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Activities

Employment (3)

University of Houston: Houston, Texas, US

2024-07-01 to present | Assistant Professor (Pharmacological and Pharmaceutical Sciences)
Employment
Source: Self-asserted source
Guizhen Zhao

University of Michigan–Ann Arbor: Ann Arbor, US

2023-02-01 to 2024-06-30 | Research Investigator (Internal Medicine, Cardiovascular Medicine)
Employment
Source: Self-asserted source
Guizhen Zhao

University of Michigan–Ann Arbor: Ann Arbor, US

2018-04-01 to 2023-01-31 | Postdoc (Department of Internal Medince, Cardiovascular Medince)
Employment
Source: Self-asserted source
Guizhen Zhao

Education and qualifications (2)

Peking University Health Science Centre: Beijing, Beijing, CN

2014-09-01 to 2018-01-05 | PhD (Department of Physiology and Pathophysiology)
Education
Source: Self-asserted source
Guizhen Zhao

Peking University: Beijing, CN

2009-09-01 to 2014-07-31 | Bachelor Degree (School of Basic Medical Sciences)
Education
Source: Self-asserted source
Guizhen Zhao

Funding (3)

Metaboloepigenetics and Atherosclerosis

2024-04-01 to 2029-02-28 | Grant
National Heart Lung and Blood Institute (Bethesda, US)
GRANT_NUMBER: R01HL172832
Source: Self-asserted source
Guizhen Zhao via DimensionsWizard

The Role of BAF60c in Atherosclerosis

2023-01-01 to 2025-12-31 | Grant
American Heart Association (Dallas, US)
GRANT_NUMBER:

936135

Source: Self-asserted source
Guizhen Zhao via DimensionsWizard
grade
Preferred source (of 2)‎

The role of Krüppel Like Factor 11 in abdominal aortic aneurysm

2020-01-01 to 2021-12-31 | Grant
American Heart Association (Dallas, US)
GRANT_NUMBER:

20POST35110064

Source: Self-asserted source
Guizhen Zhao via DimensionsWizard
grade
Preferred source (of 2)‎

Works (25)

Adenosine kinase inhibition protects mice from abdominal aortic aneurysm via epigenetic modulation of VSMC inflammation.

Cardiovascular research
2024-05-09 | Journal article
Contributors: Xu J; Liu Z; Yang Q; QIAN MA; Yaqi Zhou; Cai Y; Zhao D; Zhao G; Lu T; kunfu ouyang et al.
Source: Self-asserted source
Guizhen Zhao

SWI/SNF Complex in Vascular Smooth Muscle Cells and Its Implications in Cardiovascular Pathologies.

Cells
2024-01-16 | Journal article
Contributors: Liu H; Yang Zhao; Zhao G; Deng Y; Chen YE; Jifeng Zhang
Source: Self-asserted source
Guizhen Zhao

Single-Molecule Spatial Transcriptomics of Human Thoracic Aortic Aneurysms Uncovers Calcification-Related <i>CARTPT</i>-Expressing Smooth Muscle Cells.

Arteriosclerosis, thrombosis, and vascular biology
2023-10-12 | Journal article | Author
Contributors: Dogukan Mizrak; Yang Zhao; Feng H; Macaulay J; Tang Y; Zain Sultan; Guizhen Zhao; Yanhong Guo; Jifeng Zhang; Bo Yang et al.
Source: Self-asserted source
Guizhen Zhao

Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis.

Cell reports
2023-09-27 | Journal article
Contributors: Zhao Y; Liu Y; Zhao G; Lu H; Liu Y; Xue C; Chang Z; Liu H; Deng Y; Liang W et al.
Source: Self-asserted source
Guizhen Zhao

Generating endogenous Myh11-driven Cre mice for sex-independent gene deletion in smooth muscle cells.

JCI insight
2023-07-24 | Journal article
Contributors: Zhao Y; Zhao G; Chang Z; Zhu T; Zhao Y; Haocheng Lu; Chao Xue; Thomas L. Saunders; Yanhong Guo; Chang L et al.
Source: Self-asserted source
Guizhen Zhao

PRDM16 deficiency in vascular smooth muscle cells aggravates abdominal aortic aneurysm.

