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Biography
My research program is focused on understanding how gut immune systems interface with the environment, specifically the microbial components, i.e., the microbiome, and how these interactions shape immune (and developmental) ontogeny. We also study why lysogenized bacteria, or those that carry “dormant” viruses or prophages, matter within animal microbiomes. While I am focused on understanding how secreted immune effectors evolved to shape the ecology of microbiomes, the long-term interest is to contribute to our understanding of not just the evolution of gut immunity across phyla but also how exposure to diverse microbes shapes animal development and immune maturation, and this applies to human infants (especially those born prematurely). Our research leverages simpler model systems and focuses on premature infants in the neonatal intensive care unit to address these questions better.
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2226050
Works (50 of 51)
2-s2.0-85084342461
15526909 08842175
2-s2.0-85084344199
20726643
2-s2.0-85078679095
14765543 07438346
2-s2.0-84946570026
18610412 00801844
10.1038/srep09637
WOS:000354307600001
10.1038/srep08693
WOS:000350350500014
2-s2.0-84938484921
20492618
10.1371/journal.pone.0094984
WOS:000336655700023
10.1016/j.dci.2014.06.011
WOS:000342275400005
10.1371/journal.pone.0093386
WOS:000334103000066
2-s2.0-84883812636
16643224
10.1016/j.cub.2013.08.048
WOS:000326317300015
2-s2.0-84874177229
16643224
10.1093/bfgp/els007
WOS:000301972300009
10.1073/pnas.1109687108
WOS:000295536000054
10.1007/978-1-61779-139-0_17
WOS:000292990200017
S1044-5323(09)00121-3 [pii] 10.1016/j.smim.2009.11.006
10.1007/s00251-010-0464-x
WOS:000281396500006
10.1007/s12026-009-8112-y
S0960-9822(09)00745-3 [pii] 10.1016/j.cub.2009.02.035
1471-2156-9-78 [pii] 10.1186/1471-2156-9-78
gb-2008-9-8-r123 [pii] 10.1186/gb-2008-9-8-r123
gr.073676.107 [pii] 10.1101/gr.073676.107
2-s2.0-48949100896
10889051 15495469
S0952-7915(07)00113-6 [pii] 10.1016/j.coi.2007.07.001
10.1016/j.clim.2007.03.299
WOS:000247137200111
10.1007/s12026-007-0014-2
WOS:000250372300034
10.1007/s00251-006-0105-6
WOS:000238014900014
10.1007/s00251-005-0005-1
WOS:000232340200007
nri1712 [pii] 10.1038/nri1712
WOS:000182367000510
WOS:000182367000242
WOS:000182367000513
10.1016/S1534-5807(03)00325-3
WOS:000186544400014
BIOSIS:PREV200200597360
WOS:000174533603786
98/22/12362 [pii] 10.1073/pnas.231310698
WOS:000167438103941