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ResearcherID: V-7786-2018

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Employment (2)

Nankai University: Tianjin, CN

2021-02 to present | Assistant Professor (Chemistry)
Employment
Source: Self-asserted source
Gongyu Li

University of Wisconsin–Madison: Madison, Wisconsin, US

2017-08-21 to 2021-01-31 | PostDoc (School of Pharmacy)
Employment
Source: Self-asserted source
Gongyu Li

Education and qualifications (4)

University of Michigan: Ann Arbor, MI, US

2019-07 to 2019-08 | Visiting Scholar (Chemistry)
Education
Source: Self-asserted source
Gongyu Li

University of Science and Technology of China: Hefei, Anhui, CN

2012-09-02 to 2017-06-20 | Ph.D. (Department of Chemistry)
Education
Source: Self-asserted source
Gongyu Li

University of Michigan: Ann Arbor, MI, US

2016-04-11 to 2016-08-01 | Visiting Student (Department of Chemistry)
Education
Source: Self-asserted source
Gongyu Li

Jiangxi Normal University: Nanchang, Jiangxi, CN

2008-09-04 to 2012-06-31 | B.S. (Department of Chemistry)
Education
Source: Self-asserted source
Gongyu Li

Professional activities (3)

US HUPO: Portland, OR, US

2020-12-05 to present
Membership
Source: Self-asserted source
Gongyu Li

ACS: washington, DC, US

2019-05-23 to present | Regular Member
Membership
Source: Self-asserted source
Gongyu Li

ASMS: Santa Fe, New Mexico, US

2016-04-11 to present
Membership
Source: Self-asserted source
Gongyu Li

Funding (3)

ASMS Postdoctoral Career Development Award

2019-06 to 2020-06 | Award
American Society for Mass Spectrometry (2019 Galisteo Street, Bldg. I-1 Santa Fe, NM 87505 (USA), US)
Source: Self-asserted source
Gongyu Li

USTC Graduate School Fellowship for International Exchange

2016-04 to 2016-08 | Award
University of Science and Technology of China (Hefei, CN)
GRANT_NUMBER:

GS006
Source: Self-asserted source
Gongyu Li

The Fundamental Research Funds for the Central Universities

2016-03 to 2017-03 | Grant
University of Science and Technology of China (Hefei, CN)
GRANT_NUMBER:

WK6030000026
Source: Self-asserted source
Gongyu Li

Works (44)

High-Coverage Stereoproteome Mapping Uncovers Pervasive Protein Stereoisomerization Associated with Neurodegeneration

Analytical Chemistry
2025-03-13 | Journal article
DOI: 10.1021/acs.analchem.4c06292
Contributors: Xia Xu; Weida Qin; Haohao Fu; Ruomeng Li; Chunxiao Chen; Baofa Sun; Daiwen Pang; Xueguang Shao; Gongyu Li
Source: check_circle
Crossref

Sialylation Shields Glycoproteins from Oxidative Stress: Mechanistic Insights into Sialic Acid Oxidation and Structural Stability

Journal of the American Chemical Society
2025-02-19 | Journal article
DOI: 10.1021/jacs.4c14454
Contributors: Yamei Wang; Dongbei Jin; Lifang Ren; Ning Wang; Yifei Jia; Zhen Zheng; Wensheng Cai; Haohao Fu; Gongyu Li
Source: check_circle
Crossref

Lysine l-lactylation is the dominant lactylation isomer induced by glycolysis

Nature Chemical Biology
2025-01 | Journal article
DOI: 10.1038/s41589-024-01680-8
Contributors: Di Zhang; Jinjun Gao; Zhijun Zhu; Qianying Mao; Zhiqiang Xu; Pankaj K. Singh; Cornelius C. Rimayi; Carlos Moreno-Yruela; Shuling Xu; Gongyu Li et al.
Source: check_circle
Crossref

Sialylation-induced stabilization of dynamic glycoprotein conformations unveiled by time-aligned parallel unfolding and glycan release mass spectrometry

Chemical Science
2024 | Journal article
DOI: 10.1039/D4SC03672G
Contributors: Yifei Jia; Yichang Liu; Yamei Wang; Jinyu Li; Gongyu Li
Source: check_circle
Crossref

