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Works (12)

Scalable Synthesis of 6-Chloro-1H-pyrazolo[3,4-b]pyrazine via a Continuous Flow Formylation/Hydrazine Cyclization Cascade

Organic Process Research & Development
2024-07-19 | Journal article
DOI: 10.1021/acs.oprd.4c00047
Contributors: Thomas M. Bass; Daniel Zell; Sean M. Kelly; Thomas C. Malig; José G. Napolitano; Lauren E. Sirois; Chong Han; Francis Gosselin
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Streamlined Synthesis of SHP2 Inhibitor GDC-1971 Enhanced by a Telescoped Schotten-Baumann SNAr and Reactive Crystallization Cascade

Organic Process Research & Development
2024-07-19 | Journal article
DOI: 10.1021/acs.oprd.4c00162
Contributors: Lauren E. Sirois; Nicholas A. White; Jeff Shen; Derek M. Dalton; Daniel Zell; Frédéric St-Jean; Francis Gosselin
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Umpolung Flow Chemistry for the Synthesis of a 3-Oxo-3H-spiro[benzofuran-2,4′-piperidine] Building Block

The Journal of Organic Chemistry
2024-06-07 | Journal article
DOI: 10.1021/acs.joc.4c00337
Contributors: Matthew M. Pompeo; Sean M. Kelly; Frédéric St-Jean; Thomas M. Bass; Derek M. Dalton; Daniel Zell; Chong Han; Lauren E. Sirois; Francis Gosselin
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Data Science Guided Multiobjective Optimization of a Stereoconvergent Nickel-Catalyzed Reduction of Enol Tosylates to Access Trisubstituted Alkenes

ACS Catalysis
2024-04-05 | Journal article
DOI: 10.1021/acscatal.4c00650
Contributors: Natalie P. Romer; Daniel S. Min; Jason Y. Wang; Richard C. Walroth; Kyle A. Mack; Lauren E. Sirois; Francis Gosselin; Daniel Zell; Abigail G. Doyle; Matthew S. Sigman
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Stereoconvergent and -divergent Synthesis of Tetrasubstituted Alkenes by Nickel-Catalyzed Cross-Couplings

Journal of the American Chemical Society
2021-11-17 | Journal article
DOI: 10.1021/jacs.1c08399
Contributors: Daniel Zell; Cian Kingston; Janis Jermaks; Sleight R. Smith; Natalie Seeger; Jana Wassmer; Lauren E. Sirois; Chong Han; Haiming Zhang; Matthew S. Sigman et al.
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An Efficient Second-Generation Manufacturing Process for the pan-RAF Inhibitor Belvarafenib

Organic Process Research & Development
2021-10-15 | Journal article
DOI: 10.1021/acs.oprd.1c00277
Contributors: Daniel Zell; Michael E. Dalziel; Diane E. Carrera; Andreas Stumpf; Stephan Bachmann; Eduardo Mercado-Marin; Stefan G. Koenig; Haiming Zhang; Francis Gosselin
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Total Synthesis of Kadcoccinic Acid A Trimethyl Ester

Journal of the American Chemical Society
2021-08-11 | Journal article
DOI: 10.1021/jacs.1c05521
Contributors: Barry M. Trost; Guoting Zhang; Hadi Gholami; Daniel Zell
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Enantio‐ and Diastereoselective Synthesis of Chiral Allenes by Palladium‐Catalyzed Asymmetric [3+2] Cycloaddition Reactions

Angewandte Chemie
2018-09-24 | Journal article
DOI: 10.1002/ange.201808345
Contributors: Barry M. Trost; Daniel Zell; Christoph Hohn; Guillaume Mata; Autumn Maruniak
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Enantio‐ and Diastereoselective Synthesis of Chiral Allenes by Palladium‐Catalyzed Asymmetric [3+2] Cycloaddition Reactions

Angewandte Chemie International Edition
2018-09-24 | Journal article
DOI: 10.1002/anie.201808345
Contributors: Barry M. Trost; Daniel Zell; Christoph Hohn; Guillaume Mata; Autumn Maruniak
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Mild Cobalt(III)‐Catalyzed Allylative C−F/C−H Functionalizations at Room Temperature

Chemistry – A European Journal
2017-09-07 | Journal article
DOI: 10.1002/chem.201702528
Contributors: Daniel Zell; Valentin Müller; Uttam Dhawa; Markus Bursch; Rubén Rubio Presa; Stefan Grimme; Lutz Ackermann
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Full Selectivity Control in Cobalt(III)‐Catalyzed C−H Alkylations by Switching of the C−H Activation Mechanism

Angewandte Chemie International Edition
2017-08-21 | Journal article
DOI: 10.1002/anie.201704196
Contributors: Daniel Zell; Markus Bursch; Valentin Müller; Stefan Grimme; Lutz Ackermann
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Full Selectivity Control in Cobalt(III)‐Catalyzed C−H Alkylations by Switching of the C−H Activation Mechanism

Angewandte Chemie
2017-08-21 | Journal article
DOI: 10.1002/ange.201704196
Contributors: Daniel Zell; Markus Bursch; Valentin Müller; Stefan Grimme; Lutz Ackermann
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Peer review (2 reviews for 1 publication/grant)

Review activity for Organic process research & development. (2)
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