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Works (49)

Multiple Myeloma Insights from Single-Cell Analysis: Clonal Evolution, the Microenvironment, Therapy Evasion, and Clinical Implications

Cancers
2025-02-14 | Journal article
DOI: 10.3390/cancers17040653
Contributors: Sihong Li; Jiahui Liu; Madeline Peyton; Olivia Lazaro; Sean D. McCabe; Xiaoqing Huang; Yunlong Liu; Zanyu Shi; Zhiqi Zhang; Brian A. Walker et al.
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Polygenic risk for alcohol use disorder affects cellular responses to ethanol exposure in a human microglial cell model

Science Advances
2024-11-08 | Journal article
DOI: 10.1126/sciadv.ado5820
Contributors: Xindi Li; Jiayi Liu; Andrew J. Boreland; Sneha Kapadia; Siwei Zhang; Alessandro C. Stillitano; Yara Abbo; Lorraine Clark; Dongbing Lai; Yunlong Liu et al.
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Crossref

Data from Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2

2024-11-04 | Preprint
DOI: 10.1158/1535-7163.c.7522906
Contributors: Weini Wang; Yanchi Zhou; Ji Wang; Shu Zhang; Ali Ozes; Hongyu Gao; Fang Fang; Yue Wang; Xiaona Chu; Yunlong Liu et al.
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Crossref

Figure S1 from Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2

2024-11-04 | Preprint
DOI: 10.1158/1535-7163.27601798
Contributors: Weini Wang; Yanchi Zhou; Ji Wang; Shu Zhang; Ali Ozes; Hongyu Gao; Fang Fang; Yue Wang; Xiaona Chu; Yunlong Liu et al.
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Figure S2 from Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2

2024-11-04 | Preprint
DOI: 10.1158/1535-7163.27601795
Contributors: Weini Wang; Yanchi Zhou; Ji Wang; Shu Zhang; Ali Ozes; Hongyu Gao; Fang Fang; Yue Wang; Xiaona Chu; Yunlong Liu et al.
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Figure S3 from Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2

2024-11-04 | Preprint
DOI: 10.1158/1535-7163.27601789
Contributors: Weini Wang; Yanchi Zhou; Ji Wang; Shu Zhang; Ali Ozes; Hongyu Gao; Fang Fang; Yue Wang; Xiaona Chu; Yunlong Liu et al.
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Figure S4 from Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2

2024-11-04 | Preprint
DOI: 10.1158/1535-7163.27601786
Contributors: Weini Wang; Yanchi Zhou; Ji Wang; Shu Zhang; Ali Ozes; Hongyu Gao; Fang Fang; Yue Wang; Xiaona Chu; Yunlong Liu et al.
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Figure S5 from Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2

2024-11-04 | Preprint
DOI: 10.1158/1535-7163.27601780
Contributors: Weini Wang; Yanchi Zhou; Ji Wang; Shu Zhang; Ali Ozes; Hongyu Gao; Fang Fang; Yue Wang; Xiaona Chu; Yunlong Liu et al.
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Supplementary Table 1 from Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2

2024-11-04 | Preprint
DOI: 10.1158/1535-7163.27601777
Contributors: Weini Wang; Yanchi Zhou; Ji Wang; Shu Zhang; Ali Ozes; Hongyu Gao; Fang Fang; Yue Wang; Xiaona Chu; Yunlong Liu et al.
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Supplementary Table 2 from Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2

2024-11-04 | Preprint
DOI: 10.1158/1535-7163.27601774
Contributors: Weini Wang; Yanchi Zhou; Ji Wang; Shu Zhang; Ali Ozes; Hongyu Gao; Fang Fang; Yue Wang; Xiaona Chu; Yunlong Liu et al.
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Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2

Molecular Cancer Therapeutics
2024-11-04 | Journal article
DOI: 10.1158/1535-7163.MCT-23-0314
Contributors: Weini Wang; Yanchi Zhou; Ji Wang; Shu Zhang; Ali Ozes; Hongyu Gao; Fang Fang; Yue Wang; Xiaona Chu; Yunlong Liu et al.
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The Loss of PPARγ Expression and Signaling Is a Key Feature of Cutaneous Actinic Disease and Squamous Cell Carcinoma: Association with Tumor Stromal Inflammation