Peptide-IR820 Conjugate: A Promising Strategy for Efficient Vascular Disruption and Hypoxia Induction in Melanoma

ACS Applied Materials & Interfaces
2024-08-07 | Journal article
DOI: 10.1021/acsami.4c07503
Contributors: Hongxia Zhang; Mengmeng Jiang; Weiyu Xing; Rui Zhao; Gongyu Li; Zhen Zheng
Source: check_circle
Crossref

Site-selective arene C–H amination with iron-aminyl radical

Nature Catalysis
2024-04-01 | Journal article
DOI: 10.1038/s41929-024-01140-5
Contributors: Chao-Rui Ma; Guan-Wang Huang; Hui Xu; Zhan-Lin Wang; Zheng-Hao Li; Jun Liu; Yin Yang; Gongyu Li; Yanfeng Dang; Fei Wang
Source: check_circle
Crossref

Enhanced chemotherapy and anti-metastasis with in situ nanosphere-to-nanofiber transition

Nano Today
2024-02 | Journal article
DOI: 10.1016/j.nantod.2023.102122
Contributors: Hongxia Zhang; Liyuan Peng; Weida Qin; Deying Jia; Rui Zhao; Mengmeng Jiang; Ming Ji; Lulu Wang; Gongyu Li; Zhen Zheng
Source: check_circle
Crossref

Plasma-Droplet Fusion-Mass Spectrometry Reveals Sub-Millisecond Protein Unfolding Dynamics Induced by Reactive Oxygen Species

Analytical Chemistry
2024-02-13 | Journal article
DOI: 10.1021/acs.analchem.3c03419
Contributors: Jun Liu; Zhen Zheng; Ning Wang; Gongyu Li
Source: check_circle
Crossref

Site-specific chirality-conferred structural compaction differentially mediates the cytotoxicity of Aβ42

Chemical Science
2023 | Journal article
DOI: 10.1039/D3SC00678F
Contributors: Gongyu Li; Chae Kyung Jeon; Min Ma; Yifei Jia; Zhen Zheng; Daniel G. Delafield; Gaoyuan Lu; Elena V. Romanova; Jonathan V. Sweedler; Brandon T. Ruotolo et al.
Source: check_circle
Crossref

Measuring protein unfolding thermodynamic stability in one minute with digital temperature control-equipped nanoESI-mass spectrometry

International Journal of Mass Spectrometry
2023-12 | Journal article
DOI: 10.1016/j.ijms.2023.117151
Contributors: Jun Liu; Yamei Wang; Xiaoli Wang; Weida Qin; Gongyu Li
Source: check_circle
Crossref

Artificial Peptide‐Protein Necrosomes Promote Cell Death

Angewandte Chemie
2023-12-04 | Journal article
DOI: 10.1002/ange.202314578
Part of ISSN: 0044-8249
Part of ISSN: 1521-3757
Contributors: Ruo‐Chen Guo; Ning Wang; Weishu Wang; Zeyu Zhang; Wendi Luo; Yushi Wang; Haiqin Du; Yifei Xu; Gongyu Li; Zhilin Yu
Source: Self-asserted source
Gongyu Li

Enhanced Stability Differentiation of Therapeutic Polyclonal Antibodies with All Ion Unfolding-Ion Mobility-Mass Spectrometry

Journal of the American Society for Mass Spectrometry
2023-10-04 | Journal article
DOI: 10.1021/jasms.3c00215
Contributors: Rui Zhao; Ning Liu; Zhen Zheng; Gongyu Li
Source: check_circle
Crossref

Expedited Evaluation of Conformational Stability–Heterogeneity Associations for Crude Polyclonal Antibodies in Response to Conjugate Vaccines

Analytical Chemistry
2023-07-25 | Journal article
DOI: 10.1021/acs.analchem.3c00223
Contributors: Zhen Zheng; Min Ma; Yifei Jia; Yusi Cui; Rui Zhao; Shuangshuang Li; Cody Wenthur; Lingjun Li; Gongyu Li
Source: check_circle
Crossref

Composite Multidimensional Ion Mobility-Mass Spectrometry for Improved Differentiation of Stereochemical Modifications

