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Inserm U1220: Toulouse, FR

Employment
Source: Self-asserted source
Léon Kautz

Works (31)

Comparative analysis of dietary iron deprivation and supplementation in a murine model of colitis

FASEB BioAdvances
2025-03-17 | Journal article
DOI: 10.1096/fba.2025-00022
Contributors: Thanina Medjbeur; Ugo Sardo; Prunelle Perrier; Kevin Cormier; Maryline Roy; Anne Dumay; Léon Kautz
Source: check_circle
Crossref

Testing the contribution of fibrinogen like 1 to the pathogenesis of metabolic dysfunction associated steatotic liver disease and hepatocellular carcinoma

2024-12-23 | Preprint
DOI: 10.1101/2024.12.23.628701
Contributors: Jean Personnaz; Lisa Cannizzo; Céline Marie Pauline Martin; Aurore Desquesnes; Manon Sotin; Joanna DaSilva; Hervé Guillou; Léon Kautz
Source: check_circle
Crossref

Comparative analysis of dietary iron deprivation and supplementation in a murine model of colitis

2024-12-22 | Preprint
DOI: 10.1101/2024.12.19.629342
Contributors: Thanina Medjbeur; Ugo Sardo; Prunelle Perrier; Kevin Cormier; Marilyne Roy; Anne Dumay; Léon Kautz
Source: check_circle
Crossref

Fibrinogen‐like 1: A hepatokine linking liver physiology to hematology

HemaSphere
2024-07 | Journal article
DOI: 10.1002/hem3.115
Contributors: Jean Personnaz; Hervé Guillou; Léon Kautz
Source: check_circle
Crossref

The hepatokine FGL1 regulates hepcidin and iron metabolism during the recovery from hemorrhage-induced anemia in mice

2023-04-06 | Preprint | Author
DOI: 10.1101/2023.04.06.535920
Contributors: Ugo Sardo; Prunelle Perrier; Kevin Cormier; Manon Sotin; Aurore Desquesnes; Lisa Cannizzo; Marc Ruiz-Martinez; Julie Thevenin; Benjamin Billoré; Grace Jung et al.
Source: Self-asserted source
Léon Kautz

Differentiating iron-loading anemias using a newly developed and analytically validated ELISA for human serum erythroferrone

PLOS ONE
2021-07-20 | Journal article
DOI: 10.1371/journal.pone.0254851
Part of ISSN: 1932-6203
Contributors: Laura Diepeveen; Rian Roelofs; Nicolai Grebenchtchikov; Rachel van Swelm; Leon Kautz; Dorine Swinkels
Source: Self-asserted source
Léon Kautz

A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the anemia of chronic disease

Blood
2020-08-27 | Journal article
DOI: 10.1182/blood.2019004653
Part of ISSN: 0006-4971
Part of ISSN: 1528-0020
Contributors: Verena Petzer; Piotr Tymoszuk; Malte Asshoff; Joana Carvalho; Jonathan Papworth; Cecilia Deantonio; Luke Bayliss; Matthew Stephen Wake; Markus Seifert; Natascha Brigo et al.
Source: Self-asserted source
Léon Kautz

A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome.

Science translational medicine
2019-07-01 | Journal article
DOI: 10.1126/scitranslmed.aav5467
PMID: 31292266
Source: Self-asserted source
Léon Kautz

Transient decrease of serum iron after acute erythropoietin treatment contributes to hepcidin inhibition by ERFE in mice.

Haematologica
2018-09-28 | Journal article
DOI: 10.3324/haematol.2018.199810
PMID: 30266734
PMC: PMC6395344
Source: Self-asserted source
Léon Kautz

Erythroferrone is not required for the glucoregulatory and hematologic effects of chronic erythropoietin treatment in mice.

Physiological reports
2018-09-01 | Journal article
DOI: 10.14814/phy2.13890
PMID: 30315639
PMC: PMC6185995
Source: Self-asserted source
Léon Kautz

Immunoassay for human serum erythroferrone.

Blood
2017-07-24 | Journal article
DOI: 10.1182/blood-2017-04-777987
PMID: 28739636
PMC: PMC5606005
Source: Self-asserted source
Léon Kautz

Erythroferrone and matriptase‐2 independently regulate hepcidin expression

American Journal of Hematology
2017-05 | Journal article
DOI: 10.1002/ajh.24672
Contributors: Sharraya Aschemeyer; Victoria Gabayan; Tomas Ganz; Elizabeta Nemeth; Léon Kautz
Source: check_circle
Crossref

Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia.

2017-01 | Journal article
DOI: 10.3324/haematol.2016.150227
PMID: 27658439
PMC: PMC5210233
Contributors: Latour C; Wlodarczyk MF; Jung G; Gineste A; Blanchard N; Ganz T; Roth MP; Coppin H; Kautz L
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia.

2015-10 | Journal article
DOI: 10.1182/blood-2015-07-658419
PMID: 26276665
PMC: PMC4616236
Contributors: Kautz L; Jung G; Du X; Gabayan V; Chapman J; Nasoff M; Nemeth E; Ganz T
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

[Erythroferrone, an erythroid regulator of iron metabolism].