Cells
2024-08-15 | Journal article
DOI: 10.3390/cells13161356
Contributors: Raymond L. Konger; Xiaoling Xuei; Ethel Derr-Yellin; Fang Fang; Hongyu Gao; Yunlong Liu
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Loss of PPARγ Expression and Signaling Is a Key Feature of Cutaneous Actinic Disease and Squamous Cell Carcinoma: Association With Tumor Stromal Inflammation

2024-07-02 | Preprint
DOI: 10.20944/preprints202407.0153.v1
Contributors: Raymond L Konger; Xiaoling Xuei; Ethel Derr-Yellin; Fang Fang; Hongyu Gao; Yunlong Liu
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In silico generation and augmentation of regulatory variants from massively parallel reporter assay using conditional variational autoencoder

2024-06-29 | Preprint
DOI: 10.1101/2024.06.25.600715
Contributors: Weijia Jin; Yi Xia; Sai Ritesh Thela; Yunlong Liu; Li Chen
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MPRAVarDB: an online database and web server for exploring regulatory effects of genetic variants

2024-04-03 | Preprint
DOI: 10.1101/2024.04.02.587790
Contributors: Javlon Nizomov; Weijia Jin; Yi Xia; Yunlong Liu; Zhigang Li; Li Chen
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Spatial Transcriptomics of Spinal Ependymoma in NF2-related Schwannomatosis

2024-03-06 | Preprint
DOI: 10.1101/2024.03.03.583240
Contributors: Noah Burket; Jia Wang; Hongyu Gao; Robert Bell; Chi Zhang; Yunlong Liu; Wade Clapp; Jignesh Tailor
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Osteogenic Differentiation Potential of Mesenchymal Stem Cells Using Single Cell Multiomic Analysis

Genes
2023-09 | Journal article | Author
DOI: 10.3390/genes14101871
Contributors: Duojiao Chen; Sheng Liu; Xiaona Chu; Jill Reiter; Hongyu Gao; Patrick McGuire; Xuhong Yu; Xiaoling Xuei; Yichen Liu; Jun Wan et al.
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Multidisciplinary Digital Publishing Institute

Critical Role of Novel O-GlcNAcylation of S550 and S551 on the p65 Subunit of NF-κB in Pancreatic Cancer

Cancers
2023-09-27 | Journal article
DOI: 10.3390/cancers15194742
Contributors: Aishat Motolani; Matthew Martin; Benlian Wang; Guanglong Jiang; Faranak Alipourgivi; Xiumei Huang; Ahmad Safa; Yunlong Liu; Tao Lu
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Genetic Regulation of Human isomiR Biogenesis

Cancers
2023-09-04 | Journal article
DOI: 10.3390/cancers15174411
Contributors: Guanglong Jiang; Jill L. Reiter; Chuanpeng Dong; Yue Wang; Fang Fang; Zhaoyang Jiang; Yunlong Liu
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RNA alternative splicing impacts the risk for alcohol use disorder

Molecular Psychiatry
2023-07 | Journal article
DOI: 10.1038/s41380-023-02111-1
Contributors: Rudong Li; Jill L. Reiter; Andy B. Chen; Steven X. Chen; Tatiana Foroud; Howard J. Edenberg; Dongbing Lai; Yunlong Liu
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BRCA1 and BRCA2 germline mutations driven signaling pathway alterations are sufficient to initiate breast tumorigenesis by the PIK3CAH1047Roncogene

2023-07-27 | Preprint
DOI: 10.1101/2023.07.26.550741
Contributors: Poornima Bhat-Nakshatri; Aditi Khatpe; Duojiao Chen; Katie Batic; Henry Mang; Christopher Herodotou; Patrick C. McGuire; Xiaoling Xuei; Hongyu Gao; Yunlong Liu et al.
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Crossref