Analytical Chemistry
2023-01-31 | Journal article
DOI: 10.1021/acs.analchem.2c03522
Contributors: Xia Xu; Li Han; Zhen Zheng; Rui Zhao; Lingjun Li; Xueguang Shao; Gongyu Li
Source: check_circle
Crossref

Nanosecond Photochemical Reaction (nsPCR) for Enhanced Mass Spectrometric Identification, Quantification, and Visualization of Metabolites and

Methods in Molecular Biology
2022 | Book chapter
DOI: 10.1007/978-1-0716-2030-4_10
Part of ISBN: 9781071620298
Part of ISBN: 9781071620304
Part of ISSN: 1064-3745
Part of ISSN: 1940-6029
Source: Self-asserted source
Gongyu Li

Comparing Selected-Ion Collision Induced Unfolding with All Ion Unfolding Methods for Comprehensive Protein Conformational Characterization

Journal of the American Society for Mass Spectrometry
2022-06-01 | Journal article
DOI: 10.1021/jasms.2c00004
Contributors: Ashley Phetsanthad; Gongyu Li; Chae Kyung Jeon; Brandon T. Ruotolo; Lingjun Li
Source: check_circle
Crossref

Nanosecond Photochemical Reaction for Enhanced Identification, Quantification, and Visualization of Primary Amine-Containing Metabolites by MALDI-Mass Spectrometry

Analytical Chemistry
2022-03-08 | Journal article
DOI: 10.1021/acs.analchem.1c03840
Contributors: Yuan Liu; Gongyu Li; Ting-jia Gu; Lingjun Li
Source: check_circle
Crossref

Native Ion Mobility–Mass Spectrometry-Enabled Fast Structural Interrogation of Labile Protein Surface Modifications at the Intact Protein Level

Analytical Chemistry
2022-02-01 | Journal article
DOI: 10.1021/acs.analchem.1c04503
Contributors: Gongyu Li; Ashley Phetsanthad; Min Ma; Qinying Yu; Ashita Nair; Zhen Zheng; Fengfei Ma; Kellen DeLaney; Seungpyo Hong; Lingjun Li
Source: check_circle
Crossref

Bicarbonate buffers can promote crosslinking and alternative gas-phase dissociation pathways for multiprotein complexes

International Journal of Mass Spectrometry
2021-11 | Journal article
DOI: 10.1016/j.ijms.2021.116687
Contributors: Gongyu Li; Junfeng Huang; Zhen Zheng; Qinjingwen Cao; Yuwei Tian; Guangming Huang; Lingjun Li; Brandon T. Ruotolo
Source: check_circle
Crossref

Targeted Top-Down Mass Spectrometry for the Characterization and Tissue-Specific Functional Discovery of Crustacean Hyperglycemic Hormones (CHH) and CHH Precursor-Related Peptides in Response to Low pH Stress

Journal of the American Society for Mass Spectrometry
2021-06-02 | Journal article
DOI: 10.1021/jasms.0c00474
Contributors: Yang Liu; Gongyu Li; Lingjun Li
Source: check_circle
Crossref

On-Tissue Derivatization with Girard’s Reagent P Enhances N-Glycan Signals for Formalin-Fixed Paraffin-Embedded Tissue Sections in MALDI Mass Spectrometry Imaging

Analytical Chemistry
2020-10-06 | Journal article
DOI: 10.1021/acs.analchem.0c02704
Contributors: Hua Zhang; Xudong Shi; Nhu Q. Vu; Gongyu Li; Zihui Li; Yatao Shi; Miyang Li; Bin Wang; Nathan V. Welham; Manish S. Patankar et al.
Source: check_circle
Crossref

Improved structural elucidation of peptide isomers and their receptors using advanced ion mobility-mass spectrometry

TrAC Trends in Analytical Chemistry
2020-03 | Journal article
DOI: 10.1016/j.trac.2019.05.048
Part of ISSN: 0165-9936
Source: Self-asserted source
Gongyu Li

Subresidue-Resolution Footprinting of Ligand–Protein Interactions by Carbene Chemistry and Ion Mobility–Mass Spectrometry

Analytical Chemistry
2020-01-07 | Journal article
DOI: 10.1021/acs.analchem.9b03827
Contributors: Gaoyuan Lu; Xiaowei Xu; Gongyu Li; Huiyong Sun; Nian Wang; Yinxue Zhu; Ning Wan; Yatao Shi; Guangji Wang; Lingjun Li et al.
Source: check_circle
Crossref

