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Base metal catalysis, Radical cross-coupling, Carbohydrate chemistry, Green/sustainable chemical synthesis
Singapore

Biography

Dr. Ming Joo Koh was born and raised in Singapore. He received his B.Sc. degree (First Class Honors) in Chemistry & Biological Chemistry from Nanyang Technological University in 2012, before heading to Boston College for his Ph.D. and post-doctoral studies under the supervision of Professor Amir Hoveyda from 2012-2018. In 2018, Dr. Koh joined the Department of Chemistry at the National University of Singapore as a President's Assistant Professor and was promoted to Associate Professor with tenure in 2023. Currently, Dr. Koh is a Dean’s Chair Professor and Deputy Head of Department for Research. His research focuses on developing sustainable and practical catalytic solutions that address critical challenges in chemical synthesis through base metal catalysis and radical cross-coupling, which were published in top scientific journals such as Nature, Nature Catalysis and Nature Chemistry. Dr. Koh’s internationally recognized program in sustainable chemical synthesis has won him numerous research awards, including the Asian Core Program Lectureship Awards for Japan, Korea, China, Taiwan and Thailand (2019, 2022, 2023), Innovators Under 35 (TR35) Asia Pacific Award (2021), TCI-SNIC Industry Award in Synthetic Chemistry (2021), Thieme Chemistry Journals Award (2022), C&EN’s Talented 12 Award (2022), Young Scientist Award, SNAS (2022), Young Researcher Award, NUS (2023), Novartis Early Career Award in Chemistry (2023) and Mitsui Chemicals Catalysis Science Award for Creative Work (2024).

Activities

Employment (5)

National University of Singapore: Singapore, SG

2023-07 to present | Associate Professor (Chemistry)
Employment
Source: Self-asserted source
Ming Joo Koh

National University of Singapore: Singapore, SG

2024-07 to 2027-07 | Dean's Chair Professor (Chemistry)
Employment
Source: Self-asserted source
Ming Joo Koh

National University of Singapore: Singapore, SG

2024-07 to 2027-07 | Deputy Head of Research (Chemistry)
Employment
Source: Self-asserted source
Ming Joo Koh

National University of Singapore: Singapore, SG

2018-06 to 2023-06 | Assistant Professor (Chemistry)
Employment
Source: Self-asserted source
Ming Joo Koh

Boston College: Chestnut Hill, MA, US

2018-01 to 2018-06 | Post-Doctoral Fellow (Chemistry)
Employment
Source: Self-asserted source
Ming Joo Koh

Education and qualifications (2)

Boston College: Chestnut Hill, MA, US

2012-09 to 2017-12 | Ph.D. in Organic Chemistry (Chemistry)
Education
Source: Self-asserted source
Ming Joo Koh

Nanyang Technological University: Singapore, Singapore, SG

2008-09 to 2012-06 | B.Sc. in Chemistry & Biological Chemistry, First Class Honors (Chemistry & Biological Chemistry)
Education
Source: Self-asserted source
Ming Joo Koh

Works (50 of 89)

Items per page:
Page 1 of 2

A Homolytic Substitution Approach for Directing Group-Free Nickel-Catalyzed Dialkylation of Unactivated Alkenes

Synlett
2025-02 | Journal article
Contributors: Ming Joo Koh; Fei Cong; Jun Wei Ng
Source: check_circle
Crossref

Multicomponent Construction of Tertiary Alkylamines by Photoredox/Nickel-Catalyzed Aminoalkylation of Organohalides

Journal of the American Chemical Society
2024-10-23 | Journal article
Contributors: Tao Yang; Wenhui Xiong; Guangyu Sun; Weiran Yang; Mandi Lu; Ming Joo Koh
Source: check_circle
Crossref

Kinetically controlled Z-alkene synthesis using iron-catalysed allene dialkylation

Nature Synthesis
2024-09-26 | Journal article
Contributors: Tong-De Tan; Kai Ze Tee; Xiaohua Luo; Peng-Cheng Qian; Xinglong Zhang; Ming Joo Koh
Source: check_circle
Crossref