Genetic regulation of human isomiR biogenesis

2023-07-18 | Preprint
DOI: 10.20944/preprints202307.1185.v1
Contributors: Guanglong Jiang; Jill L. Reiter; Chuanpeng Dong; Yue Wang; Fang Fang; Zhaoyang Jiang; Yunlong Liu
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Single cell RNA analysis of the left–right organizer transcriptome reveals potential novel heterotaxy genes

Scientific Reports
2023-07-01 | Journal article
DOI: 10.1038/s41598-023-36862-2
Contributors: Helen M. Bellchambers; Amruta R. Phatak; Mardi J. Nenni; Maria B. Padua; Hongyu Gao; Yunlong Liu; Stephanie M. Ware
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Crossref

Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2

2023-06-28 | Preprint
DOI: 10.1101/2023.06.26.546524
Contributors: Weini Wang; Yanchi Zhou; Ji Wang; Shu Zhang; Ali Ozes; Hongyu Gao; Fang Fang; Yue Wang; Xiaona Chu; Yunlong Liu et al.
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Crossref

Origin, prospective identification, and function of circulating endothelial colony-forming cells in mice and humans

JCI Insight
2023-03-08 | Journal article
DOI: 10.1172/jci.insight.164781
Contributors: Yang Lin; Kimihiko Banno; Chang-Hyun Gil; Jered Myslinski; Takashi Hato; William C. Shelley; Hongyu Gao; Xiaoling Xuei; Yunlong Liu; David P. Basile et al.
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RNA alternative splicing impacts the risk for alcohol use disorder

2023-01-05 | Preprint
DOI: 10.21203/rs.3.rs-2260708/v1
Contributors: Yunlong Liu; Rudong Li; Jill Reiter; Andy Chen; Steven Chen; Tatiana Foroud; Howard Edenberg; Dongbing Lai
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Crossref

Bioinformatics detection of modulators controlling splicing factor‐dependent intron retention in the human brain

Human Mutation
2022-11 | Journal article
DOI: 10.1002/humu.24379
Contributors: Steven X. Chen; Ed Simpson; Jill L. Reiter; Yunlong Liu
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Origin, Prospective Identification, and Function of Circulating Endothelial Colony Forming Cells in Mouse and Human

2022-08-01 | Preprint
DOI: 10.1101/2022.07.31.502241
Contributors: Yang Lin; Kimihiko Banno; Chang-Hyun Gil; Jered Myslinski; Takashi Hato; William C. Shelley; Hongyu Gao; Xiaoling Xuei; Yunlong Liu; David P. Basile et al.
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Crossref

Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans

Translational Psychiatry
2022-07-05 | Journal article
DOI: 10.1038/s41398-022-02029-2
Contributors: Dongbing Lai; Tae-Hwi Schwantes-An; Marco Abreu; Grace Chan; Victor Hesselbrock; Chella Kamarajan; Yunlong Liu; Jacquelyn L. Meyers; John I. Nurnberger, Jr; Martin H. Plawecki et al.
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Crossref

Gene Expression Alterations in Peripheral Blood Following Sport-Related Concussion in a Prospective Cohort of Collegiate Athletes: A Concussion Assessment, Research and Education (CARE) Consortium Study

2022-06-28 | Preprint
DOI: 10.21203/rs.3.rs-1753658/v1
Contributors: Yunlong Liu; Edward Simpson; Kelly Nudelman; Larry Riggen; Michael Menser; Jie Ren; Jill Reiter; Jaroslaw Harezlak; Tatiana Foroud; Andrew Saykin et al.
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Using VBIM Technique to Discover ARMC4/ODAD2 as a Novel Negative Regulator of NF-κB and a New Tumor Suppressor in Colorectal Cancer

International Journal of Molecular Sciences
2022-03-01 | Journal article
DOI: 10.3390/ijms23052732
Contributors: Matthew Martin; Rasika Mundade; Antja-Voy Hartley; Guanglong Jiang; Jiamin Jin; Steven Sun; Ahmad Safa; George Sandusky; Yunlong Liu; Tao Lu
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AIscEA: Unsupervised Integration of Single-cell Gene Expression and Chromatin Accessibility via Their Biological Consistency

