journal article | Author
DOI: 10.1053/j.gastro.2017.12.027
HANDLE: 1854/LU-8544691
Contributors: Xavier Verhelst; anja geerts; Jochmans, Ina; Vanderschaeghe, Dieter; Paradissis, Agnes; Vanlander, Aude; Frederik Berrevoet; Dahlqvuist, Géraldine; Nevens, Frederik; Pirenne, Jacques et al.
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Hepatic changes in the fontan circulation : identification of liver dysfunction and an attempt to streamline follow-up screening

PEDIATRIC CARDIOLOGY
2018 | Journal article | Author
DOI: 10.1007/s00246-018-1937-1
HANDLE: 1854/LU-8572575
Contributors: Ackerman, Thomas; anja geerts; Hans Van Vlierberghe; Julie De Backer; Katrien François
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Model for end-stage liver disease score and hemodynamic instability as a predictor of poor outcome in early transjugular intrahepatic portosystemic shunt treatment for acute variceal hemorrhage

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
2018 | Journal article | Author
DOI: 10.1097/MEG.0000000000001222
HANDLE: 1854/LU-8571686
Contributors: Hermie, Laurens; Elisabeth Dhondt; Vanlangenhove, Peter; Eric Hoste; anja geerts; Defreyne, Luc
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Placental growth factor inhibition targets pulmonary angiogenesis and represents a therapy for hepatopulmonary syndrome in mice

HEPATOLOGY
2018 | Journal article | Author
DOI: 10.1002/hep.29579
HANDLE: 1854/LU-8539414
Contributors: Raevens, Sarah; anja geerts; Annelies Paridaens; Sander Lefere; Xavier Verhelst; Anne Hoorens; Jo Van Dorpe; Tania Maes; Ken Bracke; Christophe Casteleyn et al.
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Secondary adrenal insufficiency after treatment with budesonide for autoimmune hepatitis

CASE REPORTS IN GASTROENTEROLOGY
2018 | Journal article | Author
DOI: 10.1159/000492204
HANDLE: 1854/LU-8607989
Contributors: De Maeyer, Filip; Bruno Lapauw; Anne Hoorens; anja geerts; Hans Van Vlierberghe; Xavier Verhelst
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The combination of N-acetylcysteine and anti-MT antibodies as novel therapy for acetaminophen-induced liver injury

2018 | Conference abstract | Author
HANDLE: 1854/LU-8633538
Contributors: Lindsey Devisscher; Debby Laukens; Van Eeckhoutte, Hannelore; Raevens, Sarah; Sander Lefere; Anne Hoorens; Xavier Verhelst; Lynes, M; anja geerts; Hans Van Vlierberghe
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A glycomic based serum marker analysed on postoperative day 7 after liver transplantation is an independent predictor of graft and patient survival during the first year after liver transplantation

2017 | Conference abstract | Author
HANDLE: 1854/LU-8538710
Contributors: Xavier Verhelst; anja geerts; Rogiers, Xavier; Vanlander, Aude; Frederik Berrevoet; Nico Callewaert; Troisi, Roberto; Hans Van Vlierberghe
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A glycomic serum marker analysed at one week after liver transplantation is an independent predictor of graft loss during the first year after liver transplantation

2017 | Conference abstract | Author
HANDLE: 1854/LU-8522546
Contributors: Xavier Verhelst; anja geerts; Rogiers, Xavier; Vanlander, Aude; Frederik Berrevoet; Nico Callewaert; Hans Van Vlierberghe
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