Direct radical functionalization of native sugars

Nature
2024-07-11 | Journal article | Author
Part of ISSN: 0028-0836
Part of ISSN: 1476-4687
Contributors: Yi Jiang; Yi Wei; Qian-Yi Zhou; Guo-Quan Sun; Xia-Ping Fu; Nikita Levin; Yijun Zhang; Wen-Qiang Liu; NingXi Song; Shabaz Mohammed et al.
Source: Self-asserted source
Ming Joo Koh

Electrochemical Synthesis of C(sp3)‐Rich Amines by Aminative Carbofunctionalization of Carbonyl Compounds

Angewandte Chemie International Edition
2024-06-21 | Journal article
Contributors: Wen‐Qiang Liu; Boon Chong Lee; NingXi Song; Zhenghao He; Zi‐An Shen; Yixin Lu; Ming Joo Koh
Source: check_circle
Crossref

Electrochemical Synthesis of C(sp3)‐Rich Amines by Aminative Carbofunctionalization of Carbonyl Compounds

Angewandte Chemie
2024-06-21 | Journal article
Contributors: Wen‐Qiang Liu; Boon Chong Lee; NingXi Song; Zhenghao He; Zi‐An Shen; Yixin Lu; Ming Joo Koh
Source: check_circle
Crossref

Accessing Fluorinated Tertiary Homoallylamines via Photocatalytic Defluorinative Aminoalkylation of Fluoroalkyl-Substituted Alkenes

ACS Catalysis
2024-06-07 | Journal article
Contributors: Wenhui Xiong; Guangyu Sun; Meijuan Zhou; Mandi Lu; Ming Joo Koh; Tao Yang
Source: check_circle
Crossref

A Bimolecular Homolytic Substitution-Enabled Platform for Multicomponent Cross-Coupling of Unactivated Alkenes

Journal of the American Chemical Society
2024-04-17 | Journal article
Contributors: Fei Cong; Guo-Quan Sun; Si-Han Ye; Rui Hu; Weidong Rao; Ming Joo Koh
Source: check_circle
Crossref

Enantioselective synthesis of multifunctional alkylboronates via N-heterocyclic carbene–nickel-catalysed carboboration of alkenes

Nature Synthesis
2024-03-07 | Journal article
Contributors: Xiaohua Luo; Wei Mao; Chen-Fei Liu; Yu-Qi Wang; Jing Nie; Shi-Liang Shi; Jun-An Ma; Ming Joo Koh
Source: check_circle
Crossref

N-glycoside synthesis through combined copper- and photoredox-catalysed N-glycosylation of N-nucleophiles

Nature Synthesis
2024-03-01 | Journal article
Contributors: Qikai Sun; Quanquan Wang; Wenzhuo Qin; Kaiyu Jiang; Gang He; Ming Joo Koh; Gong Chen
Source: check_circle
Crossref

Congested C(sp3)-rich architectures enabled by iron-catalysed conjunctive alkylation

Nature Catalysis
2024-02-23 | Journal article
Contributors: Tong-De Tan; Juan M. I. Serviano; Xiaohua Luo; Peng-Cheng Qian; Patrick L. Holland; Xinglong Zhang; Ming Joo Koh
Source: check_circle
Crossref

Selective 1,2‐Hydroarylation(Alkenylation) of gem‐Difluoroalkenes to Access (−CF2H) Motifs

Angewandte Chemie International Edition
2024-02-12 | Journal article
Contributors: Leroy Qi Hao Lin; Ángel Rentería‐Gómez; Robert T. Martin; Ying‐Qi Zhang; Kelvin Zhi Wei Ong; Adam B. Parris; Osvaldo Gutierrez; Ming Joo Koh
Source: check_circle
Crossref

Selective 1,2‐Hydroarylation(Alkenylation) of gem‐Difluoroalkenes to Access (−CF2H) Motifs

Angewandte Chemie
2024-02-12 | Journal article
Contributors: Leroy Qi Hao Lin; Ángel Rentería‐Gómez; Robert T. Martin; Ying‐Qi Zhang; Kelvin Zhi Wei Ong; Adam B. Parris; Osvaldo Gutierrez; Ming Joo Koh
Source: check_circle
Crossref

1.12 Nickel-Catalyzed Alkene Dicarbofunctionalization

2023 | Book chapter
Contributors: B. C. Lee; L. Lin; C. Ko; M. J. Koh
Source: check_circle
Crossref