Molecular basis for chirality-regulated Aβ self-assembly and receptor recognition revealed by ion mobility-mass spectrometry

Nature Communications
2019-11-06 | Journal article
DOI: 10.1038/s41467-019-12346-8
Contributors: Gongyu Li; Kellen DeLaney; Lingjun Li
Source: check_circle
Crossref

Nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling

Nature Communications
2019-10-16 | Journal article
DOI: 10.1038/s41467-019-12548-0
Contributors: Gongyu Li; Fengfei Ma; Qinjingwen Cao; Zhen Zheng; Kellen DeLaney; Rui Liu; Lingjun Li
Source: check_circle
Crossref

Charge‐dependent modulation of specific and nonspecific protein‐metal ion interactions in nanoelectrospray ionization mass spectrometry

Rapid Communications in Mass Spectrometry
2019-10-15 | Journal article
DOI: 10.1002/rcm.8493
Contributors: Shihui Zheng; Siming Yuan; Zhuanghao Hou; Gongyu Li; Yuting Chen; Yang Pan; Yangzhong Liu; Guangming Huang
Source: check_circle
Crossref

Ultrafast Microelectrophoresis: Behind Direct Mass Spectrometry Measurements of Proteins and Metabolites in Living Cell/Cells

Analytical Chemistry
2019-08-20 | Journal article
DOI: 10.1021/acs.analchem.9b00716
Contributors: Yuting Chen; Gongyu Li; Siming Yuan; Yang Pan; Yangzhong Liu; Guangming Huang
Source: check_circle
Crossref

Visualization and Identification of Neurotransmitters in Crustacean Brain via Multifaceted Mass Spectrometric Approaches

ACS Chemical Neuroscience
2019-03-20 | Journal article
DOI: 10.1021/acschemneuro.8b00730
Contributors: Qinjingwen Cao; Yijia Wang; Bingming Chen; Fengfei Ma; Ling Hao; Gongyu Li; Chuanzi Ouyang; Lingjun Li
Source: check_circle
Crossref

Characterizing and alleviating ion suppression effects in atmospheric pressure matrix‐assisted laser desorption/ionization

Rapid Communications in Mass Spectrometry
2019-02-28 | Journal article
DOI: 10.1002/rcm.8358
Contributors: Gongyu Li; Qinjingwen Cao; Yang Liu; Kellen DeLaney; Zichuan Tian; Eugene Moskovets; Lingjun Li
Source: check_circle
Crossref

Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein

Nature Communications
2019-01 | Journal article
DOI: 10.1038/s41467-018-08102-z
Part of ISSN: 2041-1723
Source: Self-asserted source
Gongyu Li

Reliable Tracking In-solution Protein Unfolding via Ultrafast Thermal Unfolding/Ion Mobility-Mass Spectrometry

Analytical Chemistry
2018-06 | Journal article
DOI: 10.1021/acs.analchem.8b00859
Part of ISSN: 0003-2700
Contributors: Gongyu Li; Shihui Zheng; Yuting Chen; Zhuanghao Hou; Guangming Huang
Source: Self-asserted source
Gongyu Li via Crossref Metadata Search

In Situ Living Cell Protein Analysis by Single-Step Mass Spectrometry.

Analytical chemistry
2018-03 | Journal article
DOI: 10.1021/acs.analchem.7b05055
PMID: 29406694
Contributors: Li G; Yuan S; Zheng S; Liu Y; Huang G
Source: Self-asserted source
Gongyu Li via Europe PubMed Central

The Effect of Salts in Promoting Specific and Competitive Interactions between Zinc Finger Proteins and Metals

Journal of The American Society for Mass Spectrometry
2017-09-08 | Journal article
DOI: 10.1007/s13361-017-1789-6
Contributors: Gongyu Li; Siming Yuan; Shihui Zheng; Yuting Chen; Zhen Zheng; Yangzhong Liu; Guangming Huang
Source: Self-asserted source
Gongyu Li via Crossref Metadata Search

Intracellular synthesis of d-aminoluciferin for bioluminescence generation.

