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Employment (6)

Japan Science and Technology Agency: Kawaguchi, Saitama, JP

2021-10-01 to present | Principal Investigator (JST-CREST)
Employment
Source: Self-asserted source
Akiyuki Taruno

Kyoto Prefectural University of Medicine: Kyoto, Kyoto, JP

2018-09-01 to present | Professor (Department of Molecular Cell Physiology)
Employment
Source: Self-asserted source
Akiyuki Taruno

Japan Science and Technology Agency: Kawaguchi, Saitama, JP

2018-10-01 to 2022-03-31 | PRESTO Researcher
Employment
Source: Self-asserted source
Akiyuki Taruno

Kyoto Prefectural University of Medicine: Kyoto, JP

2014-04-01 to 2018-08-31 | Associate Professor (Department of Molecular Cell Physiology)
Employment
Source: Self-asserted source
Akiyuki Taruno

Kyoto Prefectural University of Medicine: Kyoto, JP

2013-04-01 to 2014-03-31 | Assistant professor (Department of Molecular Cell Physiology)
Employment
Source: Self-asserted source
Akiyuki Taruno

University of Pennsylvania: Philadelphia, PA, US

2010-04-01 to 2013-03-31 | Postdoc Researcher (Depatment of Physiology)
Employment
Source: Self-asserted source
Akiyuki Taruno

Works (28)

CALHM1/CALHM3 channel is intrinsically sorted to the basolateral membrane of epithelial cells including taste cells.

Scientific reports
2019-02-25 | Journal article
DOI: 10.1038/s41598-019-39593-5
PMID: 30804437
PMC: PMC6390109
Source: Self-asserted source
Akiyuki Taruno

AAV-Mediated Gene Delivery to Taste Cells of the Tongue.

Methods in molecular biology (Clifton, N.J.)
2019-01-01 | Journal article
DOI: 10.1007/978-1-4939-9139-6_18
PMID: 30783982
Source: Self-asserted source
Akiyuki Taruno

Innate and acquired tolerance to bitter stimuli in mice.

PloS one
2018-12-31 | Journal article
DOI: 10.1371/journal.pone.0210032
PMID: 30596779
PMC: PMC6312290
Source: Self-asserted source
Akiyuki Taruno

Action of Protein Tyrosine Kinase Inhibitors on the Hypotonicity-Stimulated Trafficking Kinetics of Epithelial Na+ Channels (ENaC) in Renal Epithelial Cells: Analysis Using a Mathematical Model.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
2018-10-11 | Journal article
DOI: 10.1159/000494012
PMID: 30308504
Source: Self-asserted source
Akiyuki Taruno

CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes.

Neuron
2018-04-19 | Journal article
DOI: 10.1016/j.neuron.2018.03.043
PMID: 29681531
PMC: PMC5934295
Source: Self-asserted source
Akiyuki Taruno

ATP Release Channels

International Journal of Molecular Sciences
2018-03 | Journal article
DOI: 10.3390/ijms19030808
Source: check_circle
Multidisciplinary Digital Publishing Institute

Quercetin is a Useful Medicinal Compound Showing Various Actions Including Control of Blood Pressure, Neurite Elongation and Epithelial Ion Transport.

Current medicinal chemistry
2018-01-01 | Journal article
DOI: 10.2174/0929867323666160919095043
PMID: 27655075
Source: Self-asserted source
Akiyuki Taruno

The NOX1 isoform of NADPH oxidase is involved in dysfunction of liver sinusoids in nonalcoholic fatty liver disease.

Free radical biology & medicine
2017-12-20 | Journal article
DOI: 10.1016/j.freeradbiomed.2017.12.019
PMID: 29274380
PMC: PMC5969997
Source: Self-asserted source
Akiyuki Taruno

Current-direction/amplitude-dependent single channel gating kinetics of mouse pannexin 1 channel: a new concept for gating kinetics.

Scientific reports
2017-09-05 | Journal article
DOI: 10.1038/s41598-017-10921-x
PMID: 28874774
PMC: PMC5585217
Source: Self-asserted source
Akiyuki Taruno

Post-translational palmitoylation controls the voltage gating and lipid raft association of the CALHM1 channel.

The Journal of physiology
2017-08-14 | Journal article
DOI: 10.1113/jp274164
PMID: 28734079
Source: Self-asserted source
Akiyuki Taruno

Analysis of Aprotinin, a Protease Inhibitor, Action on the Trafficking of Epithelial Na+ Channels (ENaC) in Renal Epithelial Cells Using a Mathematical Model.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
2017-04-04 | Journal article
DOI: 10.1159/000471934
PMID: 28478438
Source: Self-asserted source
Akiyuki Taruno

Actions of Quercetin, a Polyphenol, on Blood Pressure.

Molecules (Basel, Switzerland)
2017-01-29 | Journal article
DOI: 10.3390/molecules22020209
PMID: 28146071
PMC: PMC6155806
Source: Self-asserted source
Akiyuki Taruno

Hypotonicity activates a voltage-dependent membrane conductance in N2a neuroblastoma cells.