N-Heterocyclic carbenes as privileged ligands for nickel-catalysed alkene functionalisation

Chemical Society Reviews
2023 | Journal article
Contributors: Boon Chong Lee; Chen-Fei Liu; Leroy Qi Hao Lin; Kang Zheng Yap; NingXi Song; Charyl Hui Min Ko; Priscilla Hee Chan; Ming Joo Koh
Source: check_circle
Crossref

A Bimolecular Homolytic Substitution-Enabled Platform for Multicomponent Cross-Coupling of Unactivated Alkenes

2023-12-22 | Preprint
Contributors: Fei Cong; Guo-Quan Sun; Si-Han Ye; Rui Hu; Weidong Rao; Ming Joo Koh
Source: check_circle
Crossref

Recent Advances in First-Row Transition Metal-Catalyzed Reductive Coupling Reactions for π-Bond Functionalization and C-Glycosylation

Accounts of Chemical Research
2023-11-21 | Journal article
Contributors: Yi Wei; Leroy Qi Hao Lin; Boon Chong Lee; Ming Joo Koh
Source: check_circle
Crossref

Enantioselective C–C cross-coupling of unactivated alkenes

Nature Catalysis
2023-10-05 | Journal article
Contributors: Zi-Chao Wang; Xiaohua Luo; Jia-Wen Zhang; Chen-Fei Liu; Ming Joo Koh; Shi-Liang Shi
Source: check_circle
Crossref

Diversification of Glycosyl Compounds via Glycosyl Radicals

Angewandte Chemie
2023-09-18 | Journal article
Contributors: Yi Jiang; Yijun Zhang; Boon Chong Lee; Ming Joo Koh
Source: check_circle
Crossref

Diversification of Glycosyl Compounds via Glycosyl Radicals

Angewandte Chemie International Edition
2023-09-18 | Journal article
Contributors: Yi Jiang; Yijun Zhang; Boon Chong Lee; Ming Joo Koh
Source: check_circle
Crossref

Stereoselective C‐Aryl Glycosylation by Catalytic Cross‐Coupling of Heteroaryl Glycosyl Sulfones

Angewandte Chemie International Edition
2023-04-24 | Journal article
Contributors: Quanquan Wang; Boon Chong Lee; NingXi Song; Ming Joo Koh
Source: check_circle
Crossref

Stereoselective C‐Aryl Glycosylation by Catalytic Cross‐Coupling of Heteroaryl Glycosyl Sulfones

Angewandte Chemie
2023-04-24 | Journal article
Contributors: Quanquan Wang; Boon Chong Lee; NingXi Song; Ming Joo Koh
Source: check_circle
Crossref

A Photoinduced, Nickel‐Catalyzed Reaction for the Stereoselective Assembly of C‐Linked Glycosides and Glycopeptides

Angewandte Chemie
2023-01-26 | Journal article
Contributors: Yi Wei; Quanquan Wang; Ming Joo Koh
Source: check_circle
Crossref

A Photoinduced, Nickel‐Catalyzed Reaction for the Stereoselective Assembly of C‐Linked Glycosides and Glycopeptides

Angewandte Chemie International Edition
2023-01-26 | Journal article
Contributors: Yi Wei; Quanquan Wang; Ming Joo Koh
Source: check_circle
Crossref

Diastereo- and enantioselective synthesis of compounds with a trifluoromethyl- and fluoro-substituted carbon centre

Nature Chemistry
2022-12 | Journal article
Contributors: Shibo Xu; Juan del Pozo; Filippo Romiti; Yue Fu; Binh Khanh Mai; Ryan J. Morrison; KyungA Lee; Shaowei Hu; Ming Joo Koh; Jaehee Lee et al.
Source: check_circle
Crossref

Catalytic Multicomponent Synthesis of C‐Acyl Glycosides by Consecutive Cross‐Electrophile Couplings

Angewandte Chemie International Edition
2022-11-14 | Journal article
Contributors: Yi Jiang; Kai Yang; Yi Wei; Quanquan Wang; Shi‐Jun Li; Yu Lan; Ming Joo Koh
Source: check_circle
Crossref

Catalytic Multicomponent Synthesis of C‐Acyl Glycosides by Consecutive Cross‐Electrophile Couplings