2014-10 | Journal article
DOI: 10.1051/medsci/20143010005
PMID: 25311013
Contributors: Kautz L
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Erythroferrone contributes to recovery from anemia of inflammation.

2014-10 | Journal article
DOI: 10.1182/blood-2014-06-584607
PMID: 25193872
PMC: PMC4199959
Contributors: Kautz L; Jung G; Nemeth E; Ganz T
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Identification of erythroferrone as an erythroid regulator of iron metabolism.

2014-07 | Journal article
DOI: 10.1038/ng.2996
PMID: 24880340
PMC: PMC4104984
Contributors: Kautz L; Jung G; Valore EV; Rivella S; Nemeth E; Ganz T
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Molecular liaisons between erythropoiesis and iron metabolism.

2014-07 | Journal article
DOI: 10.1182/blood-2014-05-516252
PMID: 24876565
PMC: PMC4110655
Contributors: Kautz L; Nemeth E
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin.

2014-02 | Journal article
DOI: 10.1002/hep.26648
PMID: 23907767
Contributors: Latour C; Kautz L; Besson-Fournier C; Island ML; Canonne-Hergaux F; Loréal O; Ganz T; Coppin H; Roth MP
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Testing the iron hypothesis in a mouse model of atherosclerosis.

2013-12 | Journal article
DOI: 10.1016/j.celrep.2013.11.009
PMID: 24316081
PMC: PMC3880128
Contributors: Kautz L; Gabayan V; Wang X; Wu J; Onwuzurike J; Jung G; Qiao B; Lusis AJ; Ganz T; Nemeth E
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis.

2012-11 | Journal article
DOI: 10.1182/blood-2012-07-440743
PMID: 22990014
PMC: PMC3488893
Contributors: Ramos E; Ruchala P; Goodnough JB; Kautz L; Preza GC; Nemeth E; Ganz T
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling.

2012-07 | Journal article
DOI: 10.1182/blood-2012-02-411470
PMID: 22611157
Contributors: Besson-Fournier C; Latour C; Kautz L; Bertrand J; Ganz T; Roth MP; Coppin H
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degeneration.

2011-07 | Journal article
DOI: 10.1016/j.ajpath.2011.03.033
PMID: 21703414
PMC: PMC3123855
Contributors: Hadziahmetovic M; Song Y; Wolkow N; Iacovelli J; Kautz L; Roth MP; Dunaief JL
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice.

2011-04 | Journal article
DOI: 10.1002/hep.24178
PMID: 21480335
PMC: PMC3074982
Contributors: Ramos E; Kautz L; Rodriguez R; Hansen M; Gabayan V; Ginzburg Y; Roth MP; Nemeth E; Ganz T
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Iron overload induces BMP6 expression in the liver but not in the duodenum.

2011-02 | Journal article
DOI: 10.3324/haematol.2010.031963
PMID: 20952515
PMC: PMC3031686
Contributors: Kautz L; Besson-Fournier C; Meynard D; Latour C; Roth MP; Coppin H
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6.

2011-01 | Journal article
DOI: 10.1182/blood-2010-07-295147
PMID: 20940420
PMC: PMC3302207
Contributors: Lenoir A; Deschemin JC; Kautz L; Ramsay AJ; Roth MP; Lopez-Otin C; Vaulont S; Nicolas G
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Novel tools for the evaluation of iron metabolism.

2010-12 | Journal article
DOI: 10.3324/haematol.2010.033993
PMID: 21123438
PMC: PMC2995554
Contributors: Kautz L; Nemeth E
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.

2009-09 | Journal article
DOI: 10.1182/blood-2009-02-206771
PMID: 19622835
Contributors: Kautz L; Meynard D; Besson-Fournier C; Darnaud V; Al Saati T; Coppin H; Roth MP
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Lack of the bone morphogenetic protein BMP6 induces massive iron overload.

2009-04 | Journal article
DOI: 10.1038/ng.320
PMID: 19252488
Contributors: Meynard D; Kautz L; Darnaud V; Canonne-Hergaux F; Coppin H; Roth MP
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver.

2008-08 | Journal article
DOI: 10.1182/blood-2008-03-143354
PMID: 18539898
Contributors: Kautz L; Meynard D; Monnier A; Darnaud V; Bouvet R; Wang RH; Deng C; Vaulont S; Mosser J; Coppin H et al.
Source: Self-asserted source
Léon Kautz via Europe PubMed Central

Gene expression profiling of Hfe-/- liver and duodenum in mouse strains with differing susceptibilities to iron loading: identification of transcriptional regulatory targets of Hfe and potential hemochromatosis modifiers.

2007 | Journal article
DOI: 10.1186/gb-2007-8-10-r221
PMID: 17945001
PMC: PMC2246295
Contributors: Coppin H; Darnaud V; Kautz L; Meynard D; Aubry M; Mosser J; Martinez M; Roth MP
Source: Self-asserted source
Léon Kautz via Europe PubMed Central
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