2022-02-19 | Preprint
DOI: 10.1101/2022.02.17.480279
Contributors: Elham Jafari; Travis Johnson; Yue Wang; Yunlong Liu; Kun Huang; Yijie Wang
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Crossref

Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity

Science Advances
2022-01-14 | Journal article
DOI: 10.1126/sciadv.abh3375
Contributors: Brijesh Kumar; Adedeji K. Adebayo; Mayuri Prasad; Maegan L. Capitano; Ruizhong Wang; Poornima Bhat-Nakshatri; Manjushree Anjanappa; Edward Simpson; Duojiao Chen; Yunlong Liu et al.
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Crossref

The impact of SBF2 on taxane-induced peripheral neuropathy

PLOS Genetics
2022-01-05 | Journal article
DOI: 10.1371/journal.pgen.1009968
Contributors: Geneva M. Cunningham; Harry T. Orr; Fei Shen; Xi Wu; Erica L. Cantor; Laura Gardner; Santosh Philips; Guanglong Jiang; Casey L. Bales; Zhiyong Tan et al.
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Crossref

Differential Splicing of Skipped Exons Predicts Drug Response in Cancer Cell Lines

Genomics, Proteomics & Bioinformatics
2021-12 | Journal article
DOI: 10.1016/j.gpb.2019.08.003
Contributors: Edward Simpson; Steven Chen; Jill L. Reiter; Yunlong Liu
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Crossref

Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases

Nature Communications
2021-08-20 | Journal article
DOI: 10.1038/s41467-021-25392-y
Contributors: Manav Kapoor; Michael J. Chao; Emma C. Johnson; Gloriia Novikova; Dongbing Lai; Jacquelyn L. Meyers; Jessica Schulman; John I. Nurnberger, Jr; Bernice Porjesz; Yunlong Liu et al.
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Heterogeneity of Hepatic Stellate Cells in Fibrogenesis of the Liver: Insights from Single-Cell Transcriptomic Analysis in Liver Injury

Cells
2021-08-19 | Journal article
DOI: 10.3390/cells10082129
Contributors: Wenjun Zhang; Simon J. Conway; Ying Liu; Paige Snider; Hanying Chen; Hongyu Gao; Yunlong Liu; Kadir Isidan; Kevin J. Lopez; Gonzalo Campana et al.
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Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin

International Journal of Molecular Sciences
2021-08-11 | Journal article
DOI: 10.3390/ijms22168634
Contributors: Raymond L. Konger; Ethel Derr-Yellin; Teresa A. Zimmers; Terrence Katona; Xiaoling Xuei; Yunlong Liu; Hong-Ming Zhou; Ed Ronald Simpson, Jr.; Matthew J. Turner
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Profiling of Adipose and Skeletal Muscle in Human Pancreatic Cancer Cachexia Reveals Distinct Gene Profiles with Convergent Pathways

Cancers
2021-04 | Journal article | Author
DOI: 10.3390/cancers13081975
Contributors: Ashok Narasimhan; Xiaoling Zhong; Ernie P. Au; Eugene P. Ceppa; Atilla Nakeeb; Michael G. House; Nicholas J. Zyromski; C. Max Schmidt; Katheryn N. H. Schloss; Daniel E. I. Schloss et al.
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Multidisciplinary Digital Publishing Institute

A critical role of AREG for bleomycin-induced skin fibrosis

2021-01-21 | Preprint
DOI: 10.1101/2021.01.20.427509
Contributors: Mary Yinghua Zhang; Shuyi Fang; Hongyu Gao; Xiaoli Zhang; Dongsheng Gu; Yunlong Liu; Jun Wan; Jingwu Xie
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Crossref

Identification of Functional Genetic Variants Associated With Alcohol Dependence and Related Phenotypes Using a High‐Throughput Assay