Angewandte Chemie
2022-11-14 | Journal article
Contributors: Yi Jiang; Kai Yang; Yi Wei; Quanquan Wang; Shi‐Jun Li; Yu Lan; Ming Joo Koh
Source: check_circle
Crossref

Synthesis of tri- and tetrasubstituted stereocentres by nickel-catalysed enantioselective olefin cross-couplings

Nature Catalysis
2022-10-19 | Journal article
Contributors: Chen-Fei Liu; Zi-Chao Wang; Xiaohua Luo; Jiawei Lu; Charyl Hui Min Ko; Shi-Liang Shi; Ming Joo Koh
Source: check_circle
Crossref

Visible light activation enables desulfonylative cross-coupling of glycosyl sulfones

Nature Synthesis
2022-09-22 | Journal article
Contributors: Quanquan Wang; Boon Chong Lee; Ting Jun Tan; Yi Jiang; Wei Han Ser; Ming Joo Koh
Source: check_circle
Crossref

Directing group-free approaches for three-component catalytic dicarbofunctionalization of unactivated alkenes

Cell Reports Physical Science
2022-06 | Journal article
Contributors: Hongyu Wang; Ming Joo Koh
Source: check_circle
Crossref

Stereoselective Synthesis of Trisubstituted Alkenes by Nickel‐Catalyzed Benzylation and Alkene Isomerization

Angewandte Chemie International Edition
2022-06-27 | Journal article
Contributors: Yunlong Zhao; Chen‐Fei Liu; Leroy Qi Hao Lin; Albert S. C. Chan; Ming Joo Koh
Source: check_circle
Crossref

Stereoselective Synthesis of Trisubstituted Alkenes by Nickel‐Catalyzed Benzylation and Alkene Isomerization

Angewandte Chemie
2022-06-27 | Journal article
Contributors: Yunlong Zhao; Chen‐Fei Liu; Leroy Qi Hao Lin; Albert S. C. Chan; Ming Joo Koh
Source: check_circle
Crossref

Base-Mediated Site-Selective Hydroamination of Alkenes

Synthesis
2022-03 | Journal article
Contributors: Ping Li; Boon Chong Lee; Ming Joo Koh; Xiaoxiang Zhang
Source: check_circle
Crossref

Secondary phosphine oxide-activated nickel catalysts for site-selective alkene isomerization and remote hydrophosphination

Chem Catalysis
2022-03 | Journal article
Contributors: Lin Huang; En Qi Lim; Ming Joo Koh
Source: check_circle
Crossref

Author Correction: Directing-group-free catalytic dicarbofunctionalization of unactivated alkenes

Nature Chemistry
2022-02 | Journal article
Contributors: Hongyu Wang; Chen-Fei Liu; Robert T. Martin; Osvaldo Gutierrez; Ming Joo Koh
Source: check_circle
Crossref

Directing-group-free catalytic dicarbofunctionalization of unactivated alkenes

Nature Chemistry
2022-02 | Journal article
Contributors: Hongyu Wang; Chen-Fei Liu; Robert T. Martin; Osvaldo Gutierrez; Ming Joo Koh
Source: check_circle
Crossref

Iron-catalysed reductive cross-coupling of glycosyl radicals for the stereoselective synthesis of C-glycosides

Nature Synthesis
2022-02-17 | Journal article
Contributors: Quanquan Wang; Qikai Sun; Yi Jiang; Huixing Zhang; Lu Yu; Changlin Tian; Gong Chen; Ming Joo Koh
Source: check_circle
Crossref

N-Heterocyclic Carbene–Nickel-Catalyzed Regioselective Diarylation of Aliphatic-1,3-Dienes

ACS Catalysis
2022-01-07 | Journal article
Contributors: Hongyu Wang; Chen-Fei Liu; Tong-De Tan; Kyna Ru Bin Khoo; Ming Joo Koh
Source: check_circle
Crossref

Secondary Phosphine Oxide-Activated Nickel Catalysts for Site-Selective Alkene Isomerization and Remote Hydrophosphination

2021-09-08 | Preprint
Contributors: Lin Huang; En Qi Lim; Ming Joo Koh
Source: check_circle
Crossref