Biochemical and biophysical research communications
2017-01-25 | Journal article
DOI: 10.1016/j.bbrc.2017.01.118
PMID: 28130109
Source: Self-asserted source
Akiyuki Taruno

Adeno-Associated Virus-Mediated Gene Transfer into Taste Cells In Vivo.

Chemical senses
2016-10-07 | Journal article
DOI: 10.1093/chemse/bjw101
PMID: 27940927
Source: Self-asserted source
Akiyuki Taruno

Na+ homeostasis by epithelial Na+ channel (ENaC) and Nax channel (Nax): cooperation of ENaC and Nax.

Annals of translational medicine
2016-10-01 | Journal article
DOI: 10.21037/atm.2016.10.42
PMID: 27867979
PMC: PMC5104600
Source: Self-asserted source
Akiyuki Taruno

Simulation of Cl(-) Secretion in Epithelial Tissues: New Methodology Estimating Activity of Electro-Neutral Cl(-) Transporter.

Frontiers in physiology
2015-12-23 | Journal article
DOI: 10.3389/fphys.2015.00370
PMID: 26779025
PMC: PMC4688368
Source: Self-asserted source
Akiyuki Taruno

Calcium homeostasis modulator (CALHM) ion channels.

Pflugers Archiv : European journal of physiology
2015-11-25 | Journal article
DOI: 10.1007/s00424-015-1757-6
PMID: 26603282
PMC: PMC5308871
Source: Self-asserted source
Akiyuki Taruno

How do taste cells lacking synapses mediate neurotransmission? CALHM1, a voltage-gated ATP channel.

BioEssays : news and reviews in molecular, cellular and developmental biology
2013-09-17 | Journal article
DOI: 10.1002/bies.201300077
PMID: 24105910
PMC: PMC3981604
Source: Self-asserted source
Akiyuki Taruno

CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes.

Nature
2013-03-06 | Journal article
DOI: 10.1038/nature11906
PMID: 23467090
PMC: PMC3600154
Source: Self-asserted source
Akiyuki Taruno

Inhibition of presynaptic Na(+)/K(+)-ATPase reduces readily releasable pool size at the avian end-bulb of Held synapse.

Neuroscience research
2011-11-12 | Journal article
DOI: 10.1016/j.neures.2011.11.003
PMID: 22100365
Source: Self-asserted source
Akiyuki Taruno

Regulation of epithelial sodium transport via epithelial Na+ channel.

Journal of biomedicine & biotechnology
2011-10-17 | Journal article
DOI: 10.1155/2011/978196
PMID: 22028593
PMC: PMC3196915
Source: Self-asserted source
Akiyuki Taruno

Analysis of blocker-labeled channels reveals the dependence of recycling rates of ENaC on the total amount of recycled channels.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
2010-01-01 | Journal article
DOI: 10.1159/000324001
PMID: 21220923
Source: Self-asserted source
Akiyuki Taruno

Regulation of paracellular Na+ and Cl(-) conductances by hydrostatic pressure.

Cell biology international
2009-06-12 | Journal article
DOI: 10.1016/j.cellbi.2009.06.007
PMID: 19524694
Source: Self-asserted source
Akiyuki Taruno

Intracellular calcium plays a role as the second messenger of hypotonic stress in gene regulation of SGK1 and ENaC in renal epithelial A6 cells.

American journal of physiology. Renal physiology
2007-10-24 | Journal article
DOI: 10.1152/ajprenal.00250.2007
PMID: 17959754
Source: Self-asserted source
Akiyuki Taruno

Aldosterone-induced modification of osmoregulated ENaC trafficking.

Biochemical and biophysical research communications
2007-07-20 | Journal article
DOI: 10.1016/j.bbrc.2007.07.002
PMID: 17658480
Source: Self-asserted source
Akiyuki Taruno

Involvement of p38 MAPK in hypotonic stress-induced stimulation of beta- and gamma-ENaC expression in renal epithelium.

Biochemical and biophysical research communications
2007-05-07 | Journal article
DOI: 10.1016/j.bbrc.2007.04.192
PMID: 17506993
Source: Self-asserted source
Akiyuki Taruno

Action of neltenexine on anion secretion in human airway epithelia.

Biochemical and biophysical research communications
2007-03-26 | Journal article
DOI: 10.1016/j.bbrc.2007.03.095
PMID: 17400191
Source: Self-asserted source
Akiyuki Taruno

Hypotonicity stimulates renal epithelial sodium transport by activating JNK via receptor tyrosine kinases.

American journal of physiology. Renal physiology
2007-03-06 | Journal article
DOI: 10.1152/ajprenal.00011.2007
PMID: 17344192
Source: Self-asserted source
Akiyuki Taruno

Peer review (2 reviews for 2 publications/grants)

Review activity for Nature (1)
Review activity for PloS one. (1)
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