Alcoholism: Clinical and Experimental Research
2020-12 | Journal article
DOI: 10.1111/acer.14492
Contributors: Kriti S. Thapa; Andy B. Chen; Dongbing Lai; Xiaoling Xuei; Leah Wetherill; Jay A. Tischfield; Yunlong Liu; Howard J. Edenberg
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Crossref

Multi-omics integration analysis identifies novel genes for alcoholism with potential link to neurodegenerative diseases

2020-10-16 | Preprint
DOI: 10.1101/2020.10.15.341750
Contributors: Manav Kapoor; Michael Chao; Emma C. Johnson; Gloriia Novikova; Dongbing Lai; Jacquelyn Meyers; Jessica Schulman; John I Nurnberger, Jr; Bernice Porjesz; Yunlong Liu et al.
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Crossref

IL-6 Trans-Signaling and Crosstalk Among Tumor, Muscle and Fat Mediate Pancreatic Cancer Cachexia

2020-09-17 | Preprint
DOI: 10.1101/2020.09.16.300798
Contributors: Joseph E. Rupert; Andrea Bonetto; Ashok Narasimhan; Yunlong Liu; Thomas M. O’Connell; Leonidas G. Koniaris; Teresa A. Zimmers
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Crossref

INPP5Dexpression is associated with risk for Alzheimer’s disease and induced by plaque-associated microglia

2020-08-31 | Preprint
DOI: 10.1101/2020.08.31.276444
Contributors: Andy P. Tsai; Peter Bor-Chian Lin; Chuanpeng Dong; Miguel Moutinho; Brad T. Casali; Yunlong Liu; Bruce T. Lamb; Gary E. Landreth; Adrian L. Oblak; Kwangsik Nho
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A single cell atlas of the healthy breast tissues reveal clinically relevant clusters of breast epithelial cells

2020-06-26 | Preprint
DOI: 10.1101/2020.06.25.171793
Contributors: Poornima Bhat-Nakshatri; Hongyu Gao; Patrick C. McGuire; Xiaoling Xuei; Liu Sheng; Jun Wan; Yunlong Liu; Sandra K. Althouse; Austyn Colter; George Sandusky et al.
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Crossref

Bmi1 Maintains the Self-Renewal Property of Innate-like B Lymphocytes

The Journal of Immunology
2020-06-15 | Journal article
DOI: 10.4049/jimmunol.2000030
Contributors: Michihiro Kobayashi; Yang Lin; Akansha Mishra; Chris Shelly; Rui Gao; Colton W Reeh; Paul Zhiping Wang; Rongwen Xi; Yunlong Liu; Pamela Wenzel et al.
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Crossref

The orchestrated cellular and molecular responses of the kidney to endotoxin define the sepsis timeline

2020-05-30 | Preprint
DOI: 10.1101/2020.05.27.118620
Contributors: Danielle Janosevic; Jered Myslinski; Thomas McCarthy; Amy Zollman; Farooq Syed; Xiaoling Xuei; Hongyu Gao; Yunlong Liu; Kimberly S. Collins; Ying-Hua Cheng et al.
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Crossref

RNA Polymerase II CTD phosphatase Rtr1 fine-tunes transcription termination

PLOS Genetics
2020-03-18 | Journal article
DOI: 10.1371/journal.pgen.1008317
Contributors: Jose F. Victorino; Anita Corbett; Melanie J. Fox; Whitney R. Smith-Kinnaman; Sarah A. Peck Justice; Katlyn H. Burriss; Asha K. Boyd; Megan A. Zimmerly; Rachel R. Chan; Gerald O. Hunter et al.
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Crossref

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

Translational Psychiatry
2019-02-14 | Journal article
DOI: 10.1038/s41398-019-0384-y
Contributors: Manav Kapoor; Jen-Chyong Wang; Sean P. Farris; Yunlong Liu; Jeanette McClintick; Ishaan Gupta; Jacquelyn L. Meyers; Sarah Bertelsen; Michael Chao; John Nurnberger et al.
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Peer review (3 reviews for 3 publications/grants)

Review activity for Cell genomics. (1)
Review activity for Genome biology. (1)
Review activity for Nature reviews. (1)
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