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Works (4)

Release of STK24/25 suppression on MEKK3 signaling in endothelial cells confers cerebral cavernous malformation

JCI Insight
2023-03-08 | Journal article
Contributors: Xi Yang; Shi-Ting Wu; Rui Gao; Rui Wang; Yixuan Wang; Zhenkun Dong; Lu Wang; Chunxiao Qi; Xiaohong Wang; M. Lienhard Schmitz et al.
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CCM2L (Cerebral Cavernous Malformation 2 Like) Deletion Aggravates Cerebral Cavernous Malformation Through Map3k3-KLF Signaling Pathway

Stroke
2021-04 | Journal article
Contributors: Jaesung P. Choi; Xi Yang; Shuang He; Renhua Song; Zi-Ran Xu; Matthew Foley; Justin J.-L. Wong; Cheng-Ran Xu; Xiangjian Zheng
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Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican

Journal of Experimental Medicine
2020-10-05 | Journal article
Contributors: Courtney C. Hong; Alan T. Tang; Matthew R. Detter; Jaesung P. Choi; Rui Wang; Xi Yang; Andrea A. Guerrero; Carl F. Wittig; Nicholas Hobson; Romuald Girard et al.
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Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations

Science Advances
2018-11-02 | Journal article
Contributors: Jaesung P. Choi; Rui Wang; Xi Yang; Xian Wang; Lu Wang; Ka Ka Ting; Matthew Foley; Victoria Cogger; Zhuo Yang; Feng Liu et al.
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