JCI insight
2023-06-08 | Journal article
Contributors: Zhenguo Wang; Zhao X; Zhao G; Yanhong Guo; Haocheng Lu; Mu W; Zhong J; Garcia-Barrio M; Zhang J; Chen YE et al.
Source: Self-asserted source
Guizhen Zhao

BAF60c prevents abdominal aortic aneurysm formation through epigenetic control of vascular smooth muscle cell homeostasis

Journal of Clinical Investigation
2022-11-01 | Journal article | Author
Part of ISSN: 1558-8238
Contributors: Guizhen Zhao; Yang Zhao; Haocheng Lu; Ziyi; Hongyu Liu; Huilun Wang; Wenying Liang; Yuhao Liu; Tianqing Zhu; Oren Rom et al.
Source: Self-asserted source
Guizhen Zhao

Mouse Abdominal Aortic Aneurysm Model Induced by Perivascular Application of Elastase.

Journal of visualized experiments : JoVE
2022-02-11 | Journal article
Contributors: Chao Xue; Zhao G; Zhao Y; Chen YE; Zhang J
Source: Self-asserted source
Guizhen Zhao

KLF11 Protects against Venous Thrombosis via Suppressing Tissue Factor Expression.

Thrombosis and haemostasis
2021-08-24 | Journal article
Contributors: Wenying Liang; Lu H; Sun J; Zhao G; Wang H; Guo Y; Eitzman D; Chen YE; Yanbo Fan; Zhang J
Source: Self-asserted source
Guizhen Zhao

Nidogen-2 Maintains the Contractile Phenotype of Vascular Smooth Muscle Cells and Prevents Neointima Formation via Bridging Jagged1-Notch3 Signaling.

Circulation
2021-07-28 | Journal article
Contributors: Mao C; Ma Z; Yiting Jia; Weihao Li; Xie N; Zhao G; Ma B; Yu F; Sun J; Zhou Y et al.
Source: Self-asserted source
Guizhen Zhao

Dysregulated oxalate metabolism is a driver and therapeutic target in atherosclerosis.

Cell reports
2021-07-01 | Journal article
Contributors: Liu Y; Zhao Y; Yousef Shukha; Lu H; Wang L; Liu Z; Liu C; Zhao Y; Wang H; Zhao G et al.
Source: Self-asserted source
Guizhen Zhao

Single-Cell Transcriptomics Reveals Endothelial Plasticity During Diabetic Atherogenesis.

Frontiers in cell and developmental biology
2021-05-19 | Journal article
Contributors: Zhao G; Lu H; Yuhao Liu; Zhao Y; Zhu T; Garcia-Barrio MT; Chen YE; Zhang J
Source: Self-asserted source
Guizhen Zhao

Single-cell RNA sequencing reveals the cellular heterogeneity of aneurysmal infrarenal abdominal aorta.

Cardiovascular research
2021-04-01 | Journal article
Contributors: Zhao G; Haocheng Lu; Chang Z; Zhao Y; Zhu T; Chang L; Guo Y; Garcia-Barrio MT; Chen YE; Zhang J
Source: Self-asserted source
Guizhen Zhao

KLF11 protects against abdominal aortic aneurysm through inhibition of endothelial cell dysfunction.

JCI insight
2021-03-08 | Journal article
Contributors: Zhao G; Chang Z; Zhao Y; Yanhong Guo; Haocheng Lu; Wenying Liang; Oren Rom; Huilun Wang; Sun J; Zhu T et al.
Source: Self-asserted source
Guizhen Zhao

Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury.

Cell research
2021-01-28 | Journal article
Contributors: Fu Y; Huang Y; Yang Z; Chen Y; Jingang Zheng; Mao C; Li Z; Liu Z; Yu B; Li T et al.
Source: Self-asserted source
Guizhen Zhao
grade
Preferred source (of 2)‎

Endothelial TFEB (Transcription Factor EB) Improves Glucose Tolerance via Upregulation of IRS (Insulin Receptor Substrate) 1 and IRS2.