Chemical communications (Cambridge, England)
2017-03 | Journal article
DOI: 10.1039/c7cc00999b
PMID: 28288221
Source: Self-asserted source
Gongyu Li via Europe PubMed Central

Mechanistic study of CBT-Cys click reaction and its application for identifying bioactive N-terminal cysteine peptides in amniotic fluid.

Chemical science
2017-01 | Journal article
DOI: 10.1039/c6sc01461e
PMID: 28451168
PMC: PMC5308401
Source: Self-asserted source
Gongyu Li via Europe PubMed Central

Binding States of Protein–Metal Complexes in Cells

Analytical Chemistry
2016-11 | Journal article
DOI: 10.1021/acs.analchem.6b00032
Contributors: Gongyu Li; Siming Yuan; Yang Pan; Yangzhong Liu; Guangming Huang
Source: Self-asserted source
Gongyu Li via Crossref Metadata Search

Hydrazide d-luciferin for in vitro selective detection and intratumoral imaging of Cu(2.).

Biosensors & bioelectronics
2016-09 | Journal article
DOI: 10.1016/j.bios.2016.04.067
PMID: 27131992
Source: Self-asserted source
Gongyu Li via Europe PubMed Central

Sheathless interface to match flow rate of capillary electrophoresis with electrospray mass spectrometry using regular-sized capillary

Rapid Communications in Mass Spectrometry
2016-08 | Journal article
DOI: 10.1002/rcm.7621
Contributors: Yue Yin; Gongyu Li; Yafeng Guan; Guangming Huang
Source: Self-asserted source
Gongyu Li via Crossref Metadata Search

Using “On/Off”19F NMR/Magnetic Resonance Imaging Signals to Sense Tyrosine Kinase/Phosphatase Activity in Vitro and in Cell Lysates

Analytical Chemistry
2016-03 | Journal article
DOI: 10.1021/acs.analchem.6b00036
Contributors: Zhen Zheng; Hongbin Sun; Chen Hu; Gongyu Li; Xiaomei Liu; Peiyao Chen; Yusi Cui; Jing Liu; Junfeng Wang; Gaolin Liang
Source: Self-asserted source
Gongyu Li via Crossref Metadata Search

Direct sequencing of a disulfide-linked peptide with electrospray ionization tandem mass spectrometry

The Analyst
2015 | Journal article
DOI: 10.1039/c5an00011d
Contributors: Gongyu Li; Jiying Pei; Yue Yin; Guangming Huang
Source: Self-asserted source
Gongyu Li via Crossref Metadata Search

Increased disulfide peptide sequence coverage via “cleavage ON/OFF” switch during nanoelectrospray

RSC Adv.
2014 | Journal article
DOI: 10.1039/c4ra12386g
Contributors: Gongyu Li; Yue Yin; Guangming Huang
Source: Self-asserted source
Gongyu Li via Crossref Metadata Search

Alleviation of ion suppression effect in sonic spray ionization with induced alternating current voltage

J. Mass Spectrom.
2014-06 | Journal article
DOI: 10.1002/jms.3385
Contributors: Gongyu Li; Guangming Huang
Source: Self-asserted source
Gongyu Li via Crossref Metadata Search

Screening of Complicated Matrixes with Paper Assisted Ultrasonic Spray Ionization Mass Spectrometry

J. Am. Soc. Mass Spectrom.
2014-03 | Journal article
DOI: 10.1007/s13361-014-0862-7
Contributors: Hongying Zhu; Gongyu Li; Guangming Huang
Source: Self-asserted source
Gongyu Li via Crossref Metadata Search

Electrochemical behavior of cuprous oxide-reduced graphene oxide nanocomposites and their application in nonenzymatic hydrogen peroxide sensing

Electrochim. Acta
2012-10-26 | Journal article
DOI: 10.1016/j.electacta.2012.10.070
EID:

2-s2.0-84870226152
Source: Self-asserted source
Gongyu Li
grade
Preferred source (of 2)‎

Peer review (17 reviews for 6 publications/grants)

Review activity for ACS omega. (5)
Review activity for Analytical chemistry. (3)
Review activity for Chemical engineering journal. (1)
Review activity for Chinese Chemical Letters. (4)
Review activity for Journal of the American Society for Mass Spectrometry. (1)
Review activity for Journal of the American Society for Mass Spectrometry. (3)
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