Secondary Phosphine Oxide-Activated Nickel Catalysts for Site-Selective Alkene Isomerization and Remote Hydrophosphination

2021-09-08 | Other
Contributors: Lin Huang; En Qi Lim; Ming Joo Koh
Source: check_circle
Crossref

Olefin functionalization/isomerization enables stereoselective alkene synthesis

Nature Catalysis
2021-07-29 | Journal article
Contributors: Chen-Fei Liu; Hongyu Wang; Robert T. Martin; Haonan Zhao; Osvaldo Gutierrez; Ming Joo Koh
Source: check_circle
Crossref

Catalytic Regioselective Olefin Hydroarylation(alkenylation) by Sequential Carbonickelation-Hydride Transfer

Journal of the American Chemical Society
2021-06-30 | Journal article
Contributors: Chen-Fei Liu; Xiaohua Luo; Hongyu Wang; Ming Joo Koh
Source: check_circle
Crossref

Photoinduced Nickel-Catalyzed Deaminative Cross-Electrophile Coupling for C(sp2)–C(sp3) and C(sp3)–C(sp3) Bond Formation

ACS Catalysis
2021-06-04 | Journal article
Contributors: Tao Yang; Yi Wei; Ming Joo Koh
Source: check_circle
Crossref

Photoinduced Nickel-Catalyzed Deaminative Cross-Electrophile Coupling

2021-03-10 | Other
Contributors: Tao Yang; Yi Wei; Ming Joo Koh
Source: check_circle
Crossref

Iron‐Catalyzed Regioselective Alkenylboration of Olefins

Angewandte Chemie International Edition
2021-01-25 | Journal article
Contributors: Xiaolong Yu; Hongling Zheng; Haonan Zhao; Boon Chong Lee; Ming Joo Koh
Source: check_circle
Crossref

Iron‐Catalyzed Regioselective Alkenylboration of Olefins

Angewandte Chemie
2021-01-25 | Journal article
Contributors: Xiaolong Yu; Hongling Zheng; Haonan Zhao; Boon Chong Lee; Ming Joo Koh
Source: check_circle
Crossref

Ultrahigh-yield on-surface synthesis and assembly of circumcoronene into a chiral electronic Kagome-honeycomb lattice

Science Advances
2021-01-15 | Journal article
Contributors: Mykola Telychko; Guangwu Li; Pingo Mutombo; Diego Soler-Polo; Xinnan Peng; Jie Su; Shaotang Song; Ming Joo Koh; Mark Edmonds; Pavel Jelínek et al.
Source: check_circle
Crossref

Real-Space Imaging of a Single-Molecule Monoradical Reaction

Journal of the American Chemical Society
2020 | Journal article
EID:

2-s2.0-85089607841

Part of ISBN:

15205126 00027863

Contributors: Song, S.; Guo, N.; Li, X.; Li, G.; Haketa, Y.; Telychko, M.; Su, J.; Lyu, P.; Qiu, Z.; Fang, H. et al.
Source: Self-asserted source
Ming Joo Koh via Scopus - Elsevier

Site-Selective Remote Protoboration by Fe Catalysis

Trends in Chemistry
2020-12 | Journal article
Contributors: Xiaolong Yu; Haonan Zhao; Ming Joo Koh
Source: check_circle
Crossref

Chemoselective Union of Olefins, Organohalides, and Redox-Active Esters Enables Regioselective Alkene Dialkylation

Journal of the American Chemical Society
2020-12-23 | Journal article
Contributors: Tao Yang; Yi Jiang; Yixin Luo; Joel Jun Han Lim; Yu Lan; Ming Joo Koh
Source: check_circle
Crossref
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Peer review (65 reviews for 14 publications/grants)

Review activity for Accounts of chemical research. (5)
Review activity for ACS catalysis. (16)
Review activity for Carbohydrate research (2)
Review activity for Chem. (2)
Review activity for ChemBioChem. (1)
Review activity for ChemCatChem (1)
Review activity for Journal of catalysis. (1)
Review activity for Journal of organic chemistry. (9)
Review activity for Nature Catalysis. (1)
Review activity for Nature chemistry. (2)
Review activity for Nature communications (4)
Review activity for Nature synthesis. (1)
Review activity for Organic letters. (18)
Review activity for Organometallics. (2)