Arteriosclerosis, thrombosis, and vascular biology
2020-12-10 | Journal article
Contributors: Sun J; Haocheng Lu; Wenying Liang; Zhao G; Ren L; Hu D; Chang Z; Liu Y; Garcia-Barrio MT; Zhang J et al.
Source: Self-asserted source
Guizhen Zhao

Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome.

Science translational medicine
2020-12-01 | Journal article
Contributors: Oren Rom; Liu Y; Liu Z; Ying Zhao; Jianfeng Wu; Alia Ghrayeb; Luis Villacorta; Yanbo Fan; Chang L; Wang L et al.
Source: Self-asserted source
Guizhen Zhao
grade
Preferred source (of 2)‎

BAF60a Deficiency in Vascular Smooth Muscle Cells Prevents Abdominal Aortic Aneurysm by Reducing Inflammation and Extracellular Matrix Degradation.

Arteriosclerosis, thrombosis, and vascular biology
2020-08-13 | Journal article
Contributors: Chang Z; Zhao G; Zhao Y; Haocheng Lu; Xiong W; Wenying Liang; Sun J; Huilun Wang; Zhu T; Rom O et al.
Source: Self-asserted source
Guizhen Zhao

Suppression of Vascular Macrophage Activation by Nitro-Oleic Acid and its Implication for Abdominal Aortic Aneurysm Therapy.

Cardiovascular drugs and therapy
2020-07-15 | Journal article
Contributors: Zhao Y; Chang Z; Zhao G; Haocheng Lu; Xiong W; Wenying Liang; Wang H; Luis Villacorta; Garcia-Barrio MT; Zhu T et al.
Source: Self-asserted source
Guizhen Zhao

Cyclodextrin Prevents Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell Transcription Factor EB.

Circulation
2020-05-01 | Journal article
Contributors: Haocheng Lu; Sun J; Wenying Liang; Chang Z; Rom O; Zhao Y; Zhao G; Xiong W; Wang H; Zhu T et al.
Source: Self-asserted source
Guizhen Zhao

Postnatal deficiency of ADAMTS1 ameliorates thoracic aortic aneurysm and dissection in mice.

Experimental physiology
2018-10-17 | Journal article
Contributors: Wang S; Liu Y; Zhao G; He L; Fu Y; Yu C; Wang Z; Zhao T; Cao F; Gao Y et al.
Source: Self-asserted source
Guizhen Zhao

Rapamycin prevents thoracic aortic aneurysm and dissection in mice.

Journal of vascular surgery
2018-09-22 | Journal article
Contributors: Zhou B; Li W; Zhao G; Yu B; Ma B; Liu Z; Xie N; Fu Y; Gong Z; Dai R et al.
Source: Self-asserted source
Guizhen Zhao

Cartilage oligomeric matrix protein is a novel notch ligand driving embryonic stem cell differentiation towards the smooth muscle lineage.

Journal of molecular and cellular cardiology
2018-07-04 | Journal article
Contributors: Ma B; Yao F; Xie N; Mao C; Liu F; Gong Z; Zhao G; Liu Z; Cai Z; Yu F et al.
Source: Self-asserted source
Guizhen Zhao

Novel Adipokine, FAM19A5, Inhibits Neointima Formation After Injury Through Sphingosine-1-Phosphate Receptor 2.

Circulation
2018-02-16 | Journal article
Contributors: Wang Y; Chen D; Zhang Y; Wang P; Zheng C; Zhang S; Yu B; Zhang L; Zhao G; Ma B et al.
Source: Self-asserted source
Guizhen Zhao

Unspliced XBP1 Confers VSMC Homeostasis and Prevents Aortic Aneurysm Formation via FoxO4 Interaction.

Circulation research
2017-10-31 | Journal article
Contributors: Zhao G; Fu Y; Cai Z; Yu F; Gong Z; Dai R; Hu Y; Lingfang Zeng; Xu Q; wei kong
Source: Self-asserted source
Guizhen Zhao

Peer review (4 reviews for 1 publication/grant)

Review activity for Cardiovascular drugs and therapy. (4)